EP4712970A2 - Verbindungen zur behandlung erblicher spastischer paraplegie - Google Patents
Verbindungen zur behandlung erblicher spastischer paraplegieInfo
- Publication number
- EP4712970A2 EP4712970A2 EP24811659.2A EP24811659A EP4712970A2 EP 4712970 A2 EP4712970 A2 EP 4712970A2 EP 24811659 A EP24811659 A EP 24811659A EP 4712970 A2 EP4712970 A2 EP 4712970A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- substituted
- compound
- unsubstituted
- alkyl
- certain embodiments
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202363503262P | 2023-05-19 | 2023-05-19 | |
| PCT/US2024/029856 WO2024243015A2 (en) | 2023-05-19 | 2024-05-17 | Compounds for treating hereditary spastic paraplegia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP4712970A2 true EP4712970A2 (de) | 2026-03-25 |
Family
ID=93590499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP24811659.2A Pending EP4712970A2 (de) | 2023-05-19 | 2024-05-17 | Verbindungen zur behandlung erblicher spastischer paraplegie |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP4712970A2 (de) |
| WO (1) | WO2024243015A2 (de) |
-
2024
- 2024-05-17 WO PCT/US2024/029856 patent/WO2024243015A2/en not_active Ceased
- 2024-05-17 EP EP24811659.2A patent/EP4712970A2/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2024243015A2 (en) | 2024-11-28 |
| WO2024243015A3 (en) | 2025-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US12053465B2 (en) | KCC2 expression enhancing compounds and uses thereof | |
| US11236082B2 (en) | EZH2 inhibitors and uses thereof | |
| JP7493304B2 (ja) | Ｅｚｈ２インヒビターおよびそれらの使用 | |
| JP6491202B2 (ja) | サイクリン依存性キナーゼ７（ｃｄｋ７）の多環阻害剤 | |
| US20190192532A1 (en) | Combination therapy of bromodomain inhibitors and checkpoint blockade | |
| US12121521B2 (en) | Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis | |
| US10961216B2 (en) | Small molecule modulators of the androgen receptor | |
| JP2024155911A (ja) | Ｔａｉｒｅファミリーキナーゼインヒビターおよびそれらの使用 | |
| JP2019518006A (ja) | Ｍｙｄ８８変異型疾患における治療標的としてのｈｃｋ | |
| KR20250109229A (ko) | Ripk2 억제제 및 이의 용도 | |
| WO2024233839A1 (en) | Small molecule inhibitors of glutaminase | |
| US20240294957A1 (en) | Enzymatic synthesis of kavalactones and flavokavains | |
| US20170166558A1 (en) | O-glcnac transferase (ogt) inhibitors and uses thereof | |
| WO2024243015A2 (en) | Compounds for treating hereditary spastic paraplegia | |
| US12582644B2 (en) | O-GlcNAc transferase inhibitors and uses thereof | |
| WO2024249763A2 (en) | Prmt5 synthetic lethal inhibitors targeting mtap deleted cancers | |
| WO2023150203A1 (en) | Hdac6 inhibitors and uses thereof | |
| US20250346943A1 (en) | DEGRADER COMPOUNDS OF QSOX1 mRNA | |
| WO2026039516A1 (en) | Glucosylceramide synthase inhibitors and uses thereof | |
| WO2021023609A1 (en) | Combination of a type i protein arginine methyltransferase (type i prmt) inhibitor and a methionine adenosyltransferase ii alpha (mat2a) inhibitor | |
| CN114945572B (zh) | 用于治疗镰状血球贫血症及β-地中海型贫血的HBF药理诱导化合物 | |
| EP4709715A1 (de) | Verminderung der intrinsisch ungeordneten protein-alpha-synuklein-spiegel durch abzielung auf seine strukturierte mrna mit einer ribonuklease-abzielenden chimäre | |
| WO2024238359A2 (en) | Targeting rnas associated with tauopathies with small molecules | |
| CA3101561A1 (en) | Combined therapy with icos binding proteins and argininemethyltransferase inhibitors | |
| WO2024178067A9 (en) | Chimeric degraders of cyclin-dependent kinase 9 and uses thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
|
| PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
| STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
| 17P | Request for examination filed |
Effective date: 20251204 |
|
| AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR |