ES2033831T3 - Una composicion a base de hierro y metodo para el tratamiento del cancer. - Google Patents

Una composicion a base de hierro y metodo para el tratamiento del cancer.

Info

Publication number
ES2033831T3
ES2033831T3 ES198787302323T ES87302323T ES2033831T3 ES 2033831 T3 ES2033831 T3 ES 2033831T3 ES 198787302323 T ES198787302323 T ES 198787302323T ES 87302323 T ES87302323 T ES 87302323T ES 2033831 T3 ES2033831 T3 ES 2033831T3
Authority
ES
Spain
Prior art keywords
iron
gamma
linolenic acid
acids
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787302323T
Other languages
English (en)
Inventor
David Frederick Horrobin
Michel Edgar Begin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Efamol Holdings PLC
Original Assignee
Efamol Holdings PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Efamol Holdings PLC filed Critical Efamol Holdings PLC
Application granted granted Critical
Publication of ES2033831T3 publication Critical patent/ES2033831T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

COMPOSICIONES FARMACEUTICAMENTE ACEPTABLES DE UNO O MAS ACIDOS GRASOS ESENCIALES N-6 O N-3, EN PARTICULAR, ACIDO GAMMA-LINOLENICO, ACIDO DIHOMO-GAMMA-LINOLENICO O ACIDO EICOSAPENTAENOICO, Y COMPUESTOS DE HIERRO ASIMILABLE EN UNA FORMA DE UNIDAD DE DOSIS, OPCIONALMENTE CON UN DILUYENTE O VEHICULO, ESTANDO DICHOS ACIDOS PRESENTES COMO TALES O COMO DERIVADOS CONVERTIBLES EN ELLOS DENTRO DEL ORGANISMO, Y SIENDO LAS CANTIDADES DE DICHOS ACIDOS O DERIVADOS DE 1 MG A 100 G (CALCULADOS COMO ACIDO GAMMA-LINOLENICO) Y DE DICHOS COMPUESTOS DE HIERRO DE 0,1 MG A 10 G (CALCULADO COMO HIERRO) O SUBMULTIPLOS DE DICHAS CANTIDADES CONVNIENTES PARA SU ADMINISTRACION DIARIA.
ES198787302323T 1986-03-21 1987-03-18 Una composicion a base de hierro y metodo para el tratamiento del cancer. Expired - Lifetime ES2033831T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868607137A GB8607137D0 (en) 1986-03-21 1986-03-21 Compositions

Publications (1)

Publication Number Publication Date
ES2033831T3 true ES2033831T3 (es) 1993-04-01

Family

ID=10595060

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787302323T Expired - Lifetime ES2033831T3 (es) 1986-03-21 1987-03-18 Una composicion a base de hierro y metodo para el tratamiento del cancer.

Country Status (12)

Country Link
US (1) US5128152A (es)
EP (1) EP0246734B1 (es)
JP (1) JP2574153B2 (es)
AT (1) ATE60508T1 (es)
AU (1) AU595012B2 (es)
CA (1) CA1287297C (es)
DE (1) DE3767763D1 (es)
ES (1) ES2033831T3 (es)
GB (1) GB8607137D0 (es)
GR (1) GR3001473T3 (es)
IE (1) IE59635B1 (es)
ZA (1) ZA871788B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5246726A (en) * 1986-03-21 1993-09-21 Efamol Ltd. Iron-containing composition and method for treatment of cancer
US5665874A (en) * 1989-01-17 1997-09-09 John Hopkins University Cancer related antigen
US5759837A (en) * 1989-01-17 1998-06-02 John Hopkins University Chemotherapy for cancer by inhibiting the fatty acid biosynthetic pathway
US5759791A (en) * 1989-01-17 1998-06-02 The Johns Hopkins University Cancer related antigen
US5264217A (en) * 1990-01-30 1993-11-23 Efamol Holdings Ltd. Method of increasing the total fat content of milk
DE69013139T2 (de) * 1990-03-13 1995-05-18 Riha Mittel zur Vorbeugung, Diagnose und Therapie von rheumatischen, autoimmunen, Haut- und Bindegewebekrankheiten von unbekannter Aetiologie und Verfahren zu seiner Herstellung und Verwendung.
NO168152B (no) * 1990-05-23 1991-10-14 Norsk Hydro As Fiskefor
GB2254556B (en) * 1991-04-11 1995-04-12 Fisons Plc Formulations containing linolenic acid
KR100325766B1 (ko) * 1992-07-24 2002-07-27 더 존스 홉킨스 유니버시티 암치료를위한지방산합성억제제를함유하는약학조성물
US5614551A (en) * 1994-01-24 1997-03-25 The Johns Hopkins University Inhibitors of fatty acid synthesis as antimicrobial agents
DE4419256A1 (de) * 1994-06-01 1995-12-07 Rau Freiherr Von Nagell Helmut Verwendung von intravenös applizierbarem Eisen zur Therapie von Tumorerkrankungen und/oder Infektionskrankheiten
US5981575A (en) * 1996-11-15 1999-11-09 Johns Hopkins University, The Inhibition of fatty acid synthase as a means to reduce adipocyte mass
US7947275B2 (en) 2000-05-10 2011-05-24 Signe Biopharma, Inc. Compositions and methods for demonstrating secretory immune system regulation of steroid hormone responsive cancer cell growth
US20030072812A1 (en) 2001-05-10 2003-04-17 Sirbasku David A Breast cancer eradication program
EP1530720A4 (en) * 2001-11-13 2005-08-31 David A Sirbasku PROGRAM FOR EXPLOITING BREAST CANCER
CA2436650A1 (en) * 2003-08-06 2005-02-06 Naturia Inc. Conjugated linolenic acid (clnatm) compositions: synthesis, purification and uses

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3911117A (en) * 1971-12-20 1975-10-07 Fredrik Ender Raw fish and iron chelated with glutamic or ribonucleic acid in a mink diet
DE2967049D1 (en) * 1978-04-11 1984-07-19 Efamol Ltd Pharmaceutical and dietary composition comprising gamma-linolenic acids
ATE24266T1 (de) * 1982-04-16 1987-01-15 Nestle Sa Lipidhaltige zusammensetzung fuer die orale, enterale oder parenterale ernaehrung.
GB8302708D0 (en) * 1983-02-01 1983-03-02 Efamol Ltd Pharmaceutical and dietary composition
US4526902A (en) * 1983-10-24 1985-07-02 Century Laboratories, Inc. Combined fatty acid composition for treatment or prophylaxis of thrombo-embolic conditions
US4745099A (en) * 1985-02-06 1988-05-17 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition for the treatment of the anemia of malignant tumors

Also Published As

Publication number Publication date
GR3001473T3 (en) 1992-10-08
ATE60508T1 (de) 1991-02-15
EP0246734B1 (en) 1991-01-30
AU7018187A (en) 1987-09-24
JP2574153B2 (ja) 1997-01-22
IE59635B1 (en) 1994-03-09
GB8607137D0 (en) 1986-04-30
EP0246734A1 (en) 1987-11-25
ZA871788B (en) 1987-10-28
AU595012B2 (en) 1990-03-22
US5128152A (en) 1992-07-07
CA1287297C (en) 1991-08-06
IE870638L (en) 1987-09-21
DE3767763D1 (de) 1991-03-07
JPS62226923A (ja) 1987-10-05

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