ES2002578A6 - Procedimiento para obtener reactivos diagnosticos - Google Patents

Procedimiento para obtener reactivos diagnosticos

Info

Publication number
ES2002578A6
ES2002578A6 ES8700552A ES8700552A ES2002578A6 ES 2002578 A6 ES2002578 A6 ES 2002578A6 ES 8700552 A ES8700552 A ES 8700552A ES 8700552 A ES8700552 A ES 8700552A ES 2002578 A6 ES2002578 A6 ES 2002578A6
Authority
ES
Spain
Prior art keywords
proteins
preparation
stabilized
diagnostic reagents
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8700552A
Other languages
English (en)
Inventor
Moragas Maria Jose Capdevila
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KNICKERBOCKER LAB
Original Assignee
KNICKERBOCKER LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KNICKERBOCKER LAB filed Critical KNICKERBOCKER LAB
Priority to ES8700552A priority Critical patent/ES2002578A6/es
Priority to EP88500020A priority patent/EP0281493B1/en
Priority to ES88500020T priority patent/ES2026274T3/es
Priority to DE8888500020T priority patent/DE3864702D1/de
Publication of ES2002578A6 publication Critical patent/ES2002578A6/es
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56944Streptococcus

Abstract

EL PROCEDIMIENTO COMPRENDE LA PREPARACION DE UNA SOLUCION DE PROTEINAS Y LA DE UNA SUSPENSION DE UN MATERIAL PARTICULADO, EL CUAL SE SENSIBILIZA POR ADSORCION DE PROTEINAS AL MISMO, QUE PREVIAMENTE HAN SIDO ESTABILIZADAS MEDIANTE UN AGENTE QUIMICO BIFUNCIONAL. LA ETAPA DE SENSIBILIZACION SE EFECTUA CON UN EXCESO DE TALES PROTEINAS ESTABILIZADAS, DE MODO QUE UNA FRACCION DE LAS PROTEINAS NO SON ADSORBIDAS Y PERMANECEN DE MODO ESTABLE EN LA SOLUCION. EL REACTIVO OBTENIDO PERMITE SER USADO PARA EL DIAGNOSTICO DE INFECCIONES EN UN HUMANO O ANIMAL MEDIANTE ENSAYOS POR AGLUTINACION, SUPERANDO INCONVENIENTES TALES COMO EL FENOMENO DE ZONA DE REACTIVOS CONOCIDOS.
ES8700552A 1987-03-02 1987-03-02 Procedimiento para obtener reactivos diagnosticos Expired ES2002578A6 (es)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ES8700552A ES2002578A6 (es) 1987-03-02 1987-03-02 Procedimiento para obtener reactivos diagnosticos
EP88500020A EP0281493B1 (en) 1987-03-02 1988-02-25 A process for the preparation of diagnostic reagents
ES88500020T ES2026274T3 (es) 1987-03-02 1988-02-25 Procedimiento para obtener reactivos diagnosticos.
DE8888500020T DE3864702D1 (de) 1987-03-02 1988-02-25 Verfahren zur herstellung von diagnostischen reagenzien.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES8700552A ES2002578A6 (es) 1987-03-02 1987-03-02 Procedimiento para obtener reactivos diagnosticos

Publications (1)

Publication Number Publication Date
ES2002578A6 true ES2002578A6 (es) 1988-08-16

Family

ID=8249750

Family Applications (2)

Application Number Title Priority Date Filing Date
ES8700552A Expired ES2002578A6 (es) 1987-03-02 1987-03-02 Procedimiento para obtener reactivos diagnosticos
ES88500020T Expired - Lifetime ES2026274T3 (es) 1987-03-02 1988-02-25 Procedimiento para obtener reactivos diagnosticos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES88500020T Expired - Lifetime ES2026274T3 (es) 1987-03-02 1988-02-25 Procedimiento para obtener reactivos diagnosticos.

Country Status (3)

Country Link
EP (1) EP0281493B1 (es)
DE (1) DE3864702D1 (es)
ES (2) ES2002578A6 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0534043A3 (en) * 1991-09-25 1993-05-05 Biokit Sa Novel antistreptolysin-o reagent for use with beckman nephelometer system
AU687033B2 (en) * 1993-09-13 1998-02-19 Ciba Corning Diagnostics Corp. Undercoating of solid phase surfaces and direct coating method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329151A (en) * 1979-08-17 1982-05-11 Icl Scientific Stable diagnostic reagent and method for qualitative determinations of streptococci infections
DE3210080A1 (de) * 1982-03-19 1983-09-22 Behringwerke Ag, 3550 Marburg Anti-streptolysin o-latex-reagenz und verfahren zu seiner herstellung
DE3311889A1 (de) * 1983-03-31 1984-10-11 Byk-Mallinckrodt Chemische Produkte Gmbh, 6057 Dietzenbach Verfahren zur irreversiblen bindung von protein an polystyroloberflaechen unter erhaltung der biologischen aktivitaet, so erhaltene polystyroloberflaechen und ihre verwendung
IT1218348B (it) * 1983-05-13 1990-04-12 Farmaceutico Lofarma S A S Ora Metodo per legare in modo stabile antigenti e allergeni a supporti solidi

Also Published As

Publication number Publication date
DE3864702D1 (de) 1991-10-17
ES2026274T3 (es) 1992-04-16
EP0281493B1 (en) 1991-09-11
EP0281493A1 (en) 1988-09-07

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