ES2001101A6 - A procedure for the preparation of stable crystalline cephalosporinic intermediates (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of stable crystalline cephalosporinic intermediates (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES2001101A6
ES2001101A6 ES8601189A ES8601189A ES2001101A6 ES 2001101 A6 ES2001101 A6 ES 2001101A6 ES 8601189 A ES8601189 A ES 8601189A ES 8601189 A ES8601189 A ES 8601189A ES 2001101 A6 ES2001101 A6 ES 2001101A6
Authority
ES
Spain
Prior art keywords
intermediates
preparation
translation
procedure
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601189A
Other languages
Spanish (es)
Inventor
Steven P Brundidge
Paul R Brodfuehrer
Chet Sapino
Shin Kun Mao
Donald G Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/882,107 external-priority patent/US4714760A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES2001101A6 publication Critical patent/ES2001101A6/en
Expired legal-status Critical Current

Links

Landscapes

  • Cephalosporin Compounds (AREA)
  • Catalysts (AREA)

Abstract

A procedure for the preparation of stable crystalline cephalosporine intermediates of formula where x is hi or hcl and nu and nub are certain nitrogenated heterociclic rings, united through a sulfur atom or an atom of nitrogen of the ring, respectively, which is described are substantially exempt from isomero d2; which includes the reaction of a prior silicated intermediate with an alchanol in the presence of methylene chloride; 1,1,1-trichlorotrifluorethane; or 1,1,2-triclorotrifluorethane and posterior acidulation with hi or hcl to obtain respective sales. The intermediates so obtained are useful for the preparation of large-spectrum cephalosporine antibiotics. (Machine-translation by Google Translate, not legally binding)
ES8601189A 1985-08-20 1986-08-19 A procedure for the preparation of stable crystalline cephalosporinic intermediates (Machine-translation by Google Translate, not legally binding) Expired ES2001101A6 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US76756185A 1985-08-20 1985-08-20
US06/882,107 US4714760A (en) 1985-08-20 1986-07-11 Cephalosporin intermediates
PCT/US1986/001637 WO1987001116A1 (en) 1985-08-20 1986-08-12 Process for preparing cephalosporin intermediates

Publications (1)

Publication Number Publication Date
ES2001101A6 true ES2001101A6 (en) 1988-04-16

Family

ID=27375255

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601189A Expired ES2001101A6 (en) 1985-08-20 1986-08-19 A procedure for the preparation of stable crystalline cephalosporinic intermediates (Machine-translation by Google Translate, not legally binding)

Country Status (5)

Country Link
DE (1) DE3688067T2 (en)
ES (1) ES2001101A6 (en)
GR (1) GR862161B (en)
PT (1) PT83229B (en)
YU (1) YU44792B (en)

Also Published As

Publication number Publication date
GR862161B (en) 1986-12-24
YU44792B (en) 1991-02-28
DE3688067T2 (en) 1993-07-01
YU145986A (en) 1988-02-29
DE3688067D1 (en) 1993-04-22
PT83229A (en) 1986-09-01
PT83229B (en) 1989-05-12

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20060821