ES2000021A4 - (cloro-3 propionil)-2 fluoro-4 fenol, procedimiento para su preparacion y aplicacion para la preparacion de la fluoro-6 cromanoma-4. - Google Patents

(cloro-3 propionil)-2 fluoro-4 fenol, procedimiento para su preparacion y aplicacion para la preparacion de la fluoro-6 cromanoma-4.

Info

Publication number
ES2000021A4
ES2000021A4 ES86402343T ES86402343T ES2000021A4 ES 2000021 A4 ES2000021 A4 ES 2000021A4 ES 86402343 T ES86402343 T ES 86402343T ES 86402343 T ES86402343 T ES 86402343T ES 2000021 A4 ES2000021 A4 ES 2000021A4
Authority
ES
Spain
Prior art keywords
fluoro
preparation
chloro
phenol
propionyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
ES86402343T
Other languages
English (en)
Inventor
Dominique Gibert
Didier Wirth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Isochem SAS
Original Assignee
Isochem SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isochem SAS filed Critical Isochem SAS
Publication of ES2000021A4 publication Critical patent/ES2000021A4/es
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/825—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups all hydroxy groups bound to the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedimiento de preparación de (cloro-3 propionil)-2 fluoro-4 fenol de fórmula general (I) (I) se efectúa una acilación de Friedel y Carfts de uoro-4 fenol de uno de sus éteres mediante cloruto de cloro-3 propionilo o bien se efectúa una reacción de transposición de Fries sobre el cloro-3 propionato de fluoro-4 fenilo.
ES86402343T 1985-10-21 1986-10-20 (cloro-3 propionil)-2 fluoro-4 fenol, procedimiento para su preparacion y aplicacion para la preparacion de la fluoro-6 cromanoma-4. Pending ES2000021A4 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8515564A FR2588860B1 (fr) 1985-10-21 1985-10-21 (chloro-3 propionyl)-2 fluoro-4 phenol, procede pour sa preparation, et application a la preparation de la fluoro-6 chromanone-4

Publications (1)

Publication Number Publication Date
ES2000021A4 true ES2000021A4 (es) 1987-09-16

Family

ID=9324026

Family Applications (1)

Application Number Title Priority Date Filing Date
ES86402343T Pending ES2000021A4 (es) 1985-10-21 1986-10-20 (cloro-3 propionil)-2 fluoro-4 fenol, procedimiento para su preparacion y aplicacion para la preparacion de la fluoro-6 cromanoma-4.

Country Status (3)

Country Link
EP (1) EP0225217A1 (es)
ES (1) ES2000021A4 (es)
FR (1) FR2588860B1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7842693B2 (en) 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
CN102603693A (zh) * 2012-04-18 2012-07-25 苏州莱克施德药业有限公司 色满-4-甲酸乙酯的制备工艺
CN104276936B (zh) * 2013-07-12 2016-12-28 国家纳米科学中心 一种双芘类化合物及其荧光纳米聚集体和应用
CN104447658A (zh) * 2014-12-04 2015-03-25 杭州杜易科技有限公司 一种卤代4-色满酮衍生物的制备方法
WO2022016309A1 (en) * 2020-07-20 2022-01-27 Hangzhou Duyi Technology Co. Ltd. Methods for preparing substituted chromanone derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3784643A (en) * 1970-12-11 1974-01-08 Colgate Palmolive Co Aryloxyalkylguanidines
US4364949A (en) * 1979-12-21 1982-12-21 Ciba-Geigy Corporation Hydroxyphenyl ketones
FI821415L (fi) * 1981-04-27 1982-10-28 Hoechst Roussel Pharma 1-/3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl/-4-hydroxi-4-fenylpiperidiner, foerfarande och mellanprodukter foer deras framstaellning och deras anvaendning som laekemedel

Also Published As

Publication number Publication date
FR2588860B1 (fr) 1988-08-12
FR2588860A1 (fr) 1987-04-24
EP0225217A1 (fr) 1987-06-10

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