ES2033577A1 - Prepn. of carboxy-di:methyl-amino-ethyl-methyl-amino-sulphonyl-methyl-indole - Google Patents
Prepn. of carboxy-di:methyl-amino-ethyl-methyl-amino-sulphonyl-methyl-indoleInfo
- Publication number
- ES2033577A1 ES2033577A1 ES919101359A ES9101359A ES2033577A1 ES 2033577 A1 ES2033577 A1 ES 2033577A1 ES 919101359 A ES919101359 A ES 919101359A ES 9101359 A ES9101359 A ES 9101359A ES 2033577 A1 ES2033577 A1 ES 2033577A1
- Authority
- ES
- Spain
- Prior art keywords
- methyl
- amino
- carboxy
- ethyl
- prepn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
Prodn. of 2-carboxy-3-(2-(dimethyl-amino) ethyl-N-methyl-IH-indol-5-methano sulphonamide (I) and its lower alkyl esters comprises reacting cpd. of formula (III) (where ALK is lower alkyl and x is a leaving gp. e.g. halo, mesyl or hosyl) with Me2NH in the presence of a solvent, to give a cpd. of formula (II), which is saponified to give (7).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9101359A ES2033577B1 (en) | 1991-06-06 | 1991-06-06 | PROCEDURE FOR OBTAINING 2-CARBOXY-3- (2- (DIMETHYLAMINE) ETHYL) -N-METHYL-1H-INDOL-5-METHANOSULFONAMIDE AND ITS LOWER ALKYL ESTERS. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9101359A ES2033577B1 (en) | 1991-06-06 | 1991-06-06 | PROCEDURE FOR OBTAINING 2-CARBOXY-3- (2- (DIMETHYLAMINE) ETHYL) -N-METHYL-1H-INDOL-5-METHANOSULFONAMIDE AND ITS LOWER ALKYL ESTERS. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2033577A1 true ES2033577A1 (en) | 1993-03-16 |
ES2033577B1 ES2033577B1 (en) | 1995-01-16 |
Family
ID=8272612
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9101359A Expired - Fee Related ES2033577B1 (en) | 1991-06-06 | 1991-06-06 | PROCEDURE FOR OBTAINING 2-CARBOXY-3- (2- (DIMETHYLAMINE) ETHYL) -N-METHYL-1H-INDOL-5-METHANOSULFONAMIDE AND ITS LOWER ALKYL ESTERS. |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2033577B1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004014877A1 (en) * | 2002-08-07 | 2004-02-19 | Vita Cientifica, S.L. | Process for preparing rizatriptan |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2084560B1 (en) * | 1994-03-09 | 1997-01-16 | Almirall Lab | EL INDOL DERIVATIVES PREPARATION PROCEDURE. |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3472870A (en) * | 1966-08-29 | 1969-10-14 | Mead Johnson & Co | Sulfonamidotryptamines |
GB2081717A (en) * | 1980-08-12 | 1982-02-24 | Glaxo Group Ltd | Hereocyclic compounds |
-
1991
- 1991-06-06 ES ES9101359A patent/ES2033577B1/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3472870A (en) * | 1966-08-29 | 1969-10-14 | Mead Johnson & Co | Sulfonamidotryptamines |
GB2081717A (en) * | 1980-08-12 | 1982-02-24 | Glaxo Group Ltd | Hereocyclic compounds |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004014877A1 (en) * | 2002-08-07 | 2004-02-19 | Vita Cientifica, S.L. | Process for preparing rizatriptan |
US7279581B2 (en) | 2002-08-07 | 2007-10-09 | Inke, S.A. | Process for preparing a pharmaceutically active compound |
Also Published As
Publication number | Publication date |
---|---|
ES2033577B1 (en) | 1995-01-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GC2A | Exploitation certificate registered application with search report |
Effective date: 19970415 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20111209 |