EP4084801A4 - A novel viscoelastic formulation for osteoarthritis treatment and a production method thereof - Google Patents

A novel viscoelastic formulation for osteoarthritis treatment and a production method thereof

Info

Publication number
EP4084801A4
EP4084801A4 EP20910352.2A EP20910352A EP4084801A4 EP 4084801 A4 EP4084801 A4 EP 4084801A4 EP 20910352 A EP20910352 A EP 20910352A EP 4084801 A4 EP4084801 A4 EP 4084801A4
Authority
EP
European Patent Office
Prior art keywords
production method
osteoarthritis treatment
novel viscoelastic
viscoelastic formulation
formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20910352.2A
Other languages
German (de)
French (fr)
Other versions
EP4084801A1 (en
Inventor
Faruk Oytun
Busra Gizem Kaya
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VSY Biyoteknoloji ve Ilac Sanayi AS
Original Assignee
VSY Biyoteknoloji ve Ilac Sanayi AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VSY Biyoteknoloji ve Ilac Sanayi AS filed Critical VSY Biyoteknoloji ve Ilac Sanayi AS
Publication of EP4084801A1 publication Critical patent/EP4084801A1/en
Publication of EP4084801A4 publication Critical patent/EP4084801A4/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
    • C08J2305/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
EP20910352.2A 2019-12-31 2020-12-31 A novel viscoelastic formulation for osteoarthritis treatment and a production method thereof Pending EP4084801A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2019/22907A TR201922907A2 (en) 2019-12-31 2019-12-31 A NEW VISCOELASTIC FORMULATION FOR THE TREATMENT OF OSTEOARTHRITIS AND ITS MANUFACTURING METHOD
PCT/TR2020/051471 WO2021137837A1 (en) 2019-12-31 2020-12-31 A novel viscoelastic formulation for osteoarthritis treatment and a production method thereof

Publications (2)

Publication Number Publication Date
EP4084801A1 EP4084801A1 (en) 2022-11-09
EP4084801A4 true EP4084801A4 (en) 2024-04-17

Family

ID=76687210

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20910352.2A Pending EP4084801A4 (en) 2019-12-31 2020-12-31 A novel viscoelastic formulation for osteoarthritis treatment and a production method thereof

Country Status (3)

Country Link
EP (1) EP4084801A4 (en)
TR (2) TR201922945A2 (en)
WO (1) WO2021137837A1 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090143331A1 (en) * 2007-11-30 2009-06-04 Dimitrios Stroumpoulis Polysaccharide gel formulation having increased longevity
US20130136780A1 (en) * 2007-11-30 2013-05-30 Allergan, Inc. Crosslinked polysaccharide gel compositions for medical and cosmetic applications
EP3257549A1 (en) * 2015-02-13 2017-12-20 Endo Derma Co., Ltd. Microstructure using cross-linked hyaluronic acid hydrogel, and method for producing same
KR20180035032A (en) * 2016-09-28 2018-04-05 주식회사 파마리서치프로덕트 Injectable composition comprising cross-linked hyaluronic acid
EP3473242A1 (en) * 2016-06-16 2019-04-24 Endo Derma Co., Ltd. Hyaluronic acid microstructure having excellent solubility characteristics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827937A (en) * 1995-07-17 1998-10-27 Q Med Ab Polysaccharide gel composition
ITPD20120098A1 (en) * 2012-03-30 2013-10-01 Fidia Farmaceutici "NEW PHARAMACEUTICAL FORMULATIONS CONTAINING CONDROITIN SULFATE AND DERIVATIVES OF HYALURONIC ACID"
KR101459070B1 (en) * 2013-12-09 2014-11-17 (주) 뉴메딕 Long lasting crosslinked polysaccharide gel formulation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090143331A1 (en) * 2007-11-30 2009-06-04 Dimitrios Stroumpoulis Polysaccharide gel formulation having increased longevity
US20130136780A1 (en) * 2007-11-30 2013-05-30 Allergan, Inc. Crosslinked polysaccharide gel compositions for medical and cosmetic applications
EP3257549A1 (en) * 2015-02-13 2017-12-20 Endo Derma Co., Ltd. Microstructure using cross-linked hyaluronic acid hydrogel, and method for producing same
EP3473242A1 (en) * 2016-06-16 2019-04-24 Endo Derma Co., Ltd. Hyaluronic acid microstructure having excellent solubility characteristics
KR20180035032A (en) * 2016-09-28 2018-04-05 주식회사 파마리서치프로덕트 Injectable composition comprising cross-linked hyaluronic acid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2021137837A1 *

Also Published As

Publication number Publication date
WO2021137837A1 (en) 2021-07-08
TR201922907A2 (en) 2021-07-26
EP4084801A1 (en) 2022-11-09
TR201922945A2 (en) 2021-07-26

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RIC1 Information provided on ipc code assigned before grant

Ipc: A61P 19/02 20060101ALI20240311BHEP

Ipc: A61K 31/737 20060101ALI20240311BHEP

Ipc: A61K 31/728 20060101AFI20240311BHEP