EP4712911A2 - Bidirektionale schnittstelle mit elektroden in verschiedenen geweben für zusammengesetzte regenerative periphere nervenschnittstelle (c-rpni) - Google Patents

Bidirektionale schnittstelle mit elektroden in verschiedenen geweben für zusammengesetzte regenerative periphere nervenschnittstelle (c-rpni)

Info

Publication number
EP4712911A2
EP4712911A2 EP24808162.2A EP24808162A EP4712911A2 EP 4712911 A2 EP4712911 A2 EP 4712911A2 EP 24808162 A EP24808162 A EP 24808162A EP 4712911 A2 EP4712911 A2 EP 4712911A2
Authority
EP
European Patent Office
Prior art keywords
additional
graft
nerve
processing circuitry
composite tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24808162.2A
Other languages
English (en)
French (fr)
Inventor
Paul S. Cederna
Stephen KEMP
Theodore A. KUNG
Alex VASKOV
Widya ADIDHARMA
Carrie KUBIAK
Shelby SVIENTEK
Cynthia CHESTEK
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan System
Original Assignee
University of Michigan System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Michigan System filed Critical University of Michigan System
Publication of EP4712911A2 publication Critical patent/EP4712911A2/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0031—Implanted circuitry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/296—Bioelectric electrodes therefor specially adapted for particular uses for electromyography [EMG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/389—Electromyography [EMG]
    • A61B5/395—Details of stimulation, e.g. nerve stimulation to elicit EMG response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/686—Permanently implanted devices, e.g. pacemakers, other stimulators, biochips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
    • A61B5/6877—Nerve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/50—Prostheses not implantable in the body
    • A61F2/68—Operating or control means
    • A61F2/70—Operating or control means electrical
    • A61F2/72—Bioelectric control, e.g. myoelectric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36003—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/22—Arrangements of medical sensors with cables or leads; Connectors or couplings specifically adapted for medical sensors
    • A61B2562/225—Connectors or couplings
    • A61B2562/227—Sensors with electrical connectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Physiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Prostheses (AREA)
EP24808162.2A 2023-05-18 2024-05-17 Bidirektionale schnittstelle mit elektroden in verschiedenen geweben für zusammengesetzte regenerative periphere nervenschnittstelle (c-rpni) Pending EP4712911A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363467499P 2023-05-18 2023-05-18
PCT/US2024/029881 WO2024238894A2 (en) 2023-05-18 2024-05-17 Bi-directional interface with electrodes in different tissues for composite regenerative peripheral nerve interface (c-rpni)

Publications (1)

Publication Number Publication Date
EP4712911A2 true EP4712911A2 (de) 2026-03-25

Family

ID=93519778

Family Applications (4)

Application Number Title Priority Date Filing Date
EP24808168.9A Pending EP4712913A2 (de) 2023-05-18 2024-05-17 Muskelmanschette und regenerative periphere hautnervenschnittstelle mit elektroden in muskel und haut
EP24808166.3A Pending EP4712912A2 (de) 2023-05-18 2024-05-17 Zusammengesetzte regenerative periphere manschettennervenschnittstelle (cc-rpni)
EP24808162.2A Pending EP4712911A2 (de) 2023-05-18 2024-05-17 Bidirektionale schnittstelle mit elektroden in verschiedenen geweben für zusammengesetzte regenerative periphere nervenschnittstelle (c-rpni)
EP24808157.2A Pending EP4712910A2 (de) 2023-05-18 2024-05-17 Mehrfacherfassungselektroden für regenerative periphere nervenschnittstelle (rpni)

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP24808168.9A Pending EP4712913A2 (de) 2023-05-18 2024-05-17 Muskelmanschette und regenerative periphere hautnervenschnittstelle mit elektroden in muskel und haut
EP24808166.3A Pending EP4712912A2 (de) 2023-05-18 2024-05-17 Zusammengesetzte regenerative periphere manschettennervenschnittstelle (cc-rpni)

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP24808157.2A Pending EP4712910A2 (de) 2023-05-18 2024-05-17 Mehrfacherfassungselektroden für regenerative periphere nervenschnittstelle (rpni)

Country Status (7)

Country Link
EP (4) EP4712913A2 (de)
KR (4) KR20260018059A (de)
CN (4) CN121398765A (de)
AU (4) AU2024274377A1 (de)
IL (4) IL324726A (de)
TW (4) TWI896423B (de)
WO (4) WO2024238894A2 (de)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006009722A2 (en) * 2004-06-17 2006-01-26 Innersea Technology, Inc. Long term bi-directional axon-electronic communication system
CN101146496B (zh) * 2005-03-23 2012-08-08 奥苏尔公司 用于进行有知觉的感觉反馈的系统
DE102006008501B3 (de) * 2006-02-23 2007-10-25 Albert-Ludwigs-Universität Freiburg Sonde und Verfahren zur Datenübertragung zwischen einem Gehirn und einer Datenverarbeitungsvorrichtung
US20180200514A1 (en) * 2013-05-30 2018-07-19 Neurostim Oab, Inc. Non-invasive nerve stimulation
WO2015061453A1 (en) * 2013-10-22 2015-04-30 Msssachusetts Institute Of Technology Peripheral neural interface via nerve regeneration to distal tissues
US10314725B2 (en) * 2014-11-13 2019-06-11 The Regents Of The University Of Michigan Method for amplifying signals from individual nerve fascicles
EP3544673B1 (de) * 2016-11-28 2021-11-17 Med-El Elektromedizinische Geraete GmbH Atemüberwachungssensor für einen kehlkopfschrittmacher
WO2019008497A1 (en) * 2017-07-04 2019-01-10 Moradi Ali SYSTEM AND METHOD FOR INCREASING DETECTION OF FLUORESCENCE
EP4335490B1 (de) * 2017-11-13 2025-09-10 The Charles Stark Draper Laboratory, Inc. Implantierbare intra- und transkörper-drahtlosnetzwerke für therapien
AU2020322472B2 (en) * 2019-07-31 2023-12-21 Med-El Elektromedizinische Geraete Gmbh Printed tattoo electrode respiration sensor for laryngeal pacemakers
US20240139514A1 (en) * 2021-02-22 2024-05-02 The Trustees Of The University Of Pennsylvania Implantable sensory system

Also Published As

Publication number Publication date
WO2024238894A2 (en) 2024-11-21
WO2024238901A3 (en) 2025-03-13
KR20260017387A (ko) 2026-02-05
WO2024238901A2 (en) 2024-11-21
IL324695A (en) 2026-01-01
CN121398765A (zh) 2026-01-23
TW202545587A (zh) 2025-12-01
AU2024274377A1 (en) 2025-12-04
KR20260017388A (ko) 2026-02-05
WO2024238894A3 (en) 2025-04-03
AU2024272594A1 (en) 2025-12-04
IL324697A (en) 2026-01-01
KR20260018059A (ko) 2026-02-06
TWI896423B (zh) 2025-09-01
AU2024273999A1 (en) 2025-12-04
CN121443247A (zh) 2026-01-30
EP4712913A2 (de) 2026-03-25
TW202545584A (zh) 2025-12-01
TW202545585A (zh) 2025-12-01
CN121419814A (zh) 2026-01-27
AU2024272710A1 (en) 2025-12-04
TWI896426B (zh) 2025-09-01
WO2024238904A3 (en) 2025-03-13
WO2024238889A3 (en) 2025-02-20
TW202545586A (zh) 2025-12-01
EP4712910A2 (de) 2026-03-25
TWI896424B (zh) 2025-09-01
CN121398766A (zh) 2026-01-23
IL324726A (en) 2026-01-01
EP4712912A2 (de) 2026-03-25
WO2024238904A2 (en) 2024-11-21
IL324724A (en) 2026-01-01
KR20260018058A (ko) 2026-02-06
TWI896425B (zh) 2025-09-01
WO2024238889A2 (en) 2024-11-21

Similar Documents

Publication Publication Date Title
US10779963B2 (en) System for amplifying signals from individual nerve fascicles
US10751532B2 (en) Nerve stimulation device for treating or reducing paralysis
US20250169969A1 (en) Systems and methods for controlling a prosthetic based on amplified nerve signals
TWI896424B (zh) 用於控制假體設備的系統及方法
HK40118967A (zh) 用於基於经放大神经信号控制假体的系统和方法
Štrbac et al. Compact electrotactile stimulation and EMG acquisition system with embedded blanking of stimulation artifacts
Kilgore Hand grasp and reach in spinal cord injury

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20251203

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR