ES2010939A6 - Sintesis enzimatica de derivados del dipeptido tyr-arg (kyotorphin) - Google Patents
Sintesis enzimatica de derivados del dipeptido tyr-arg (kyotorphin)Info
- Publication number
- ES2010939A6 ES2010939A6 ES8901398A ES8901398A ES2010939A6 ES 2010939 A6 ES2010939 A6 ES 2010939A6 ES 8901398 A ES8901398 A ES 8901398A ES 8901398 A ES8901398 A ES 8901398A ES 2010939 A6 ES2010939 A6 ES 2010939A6
- Authority
- ES
- Spain
- Prior art keywords
- tyrosine
- arginine
- deriv
- prepn
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
EN UNA PRIMERA ETAPA SE ESTERIFICA LA TIROSINA Y SE PROTEGE SU GRUPO 01-AMINO Y ADEMAS SE ESTERIFICA Y/O AMIDA LA ARGININA. EN UNA SEGUNDA ETAPA SE HACE REACCIONAR EL DERIVADO DE LA TIROSINA CON EL DE LA ARGININA MEDIANTE QUIMOTERIPSINA YA SEA LIBRE O INMOVILIZADA EN UN MEDIO DE REACCION CONTENIENDO ENTRE 20-60% DEL DEIMETILFORMAMIDA. EN UNA TERCERA ETAPA OPCIONAL SE DESPROTEGE EL DIPEPTIDO, YA SEA POR HIDROGENACION CATALITICA, TRATAMIENTO ACIDO O BASICO O ENZIMATICO, PARA OBTENER LOS DIPEPTIDOS DE FORMULA GENERAL DESCRITA.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES8901398A ES2010939A6 (es) | 1989-04-21 | 1989-04-21 | Sintesis enzimatica de derivados del dipeptido tyr-arg (kyotorphin) |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES8901398A ES2010939A6 (es) | 1989-04-21 | 1989-04-21 | Sintesis enzimatica de derivados del dipeptido tyr-arg (kyotorphin) |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2010939A6 true ES2010939A6 (es) | 1989-12-01 |
Family
ID=8261602
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8901398A Expired ES2010939A6 (es) | 1989-04-21 | 1989-04-21 | Sintesis enzimatica de derivados del dipeptido tyr-arg (kyotorphin) |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES2010939A6 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009123487A1 (en) | 2008-04-01 | 2009-10-08 | Bioalvo - Serviços, Investigação E Desenvolvimento Em Biotecnologia S.A. | Compounds for treating pain |
-
1989
- 1989-04-21 ES ES8901398A patent/ES2010939A6/es not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009123487A1 (en) | 2008-04-01 | 2009-10-08 | Bioalvo - Serviços, Investigação E Desenvolvimento Em Biotecnologia S.A. | Compounds for treating pain |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
SA6 | Expiration date (snapshot 920101) |
Free format text: 2009-04-21 |
|
FD1A | Patent lapsed |
Effective date: 20000922 |