ES2033335T3 - Nuevo procedimiento para la preparacion de derivados de la pristinamicina ii b. - Google Patents

Nuevo procedimiento para la preparacion de derivados de la pristinamicina ii b.

Info

Publication number
ES2033335T3
ES2033335T3 ES198787401587T ES87401587T ES2033335T3 ES 2033335 T3 ES2033335 T3 ES 2033335T3 ES 198787401587 T ES198787401587 T ES 198787401587T ES 87401587 T ES87401587 T ES 87401587T ES 2033335 T3 ES2033335 T3 ES 2033335T3
Authority
ES
Spain
Prior art keywords
alkyl
nitrogen
substituted
chosen
sulphoxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787401587T
Other languages
English (en)
Inventor
Jean-Claude Barriere
Jean-Pierre Bastart
Jean-Marc Paris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Application granted granted Critical
Publication of ES2033335T3 publication Critical patent/ES2033335T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06182—Dipeptides with the first amino acid being heterocyclic and Pristinamycin II; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NUEVO PROCEDIMIENTO DE PREPARACION DE DERIVADOS DE FORMULA (1) EN LA CUAL R REPRESENTA: BIEN UN HETEROCICLO NITROGENADO DE 4 A 7 ESLABONES EVENTUALMENTE SUSTITUIDO POR ALCOHIL. BIEN UN RADICAL ALCOHIL (2 A 4 ESLABONES) SUSTITUIDO POR 1 O 2 FENIL, CICLOALCOHILAMINO O N-ALCOHIL N-CICLOALCOHILAMINO (3 A 6 ESLABONES), ALCOHILAMINO, DIALCOHILAMINO O DIALCOHILCARBOMOILOXI (LAS PARTES DIALCOHILAMINO DE ESTOS 2 ULTIMOS RADICALES PUEDEN FORMAR UN HETEROCICLO DE 4 A 7 ESLABONES EVENTUALEMENTE SUSTITUIDOS POR ALCOHIL) O SUSTITUIDO POR 1 O 2 HETEROCICLOS NITROGENADOS DE 4 A 7, EVENTUALMENTE SUSTITUIDO POR ALCOHIL, UNO AL MENOS DE LOS SUSTITUYENTES AQUI ARRIBA TIENEN UN SUSTITUYENTE NITROGENADO CAPAZ DE FORMAR SALES. BIEN UN RADICAL [METIL-1 PIRROLIDINILO-2 (S)] METIL. TODOS LOS ALCOHILOS SON RECTOS O RAMIFICADOS Y TIENEN (SALVO MENCION ESPECIAL) DE 1 A 10 ATOMOS DE CARBONO, SUS ISOMEROS Y SUS SALES, CONSISTEN EN OXIDAR POR MEDIO DEL MONOSULFATO DE POTASIO UN DERIVADO DE LA PRISTINAMICINA 11 O LA FORMULA (11).
ES198787401587T 1987-07-07 1987-07-07 Nuevo procedimiento para la preparacion de derivados de la pristinamicina ii b. Expired - Lifetime ES2033335T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/070,389 US4775753A (en) 1987-07-07 1987-07-07 New process for the preparation of pristinamycin IIB derivatives

Publications (1)

Publication Number Publication Date
ES2033335T3 true ES2033335T3 (es) 1993-03-16

Family

ID=22095006

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787401587T Expired - Lifetime ES2033335T3 (es) 1987-07-07 1987-07-07 Nuevo procedimiento para la preparacion de derivados de la pristinamicina ii b.

Country Status (9)

Country Link
US (1) US4775753A (es)
EP (1) EP0298177B1 (es)
JP (1) JP2552299B2 (es)
AT (1) ATE74926T1 (es)
AU (1) AU593363B2 (es)
DE (1) DE3778359D1 (es)
ES (1) ES2033335T3 (es)
GR (1) GR3004372T3 (es)
ZA (1) ZA874938B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2664598A1 (fr) * 1990-07-16 1992-01-17 Rhone Poulenc Rorer Sa Procede de preparation de sulfinyl pristinamycine iib.
FR2664600B1 (fr) * 1990-07-16 1994-09-02 Rhone Poulenc Sante Nouveau sel derive de la dialcoylaminoalcoyl-sulfonyl-26 pristinamycine iib.
FR2664599B1 (fr) * 1990-07-16 1993-06-18 Rhone Poulenc Sante Vinylsulfonyl pristinamycine et sa preparation.
US6881680B2 (en) 2002-06-14 2005-04-19 Toyo Tanso Co., Ltd. Low nitrogen concentration carbonaceous material and manufacturing method thereof
US8309765B2 (en) * 2007-05-04 2012-11-13 United Phosphorus Limited Process for manufacture of high purity D-(−)-N,N-diethyl-2-(α-naphthoxy) propionamide
JP2013001582A (ja) * 2011-06-13 2013-01-07 Kansai Coke & Chem Co Ltd 等方性黒鉛材料及びその製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL110087C (es) * 1954-12-20
FR2549065B1 (fr) * 1983-07-13 1985-10-25 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2576022B1 (fr) * 1985-01-11 1987-09-11 Rhone Poulenc Sante Nouveaux derives de la pristinamycine ii b, leur preparation et les compositions pharmaceutiques qui les contiennent
GB8616768D0 (en) * 1986-07-09 1986-08-13 May & Baker Ltd Process

Also Published As

Publication number Publication date
GR3004372T3 (es) 1993-03-31
EP0298177B1 (fr) 1992-04-15
EP0298177A1 (fr) 1989-01-11
JPS6416789A (en) 1989-01-20
JP2552299B2 (ja) 1996-11-06
AU593363B2 (en) 1990-02-08
ZA874938B (en) 1988-01-18
AU7529587A (en) 1989-01-12
US4775753A (en) 1988-10-04
DE3778359D1 (de) 1992-05-21
ATE74926T1 (de) 1992-05-15

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