EP4098242A4 - Orale zusammensetzung mit synergistischer verbindung von organischen und anorganischen komponenten zur vollständigen erhaltung der mundgesundheit, verfahren zum erhalten derselben und verwendungen - Google Patents
Orale zusammensetzung mit synergistischer verbindung von organischen und anorganischen komponenten zur vollständigen erhaltung der mundgesundheit, verfahren zum erhalten derselben und verwendungen Download PDFInfo
- Publication number
- EP4098242A4 EP4098242A4 EP20916766.7A EP20916766A EP4098242A4 EP 4098242 A4 EP4098242 A4 EP 4098242A4 EP 20916766 A EP20916766 A EP 20916766A EP 4098242 A4 EP4098242 A4 EP 4098242A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- organic
- oral
- inorganic components
- obtaining same
- complete maintenance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000012423 maintenance Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000002195 synergetic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8105—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- A61K8/8111—Homopolymers or copolymers of aliphatic olefines, e.g. polyethylene, polyisobutene; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A61Q11/02—Preparations for deodorising, bleaching or disinfecting dentures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/48—Thickener, Thickening system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/BR2020/050018 WO2021151174A1 (pt) | 2020-01-29 | 2020-01-29 | Composição oral com associação sinérgica de componentes orgânicos e inorgânicos para manutenção completa da saúde bucal, processo de obtenção e usos |
Publications (2)
Publication Number | Publication Date |
---|---|
EP4098242A1 EP4098242A1 (de) | 2022-12-07 |
EP4098242A4 true EP4098242A4 (de) | 2023-11-15 |
Family
ID=77077985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20916766.7A Pending EP4098242A4 (de) | 2020-01-29 | 2020-01-29 | Orale zusammensetzung mit synergistischer verbindung von organischen und anorganischen komponenten zur vollständigen erhaltung der mundgesundheit, verfahren zum erhalten derselben und verwendungen |
Country Status (7)
Country | Link |
---|---|
US (1) | US20230120190A1 (de) |
EP (1) | EP4098242A4 (de) |
JP (1) | JP2023524338A (de) |
CN (1) | CN115052574A (de) |
AU (1) | AU2020426517A1 (de) |
CA (1) | CA3168623A1 (de) |
WO (1) | WO2021151174A1 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117017889B (zh) * | 2023-09-04 | 2024-07-09 | 吉林大学 | 一种用于缓解口干症的组合物 |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080159968A1 (en) * | 2006-12-27 | 2008-07-03 | Fultz William C | Dentifrices comprising biogenic silica materials and calcium carbonate |
US20080159967A1 (en) * | 2006-12-27 | 2008-07-03 | Fultz William C | Dentifrices comprising biogenic silica materials and at least one calcium phosphate |
US20080267891A1 (en) * | 2007-04-30 | 2008-10-30 | Colgate-Palmolive Company | Oral Care Composition To Reduce Or Eliminate Dental Sensitivity |
US20090186090A1 (en) * | 2007-04-30 | 2009-07-23 | Colgate-Palmolive | Oral Care Composition to Reduce or Eliminate Dental Sensitivity |
US20090324516A1 (en) * | 2008-06-27 | 2009-12-31 | Muscle Dave P | Composition and Method for Enhancing Flouride Uptake Using Bioactive Glass |
US20100040563A1 (en) * | 2008-08-15 | 2010-02-18 | John Christian Haught | Solubilization of Cyclohexane-Based Carboxamide Derivatives for Use as Sensates in Consumer Products |
US20100086498A1 (en) * | 2007-11-20 | 2010-04-08 | John Christian Haught | Personal Care Compositions Providing Enhanced Cooling Sensation |
US20120082628A1 (en) * | 2010-10-01 | 2012-04-05 | John Christian Haught | Oral Care Compositions With Improved Flavor |
US8741269B2 (en) * | 2009-04-01 | 2014-06-03 | Colgate-Palmolive Company | Non-aqueous dentifrice composition with bioacceptable and bioactive glass and methods of use and manufacture thereof |
US20170049671A1 (en) * | 2014-04-30 | 2017-02-23 | Colgate-Palmolive Company | Oral Care Composition Containing Silica and Zinc Citrate |
US9682256B2 (en) * | 2006-07-14 | 2017-06-20 | Colgate-Palmolive Company | Methods of making compositions comprising films |
US20190015313A1 (en) * | 2015-12-30 | 2019-01-17 | Colgate-Palmolive Company | Mucin Coated Silica for Bacterial Aggregagion |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3175951A (en) * | 1963-11-08 | 1965-03-30 | Procter & Gamble | Oral compositions for caries prophylaxis |
US5079298A (en) | 1985-06-11 | 1992-01-07 | Sunstar Giken Kabushiki Kaisha | Silicon-containing polymer having comb-shape structure |
US5522893A (en) | 1993-03-12 | 1996-06-04 | American Dental Association Health Foundation | Calcium phosphate hydroxyapatite precursor and methods for making and using the same |
GB2316940A (en) | 1996-08-30 | 1998-03-11 | Queen Mary & Westfield College | Silicon-substituted hydroxyapatite |
US6649147B1 (en) * | 1999-07-02 | 2003-11-18 | The Procter & Gamble Company | Delivery system for oral care compositions comprising organosiloxane resins using a removable backing strip |
JP2007515427A (ja) | 2003-12-19 | 2007-06-14 | ノバミン テクノロジー インコーポレイテッド | 生物活性ガラス含有歯磨剤を用いてプラーク及び/又は歯肉炎を防ぐ又は低減させるための組成物及び方法 |
EA011125B1 (ru) * | 2005-11-25 | 2008-12-30 | Общество С Ограниченной Ответственностью "Вдс" | Лечебно-профилактический состав для ухода за полостью рта |
ATE539759T1 (de) | 2006-12-05 | 2012-01-15 | Unilever Nv | Mundpflegeprodukt |
GB0900269D0 (en) | 2009-01-08 | 2009-02-11 | Univ Aberdeen | Silicate-substituted hydroxyapatite |
GB201010758D0 (en) | 2010-06-25 | 2010-08-11 | Queen Mary & Westfield College | Bioactive glass composition |
EP2409682A1 (de) | 2010-07-19 | 2012-01-25 | Werner E. G. MÜLLER | Hydroxyapatitbindende Nano- und Mikropartikel zur Kariesprophylaxe und zur Reduzierung von Zahnüberempfindlichkeit |
CN103228246A (zh) | 2010-12-07 | 2013-07-31 | 高露洁-棕榄公司 | 含硅酸钙的洁齿剂组合物 |
US9717929B2 (en) | 2010-12-07 | 2017-08-01 | Colgate-Palmolive Company | Dentifrice compositions containing calcium silicate and a basic amino acid |
WO2013052181A2 (en) | 2011-06-17 | 2013-04-11 | Ndsu Research Foundation | Functionalized silicones with polyalkylene oxide side chains |
GB201305774D0 (en) | 2013-03-28 | 2013-05-15 | Queen Mary & Westfield College | Chlorine-containing silicate glasses and glass ceramics |
WO2018033427A1 (en) | 2016-08-19 | 2018-02-22 | Unilever N.V. | Oral care composition |
AU2017382152B2 (en) | 2016-12-21 | 2020-01-30 | Colgate-Palmolive Company | Whitening dentifrice compositions with zinc core shell silica particles |
EP3668477A1 (de) | 2017-08-18 | 2020-06-24 | Unilever N.V. | Mundpflegezusammensetzung |
GB201721001D0 (en) | 2017-12-15 | 2018-01-31 | Glaxosmithkline Consumer Healthcare (Uk) Ip Ltd | Novel Composition |
-
2020
- 2020-01-29 AU AU2020426517A patent/AU2020426517A1/en active Pending
- 2020-01-29 CA CA3168623A patent/CA3168623A1/en active Pending
- 2020-01-29 CN CN202080095085.XA patent/CN115052574A/zh active Pending
- 2020-01-29 WO PCT/BR2020/050018 patent/WO2021151174A1/pt unknown
- 2020-01-29 EP EP20916766.7A patent/EP4098242A4/de active Pending
- 2020-01-29 JP JP2022546029A patent/JP2023524338A/ja active Pending
- 2020-01-29 US US17/759,628 patent/US20230120190A1/en active Pending
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9682256B2 (en) * | 2006-07-14 | 2017-06-20 | Colgate-Palmolive Company | Methods of making compositions comprising films |
US20080159968A1 (en) * | 2006-12-27 | 2008-07-03 | Fultz William C | Dentifrices comprising biogenic silica materials and calcium carbonate |
US20080159967A1 (en) * | 2006-12-27 | 2008-07-03 | Fultz William C | Dentifrices comprising biogenic silica materials and at least one calcium phosphate |
US20080267891A1 (en) * | 2007-04-30 | 2008-10-30 | Colgate-Palmolive Company | Oral Care Composition To Reduce Or Eliminate Dental Sensitivity |
US20090186090A1 (en) * | 2007-04-30 | 2009-07-23 | Colgate-Palmolive | Oral Care Composition to Reduce or Eliminate Dental Sensitivity |
US20100086498A1 (en) * | 2007-11-20 | 2010-04-08 | John Christian Haught | Personal Care Compositions Providing Enhanced Cooling Sensation |
US20090324516A1 (en) * | 2008-06-27 | 2009-12-31 | Muscle Dave P | Composition and Method for Enhancing Flouride Uptake Using Bioactive Glass |
US20100040563A1 (en) * | 2008-08-15 | 2010-02-18 | John Christian Haught | Solubilization of Cyclohexane-Based Carboxamide Derivatives for Use as Sensates in Consumer Products |
US8741269B2 (en) * | 2009-04-01 | 2014-06-03 | Colgate-Palmolive Company | Non-aqueous dentifrice composition with bioacceptable and bioactive glass and methods of use and manufacture thereof |
US20120082628A1 (en) * | 2010-10-01 | 2012-04-05 | John Christian Haught | Oral Care Compositions With Improved Flavor |
US20170049671A1 (en) * | 2014-04-30 | 2017-02-23 | Colgate-Palmolive Company | Oral Care Composition Containing Silica and Zinc Citrate |
US20190015313A1 (en) * | 2015-12-30 | 2019-01-17 | Colgate-Palmolive Company | Mucin Coated Silica for Bacterial Aggregagion |
Also Published As
Publication number | Publication date |
---|---|
WO2021151174A1 (pt) | 2021-08-05 |
AU2020426517A1 (en) | 2022-08-18 |
CA3168623A1 (en) | 2021-08-05 |
US20230120190A1 (en) | 2023-04-20 |
CN115052574A (zh) | 2022-09-13 |
EP4098242A1 (de) | 2022-12-07 |
JP2023524338A (ja) | 2023-06-12 |
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Ipc: A61K 8/73 20060101ALI20231011BHEP Ipc: A61K 8/25 20060101ALI20231011BHEP Ipc: A61K 8/21 20060101ALI20231011BHEP Ipc: A61Q 11/02 20060101ALI20231011BHEP Ipc: A61K 8/69 20060101ALI20231011BHEP Ipc: A61K 8/49 20060101ALI20231011BHEP Ipc: A61K 8/46 20060101ALI20231011BHEP Ipc: A61K 8/44 20060101ALI20231011BHEP Ipc: A61K 8/34 20060101ALI20231011BHEP Ipc: A61Q 11/00 20060101ALI20231011BHEP Ipc: A61K 8/96 20060101ALI20231011BHEP Ipc: A61K 8/64 20060101ALI20231011BHEP Ipc: A61K 8/55 20060101ALI20231011BHEP Ipc: A61K 8/33 20060101ALI20231011BHEP Ipc: A61K 8/24 20060101ALI20231011BHEP Ipc: A61K 8/19 20060101AFI20231011BHEP |