ES2020145A6 - Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid - Google Patents

Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid

Info

Publication number
ES2020145A6
ES2020145A6 ES9001482A ES9001482A ES2020145A6 ES 2020145 A6 ES2020145 A6 ES 2020145A6 ES 9001482 A ES9001482 A ES 9001482A ES 9001482 A ES9001482 A ES 9001482A ES 2020145 A6 ES2020145 A6 ES 2020145A6
Authority
ES
Spain
Prior art keywords
dichlorophenyl
amino
esters
obtaining
phenylacetoxyacetic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES9001482A
Other languages
Spanish (es)
Inventor
Marti Antonio Ginebra
Cruz Alba Agusti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prodesfarma SA
Original Assignee
Prodesfarma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8267508&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2020145(A6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Prodesfarma SA filed Critical Prodesfarma SA
Priority to ES9001482A priority Critical patent/ES2020145A6/en
Publication of ES2020145A6 publication Critical patent/ES2020145A6/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid of general formula I, < IMAGE > where R is alkyl or arylalkyl, based on the reaction of an alkyl haloacetate (XCH2COOR(X=Cl or Br) with a salt of formula II, < IMAGE > (M = Na or K) in the presence of a phase transfer catalyst. These esters are useful for obtaining Aceclofenac, a product which has anti-inflammatory and analgesic activity.
ES9001482A 1990-05-29 1990-05-29 Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid Expired - Fee Related ES2020145A6 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9001482A ES2020145A6 (en) 1990-05-29 1990-05-29 Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9001482A ES2020145A6 (en) 1990-05-29 1990-05-29 Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid

Publications (1)

Publication Number Publication Date
ES2020145A6 true ES2020145A6 (en) 1991-07-16

Family

ID=8267508

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9001482A Expired - Fee Related ES2020145A6 (en) 1990-05-29 1990-05-29 Process for obtaining esters of 2-(2,6- dichlorophenyl)amino)phenylacetoxyacetic acid

Country Status (1)

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ES (1) ES2020145A6 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2065242A1 (en) * 1992-12-14 1995-02-01 Lepori Farma Sa Phenylacetic acid derivatives, procedure for obtaining them, and corresponding use
WO2005073163A1 (en) * 2004-01-30 2005-08-11 J.B.Chemicals & Pharmaceuticals Ltd. A process for the preparation of [2-(2,6-dichloro anilino) phenyl] acetoxy acetic acid
CN102924313A (en) * 2012-11-13 2013-02-13 江苏吉贝尔药业有限公司 Novel preparation method of benzyl aceclofenac
CN110305027A (en) * 2019-06-11 2019-10-08 宁波斯迈克制药有限公司 A method of producing the Aceclofenac tert-butyl ester

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2065242A1 (en) * 1992-12-14 1995-02-01 Lepori Farma Sa Phenylacetic acid derivatives, procedure for obtaining them, and corresponding use
WO2005073163A1 (en) * 2004-01-30 2005-08-11 J.B.Chemicals & Pharmaceuticals Ltd. A process for the preparation of [2-(2,6-dichloro anilino) phenyl] acetoxy acetic acid
CN102924313A (en) * 2012-11-13 2013-02-13 江苏吉贝尔药业有限公司 Novel preparation method of benzyl aceclofenac
CN110305027A (en) * 2019-06-11 2019-10-08 宁波斯迈克制药有限公司 A method of producing the Aceclofenac tert-butyl ester
CN110305027B (en) * 2019-06-11 2022-07-22 宁波斯迈克制药有限公司 Method for producing aceclofenac tert-butyl ester

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Legal Events

Date Code Title Description
PC1A Transfer granted
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20101018