ES2034117T3 - Formulacion de unguento con esteroide. - Google Patents
Formulacion de unguento con esteroide.Info
- Publication number
- ES2034117T3 ES2034117T3 ES198888118871T ES88118871T ES2034117T3 ES 2034117 T3 ES2034117 T3 ES 2034117T3 ES 198888118871 T ES198888118871 T ES 198888118871T ES 88118871 T ES88118871 T ES 88118871T ES 2034117 T3 ES2034117 T3 ES 2034117T3
- Authority
- ES
- Spain
- Prior art keywords
- beta
- alpha
- propylene glycol
- steroid
- impart
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 150000003431 steroids Chemical class 0.000 title abstract 2
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 6
- 239000002674 ointment Substances 0.000 abstract 3
- 239000004615 ingredient Substances 0.000 abstract 2
- 239000004322 Butylated hydroxytoluene Substances 0.000 abstract 1
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- DXEXNWDGDYUITL-FXSSSKFRSA-N Tipredane Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1CC[C@@](SC)(SCC)[C@@]1(C)C[C@@H]2O DXEXNWDGDYUITL-FXSSSKFRSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 235000010354 butylated hydroxytoluene Nutrition 0.000 abstract 1
- 229940095259 butylated hydroxytoluene Drugs 0.000 abstract 1
- 229940073669 ceteareth 20 Drugs 0.000 abstract 1
- 229940081733 cetearyl alcohol Drugs 0.000 abstract 1
- 239000002270 dispersing agent Substances 0.000 abstract 1
- 239000003974 emollient agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 1
- 150000004668 long chain fatty acids Chemical class 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 abstract 1
- 239000001508 potassium citrate Substances 0.000 abstract 1
- 229960002635 potassium citrate Drugs 0.000 abstract 1
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 abstract 1
- 235000011082 potassium citrates Nutrition 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000001509 sodium citrate Substances 0.000 abstract 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 abstract 1
- 229940001584 sodium metabisulfite Drugs 0.000 abstract 1
- 235000010262 sodium metabisulphite Nutrition 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000002562 thickening agent Substances 0.000 abstract 1
- 229950001669 tipredane Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/120,276 US4868168A (en) | 1987-11-13 | 1987-11-13 | Steroid ointment formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2034117T3 true ES2034117T3 (es) | 1993-04-01 |
Family
ID=22389282
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198888118871T Expired - Lifetime ES2034117T3 (es) | 1987-11-13 | 1988-11-11 | Formulacion de unguento con esteroide. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4868168A (enExample) |
| EP (1) | EP0316815B1 (enExample) |
| JP (1) | JPH01153641A (enExample) |
| AT (1) | ATE76576T1 (enExample) |
| CA (1) | CA1326448C (enExample) |
| DE (1) | DE3871494D1 (enExample) |
| ES (1) | ES2034117T3 (enExample) |
| GR (1) | GR3005443T3 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4883660A (en) * | 1988-10-17 | 1989-11-28 | Thames Pharmacal Co., Inc. | Gel bases for pharmaceutical compositions |
| US5432170A (en) * | 1991-07-16 | 1995-07-11 | Schering Aktiengesellschaft | Process for the production of semisolid preparations containing micronized active ingredients |
| WO2006051819A1 (ja) * | 2004-11-10 | 2006-05-18 | Hisamitsu Pharmaceutical Co., Inc. | 外用製剤及び貼付剤 |
| US20080299182A1 (en) * | 2007-03-01 | 2008-12-04 | Shuyuan Zhang | Methods and formulations for topical gene therapy |
| CN102281863B (zh) * | 2009-01-16 | 2015-08-19 | 新科蒂斯公司 | 集钙作用组合物以及用于治疗皮肤的色素沉着障碍以及病症的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2801202A (en) * | 1954-12-24 | 1957-07-30 | Smith Kline French Lab | Compositions containing cortisone or hydrocortisone with phenylephrine |
| US3592930A (en) * | 1968-07-19 | 1971-07-13 | Syntex Corp | Moisture-deterioratable topical medicaments,particularly anti-inflammatory steroids,in a substantially non-aqueous fatty alcohol-propylene glycol vehicle |
| GB1382614A (en) * | 1972-01-10 | 1975-02-05 | Squibb & Sons Inc | Steroid compositions |
| US4048310A (en) * | 1976-02-24 | 1977-09-13 | E. R. Squibb & Sons, Inc. | Topical steroid formulation in form of lotion or cream |
| US4233295A (en) * | 1979-05-31 | 1980-11-11 | E. R. Squibb & Sons, Inc. | Corticosteroid formulations containing sebacate carrier |
| NZ200918A (en) * | 1981-07-02 | 1985-07-31 | Gist Brocades Nv | Stable fatty oil-in-water emulsion cream for topical application |
| US4361559A (en) * | 1981-08-20 | 1982-11-30 | E. R. Squibb & Sons, Inc. | Antiinflammatory 17,17-bis (substituted thio) androstenes |
-
1987
- 1987-11-13 US US07/120,276 patent/US4868168A/en not_active Expired - Fee Related
-
1988
- 1988-10-12 CA CA000579960A patent/CA1326448C/en not_active Expired - Lifetime
- 1988-11-11 DE DE8888118871T patent/DE3871494D1/de not_active Expired - Lifetime
- 1988-11-11 JP JP63286603A patent/JPH01153641A/ja active Pending
- 1988-11-11 ES ES198888118871T patent/ES2034117T3/es not_active Expired - Lifetime
- 1988-11-11 AT AT88118871T patent/ATE76576T1/de not_active IP Right Cessation
- 1988-11-11 EP EP88118871A patent/EP0316815B1/en not_active Expired - Lifetime
-
1992
- 1992-08-19 GR GR920401764T patent/GR3005443T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE76576T1 (de) | 1992-06-15 |
| JPH01153641A (ja) | 1989-06-15 |
| DE3871494D1 (de) | 1992-07-02 |
| EP0316815A1 (en) | 1989-05-24 |
| GR3005443T3 (enExample) | 1993-05-24 |
| EP0316815B1 (en) | 1992-05-27 |
| CA1326448C (en) | 1994-01-25 |
| US4868168A (en) | 1989-09-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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