ES2038597T3 - Metodo para detectar anticuerpos neutralizantes de virus en una muestra acuosa. - Google Patents

Metodo para detectar anticuerpos neutralizantes de virus en una muestra acuosa.

Info

Publication number
ES2038597T3
ES2038597T3 ES198686402610T ES86402610T ES2038597T3 ES 2038597 T3 ES2038597 T3 ES 2038597T3 ES 198686402610 T ES198686402610 T ES 198686402610T ES 86402610 T ES86402610 T ES 86402610T ES 2038597 T3 ES2038597 T3 ES 2038597T3
Authority
ES
Spain
Prior art keywords
virus
disturbance
water sample
neutralizing antibodies
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198686402610T
Other languages
English (en)
Inventor
A. Gerard Quash
John Dennis Rodwell
Thomas Joseph Mckearn
Jean-Pierre Ripoll
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Cytogen Corp
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Cytogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8517377A external-priority patent/FR2590674B1/fr
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM, Cytogen Corp filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Application granted granted Critical
Publication of ES2038597T3 publication Critical patent/ES2038597T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

METODOS PARA DIAGNOSTICO, PROGNOSIS, PROFILAXIS Y TERAPIA DE LAS INFECCIONES VIRICAS DESCRITAS. LOS METODOS EMPLEAN UN VIRUS, ANTIGENO VIRICO O FRAGMENTOS DE ELLOS EN LOS CUALES LA "PERTURBACION" DE LA MITAD DESGARRADA DE UN OLIGOSACARIDO DEL VIRUS, ANTIGENO VIRICO, O FRAGMENTOS DE ELLOS MAS ESPECIFICAMENTE RECONOCIBLES O REACTIVOS CON ANTICUERPOS NEUTRALIZANTES. COMO ES DESCRITO LA "PERTURBACION" DE UNA MITAD DE OLIGOSACARIDO, ABARCA SIN MODIFICACION ALGUNA (1), ALTERAR LA ESTRUCTURA QUIMICA O FISICA DEL RESIDUO DE HIDRATO DE CARBONO QUE ESTA PRESENTE NATURALMENTE; (2) ELIMINAR TOTAL O PARCIALMENTE UN RESIDUO DE CARBOHIDRATO; Y (3) PREVENIR O ALTERAR LA ADICION DE RESIDUO DE CARBOHIDRATO. UNA VARIEDAD DE METODOS DE "PERTURBACION" DE OLIGOSACARIDOS SON TAMBIEN DESCRITOS.
ES198686402610T 1985-11-25 1986-11-25 Metodo para detectar anticuerpos neutralizantes de virus en una muestra acuosa. Expired - Lifetime ES2038597T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8517377A FR2590674B1 (fr) 1985-11-25 1985-11-25 Nouveaux reactifs de diagnostic
US06/928,631 US4853326A (en) 1985-11-25 1986-11-18 Carbohydrate perturbations of viruses or viral antigens and utilization for diagnostic prophylactic and/or therapeutic applications

Publications (1)

Publication Number Publication Date
ES2038597T3 true ES2038597T3 (es) 1993-08-01

Family

ID=26224838

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198686402610T Expired - Lifetime ES2038597T3 (es) 1985-11-25 1986-11-25 Metodo para detectar anticuerpos neutralizantes de virus en una muestra acuosa.

Country Status (8)

Country Link
EP (1) EP0229546B1 (es)
AT (1) ATE67314T1 (es)
AU (1) AU592142B2 (es)
DE (1) DE3681428D1 (es)
ES (1) ES2038597T3 (es)
FI (1) FI873233A (es)
GR (1) GR3003323T3 (es)
WO (1) WO1987003206A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863730A (en) * 1986-03-21 1989-09-05 Cenfold Holdings, S.A. Immunotherapy for AIDS patients
WO1989000196A1 (en) * 1987-06-30 1989-01-12 The Upjohn Company Virus proteins having reduced o-linked glycosylation
WO1989001339A1 (en) * 1987-08-11 1989-02-23 Regents Of The University Of Minnesota Hyper-immune globulin against hiv
US5164481A (en) * 1989-08-23 1992-11-17 Iaf Biochem International Inc. Peptides and analogues and mixtures thereof for detecting and eliciting antibodies to rubella virus
US5427792A (en) * 1989-08-23 1995-06-27 Biochem Immunosystems, Inc. Peptides, analogues and mixtures thereof for detecting and eliciting antibodies to the E1 and E2 protein of rubella virus
DE4025499A1 (de) * 1990-08-11 1992-02-13 Sandoz Ag Verwendung der antikoerper br55-2, deren derivate, konjugate und fragmente zur bekaempfung von hiv-infektionen
CA2538794C (en) 2003-09-12 2016-04-19 Antigenics, Inc. Vaccine for treatment and prevention of herpes simplex virus infection

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2378094A2 (fr) * 1977-01-24 1978-08-18 Inst Nat Sante Rech Med Nouveaux reactifs biologiques constitues par des supports solides sur lesquels sont couples des composes organiques comportant un residu glucidique
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
JPS54113492A (en) * 1978-02-24 1979-09-05 Sanyo Chem Ind Ltd Preparation of glucoprotein derivative
CA1203164A (en) * 1982-03-09 1986-04-15 Thomas J. Mckearn Antibody conjugates
JPS6011428A (ja) * 1983-02-01 1985-01-21 ジエネンテク，インコ−ポレイテツド 狂犬病ワクチン
FR2543570B1 (fr) * 1983-03-31 1985-08-09 Pasteur Institut Anticorps monoclonaux anticytomegalovirus humains, hybridomes secreteurs de ces anticorps et polypeptides porteurs d'un determinant antigenique sequentiel de cytomegalovirus humains
WO1984004327A1 (en) 1983-04-27 1984-11-08 Harvard College Method and products for detection of human t cell leukemia virus
US4634666A (en) * 1984-01-06 1987-01-06 The Board Of Trustees Of The Leland Stanford Junior University Human-murine hybridoma fusion partner
US4743553A (en) * 1984-07-18 1988-05-10 W. R. Grace & Co. Synthetic genes for bovine parainfluenza virus

Also Published As

Publication number Publication date
DE3681428D1 (de) 1991-10-17
FI873233A0 (fi) 1987-07-23
EP0229546B1 (en) 1991-09-11
GR3003323T3 (en) 1993-02-17
AU592142B2 (en) 1990-01-04
ATE67314T1 (de) 1991-09-15
WO1987003206A1 (en) 1987-06-04
AU6723187A (en) 1987-07-01
FI873233A (fi) 1987-07-23
EP0229546A1 (en) 1987-07-22

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