EP4096655A4 - Pharmaceutical composition suitable for vaginal delivery - Google Patents

Pharmaceutical composition suitable for vaginal delivery Download PDF

Info

Publication number
EP4096655A4
EP4096655A4 EP21748063.1A EP21748063A EP4096655A4 EP 4096655 A4 EP4096655 A4 EP 4096655A4 EP 21748063 A EP21748063 A EP 21748063A EP 4096655 A4 EP4096655 A4 EP 4096655A4
Authority
EP
European Patent Office
Prior art keywords
pharmaceutical composition
composition suitable
vaginal delivery
vaginal
delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP21748063.1A
Other languages
German (de)
French (fr)
Other versions
EP4096655A1 (en
Inventor
Gulay YELKEN DEMIREL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exeltis Ilac Sanayii Ve Ticaret AS
Original Assignee
Exeltis Ilac Sanayii Ve Ticaret AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exeltis Ilac Sanayii Ve Ticaret AS filed Critical Exeltis Ilac Sanayii Ve Ticaret AS
Publication of EP4096655A1 publication Critical patent/EP4096655A1/en
Publication of EP4096655A4 publication Critical patent/EP4096655A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
EP21748063.1A 2020-01-31 2021-01-29 Pharmaceutical composition suitable for vaginal delivery Pending EP4096655A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR202001511 2020-01-31
PCT/TR2021/050086 WO2021154188A1 (en) 2020-01-31 2021-01-29 Pharmaceutical composition suitable for vaginal delivery

Publications (2)

Publication Number Publication Date
EP4096655A1 EP4096655A1 (en) 2022-12-07
EP4096655A4 true EP4096655A4 (en) 2024-02-28

Family

ID=77079220

Family Applications (1)

Application Number Title Priority Date Filing Date
EP21748063.1A Pending EP4096655A4 (en) 2020-01-31 2021-01-29 Pharmaceutical composition suitable for vaginal delivery

Country Status (5)

Country Link
EP (1) EP4096655A4 (en)
BR (1) BR112022015112A2 (en)
EC (1) ECSP22067445A (en)
MX (1) MX2022009303A (en)
WO (1) WO2021154188A1 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103690476A (en) * 2014-01-06 2014-04-02 海南海力制药有限公司 Micronized fenticonazole nitrate preparation composition and preparation method thereof
TR201413590A1 (en) * 2014-11-17 2016-06-21 Mi̇na Karaağaç
CN108079098A (en) * 2018-02-28 2018-05-29 翔宇药业股份有限公司 Pharmaceutical preparation of anti-fungal infection and preparation method thereof
CN108210448A (en) * 2018-04-09 2018-06-29 翔宇药业股份有限公司 Fenticonazole nitrate suppository and its application
US20180311214A1 (en) * 2014-12-20 2018-11-01 John Malcolm Hall Gregg Antimicrobial drug synthesis and therapeutic compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0405406D0 (en) * 2004-03-10 2004-04-21 Edko Pazarlama Tanitim Ltd Sti Anti-vaginitis compositions
US20060137684A1 (en) * 2004-12-01 2006-06-29 Celeste Evans Compositions and methods of treating irritation and kit therefor
RU2674765C2 (en) * 2016-10-03 2018-12-13 Михаил Лукич Ткаченко Antifungal composition of eutectic type (options)

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103690476A (en) * 2014-01-06 2014-04-02 海南海力制药有限公司 Micronized fenticonazole nitrate preparation composition and preparation method thereof
TR201413590A1 (en) * 2014-11-17 2016-06-21 Mi̇na Karaağaç
US20180311214A1 (en) * 2014-12-20 2018-11-01 John Malcolm Hall Gregg Antimicrobial drug synthesis and therapeutic compositions
CN108079098A (en) * 2018-02-28 2018-05-29 翔宇药业股份有限公司 Pharmaceutical preparation of anti-fungal infection and preparation method thereof
CN108210448A (en) * 2018-04-09 2018-06-29 翔宇药业股份有限公司 Fenticonazole nitrate suppository and its application

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 201669, Derwent World Patents Index; AN 2016-62491X, XP002810810 *
JONES B M ET AL: "Comparison of the in vitro activities of fenticonazole, other imidazoles, metronidazole, and tetracycline against organisms associated with bacterial vaginosis and skin infections", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, vol. 33, no. 6, 1 June 1989 (1989-06-01), US, pages 970 - 972, XP093117909, ISSN: 0066-4804, DOI: 10.1128/AAC.33.6.970 *
See also references of WO2021154188A1 *

Also Published As

Publication number Publication date
MX2022009303A (en) 2022-09-19
ECSP22067445A (en) 2022-11-30
BR112022015112A2 (en) 2022-09-27
WO2021154188A1 (en) 2021-08-05
EP4096655A1 (en) 2022-12-07

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RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 9/00 20060101ALI20240118BHEP

Ipc: A61K 31/496 20060101ALI20240118BHEP

Ipc: A61K 31/7056 20060101ALI20240118BHEP

Ipc: A61P 15/02 20060101ALI20240118BHEP

Ipc: A61P 31/10 20060101ALI20240118BHEP

Ipc: A61K 45/06 20060101ALI20240118BHEP

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Ipc: A61K 31/4164 20060101ALI20240118BHEP

Ipc: A61K 31/4174 20060101AFI20240118BHEP

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