EP4777832A1 - Biomarqueurs pour typer un échantillon d'un individu à la recherche d'un carcinome hépatocellulaire - Google Patents

Biomarqueurs pour typer un échantillon d'un individu à la recherche d'un carcinome hépatocellulaire

Info

Publication number
EP4777832A1
EP4777832A1 EP24772432.1A EP24772432A EP4777832A1 EP 4777832 A1 EP4777832 A1 EP 4777832A1 EP 24772432 A EP24772432 A EP 24772432A EP 4777832 A1 EP4777832 A1 EP 4777832A1
Authority
EP
European Patent Office
Prior art keywords
hcc
proteins
pex14
klrg2
individual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24772432.1A
Other languages
German (de)
English (en)
Inventor
Arie Cornelis BREEDVELD
Blandine Jenneke Huguette LE TALLEC
Mark Johannes Adrianus SCHOONDERWOERD
Leon René LOOGMAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Levels Diagnostics Holding BV
Original Assignee
Levels Diagnostics Holding BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Levels Diagnostics Holding BV filed Critical Levels Diagnostics Holding BV
Publication of EP4777832A1 publication Critical patent/EP4777832A1/fr
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne des procédés in vitro de typage d'un échantillon d'un individu à la recherche de la présence d'un carcinome hépatocellulaire (CHC). L'invention concerne en outre des procédés de traitement d'un individu atteint de CHC, qui est typé selon les procédés de l'invention.
EP24772432.1A 2023-09-12 2024-09-12 Biomarqueurs pour typer un échantillon d'un individu à la recherche d'un carcinome hépatocellulaire Pending EP4777832A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23197015 2023-09-12
PCT/NL2024/050499 WO2025058517A1 (fr) 2023-09-12 2024-09-12 Biomarqueurs pour typer un échantillon d'un individu à la recherche d'un carcinome hépatocellulaire

Publications (1)

Publication Number Publication Date
EP4777832A1 true EP4777832A1 (fr) 2026-07-22

Family

ID=88021014

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24772432.1A Pending EP4777832A1 (fr) 2023-09-12 2024-09-12 Biomarqueurs pour typer un échantillon d'un individu à la recherche d'un carcinome hépatocellulaire

Country Status (3)

Country Link
EP (1) EP4777832A1 (fr)
CN (1) CN122206938A (fr)
WO (1) WO2025058517A1 (fr)

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006678A1 (fr) 1989-10-26 1991-05-16 Sri International Sequençage d'adn
US5846719A (en) 1994-10-13 1998-12-08 Lynx Therapeutics, Inc. Oligonucleotide tags for sorting and identification
US5750341A (en) 1995-04-17 1998-05-12 Lynx Therapeutics, Inc. DNA sequencing by parallel oligonucleotide extensions
GB9620209D0 (en) 1996-09-27 1996-11-13 Cemu Bioteknik Ab Method of sequencing DNA
GB9626815D0 (en) 1996-12-23 1997-02-12 Cemu Bioteknik Ab Method of sequencing DNA
US6969488B2 (en) 1998-05-22 2005-11-29 Solexa, Inc. System and apparatus for sequential processing of analytes
US6274320B1 (en) 1999-09-16 2001-08-14 Curagen Corporation Method of sequencing a nucleic acid
US7057026B2 (en) 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
AU2003259350A1 (en) 2002-08-23 2004-03-11 Solexa Limited Modified nucleotides for polynucleotide sequencing
US7414116B2 (en) 2002-08-23 2008-08-19 Illumina Cambridge Limited Labelled nucleotides
SG170802A1 (en) 2006-03-31 2011-05-30 Solexa Inc Systems and devices for sequence by synthesis analysis
US8030013B2 (en) * 2006-04-14 2011-10-04 Mount Sinai School Of Medicine Methods and compositions for the diagnosis for early hepatocellular carcinoma
US20100130374A1 (en) 2006-09-29 2010-05-27 Annuska Maria Glas High-throughput diagnostic testing using arrays
US9487837B2 (en) * 2008-10-06 2016-11-08 Morehouse School Of Medicine Exosome-mediated diagnosis of hepatitis virus infections and diseases
EP3517959B1 (fr) * 2014-01-21 2021-05-05 Morehouse School of Medicine Détection médiée par des exosomes d'infections par l'hépatite c
WO2016093567A1 (fr) * 2014-12-12 2016-06-16 서울대학교산학협력단 Biomarqueur pour le diagnostic de l'hépatome et son utilisation
KR101788414B1 (ko) * 2014-12-12 2017-10-19 서울대학교산학협력단 간암 조기 진단용 바이오마커 및 그 용도
EP4057006A1 (fr) * 2021-03-08 2022-09-14 Universite De Bordeaux Procédé ex vivo pour l'analyse d'un échantillon de tissu à l'aide d'une mise en correspondance de profil protéomique et son utilisation pour le diagnostic, le pronostic de pathologies et pour la prédiction de la réponse aux traitements

Also Published As

Publication number Publication date
CN122206938A (zh) 2026-06-12
WO2025058517A1 (fr) 2025-03-20

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: UNKNOWN

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20260331

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR