ES2036519T3 - Derivados de peroxidasa estabilizados solubles en agua, procedimiento para su preparacion y utilizacion. - Google Patents

Derivados de peroxidasa estabilizados solubles en agua, procedimiento para su preparacion y utilizacion.

Info

Publication number
ES2036519T3
ES2036519T3 ES198686115902T ES86115902T ES2036519T3 ES 2036519 T3 ES2036519 T3 ES 2036519T3 ES 198686115902 T ES198686115902 T ES 198686115902T ES 86115902 T ES86115902 T ES 86115902T ES 2036519 T3 ES2036519 T3 ES 2036519T3
Authority
ES
Spain
Prior art keywords
water
procedure
preparation
peroxidase
derivatives soluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198686115902T
Other languages
English (en)
Inventor
Wilhelm Dr. Dipl.-Ing. Tischer
Josef Heinle
Michael-Harold Dr.Rer.Nat. Town
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Application granted granted Critical
Publication of ES2036519T3 publication Critical patent/ES2036519T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)

Abstract

LA INVENCION SE REFIERE A DERIVADOS HIDROSOLUBLES ESTABILIZADOS DE PEROXIDASA QUE SE OBTIENEN POR OXIDACION DE DERIVADOS DE PEROXIDASA CON ACIDO PERYODICO O PERYODATO Y UNION CON UN POLIMERO HIDROSOLUBLE DEL GRUPO DE LOS POLISACARIDOS, POLIETILENGLICOL, POLIVINILPIRROLIDONA O POLIANHIDRIDO. SE TRATA ASIMISMO DE SU OBTENCION Y APLICACION. LA ACTIVIDAD DE ESTOS DERIVADOS DE PEROXIDASA ES ESTABLE EN SOLUCIONES QUE CONTIENEN DETERGENTES Y/O COMPLEJANTES.
ES198686115902T 1985-11-21 1986-11-15 Derivados de peroxidasa estabilizados solubles en agua, procedimiento para su preparacion y utilizacion. Expired - Lifetime ES2036519T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853541186 DE3541186A1 (de) 1985-11-21 1985-11-21 Wasserloesliche, stabilisierte peroxidasederivate, verfahren zu ihrer herstellung und verwendung zur bestimmung von wasserstoffperoxid

Publications (1)

Publication Number Publication Date
ES2036519T3 true ES2036519T3 (es) 1993-06-01

Family

ID=6286483

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198686115902T Expired - Lifetime ES2036519T3 (es) 1985-11-21 1986-11-15 Derivados de peroxidasa estabilizados solubles en agua, procedimiento para su preparacion y utilizacion.

Country Status (7)

Country Link
US (1) US4910135A (es)
EP (1) EP0223221B1 (es)
JP (1) JPS62126977A (es)
AT (1) ATE74961T1 (es)
DE (2) DE3541186A1 (es)
ES (1) ES2036519T3 (es)
GR (1) GR3004587T3 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2632518B2 (ja) * 1987-08-28 1997-07-23 天野製薬株式会社 ビリルビンオキシダーゼの化学修飾体
USRE39497E1 (en) * 1989-02-16 2007-02-27 Nektar Therapeutics Storage of materials
GB8903593D0 (en) * 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
US5013646A (en) * 1989-11-03 1991-05-07 Transgenic Sciences, Inc. TMB Formulation for soluble and precipitable HRP-ELISA
FR2656329A1 (fr) * 1989-12-21 1991-06-28 Elf Aquitaine Procede de production de peroxydases mn-dependantes.
US5112752A (en) * 1990-10-18 1992-05-12 The Mead Corporation Biocatalytic oxidation using soybean and other legume peroxidases
JP3125428B2 (ja) * 1991-03-28 2001-01-15 和光純薬工業株式会社 修飾酵素
AU659645B2 (en) 1991-06-26 1995-05-25 Inhale Therapeutic Systems Storage of materials
CA2091544A1 (en) * 1992-03-26 1993-09-27 Shing F. Kwan Stabilization of functional proteins
AU662235B2 (en) * 1992-09-04 1995-08-24 Becton Dickinson & Company Intrinsic factor - horseradish peroxidase conjugates
ATE254475T1 (de) * 1993-09-22 2003-12-15 Jackson H M Found Military Med Verfahren zur aktivierung von löslichem kohlenhydraten durch verwendung von neuen cyanylierungsreagenzien, zur herstellung von immunogenischen konstrukten
US5849301A (en) * 1993-09-22 1998-12-15 Henry M. Jackson Foundation For The Advancement Of Military Medicine Producing immunogenic constructs using soluable carbohydrates activated via organic cyanylating reagents
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
EP0796324A1 (en) * 1994-12-07 1997-09-24 Novo Nordisk A/S Polypeptide with reduced allergenicity
DE19506262A1 (de) * 1995-02-23 1996-08-29 Behringwerke Ag Störungsvermindertes Redox-Nachweissystem
DE122009000056I1 (de) * 1995-03-22 2010-01-28 Jackson H M Found Military Med Herstellung von immunogenen konstrukten unter verwendung von löslichen kohlehydraten, die durch organische cyanylierungs-reagenzien aktiviert wurden
NZ304715A (en) * 1995-03-22 1999-07-29 Jackson H M Found Military Med Production of immunogenic constructs using organic cyanylating reagents to activate carbohydrates and then coupling the carbohydrate to a protein, peptide or hapten
US6309671B1 (en) 1995-04-14 2001-10-30 Inhale Therapeutic Systems Stable glassy state powder formulations
GB9508691D0 (en) 1995-04-28 1995-06-14 Pafra Ltd Stable compositions
US6030933A (en) * 1995-12-29 2000-02-29 The Procter & Gamble Company Detergent compositions comprising immobilized enzymes
EP0894128A1 (en) * 1996-02-15 1999-02-03 Novo Nordisk A/S Conjugation of polypeptides
US6309646B1 (en) 1996-05-09 2001-10-30 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Protein-polysaccharide conjugate vaccines and other immunological reagents prepared using homobifunctional and heterobifunctional vinylsulfones, and processes for preparing the conjugates
CN103946704B (zh) 2011-08-26 2017-11-24 艾维亚纳分子技术有限公司 用于现场护理诊断使用的生物涂覆型压电生物传感器平台

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3860484A (en) * 1972-09-28 1975-01-14 Xerox Corp Enzyme stabilization
JPS536483A (en) * 1976-07-02 1978-01-20 Tanabe Seiyaku Co Ltd Composition having enzymatic activity and its preparation
GB2055847A (en) * 1979-07-30 1981-03-11 Bull F G Process for the production of carrier particles
US4652524A (en) * 1980-10-02 1987-03-24 Ivan E. Modrovich Soluble stabilized enzymes
DE3126759A1 (de) * 1981-07-07 1983-01-27 Boehringer Mannheim Gmbh, 6800 Mannheim Loesliche leber-uricase, verfahren zu ihrer herstellung und verwendung
JPS5951789A (ja) * 1982-09-18 1984-03-26 Wako Pure Chem Ind Ltd 安定化酵素

Also Published As

Publication number Publication date
ATE74961T1 (de) 1992-05-15
DE3541186A1 (de) 1987-05-27
DE3684879D1 (de) 1992-05-21
US4910135A (en) 1990-03-20
GR3004587T3 (es) 1993-04-28
JPS62126977A (ja) 1987-06-09
EP0223221A2 (de) 1987-05-27
JPS6355918B2 (es) 1988-11-04
EP0223221B1 (de) 1992-04-15
EP0223221A3 (en) 1989-03-08

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