ES2039496T3 - Procedimiento de preparacion de retinoatos de amonio cuaternarios. - Google Patents

Procedimiento de preparacion de retinoatos de amonio cuaternarios.

Info

Publication number
ES2039496T3
ES2039496T3 ES198888107228T ES88107228T ES2039496T3 ES 2039496 T3 ES2039496 T3 ES 2039496T3 ES 198888107228 T ES198888107228 T ES 198888107228T ES 88107228 T ES88107228 T ES 88107228T ES 2039496 T3 ES2039496 T3 ES 2039496T3
Authority
ES
Spain
Prior art keywords
denotes
image
retinoate
formula
quaternary ammonium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888107228T
Other languages
English (en)
Inventor
Michel Philippe
Henri Sebag
Didier Saint-Leger
Jean-Luc Leveque
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Application granted granted Critical
Publication of ES2039496T3 publication Critical patent/ES2039496T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

NUEVO RETINOATO DE AMONIO CUATERNARIO, CARACTERIZADO POR RESPONDER A LA FORMULA, EN LA CUAL X(THETA) DESIGNA: - BIEN UN RETINOATO ALL TRANS DE LA FORMULA (II); - BIEN UN RETINOATO 13 - CIS DE FORMULA (III); (I) R1, R2, R3 IDENTICOS O DIFERENTES, DESIGNAN UN AGRUPAMIENTO ALCOHIL LINEAL SATURADO EN C1 - C4 PUDIENDO LLEVAR EN EXTREMO DE CADENA O EN LA CADENA UNO O VARIOS AGRUPAMIENTO(S) HIDROXILO(S); R4 DESIGNA UN AGRUPAMIENTO ALCOHIL O ALCENIL LINEAL EN C12 - C18; (II) R3 DESIGNA EL AGRUPAMIENTO, EN EL CUAL: N ES IGUAL A 0 O 1, RS REPRESENTA UN ATOMO DE HIDROGENO, UN HIDROXIL, UN ATOMO DE HALOGENO, UN AGRUPAMIENTO ALCOHIL O UN HIDROXIALCOHIL EN C1 A C18 O UN AGRUPAMIENTO ACIL EN C2 A C18; R1, R2 Y R4 TENIENDO LOS MISMOS SIGNIFICADOS QUE EN (I); (III) R1 Y R2 PUEDEN FORMAR UN HETEROCICLO ALIFATICO COMPORTANDO EVENTUALMENTE UN ATOMO DE OXIGENO, OTRO DE NITROGENO O UN ATOMO DE AZUFRE, R3 Y R4 TENIENDO LOS MISMOS SIGNIFICADOS QUE EN (I) Y (II).
ES198888107228T 1987-05-06 1988-05-05 Procedimiento de preparacion de retinoatos de amonio cuaternarios. Expired - Lifetime ES2039496T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU86865A LU86865A1 (fr) 1987-05-06 1987-05-06 Nouveaux retinoates d'ammonium quaternaires,leur utilisation en cosmetique et en dermopharmacie

Publications (1)

Publication Number Publication Date
ES2039496T3 true ES2039496T3 (es) 1993-10-01

Family

ID=19730914

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888107228T Expired - Lifetime ES2039496T3 (es) 1987-05-06 1988-05-05 Procedimiento de preparacion de retinoatos de amonio cuaternarios.

Country Status (8)

Country Link
US (1) US4857525A (es)
EP (1) EP0290020B1 (es)
JP (1) JP2595036B2 (es)
AT (1) ATE74591T1 (es)
CA (1) CA1304740C (es)
DE (1) DE3869825D1 (es)
ES (1) ES2039496T3 (es)
LU (1) LU86865A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057502A (en) * 1987-06-02 1991-10-15 Walsh William E Composition and topical and systemic treatments of conditions caused by heavy, oily or greasy secretions
FR2647015B1 (fr) * 1989-05-17 1994-05-06 Cird Gel aqueux a base d'acide retinoique et son utilisation en medecine humaine et en cosmetique
US5470567A (en) * 1989-08-24 1995-11-28 Bristol Myers Squibb Company Synergistic skin depigmentation composition
FR2653015B1 (fr) * 1989-10-12 1993-10-29 Oreal Composition cosmetique ou pharmaceutique pour application topique contenant au moins un derive retinouide et au moins un derive de pyrimidine, son utilisation comme medicament et procede de traitement correspondant.
US5053024A (en) * 1989-10-23 1991-10-01 Israel Dvoretzky Application system and method for treating warts
ZA943999B (en) * 1993-06-09 1995-02-03 Lonza Ag Quaternary ammonium and waterproofing/preservative compositions
CA2489705C (en) * 2002-06-17 2012-08-14 Vicuron Pharmaceuticals Inc. Use of amide derivative of ge 2270 factor a3 for the treatment of acne
US8048919B2 (en) * 2004-06-28 2011-11-01 Archer Daniels Midland Company Use of ethyl lactate as an excipient for pharmaceutical compositions
CN115232048B (zh) * 2021-04-22 2024-02-27 南京毓浠医药技术有限公司 一种离子液体及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL58296C (es) * 1943-02-26 1946-08-16
FR1297730A (fr) * 1960-11-04 1962-07-06 Hoffmann La Roche Préparation cosmétique
US4214000A (en) * 1978-10-30 1980-07-22 Johnson & Johnson Zinc salt of all-trans-retinoic acid for the treatment of acne

Also Published As

Publication number Publication date
JP2595036B2 (ja) 1997-03-26
DE3869825D1 (de) 1992-05-14
CA1304740C (fr) 1992-07-07
ATE74591T1 (de) 1992-04-15
US4857525A (en) 1989-08-15
LU86865A1 (fr) 1989-01-19
JPS63287763A (ja) 1988-11-24
EP0290020B1 (fr) 1992-04-08
EP0290020A1 (fr) 1988-11-09

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