EP4232149A4 - COMPOUNDS AND METHODS FOR TREATING EYE DISORDERS - Google Patents

COMPOUNDS AND METHODS FOR TREATING EYE DISORDERS Download PDF

Info

Publication number
EP4232149A4
EP4232149A4 EP21882226.0A EP21882226A EP4232149A4 EP 4232149 A4 EP4232149 A4 EP 4232149A4 EP 21882226 A EP21882226 A EP 21882226A EP 4232149 A4 EP4232149 A4 EP 4232149A4
Authority
EP
European Patent Office
Prior art keywords
compounds
treatment
methods
ocular diseases
ocular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21882226.0A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP4232149A2 (en
Inventor
Ian Holmes
Yair Alster
Hila Barash
Charles Bosworth
Omer Rafaeli
Robert M. Burk
Marc GLEESON
Mark Richard Stewart
Jonathan DUNN
Alexander James NICHOLLS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Azura Ophthalmics Ltd
Original Assignee
Azura Ophthalmics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Azura Ophthalmics Ltd filed Critical Azura Ophthalmics Ltd
Publication of EP4232149A2 publication Critical patent/EP4232149A2/en
Publication of EP4232149A4 publication Critical patent/EP4232149A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP21882226.0A 2020-10-21 2021-10-20 COMPOUNDS AND METHODS FOR TREATING EYE DISORDERS Pending EP4232149A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063094793P 2020-10-21 2020-10-21
US202163170988P 2021-04-05 2021-04-05
PCT/IB2021/000707 WO2022084738A2 (en) 2020-10-21 2021-10-20 Compounds and methods for the treatment of ocular disorders

Publications (2)

Publication Number Publication Date
EP4232149A2 EP4232149A2 (en) 2023-08-30
EP4232149A4 true EP4232149A4 (en) 2024-12-11

Family

ID=81291739

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21882226.0A Pending EP4232149A4 (en) 2020-10-21 2021-10-20 COMPOUNDS AND METHODS FOR TREATING EYE DISORDERS

Country Status (8)

Country Link
EP (1) EP4232149A4 (he)
JP (1) JP2023546453A (he)
KR (1) KR20230110515A (he)
AU (1) AU2021363702A1 (he)
CA (1) CA3196145A1 (he)
IL (1) IL302173A (he)
MX (1) MX2023004537A (he)
WO (1) WO2022084738A2 (he)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7700045B2 (ja) 2019-04-18 2025-06-30 アズーラ オフサルミックス エルティーディー． 眼障害を処置するための化合物および方法
US11459351B1 (en) 2021-04-05 2022-10-04 Azura Ophthalmics Ltd. Compounds and methods for the treatment of ocular disorders
WO2024100454A2 (en) * 2022-11-11 2024-05-16 Azura Ophthalmics Ltd. Composition and methods for improving signs and symptoms of ocular disorders

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013003731A2 (en) * 2011-06-29 2013-01-03 Insite Vision Incorporated Methods of treating recurrent meibomian glands disorder and thereby decreasing the frequency of recurrence
WO2018215638A1 (en) * 2017-05-26 2018-11-29 Novaliq Gmbh Pharmaceutical compositions comprising azithromycin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20040849A2 (en) * 2002-02-15 2005-08-31 Synovo Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
CN114007625A (zh) * 2019-04-18 2022-02-01 阿祖拉眼科有限公司 用于治疗眼病的化合物和方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013003731A2 (en) * 2011-06-29 2013-01-03 Insite Vision Incorporated Methods of treating recurrent meibomian glands disorder and thereby decreasing the frequency of recurrence
WO2018215638A1 (en) * 2017-05-26 2018-11-29 Novaliq Gmbh Pharmaceutical compositions comprising azithromycin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
XIAO-MING YAN ET AL: "Emerging treatment options for meibomian gland dysfunction", CLINICAL OPHTHALMOLOGY, 1 September 2013 (2013-09-01), pages 1797, XP055294421, DOI: 10.2147/OPTH.S33182 *

Also Published As

Publication number Publication date
MX2023004537A (es) 2023-06-15
EP4232149A2 (en) 2023-08-30
AU2021363702A9 (en) 2024-02-08
IL302173A (he) 2023-06-01
JP2023546453A (ja) 2023-11-02
WO2022084738A3 (en) 2022-06-30
CA3196145A1 (en) 2022-04-28
AU2021363702A1 (en) 2023-06-15
KR20230110515A (ko) 2023-07-24
WO2022084738A2 (en) 2022-04-28

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