ES1144311U - Shoes with therapeutic properties (Machine-translation by Google Translate, not legally binding) - Google Patents

Shoes with therapeutic properties (Machine-translation by Google Translate, not legally binding) Download PDF

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Publication number
ES1144311U
ES1144311U ES201531015U ES201531015U ES1144311U ES 1144311 U ES1144311 U ES 1144311U ES 201531015 U ES201531015 U ES 201531015U ES 201531015 U ES201531015 U ES 201531015U ES 1144311 U ES1144311 U ES 1144311U
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Prior art keywords
microcapsules
footwear
lining
therapeutic properties
extracts
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ES201531015U
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Spanish (es)
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ES1144311Y (en
Inventor
Carlos FERNÁNDEZ GARCÍA
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Cruan SL
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Individual
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Priority to ES201531015U priority Critical patent/ES1144311Y/en
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Publication of ES1144311Y publication Critical patent/ES1144311Y/en
Priority to PCT/ES2016/070641 priority patent/WO2017046432A1/en
Priority to KR2020187000029U priority patent/KR20180001531U/en
Priority to DE202016008606.6U priority patent/DE202016008606U1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • AHUMAN NECESSITIES
    • A43FOOTWEAR
    • A43BCHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
    • A43B23/00Uppers; Boot legs; Stiffeners; Other single parts of footwear
    • A43B23/07Linings therefor
    • AHUMAN NECESSITIES
    • A43FOOTWEAR
    • A43BCHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
    • A43B1/00Footwear characterised by the material
    • A43B1/0045Footwear characterised by the material made at least partially of deodorant means
    • AHUMAN NECESSITIES
    • A43FOOTWEAR
    • A43BCHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
    • A43B23/00Uppers; Boot legs; Stiffeners; Other single parts of footwear
    • A43B23/02Uppers; Boot legs
    • A43B23/0205Uppers; Boot legs characterised by the material
    • AHUMAN NECESSITIES
    • A43FOOTWEAR
    • A43BCHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
    • A43B7/00Footwear with health or hygienic arrangements

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)

Abstract

Footwear with therapeutic properties comprising a shoe constituted externally by a cut (1) attached to a lower sole (2), and internally by a template (3) that covers the inner part of the sole (2) and a lining ( 4) that covers the inner part of the cut (1), characterized in that it incorporates microcapsules (5) containing extracts of beneficial substances for the foot, said microcapsules (5) being incorporated in the lining (4) and being detachable from said lining ( 4) and breakable by frictional forces produced by the user's foot. (Machine-translation by Google Translate, not legally binding)

Description

OBJETO DE LA INVENCIÓN OBJECT OF THE INVENTION

La presente invención, referente a un calzado con propiedades terapéuticas, se encuadra en el campo técnico de las partes constitutivas del calzado, concretamente en el de las guarniciones interiores, así como en el campo de los tratamientos de tejidos. The present invention, referring to footwear with therapeutic properties, falls within the technical field of the constituent parts of the footwear, specifically in that of the interior trimmings, as well as in the field of tissue treatments.

ANTECEDENTES DE LA INVENCIÓN BACKGROUND OF THE INVENTION

De entre las distintas partes constituyentes del calzado, en su forma de zapato cerrado, el forro es una de las que entra en contacto directo con el pie del usuario al recubrir la parte interior del zapato evitando el rozamiento del pie con la cara interna de los materiales que forman la pala y la puntera. Es, por tanto, fundamental para determinar las características de comodidad, adaptabilidad y aislamiento de un zapato, y puede modificarse mediante diversas técnicas para otorgarle funcionalidades beneficiosas adicionales que mejoren dichas propiedades y, por tanto, añadan valor al calzado. Among the different constituent parts of the footwear, in its closed shoe form, the lining is one of those that comes into direct contact with the user's foot when covering the inside of the shoe avoiding the friction of the foot with the inner side of the shoes. materials that form the shovel and the toe. It is, therefore, essential to determine the characteristics of comfort, adaptability and isolation of a shoe, and can be modified by various techniques to give it additional beneficial functionalities that improve these properties and, therefore, add value to footwear.

Son bien conocidas en el estado de la técnica la gran cantidad de propiedades beneficiosas que tienen en general los extractos de algunas sustancias naturales como la citronella, el aloe vera o el eucalipto, de las cuales algunas son particularmente interesantes para el cuidado y el bienestar de los pies, ya que por ejemplo el aceite esencial extraído de la citronella actúa como repelente anti mosquitos, y además reduce la sudoración excesiva; el aloe vera es antiinflamatorio, anti fúngico y regenerativo, y el eucalipto tiene propiedades cicatrizantes y desodorantes. The large amount of beneficial properties that extracts of some natural substances such as citronella, aloe vera or eucalyptus have in general are well known in the state of the art, some of which are particularly interesting for the care and well-being of the feet, since for example the essential oil extracted from citronella acts as an anti-mosquito repellent, and also reduces excessive sweating; Aloe Vera is anti-inflammatory, anti-fungal and regenerative, and eucalyptus has healing and deodorant properties.

Por otro lado, la microencapsulación es una técnica conocida y desarrollada desde mediados del siglo XX, y consiste fundamentalmente en inmovilizar una sustancia, en forma sólida, líquida o gaseosa, dentro de una membrana polimérica semipermeable que la rodea y contiene, y que a la vez permite la liberación controlada de dicha sustancia a velocidades determinadas y bajo condiciones específicas, contribuyendo además a conservar sus propiedades biológicas y físico-químicas al aislarla de las condiciones On the other hand, microencapsulation is a technique known and developed since the mid-twentieth century, and consists essentially of immobilizing a substance, in solid, liquid or gaseous form, within a semipermeable polymeric membrane that surrounds and contains it, and that at the It also allows the controlled release of said substance at certain speeds and under specific conditions, also contributing to preserve its biological and physical-chemical properties by isolating it from the conditions

ambientales exteriores. Algunas de las sustancias más habituales que se someten a microencapsulación son vitaminas, minerales, prebióticos, antioxidantes, enzimas o saborizantes. Esta técnica se emplea fundamentalmente en medicina y en la industria alimentaria, aunque recientemente también se ha extendido su uso en otros sectores como el textil o el cosmético. outdoor environmental Some of the most common substances that undergo microencapsulation are vitamins, minerals, prebiotics, antioxidants, enzymes or flavorings. This technique is mainly used in medicine and in the food industry, although recently its use has also been extended in other sectors such as textiles or cosmetics.

DESCRIPCIÓN DE LA INVENCIÓN DESCRIPTION OF THE INVENTION

La presente invención describe un calzado tipo zapato cerrado al que se otorgan funcionalidades terapéuticas adicionales para el pie del usuario mediante la adición de microcápsulas en el forro interior del zapato, conteniendo dichas microcápsulas extractos de diversas sustancias con conocidas propiedades beneficiosas específicas para el pie, como la citronella, el aloe vera, el eucalipto o la fresa. The present invention describes a closed shoe type footwear which is granted additional therapeutic functionalities for the user's foot by adding microcapsules in the inner lining of the shoe, said microcapsules containing extracts of various substances with known specific beneficial properties for the foot, such as Citronella, aloe vera, eucalyptus or strawberry.

Para ello, se emplea un forro elaborado preferentemente en material textil, concretamente en algodón, por la buena capacidad de absorción que presenta debido a su porosidad. Como paso previo a la colocación del forro durante el proceso de elaboración del zapato, dicho textil se sumerge en una solución acuosa que contiene las microcápsulas, de forma que éstas microcápsulas quedan retenidas en los intersticios situados entre las fibras constituyentes del material textil, que posteriormente se extrae del baño de la solución y se somete a un secado para eliminar el líquido disolvente restante. Se obtiene así un material textil que incluye en su estructura las microcápsulas contenedoras de las sustancias beneficiosas. For this, a lining is preferably made of textile material, specifically cotton, because of the good absorption capacity it presents due to its porosity. As a previous step to the placement of the lining during the shoe manufacturing process, said textile is immersed in an aqueous solution containing the microcapsules, so that these microcapsules are retained in the interstices located between the constituent fibers of the textile material, which subsequently It is removed from the solution bath and subjected to drying to remove the remaining solvent liquid. A textile material is thus obtained that includes in its structure the microcapsules containing the beneficial substances.

Dicho textil se emplea posteriormente como forro, recubriendo el zapato por su parte interior excepto en la zona de la suela, que queda cubierta por una plantilla. Las microcápsulas contenidas en dicho forro se van desprendiendo del textil a lo largo del tiempo por rozamiento con el pie del usuario al caminar, rompiéndose tras el desprendimiento la membrana de la microcápsula que contiene el extracto de la sustancia en cuestión, que queda así liberado y actúa produciendo los efectos beneficiosos buscados. Said textile is subsequently used as a lining, covering the shoe on its inside except in the sole area, which is covered by a template. The microcapsules contained in said lining are detached from the textile over time by friction with the user's foot when walking, the microcapsule membrane containing the extract of the substance in question is broken after detachment, which is thus released and It acts producing the beneficial effects sought.

El aspecto final del calzado así obtenido no difiere del de uno al que se no se le hayan añadido las microcápsulas, ya que no varían ni el grosor del forro ni su textura, por lo que The final appearance of the footwear thus obtained does not differ from that of the one to which the microcapsules have not been added, since neither the thickness of the lining nor its texture vary, so

el usuario final no verá comprometida la comodidad de su calzado. the end user will not be compromised the comfort of their footwear.

Pueden incorporarse microcápsulas que contengan cualquier tipo de sustancia que pueda otorgar propiedades beneficiosas adicionales al zapato, y en un modo de realización preferente las microcápsulas que se añaden contienen o bien aceites esenciales extraídos de la citronella (Citronella), con efectos de repulsión de mosquitos, o bien una combinación de extractos de aloe vera (Aloe vera),y eucalipto (Eucalyptus), cuya acción sinérgica otorga, entre otras, propiedades anti fúngicas, antiinflamatorias, cicatrizantes, y desodorantes, o bien extractos de fresa (Fragaria), con propiedades tonificantes en la piel, y en la regeneración de las células muertas. Microcapsules containing any type of substance that can grant additional beneficial properties to the shoe can be incorporated, and in a preferred embodiment the added microcapsules contain either essential oils extracted from citronella (Citronella), with mosquito repel effects, or a combination of extracts of aloe vera (Aloe vera), and eucalyptus (Eucalyptus), whose synergistic action grants, among others, anti fungal, anti-inflammatory, healing, and deodorant properties, or strawberry extracts (Fragaria), with properties toning in the skin, and in the regeneration of dead cells.

El calzado con propiedades terapéuticas obtenido de la manera descrita aporta una serie de ventajas respecto al actual estado de la técnica, siendo la principal la de poder modificar favorablemente sus propiedades mediante una técnica sencilla y económica como es la adición al forro de microcápsulas que contienen extractos de sustancias naturales beneficiosas para el pie, sin variar el conocido procedimiento de elaboración industrial del calzado. Footwear with therapeutic properties obtained in the described manner provides a series of advantages over the current state of the art, the main one being that it can favorably modify its properties through a simple and economical technique such as the addition to the lining of microcapsules containing extracts of natural substances beneficial to the foot, without changing the well-known process of industrial manufacturing of footwear.

DESCRIPCIÓN DE LOS DIBUJOS DESCRIPTION OF THE DRAWINGS

Para complementar la descripción que se está realizando y con objeto de ayudar a una mejor comprensión de las características de la invención, de acuerdo con un ejemplo preferente de realización práctica de la misma, se acompaña como parte integrante de dicha descripción, un juego de dibujos en donde con carácter ilustrativo y no limitativo, se ha representado lo siguiente: To complement the description that is being made and in order to help a better understanding of the characteristics of the invention, according to a preferred example of practical implementation thereof, a set of drawings is attached as an integral part of said description. where, for illustrative and non-limiting purposes, the following has been represented:

Figura 1.-Muestra una vista en perspectiva de una sección longitudinal del zapato, en el que se aprecian sus principales elementos constituyentes. Figure 1.- Shows a perspective view of a longitudinal section of the shoe, in which its main constituent elements are appreciated.

Figura 2.-Muestra una vista en perspectiva de una pieza del textil constituyente del forro del calzado, con una vista ampliada de una zona del mismo para que se aprecien las microcápsulas incorporadas. Figure 2.- Shows a perspective view of a piece of the textile component of the shoe lining, with an enlarged view of an area thereof so that the incorporated microcapsules are appreciated.

REALIZACIÓN PREFERENTE DE LA INVENCIÓN PREFERRED EMBODIMENT OF THE INVENTION

Seguidamente se proporciona, con ayuda de las figuras 1 y 2 anteriormente referidas, una explicación detallada de un ejemplo de realización preferente del objeto de la presente invención. Next, a detailed explanation of a preferred embodiment of the object of the present invention is provided with the aid of Figures 1 and 2 above.

El calzado con propiedades terapéuticas que se describe incluye todo aquel que tiene forma genérica de zapato cerrado, es decir, aquel que cubre completamente la planta, los dedos, el empeine, el talón y el lateral del pie del usuario. Dicho zapato, tal y como se muestra en la figura 1,comprende básicamente por su parte exterior un corte (1) unido a una suela (2) inferior, mientras que por su parte interior comprende una plantilla (3) que recubre la parte interior de la suela (2) y un forro (4) que recubre la parte interior del corte (1). The footwear with therapeutic properties described includes anyone who has a generic closed shoe shape, that is, one that completely covers the sole, the toes, the instep, the heel and the side of the user's foot. Said shoe, as shown in Figure 1, basically comprises on its outer part a cut (1) attached to a lower sole (2), while on its inner part it comprises a jig (3) that covers the inner part of the sole (2) and a lining (4) that covers the inside of the cut (1).

El forro (4) del zapato, preferentemente realizado en material textil, incluye unas microcápsulas (5) retenidas en los intersticios situados entre las fibras constituyentes de dicho textil, como puede apreciarse en la figura 2. Dichas microcápsulas (5) contienen extractos de diversas sustancias con propiedades beneficiosas para el pie. The lining (4) of the shoe, preferably made of textile material, includes microcapsules (5) retained in the interstices located between the constituent fibers of said textile, as can be seen in Figure 2. Said microcapsules (5) contain extracts of various substances with beneficial properties for the foot.

La elección de material textil como preferente para la realización del forro (4), frente al cuero tratado o tejidos sintéticos, se debe a su buena capacidad de absorción. Esta capacidad de absorción se fundamenta en la porosidad que presenta su estructura interna, ya que las fibras constituyentes del material textil se disponen formando multitud de huecos o intersticios en los que se alojarán las microcápsulas (5). The choice of textile material as preferred for the realization of the lining (4), compared to the treated leather or synthetic fabrics, is due to its good absorption capacity. This absorption capacity is based on the porosity of its internal structure, since the constituent fibers of the textile material are arranged forming a multitude of holes or interstices in which the microcapsules will be housed (5).

La incorporación de las microcápsulas (5) al forro (4) se produce en un paso previo a su unión con la parte externa de la pala, dentro del proceso habitual de fabricación del zapato. Dicha incorporación se produce al sumergir completamente el material textil con el que se realiza posteriormente el forro (4) en una solución acuosa que contiene una concentración determinada de microcápsulas (5), en cuyo interior se encuentra el extracto de la sustancia beneficiosa en cuestión, que es absorbida por dicho material textil quedando las microcápsulas (5) retenidas en los intersticios existentes entre las fibras. Tras la sumersión durante un periodo de tiempo prefijado, se extrae el material textil y se le somete a un secado para eliminar el líquido disolvente restante. The incorporation of the microcapsules (5) to the lining (4) occurs in a step prior to their union with the external part of the paddle, within the usual process of manufacturing the shoe. Said incorporation is produced by completely immersing the textile material with which the lining (4) is subsequently made in an aqueous solution containing a certain concentration of microcapsules (5), inside which is the extract of the beneficial substance in question, which is absorbed by said textile material leaving the microcapsules (5) retained in the interstices between the fibers. After submersion for a predetermined period of time, the textile material is removed and subjected to drying to remove the remaining solvent liquid.

El material textil así obtenido, que contiene en su estructura microcápsulas (5) con The textile material thus obtained, which contains in its structure microcapsules (5) with

extractos de la sustancia beneficiosa que se desea incorporar al zapato, se corta para obtener las dimensiones y la forma necesaria para constituir el forro (4) que recubrirá la parte interna del corte (1) del zapato, al cual se une preferentemente por termofijación. Extracts of the beneficial substance that it is desired to incorporate into the shoe, is cut to obtain the dimensions and the form necessary to constitute the lining (4) that will cover the internal part of the cut (1) of the shoe, to which it is preferably attached by heat setting.

Las microcápsulas (5) se van desprendiendo del forro (4) de forma progresiva debido al rozamiento producido en dicho forro (4) por el pie del usuario al caminar, y una vez desprendidas y debido a ese mismo rozamiento, se produce la rotura de las microcápsulas (5), liberándose así la sustancia contenida en el interior, que podrá entonces producir los efectos beneficiosos buscados. The microcapsules (5) are gradually detached from the liner (4) due to the friction produced in said liner (4) by the user's foot when walking, and once detached and due to that same friction, the breakage of the microcapsules (5), thus releasing the substance contained inside, which may then produce the desired beneficial effects.

En una primera realización preferente, el calzado con propiedades terapéuticas comprende un zapato en cuyo forro (4) van unidas microcápsulas (5) que rodean y contienen aceites esenciales extraídos de la citronella (Citronella). Dichos aceites esenciales, al quedar liberados de la microcápsula (5) por fricción, permiten que la citronella actúe como agente repelente biológico de mosquitos al ahuyentarlos por el olor que desprende, cualidad ampliamente conocida y aprovechada a lo largo del tiempo al incorporar los aceites a velas, parches y vaporizadores. Esta primera realización preferente permite que se obtenga un calzado con propiedades especialmente interesantes para lugares con elevada concentración de mosquitos, o donde dichos insectos actúan como vectores transmisores de enfermedades graves como el dengue o la malaria. In a first preferred embodiment, footwear with therapeutic properties comprises a shoe in whose lining (4) microcapsules (5) are attached that surround and contain essential oils extracted from citronella (Citronella). These essential oils, when released from the microcapsule (5) by friction, allow citronella to act as a biological repellent agent for mosquitoes by driving them away by the smell they give off, a widely known quality and used over time by incorporating oils into candles, patches and vaporizers. This first preferred embodiment allows footwear with especially interesting properties to be obtained for places with a high concentration of mosquitoes, or where said insects act as vectors transmitting serious diseases such as dengue or malaria.

En una segunda realización preferente, el calzado con propiedades terapéuticas comprende un zapato en cuyo forro (4) van unidas microcápsulas (5) que rodean y contienen una combinación de extractos de aloe vera (Aloe vera) y eucalipto (Eucalyptus). Dichos extractos, al quedar liberados de la microcápsula (5) por fricción, actúan sinérgicamente obteniendo propiedades antifúngicas, antiinflamatorias, cicatrizantes, tonificantes y desodorantes. De esta segunda realización preferente se obtiene un calzado con propiedades especialmente interesantes en climas con elevadas temperaturas y humedades, las cuales pueden causar, entre otros, problemas de aparición de hongos, hinchazón de los pies y rozaduras. In a second preferred embodiment, the footwear with therapeutic properties comprises a shoe in whose lining (4) microcapsules (5) are attached that surround and contain a combination of aloe vera (Aloe vera) and eucalyptus (Eucalyptus) extracts. Said extracts, when released from the microcapsule (5) by friction, act synergistically obtaining antifungal, anti-inflammatory, healing, toning and deodorant properties. From this second preferred embodiment, footwear with especially interesting properties is obtained in climates with high temperatures and humidity, which can cause, among others, problems of fungal appearance, swelling of the feet and chafing.

En una tercera realización preferente, el calzado con propiedades terapéuticas comprende un zapato en cuyo forro (4) van unidas microcápsulas (5) que rodean y In a third preferred embodiment, the footwear with therapeutic properties comprises a shoe in whose lining (4) microcapsules (5) are attached that surround and

contienen extractos de fresa (Fragaria), con propiedades tonificantes para la piel, beneficiosas para la regeneración de las células muertas. They contain strawberry extracts (Fragaria), with toning properties for the skin, beneficial for the regeneration of dead cells.

Claims (6)

REIVINDICACIONES 1. Calzado con propiedades terapéuticas que comprende un zapato constituido exteriormente por un corte (1) unido a una suela (2) inferior, e interiormente por una 1. Footwear with therapeutic properties comprising a shoe constituted externally by a cut (1) attached to a lower sole (2), and internally by a 5 plantilla (3) que recubre la parte interior de la suela (2) y un forro (4) que recubre la parte interior del corte (1), caracterizado porque incorpora unas microcápsulas (5) contenedoras de extractos de sustancias beneficiosas para el pie, estando dichas microcápsulas (5) incorporadas al forro (4) y siendo desprendibles de dicho forro (4) y rompibles por fuerzas de rozamiento producidas por el pie del usuario. 5 template (3) that covers the inside of the sole (2) and a lining (4) that covers the inside of the cut (1), characterized in that it incorporates microcapsules (5) containing extracts of beneficial substances for the foot , said microcapsules (5) being incorporated into the liner (4) and being removable from said liner (4) and breakable by frictional forces produced by the user's foot. 2. Calzado con propiedades terapéuticas de acuerdo con la reivindicación 1 caracterizado porque el forro (4) comprende un material textil. 2. Footwear with therapeutic properties according to claim 1 characterized in that the lining (4) comprises a textile material. 3. Calzado con propiedades terapéuticas de acuerdo con la reivindicación 2 15 caracterizado porque el material textil del forro (4) comprende algodón. 3. Footwear with therapeutic properties according to claim 2, characterized in that the textile material of the lining (4) comprises cotton. 4. Calzado con propiedades terapéuticas de acuerdo con la reivindicación 1 caracterizado porque los extractos de sustancias beneficiosas para el pie contenidos dentro de las microcápsulas (5) comprenden aceites esenciales extraídos de Citronella. 4. Footwear with therapeutic properties according to claim 1 characterized in that the extracts of beneficial substances for the foot contained within the microcapsules (5) comprise essential oils extracted from Citronella. 5. Calzado con propiedades terapéuticas de acuerdo con la reivindicación 1 caracterizado porque los extractos de sustancias beneficiosas para el pie contenidos dentro de las microcápsulas (5) comprenden una combinación de extractos de aloe vera, eucalipto y fresa. 5. Footwear with therapeutic properties according to claim 1 characterized in that the extracts of beneficial substances for the foot contained within the microcapsules (5) comprise a combination of aloe vera, eucalyptus and strawberry extracts. 6. Calzado con propiedades terapéuticas de acuerdo con la reivindicación 1 caracterizado porque los extractos de sustancias beneficiosas para el pie contenidos dentro de las microcápsulas (5) comprenden extractos de fresa. 6. Footwear with therapeutic properties according to claim 1 characterized in that the extracts of beneficial substances for the foot contained within the microcapsules (5) comprise strawberry extracts. DIBUJOS DRAWINGS
ES201531015U 2015-09-15 2015-09-15 FOOTWEAR WITH THERAPEUTIC PROPERTIES Expired - Fee Related ES1144311Y (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ES201531015U ES1144311Y (en) 2015-09-15 2015-09-15 FOOTWEAR WITH THERAPEUTIC PROPERTIES
PCT/ES2016/070641 WO2017046432A1 (en) 2015-09-15 2016-09-13 Footwear with therapeutic properties
KR2020187000029U KR20180001531U (en) 2015-09-15 2016-09-13 Footwear with therapeutic properties
DE202016008606.6U DE202016008606U1 (en) 2015-09-15 2016-09-13 Footwear with therapeutic properties

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Application Number Priority Date Filing Date Title
ES201531015U ES1144311Y (en) 2015-09-15 2015-09-15 FOOTWEAR WITH THERAPEUTIC PROPERTIES

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ES1144311Y ES1144311Y (en) 2016-01-11

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KR20180001531U (en) 2018-05-24
ES1144311Y (en) 2016-01-11
DE202016008606U1 (en) 2018-08-30
WO2017046432A1 (en) 2017-03-23

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