ES2011831A6 - Substituted 1,3-dioxolane and 1,3-dioxane derivatives, processes for the production and their use - Google Patents

Substituted 1,3-dioxolane and 1,3-dioxane derivatives, processes for the production and their use

Info

Publication number
ES2011831A6
ES2011831A6 ES8801002A ES8801002A ES2011831A6 ES 2011831 A6 ES2011831 A6 ES 2011831A6 ES 8801002 A ES8801002 A ES 8801002A ES 8801002 A ES8801002 A ES 8801002A ES 2011831 A6 ES2011831 A6 ES 2011831A6
Authority
ES
Spain
Prior art keywords
dioxolane
substituted
processes
production
dioxane derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES8801002A
Other languages
Spanish (es)
Inventor
Jeffrey Nadelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES2011831A6 publication Critical patent/ES2011831A6/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/12Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms

Abstract

Compounds of formula I < IMAGE > where m is 1 or 2 n is 1 or 2 R1is < IMAGE > -Ç(C2H5)3 or adamantyl p is 0 to 4 q is 1 to 4 and R2 is hydrogen, methyl, phenyl or benzyl and the methyl group of the tolyl substituent is in the meta or para position, possess antidiabetic activity.
ES8801002A 1987-04-01 1988-03-30 Substituted 1,3-dioxolane and 1,3-dioxane derivatives, processes for the production and their use Expired - Lifetime ES2011831A6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3411887A 1987-04-01 1987-04-01

Publications (1)

Publication Number Publication Date
ES2011831A6 true ES2011831A6 (en) 1990-02-16

Family

ID=21874422

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8801002A Expired - Lifetime ES2011831A6 (en) 1987-04-01 1988-03-30 Substituted 1,3-dioxolane and 1,3-dioxane derivatives, processes for the production and their use

Country Status (18)

Country Link
JP (1) JPS63277672A (en)
KR (1) KR880012224A (en)
AU (1) AU1400788A (en)
BE (1) BE1000783A3 (en)
DE (1) DE3810874A1 (en)
DK (1) DK179288A (en)
ES (1) ES2011831A6 (en)
FR (1) FR2613226B1 (en)
GB (1) GB2202849A (en)
GR (1) GR880100196A (en)
HU (1) HUT50156A (en)
IL (1) IL85920A0 (en)
IT (1) IT1219895B (en)
LU (1) LU87176A1 (en)
NL (1) NL8800805A (en)
PT (1) PT87127B (en)
SE (1) SE8801166L (en)
ZA (1) ZA882350B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8701961D0 (en) * 1987-01-29 1987-03-04 Unilever Plc Perfumery materials

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3235589A1 (en) * 1982-09-25 1984-03-29 Hoechst Ag, 6230 Frankfurt BENZYL ETHER FROM PHENOL-MANNICH-BASEN, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS, INTERMEDIATE PRODUCTS AND METHOD FOR THE PRODUCTION THEREOF

Also Published As

Publication number Publication date
ZA882350B (en) 1989-12-27
GR880100196A (en) 1989-01-31
HUT50156A (en) 1989-12-28
IL85920A0 (en) 1988-09-30
PT87127A (en) 1988-04-01
NL8800805A (en) 1988-11-01
DK179288A (en) 1988-10-02
SE8801166D0 (en) 1988-03-29
DE3810874A1 (en) 1988-10-20
PT87127B (en) 1992-07-31
JPS63277672A (en) 1988-11-15
KR880012224A (en) 1988-11-26
GB2202849A (en) 1988-10-05
AU1400788A (en) 1988-10-06
BE1000783A3 (en) 1989-04-04
SE8801166L (en) 1988-10-02
FR2613226B1 (en) 1989-09-15
LU87176A1 (en) 1988-11-17
IT1219895B (en) 1990-05-24
GB8807503D0 (en) 1988-05-05
IT8847797A0 (en) 1988-03-30
DK179288D0 (en) 1988-03-30
FR2613226A1 (en) 1988-10-07

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991102