EP4083194A4 - Composition for medium - Google Patents

Composition for medium

Info

Publication number
EP4083194A4
EP4083194A4 EP20894351.4A EP20894351A EP4083194A4 EP 4083194 A4 EP4083194 A4 EP 4083194A4 EP 20894351 A EP20894351 A EP 20894351A EP 4083194 A4 EP4083194 A4 EP 4083194A4
Authority
EP
European Patent Office
Prior art keywords
composition
medium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20894351.4A
Other languages
German (de)
French (fr)
Other versions
EP4083194A1 (en
Inventor
Ping Dai
Yukimasa Takeda
Yoshinori Harada
Junichi Matsumoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyoto Prefectural PUC
Kataoka Corp
Original Assignee
Kyoto Prefectural PUC
Kataoka Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyoto Prefectural PUC, Kataoka Corp filed Critical Kyoto Prefectural PUC
Publication of EP4083194A1 publication Critical patent/EP4083194A1/en
Publication of EP4083194A4 publication Critical patent/EP4083194A4/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/105—Insulin-like growth factors [IGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/375—Thyroid stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/13—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells
    • C12N2506/1307—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from connective tissue cells, from mesenchymal cells from adult fibroblasts

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP20894351.4A 2019-11-25 2020-11-18 Composition for medium Pending EP4083194A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019211991 2019-11-25
PCT/JP2020/042899 WO2021106698A1 (en) 2019-11-25 2020-11-18 Composition for medium

Publications (2)

Publication Number Publication Date
EP4083194A1 EP4083194A1 (en) 2022-11-02
EP4083194A4 true EP4083194A4 (en) 2024-01-03

Family

ID=76129270

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20894351.4A Pending EP4083194A4 (en) 2019-11-25 2020-11-18 Composition for medium

Country Status (5)

Country Link
US (1) US20230082555A1 (en)
EP (1) EP4083194A4 (en)
JP (1) JPWO2021106698A1 (en)
CN (1) CN114729312A (en)
WO (1) WO2021106698A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118215742A (en) 2021-09-21 2024-06-18 株式会社片冈制作所 Screening method using brown adipocytes

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009137613A2 (en) * 2008-05-06 2009-11-12 Joslin Diabetes Center, Inc. Methods and compositions for inducing brown adipogenesis
WO2013137826A1 (en) * 2012-03-12 2013-09-19 National University Of Singapore Generation of brown adipose tissue (bat) from mesenchymal cells
AU2013221474A1 (en) * 2012-02-15 2014-09-25 DePuy Synthes Products, LLC Methods and composition related to brown adipose-like cells
EP2873727A1 (en) * 2012-07-12 2015-05-20 Kyoto Prefectural Public University Corporation Brown fat cells and method for preparing same
WO2017223457A1 (en) * 2016-06-24 2017-12-28 The Brigham And Women's Hospital, Inc. Generation of brown adipose tissue from pluripotent stem cells in vitro
US20190024054A1 (en) * 2015-10-21 2019-01-24 Kyoto Prefectural Public University Corporation Cell preparation method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4990446B2 (en) 2001-05-28 2012-08-01 電気化学工業株式会社 Injection for treatment of arthropathy
US20170191035A1 (en) * 2014-07-10 2017-07-06 The Trustees Of Columbia University In The City Of New York Ex Vivo Browning of Adipose Tissue Therapy for Reversal of Obesity and Type II Diabetes
US20180216070A1 (en) * 2015-07-10 2018-08-02 Etablissement Francais Du Sang Method for obtaining human brown/beige adipocytes
WO2017026462A1 (en) * 2015-08-07 2017-02-16 京都府公立大学法人 Method for preparing brown adipocyte
US11459546B2 (en) * 2016-09-30 2022-10-04 Kyoto Prefectural Public University Corporation Method for producing somatic cell, somatic cell, and composition
CA3085903A1 (en) * 2017-12-29 2019-07-04 Anagenesis Biotechnologies S.A.S. Method for preparing bap or ba cells
CN110592003B (en) * 2019-09-17 2021-06-18 北京大学 Method for inducing human skin fibroblast to differentiate into fat cell in vitro

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009137613A2 (en) * 2008-05-06 2009-11-12 Joslin Diabetes Center, Inc. Methods and compositions for inducing brown adipogenesis
AU2013221474A1 (en) * 2012-02-15 2014-09-25 DePuy Synthes Products, LLC Methods and composition related to brown adipose-like cells
WO2013137826A1 (en) * 2012-03-12 2013-09-19 National University Of Singapore Generation of brown adipose tissue (bat) from mesenchymal cells
EP2873727A1 (en) * 2012-07-12 2015-05-20 Kyoto Prefectural Public University Corporation Brown fat cells and method for preparing same
US20190024054A1 (en) * 2015-10-21 2019-01-24 Kyoto Prefectural Public University Corporation Cell preparation method
WO2017223457A1 (en) * 2016-06-24 2017-12-28 The Brigham And Women's Hospital, Inc. Generation of brown adipose tissue from pluripotent stem cells in vitro

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
See also references of WO2021106698A1 *
TAKEDA YUKIMASA ET AL: "A developed serum-free medium and an optimized chemical cocktail for direct conversion of human dermal fibroblasts into brown adipocytes", SCIENTIFIC REPORTS, vol. 10, no. 1, 28 February 2020 (2020-02-28), XP093093173, Retrieved from the Internet <URL:https://www.nature.com/articles/s41598-020-60769-x> DOI: 10.1038/s41598-020-60769-x *
TAKEDA YUKIMASA ET AL: "Transcriptome analysis reveals brown adipogenic reprogramming in chemical compound-induced brown adipocytes converted from human dermal fibroblasts", SCIENTIFIC REPORTS, vol. 11, no. 1, 3 March 2021 (2021-03-03), XP093100447, Retrieved from the Internet <URL:https://www.nature.com/articles/s41598-021-84611-0> DOI: 10.1038/s41598-021-84611-0 *

Also Published As

Publication number Publication date
CN114729312A (en) 2022-07-08
US20230082555A1 (en) 2023-03-16
EP4083194A1 (en) 2022-11-02
JPWO2021106698A1 (en) 2021-06-03
WO2021106698A1 (en) 2021-06-03

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