EP4161525A4 - Procédé de préparation d'un comprimé pelliculé comprenant de la linagliptine et de la metformine - Google Patents

Procédé de préparation d'un comprimé pelliculé comprenant de la linagliptine et de la metformine Download PDF

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Publication number
EP4161525A4
EP4161525A4 EP21818094.1A EP21818094A EP4161525A4 EP 4161525 A4 EP4161525 A4 EP 4161525A4 EP 21818094 A EP21818094 A EP 21818094A EP 4161525 A4 EP4161525 A4 EP 4161525A4
Authority
EP
European Patent Office
Prior art keywords
linagliptin
metformin
preparation
film coated
coated tablet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21818094.1A
Other languages
German (de)
English (en)
Other versions
EP4161525A1 (fr
Inventor
Selda SARI
Nur PEHLIVAN AKALIN
Fatih Sunel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanovel Ilac Sanayi ve Ticaret AS
Original Assignee
Sanovel Ilac Sanayi ve Ticaret AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanovel Ilac Sanayi ve Ticaret AS filed Critical Sanovel Ilac Sanayi ve Ticaret AS
Publication of EP4161525A1 publication Critical patent/EP4161525A1/fr
Publication of EP4161525A4 publication Critical patent/EP4161525A4/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
EP21818094.1A 2020-06-03 2021-05-07 Procédé de préparation d'un comprimé pelliculé comprenant de la linagliptine et de la metformine Pending EP4161525A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2020/08542A TR202008542A2 (tr) 2020-06-03 2020-06-03 Li̇nagli̇pti̇n ve metformi̇n i̇çeren fi̇lm kapli tablet hazirlama prosesi̇
PCT/TR2021/050438 WO2021246985A1 (fr) 2020-06-03 2021-05-07 Procédé de préparation d'un comprimé pelliculé comprenant de la linagliptine et de la metformine

Publications (2)

Publication Number Publication Date
EP4161525A1 EP4161525A1 (fr) 2023-04-12
EP4161525A4 true EP4161525A4 (fr) 2024-06-26

Family

ID=78831356

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21818094.1A Pending EP4161525A4 (fr) 2020-06-03 2021-05-07 Procédé de préparation d'un comprimé pelliculé comprenant de la linagliptine et de la metformine

Country Status (4)

Country Link
EP (1) EP4161525A4 (fr)
CA (1) CA3185535A1 (fr)
TR (1) TR202008542A2 (fr)
WO (1) WO2021246985A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116919911A (zh) * 2023-07-20 2023-10-24 北京诺和德美医药技术有限公司 一种糖尿病治疗药物及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014080383A1 (fr) * 2012-11-26 2014-05-30 Ranbaxy Laboratories Limited Composition pharmaceutique d'inhibiteurs de la dipeptidyl-peptidase-iv (dpp-iv) en association avec d'autres antidiabétiques
WO2015110962A1 (fr) * 2014-01-21 2015-07-30 Wockhardt Limited Compositions pharmaceutiques orales solides comprenant une combinaison de doses fixes de metformine et de linagliptine ou de leurs sels
CN104840960A (zh) * 2014-02-14 2015-08-19 广东东阳光药业有限公司 抗糖尿病的药物组合物及其制备方法
KR20190040765A (ko) * 2017-10-11 2019-04-19 (주)휴온스 Dpp-4 억제제를 포함하는 당뇨병 예방 또는 치료용 약제학적 조성물 및 이의 제조 방법

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014080383A1 (fr) * 2012-11-26 2014-05-30 Ranbaxy Laboratories Limited Composition pharmaceutique d'inhibiteurs de la dipeptidyl-peptidase-iv (dpp-iv) en association avec d'autres antidiabétiques
WO2015110962A1 (fr) * 2014-01-21 2015-07-30 Wockhardt Limited Compositions pharmaceutiques orales solides comprenant une combinaison de doses fixes de metformine et de linagliptine ou de leurs sels
CN104840960A (zh) * 2014-02-14 2015-08-19 广东东阳光药业有限公司 抗糖尿病的药物组合物及其制备方法
KR20190040765A (ko) * 2017-10-11 2019-04-19 (주)휴온스 Dpp-4 억제제를 포함하는 당뇨병 예방 또는 치료용 약제학적 조성물 및 이의 제조 방법

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2021246985A1 *

Also Published As

Publication number Publication date
WO2021246985A1 (fr) 2021-12-09
TR202008542A2 (tr) 2021-12-21
EP4161525A1 (fr) 2023-04-12
CA3185535A1 (fr) 2021-12-09

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