EP4694902A2 - Zusammensetzungen und verfahren mit dezellularisierter extrazellulärer matrix - Google Patents

Zusammensetzungen und verfahren mit dezellularisierter extrazellulärer matrix

Info

Publication number
EP4694902A2
EP4694902A2 EP24789505.5A EP24789505A EP4694902A2 EP 4694902 A2 EP4694902 A2 EP 4694902A2 EP 24789505 A EP24789505 A EP 24789505A EP 4694902 A2 EP4694902 A2 EP 4694902A2
Authority
EP
European Patent Office
Prior art keywords
tissue
tsp2
ecm
rna
hydrogels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP24789505.5A
Other languages
English (en)
French (fr)
Inventor
Themis Kyriakides
Zhuoyue CHEN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yale University filed Critical Yale University
Publication of EP4694902A2 publication Critical patent/EP4694902A2/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP24789505.5A 2023-04-12 2024-04-12 Zusammensetzungen und verfahren mit dezellularisierter extrazellulärer matrix Pending EP4694902A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363495745P 2023-04-12 2023-04-12
PCT/US2024/024208 WO2024215984A2 (en) 2023-04-12 2024-04-12 Compositions and methods comprising decellularized extracellular matrix

Publications (1)

Publication Number Publication Date
EP4694902A2 true EP4694902A2 (de) 2026-02-18

Family

ID=93060141

Family Applications (1)

Application Number Title Priority Date Filing Date
EP24789505.5A Pending EP4694902A2 (de) 2023-04-12 2024-04-12 Zusammensetzungen und verfahren mit dezellularisierter extrazellulärer matrix

Country Status (2)

Country Link
EP (1) EP4694902A2 (de)
WO (1) WO2024215984A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119792548B (zh) * 2025-03-13 2025-06-10 四川大学 一种siRNA递送载体在制备用于治疗骨关节炎的药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017189480A1 (en) * 2016-04-27 2017-11-02 Yale University Compositions and methods for grafts modified with a non-thrombogenic and pro-migratory cell-derived extracellular matrix
WO2019083842A1 (en) * 2017-10-23 2019-05-02 Yale University COMPOSITIONS AND METHODS USEFUL IN REGENERATIVE MEDICINE

Also Published As

Publication number Publication date
WO2024215984A2 (en) 2024-10-17
WO2024215984A3 (en) 2025-02-13

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