ES2020145A6 - Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid - Google Patents
Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acidInfo
- Publication number
- ES2020145A6 ES2020145A6 ES9001482A ES9001482A ES2020145A6 ES 2020145 A6 ES2020145 A6 ES 2020145A6 ES 9001482 A ES9001482 A ES 9001482A ES 9001482 A ES9001482 A ES 9001482A ES 2020145 A6 ES2020145 A6 ES 2020145A6
- Authority
- ES
- Spain
- Prior art keywords
- dichlorophenyl
- amino
- esters
- obtaining
- phenylacetoxyacetic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid of general formula I, < IMAGE > where R is alkyl or arylalkyl, based on the reaction of an alkyl haloacetate (XCH2COOR(X=Cl or Br) with a salt of formula II, < IMAGE > (M = Na or K) in the presence of a phase transfer catalyst. These esters are useful for obtaining Aceclofenac, a product which has anti-inflammatory and analgesic activity.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9001482A ES2020145A6 (en) | 1990-05-29 | 1990-05-29 | Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9001482A ES2020145A6 (en) | 1990-05-29 | 1990-05-29 | Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2020145A6 true ES2020145A6 (en) | 1991-07-16 |
Family
ID=8267508
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9001482A Expired - Fee Related ES2020145A6 (en) | 1990-05-29 | 1990-05-29 | Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2020145A6 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2065242A1 (en) * | 1992-12-14 | 1995-02-01 | Lepori Farma Sa | Phenylacetic acid derivatives, procedure for obtaining them, and corresponding use |
WO2005073163A1 (en) * | 2004-01-30 | 2005-08-11 | J.B.Chemicals & Pharmaceuticals Ltd. | A process for the preparation of [2-(2,6-dichloro anilino) phenyl] acetoxy acetic acid |
CN102924313A (en) * | 2012-11-13 | 2013-02-13 | 江苏吉贝尔药业有限公司 | Novel preparation method of benzyl aceclofenac |
CN110305027A (en) * | 2019-06-11 | 2019-10-08 | 宁波斯迈克制药有限公司 | A method of producing the Aceclofenac tert-butyl ester |
-
1990
- 1990-05-29 ES ES9001482A patent/ES2020145A6/en not_active Expired - Fee Related
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2065242A1 (en) * | 1992-12-14 | 1995-02-01 | Lepori Farma Sa | Phenylacetic acid derivatives, procedure for obtaining them, and corresponding use |
WO2005073163A1 (en) * | 2004-01-30 | 2005-08-11 | J.B.Chemicals & Pharmaceuticals Ltd. | A process for the preparation of [2-(2,6-dichloro anilino) phenyl] acetoxy acetic acid |
CN102924313A (en) * | 2012-11-13 | 2013-02-13 | 江苏吉贝尔药业有限公司 | Novel preparation method of benzyl aceclofenac |
CN110305027A (en) * | 2019-06-11 | 2019-10-08 | 宁波斯迈克制药有限公司 | A method of producing the Aceclofenac tert-butyl ester |
CN110305027B (en) * | 2019-06-11 | 2022-07-22 | 宁波斯迈克制药有限公司 | Method for producing aceclofenac tert-butyl ester |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA22896A1 (en) | PROCESS FOR THE PRODUCTION OF N-ARYL- AND N-HETEROARYLUREES FOR USE AS INHIBITORS OF ACYLCOENZYMES TO: CHOLESTEROL-ACYLTRANSFERASE (ACAT). | |
AU1892988A (en) | Hydroxyalkyl-azolyl derivatives | |
ES485098A1 (en) | Dibenzothiepin derivatives and a process for producing the same | |
ES2020145A6 (en) | Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid | |
JPS5551041A (en) | Phenyl-fatty acid derivative | |
GR3035865T3 (en) | Process for preparation of 5-hydroxymethylthiazole | |
DE3270717D1 (en) | N-(2,2,2-trifluoroethyl)-n-alkyl-azolyloxyacetic-acid amides, their preparation and use as herbicides and intermediates for their preparation | |
ES2071873T3 (en) | PROCEDURE FOR THE PREPARATION OF 1-OXA-3,8-DIAZA-4-OXO-ESPIRO (4,5) DEAN COMPOUNDS. | |
ES2020146A6 (en) | Process for obtaining 2-[(2,6-dichlorophenyl)amino]- phenylacetoxyacetic acid | |
GB9316863D0 (en) | Chemical process | |
ES8205219A1 (en) | Hydrouracil compounds. | |
JPS54138533A (en) | Novel choline derivative | |
HU9302786D0 (en) | New thiophene-2-carboxylic acid derivatives and process for preparing them | |
EP0298890A3 (en) | New 2-(p-isobutylphenyl)-propionic acid ester and process for the preparation thereof | |
CA2473422A1 (en) | Preparation of 5-chlorimidazoles | |
JPS5673064A (en) | Isoquinoline derivative | |
JPS54128599A (en) | Pyrrolobenzazepin derivative | |
ES8303344A1 (en) | Phenoxypyridylmethyl esters, process for their preparation and their use in pesticidal compositions. | |
DE59307401D1 (en) | Alpha-aryl-alpha-hydroxy-beta-imidazolinyl propionic acid amides | |
HUT42083A (en) | Herbicides containing azolides of kynolin-8-carbonic acid and process for production of the active substance | |
JPS6445334A (en) | 2-(r)-halogeno-4-phenyl lactic acid derivative and production thereof | |
NO954410D0 (en) | Process and preparation of NG-monoalkyl-L-arginine and related compounds | |
AU1027592A (en) | New salts of 2-(2,6-dichloroanilino)-phenylacetic acid, a process for their preparation and their use for pharmaceutical preparations to be applied locally | |
ES2023585A6 (en) | Process for obtaining aminoprofen | |
ES2046141A1 (en) | Process for obtaining 2-((2,6-dichlorophenyl)amino) phenylacetoxy acetic acid |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1A | Transfer granted | ||
PC1A | Transfer granted | ||
FD1A | Patent lapsed |
Effective date: 20101018 |