EP4731779A2 - Verfahren und zusammensetzungen zur herstellung extrazellulärer vesikelnukleinsäuren zur erhaltung von informationen über räumliche nähe und anwendungen davon - Google Patents
Verfahren und zusammensetzungen zur herstellung extrazellulärer vesikelnukleinsäuren zur erhaltung von informationen über räumliche nähe und anwendungen davonInfo
- Publication number
- EP4731779A2 EP4731779A2 EP24826749.4A EP24826749A EP4731779A2 EP 4731779 A2 EP4731779 A2 EP 4731779A2 EP 24826749 A EP24826749 A EP 24826749A EP 4731779 A2 EP4731779 A2 EP 4731779A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- nucleic acid
- extracellular vesicle
- subject
- proximity
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363509519P | 2023-06-21 | 2023-06-21 | |
| US202363514335P | 2023-07-18 | 2023-07-18 | |
| PCT/US2024/035061 WO2024263946A2 (en) | 2023-06-21 | 2024-06-21 | Methods and compositions for preparing extracellular vesicle nucleic acids that preserve spatial-proximity information and applications thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP4731779A2 true EP4731779A2 (de) | 2026-04-29 |
Family
ID=93936362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP24826749.4A Pending EP4731779A2 (de) | 2023-06-21 | 2024-06-21 | Verfahren und zusammensetzungen zur herstellung extrazellulärer vesikelnukleinsäuren zur erhaltung von informationen über räumliche nähe und anwendungen davon |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP4731779A2 (de) |
| WO (1) | WO2024263946A2 (de) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9434985B2 (en) * | 2008-09-25 | 2016-09-06 | University Of Massachusetts | Methods of identifying interactions between genomic loci |
| US11396676B2 (en) * | 2016-10-21 | 2022-07-26 | Exosome Diagnostics, Inc. | Sequencing and analysis of exosome associated nucleic acids |
-
2024
- 2024-06-21 EP EP24826749.4A patent/EP4731779A2/de active Pending
- 2024-06-21 WO PCT/US2024/035061 patent/WO2024263946A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024263946A3 (en) | 2025-04-24 |
| WO2024263946A2 (en) | 2024-12-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20260109 |
|
| AK | Designated contracting states |
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