ES2037605A1 - Metodo para preparar nuevos agentes yodados no ionicos de constraste a los rayos x. - Google Patents

Metodo para preparar nuevos agentes yodados no ionicos de constraste a los rayos x.

Info

Publication number
ES2037605A1
ES2037605A1 ES919102552A ES9102552A ES2037605A1 ES 2037605 A1 ES2037605 A1 ES 2037605A1 ES 919102552 A ES919102552 A ES 919102552A ES 9102552 A ES9102552 A ES 9102552A ES 2037605 A1 ES2037605 A1 ES 2037605A1
Authority
ES
Spain
Prior art keywords
prepn
ray contrast
contrast agent
new
polyhydroxyalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES919102552A
Other languages
English (en)
Other versions
ES2037605B1 (es
Inventor
Jimenez Jose L Martin
Colon Jose Maria Carretero
Sanz Antonio Martinez
Silva Ignacio Alonso
Martinez Juan R Harto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Invest Justesa Imagen S A Cent
Original Assignee
Invest Justesa Imagen S A Cent
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Invest Justesa Imagen S A Cent filed Critical Invest Justesa Imagen S A Cent
Priority to ES9102552A priority Critical patent/ES2037605B1/es
Publication of ES2037605A1 publication Critical patent/ES2037605A1/es
Application granted granted Critical
Publication of ES2037605B1 publication Critical patent/ES2037605B1/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Abstract

LA INVENCION SE REFIERE A UN METODO PARA PREPARAR NUEVOS AGENTES YODADOS NO IONICOS DE CONTRASTE A LOS RAYOS X DE ESTRUCTURA DIMERICA Y DE FORMULA GENERAL I, EN LA QUE EL PUENTE DE UNION ES GLICINA O GLICINA N-SUSTITUIDA FORMULA DONDE RSI1 ES UN RESTO POLIHIDROXIALQUIL LINEAL O RAMIFICADO DE 2 A 4 ATOMOS DE CARBONO, RSI2 ES HIDROGENO, METILO O UN RESTO POLIHIDROXIALQUILO LINEAL DE 2 A 3 ATOMOS DE CARBONO, RSI3 Y RSI8 IGUALES O DIFERENTES SON HIDROGENO, METILO O 2-HIDROXIETILO, RSI4 ES UN RESTO POLIHIDROXIALQUILO LINEAL O RAMIFICADO DE 2 A 4 ATOMOS DE CARBONO, RSI5 ES METILO, HIDROXIMETILO O METOXIMETILO, Y RSI6 Y RSI7 IGUALES O DIFERENTES SON HIDROGENO, METILO, 2-HIDROXIETILO O 2,3-DIHIDROXIPROPILO, RSI2 Y RSI5 JUNTOS PUEDEN FORMAR UN GRUPO DEL TIPO FORMULA DONDE N PUEDE SER DE 0 A 3.
ES9102552A 1991-11-18 1991-11-18 Metodo para preparar nuevos agentes yodados no ionicos de constraste a los rayos x. Expired - Lifetime ES2037605B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9102552A ES2037605B1 (es) 1991-11-18 1991-11-18 Metodo para preparar nuevos agentes yodados no ionicos de constraste a los rayos x.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9102552A ES2037605B1 (es) 1991-11-18 1991-11-18 Metodo para preparar nuevos agentes yodados no ionicos de constraste a los rayos x.

Publications (2)

Publication Number Publication Date
ES2037605A1 true ES2037605A1 (es) 1993-06-16
ES2037605B1 ES2037605B1 (es) 1994-02-01

Family

ID=8274196

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9102552A Expired - Lifetime ES2037605B1 (es) 1991-11-18 1991-11-18 Metodo para preparar nuevos agentes yodados no ionicos de constraste a los rayos x.

Country Status (1)

Country Link
ES (1) ES2037605B1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115806498A (zh) * 2021-09-15 2023-03-17 大道隆达（北京）医药科技发展有限公司 5-氯乙酰胺基-2,4,6-三碘异酞酰氯的合成方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0015867A1 (de) * 1979-03-08 1980-09-17 Schering Aktiengesellschaft Trijodierte Isophthalsäurediamide, deren Herstellung und diese enthaltende Röntgenkontrastmittel
EP0308364A2 (de) * 1987-09-17 1989-03-22 Schering Aktiengesellschaft Neue Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-Triiodanilide), Verfahren zu deren Herstellung sowie diese enthaltende Röntgenkontrastmittel
EP0317492A2 (de) * 1987-11-16 1989-05-24 Schering Aktiengesellschaft Neue substituierte Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-triiodanilide), Verfahren zu deren Herstellung sowie diese enthaltende Röntgenkontrastmittel
EP0345163A1 (fr) * 1988-06-02 1989-12-06 Guerbet S.A. Nouveau composé triiodobenzénique non ionique iodé, son procédé de préparation et produit de contraste le contenant

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0015867A1 (de) * 1979-03-08 1980-09-17 Schering Aktiengesellschaft Trijodierte Isophthalsäurediamide, deren Herstellung und diese enthaltende Röntgenkontrastmittel
EP0308364A2 (de) * 1987-09-17 1989-03-22 Schering Aktiengesellschaft Neue Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-Triiodanilide), Verfahren zu deren Herstellung sowie diese enthaltende Röntgenkontrastmittel
EP0317492A2 (de) * 1987-11-16 1989-05-24 Schering Aktiengesellschaft Neue substituierte Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-triiodanilide), Verfahren zu deren Herstellung sowie diese enthaltende Röntgenkontrastmittel
EP0345163A1 (fr) * 1988-06-02 1989-12-06 Guerbet S.A. Nouveau composé triiodobenzénique non ionique iodé, son procédé de préparation et produit de contraste le contenant

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115806498A (zh) * 2021-09-15 2023-03-17 大道隆达（北京）医药科技发展有限公司 5-氯乙酰胺基-2,4,6-三碘异酞酰氯的合成方法

Also Published As

Publication number Publication date
ES2037605B1 (es) 1994-02-01

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