EP4054764A1 - Sealed container comprising a device for releasable connection to an enclosure - Google Patents

Sealed container comprising a device for releasable connection to an enclosure

Info

Publication number
EP4054764A1
EP4054764A1 EP20816272.7A EP20816272A EP4054764A1 EP 4054764 A1 EP4054764 A1 EP 4054764A1 EP 20816272 A EP20816272 A EP 20816272A EP 4054764 A1 EP4054764 A1 EP 4054764A1
Authority
EP
European Patent Office
Prior art keywords
sleeve
flexible film
sealed container
outer sleeve
container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20816272.7A
Other languages
German (de)
French (fr)
Inventor
Julien FELIX
Jean-Luc SCHNEIDER
Thierry Girard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ABC Transfer SAS
Original Assignee
ABC Transfer SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ABC Transfer SAS filed Critical ABC Transfer SAS
Publication of EP4054764A1 publication Critical patent/EP4054764A1/en
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00—Enclosures; Chambers
    • B01L1/02—Air-pressure chambers; Air-locks therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D53/00—Sealing or packing elements; Sealings formed by liquid or plastics material
    • B65D53/02—Collars or rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A61B50/36—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments for collecting or disposing of used articles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B50/00—Containers, covers, furniture or holders specially adapted for surgical or diagnostic appliances or instruments, e.g. sterile covers
    • A61B50/30—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments
    • A61B50/36—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments for collecting or disposing of used articles
    • A61B50/362—Containers specially adapted for packaging, protecting, dispensing, collecting or disposing of surgical or diagnostic appliances or instruments for collecting or disposing of used articles for sharps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26—Accessories or devices or components used for biocidal treatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505—Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/56—Labware specially adapted for transferring fluids
    • B01L3/563—Joints or fittings ; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B39/00—Nozzles, funnels or guides for introducing articles or materials into containers or wrappers
    • B65B39/06—Nozzles, funnels or guides for introducing articles or materials into containers or wrappers adapted to support containers or wrappers
    • B65B39/08—Nozzles, funnels or guides for introducing articles or materials into containers or wrappers adapted to support containers or wrappers by means of clamps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B5/00—Packaging individual articles in containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, jars
    • B65B5/04—Packaging single articles
    • B65B5/045—Packaging single articles in bags
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02—Sterilising, e.g. of complete packages
    • B65B55/027—Packaging in aseptic chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B7/00—Closing containers or receptacles after filling
    • B65B7/16—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons
    • B65B7/28—Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/24—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
    • G21F7/00—Shielded cells or rooms
    • G21F7/005—Shielded passages through walls; Locks; Transferring devices between rooms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10—Apparatus features
    • A61L2202/12—Apparatus for isolating biocidal substances from the environment
    • A61L2202/123—Connecting means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/043—Hinged closures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric

Definitions

  • WATERPROOF CONTAINER INCLUDING A DEVICE ALLOWING REMOVABLE CONNECTION TO A SPEAKER
  • the invention relates to the field of containers intended to be connected in a sealed manner to sterile enclosures in order to allow their respective volumes to be placed in communication without contact with said external environment.
  • the invention relates more particularly to a sealed container comprising a flexible film arranged to define an interior volume and a passage opening allowing the interior volume to be placed in communication with the exterior of the film and a sealed connection device arranged to allow the connection of the flexible film to a complementary connection device of a sterile enclosure.
  • the sealed container according to the invention is intended in particular, but not exclusively for the transfer of dangerous products such as certain pharmaceutical, biotechnological, biological, chemical or radioactive products, the transfer of components such as caps, vials, pistons, syringes, etc. ., transfer of environmental control devices such as culture medium carriers, particle counters, etc., transfer of cleaning systems, transfer of liquids, powders, tools, transfer of waste to the 'exterior of the enclosure and / or the transfer of any element necessary for production or maintenance of the production line.
  • dangerous products such as certain pharmaceutical, biotechnological, biological, chemical or radioactive products
  • components such as caps, vials, pistons, syringes, etc. .
  • environmental control devices such as culture medium carriers, particle counters, etc.
  • transfer of cleaning systems transfer of liquids, powders, tools
  • transfer of waste to the 'exterior of the enclosure and / or the transfer of any element necessary for production or maintenance of the production line.
  • connection of a sealed container to a sterile enclosure for the transfer of products, without breaking the connection and the seal is carried out using two connection devices, one equipping the container, the other equipping the enclosure.
  • Each connection device comprises a flange respectively delimiting the passage opening in the interior volume of the container or of the enclosure, each of the passage openings being closed by a door.
  • the flange and the door of the container are able to be connected respectively to the flange and to the door of the enclosure by a bayonet connection and separated from each other under the action of a rotational movement of the flange and associated door of the container with respect to the flange and door of the enclosure on which they are contiguous.
  • the connection device and the flexible film are assembled by welding the film to the flange.
  • the assembly by welding for this type of container has a certain number of drawbacks.
  • the assembly by welding does not ensure optimum sealing and the presence of leakage points cannot be excluded. Likewise, a homogeneous weld at all points on the surface of the film cannot be guaranteed. In addition, since welding intrinsically modifies the materials on which it is made, it may happen that the flexible film undergoes deterioration during the welding operation, which can then generate points of weakness in terms of resistance and sealing. [007] Second, the junction device has the drawback of not being removable and therefore of not being recyclable.
  • the invention aims to remedy these problems by providing a sealed flexible film container connectable to a sterile enclosure having improved mechanical strength and ensuring optimum sealing.
  • Another object of the invention is to provide a sealed flexible film container that can be connected to a sterile enclosure which can be produced simply and quickly, without risk of deterioration of the film and of contamination.
  • Another object of the invention is to provide a waterproof container with a recyclable flexible film.
  • the invention provides a sealed container comprising a flexible film arranged to define an interior volume and a passage opening as well as a sealed connection device arranged to allow the connection of the flexible film to a connection device complementary to a sterile enclosure by ensuring sterile communication between the interior volume of said container and that of the enclosure, the connection device comprising a flange on which the flexible film is fixed, said flange delimiting the opening for passage of the flexible film , the container being remarkable in that the flange is constituted two separate parts, respectively forming an outer sleeve and an inner sleeve, the flexible film being held in engagement between the outer sleeve and the inner sleeve.
  • the invention also provides a sealed container comprising a flexible film arranged to define an interior volume and a passage opening, a door closing off the passage opening and a sealed connection device arranged to allow the connection of the film.
  • flexible to a complementary connection device of a sterile enclosure by ensuring sterile communication between the interior volume of said container and that of the enclosure, the connection device comprising a flange for assembling the door to the flexible film and means of connection to the complementary connection device of the enclosure, said assembly flange delimiting the opening for passage of the flexible film, the container being remarkable in that the assembly flange consists of two separate parts one of the another, respectively forming an outer sleeve and an inner sleeve on which the door is mounted, the flexible film being held in engagement between the outer sleeve and the internal sleeve.
  • the internal sleeve is surrounded in the lower part by the external sleeve and in the upper part by a collar arranged to ensure the connection to the complementary connection device of the enclosure, the collar forming said connection means of the connection device.
  • the container comprises first means for indexing the connecting collar with the internal sleeve.
  • the container comprises second means for indexing the door with the internal sleeve.
  • the outer sleeve is mounted clipped onto the inner sleeve.
  • the outer and inner sleeves are dimensioned relative to each other so as to bring a gadroon formed on the outer sleeve to bear on the inner sleeve.
  • the means of connection to the complementary connection device of the enclosure are formed integrally with the outer sleeve.
  • the container comprises means for clamping the outer sleeve on the inner sleeve arranged to grip the parts of the outer sleeve and of the inner sleeve between which the flexible film is interposed.
  • the container has an annular seal housed in an internal peripheral groove of the outer sleeve, the flexible film extending between the annular seal and the inner sleeve.
  • the internal sleeve has a face provided with a bearing recess located opposite the peripheral groove of the external sleeve.
  • the internal sleeve comprises a notched zone adjacent to the bearing recess arranged to cooperate with a complementary notch provided on the internal face of the external sleeve.
  • the outer sleeve comprises a lower skirt comprising longitudinal slots extending from the lower end edge of the outer sleeve and evenly distributed over the periphery of said sleeve so as to form resilient tongues capable of exerting a clamping force on the inner sleeve.
  • the elastic tongues comprise means of reciprocal association with the tightening means.
  • the connection device comprises a door mounted on the internal sleeve, closing off the passage opening.
  • the flange comprises an annular seal having a substantially L-shaped section housed in a space delimited by the outer sleeve, the inner sleeve and the door.
  • the flexible film and the connection device are made of a bacteriostatic material.
  • FIG. 1 represents a schematic front view of a container according to the invention
  • FIG. 2 represents a view in partial longitudinal section of the container of FIG.
  • FIG. 3 represents a detailed view of the container of FIG. 2;
  • FIG. 4 represents a partial view of the outer sleeve 5 of the connection device of the container of FIG. 2;
  • FIG. 5 represents an exploded view of the connection device of the container of FIG. 1;
  • FIG. 6 shows a perspective view from above of a container connection device according to another exemplary embodiment of the invention;
  • FIG. 7 represents a perspective view from below of the connection device of FIG. 6;
  • FIG. 8 represents a view in axial section of the connection device of FIG. 6;
  • FIG. 9 represents a detail view of FIG. 8;
  • Figure 10 shows a top sectional view along axis XX of the connection device of Figure 9;
  • FIG. 11 represents a detail view of FIG.
  • FIG. 10 Figure 12 shows a sectional view from below along axis XX of the connection device of Figure 9;
  • FIG. 13 represents a detail view of FIG. 12;
  • FIG. 14 represents a top view of the connection device of FIG. 6;
  • FIG. 15 represents a detailed view of FIG. 14.
  • a container 1 according to a first embodiment of the invention.
  • the illustrated container 1 comprises a flexible film 2 arranged to define an interior volume 3 and a passage opening making it possible to put the interior volume 3 in communication with the exterior of the film.
  • the container also comprises a sealed connection device 4 which is arranged to allow connection of the flexible film 2 to a complementary connection device of a sterile enclosure. The connection is made so as to ensure sterile communication between the interior volume 3 of said container 1 and that of the enclosure.
  • connection device 4 comprises a flange on which the flexible film is fixed, said flange delimiting the opening for the passage of the flexible film, and connection means to the complementary connection device of the enclosure.
  • the flange consists of two separate pieces from each other, a first piece forming a so-called outer sleeve 5 and a second piece forming a so-called inner sleeve 6, between which the flexible film extends.
  • connection device 4 further comprises a removable door 7 fixed to the flange so as to close the passage opening.
  • the flange and the door 7 are fixed to each other by means of notches and ears carried respectively by the internal sleeve 6 and the door 7.
  • the flange thus defines an assembly flange of the flexible film. at the door.
  • the internal sleeve 6 comprises a notched zone 64 adjacent to the support recess 61 arranged to cooperate with a complementary notch 54 provided on the internal face 50 of the external sleeve 5.
  • the outer sleeve 5 comprises, according to an advantageous configuration illustrated in Figure 4, a lower skirt 10 comprising longitudinal slots 11 extending from the lower end edge of said sleeve. These longitudinal slots 11 are advantageously evenly distributed over the periphery of said sleeve. They thus define resilient tongues 12 capable of exerting a homogeneous tightening force over the entire outer periphery of the inner sleeve 6 when the outer sleeve 5 is mounted on the inner sleeve 6.
  • the resilient tongues 12 comprise association means. reciprocal with respectively clamping means, described below, and the internal sleeve 6.
  • the means of reciprocal association with the clamping ring consist of a thread 53 and a notch 54.
  • the clamping means are arranged to enclose the parts of the outer sleeve 5 and the inner sleeve 6 between which the film flexible 2 is interposed.
  • the clamping means are in the form of an external clamping ring comprising an internal thread 90 of complementary shape to a thread 53 formed on the external face 52 of the external sleeve 5.
  • the outer sleeve 5 comprises at the upper periphery, an arrangement of ears forming the connection means to the complementary connection device of the enclosure.
  • the container 1 further comprises a first annular seal 8 housed in a peripheral groove 51 formed on the inner face 50 of the outer sleeve 5 and the outer face 60 of the inner sleeve 6.
  • the flexible film 2 is held in engagement between the annular seal 8 and the internal sleeve 6.
  • the internal sleeve 6 has an external face provided with a bearing recess 61 located opposite the peripheral groove 51 of the outer sleeve 5.
  • the annular seal 8 crushes the flexible film 2 at the level of the recess support 61, ensuring improved engagement of the flexible film 2.
  • the container 1 further comprises a second annular seal 13 which is carried by the flange.
  • the annular seal 13 When the door is in the closed position of the passage opening, the annular seal 13 is housed in the space delimited by the outer sleeve 5, the inner sleeve 6 and the door 7.
  • the annular seal 13 has a section of shape combined with the space in which it is housed.
  • the annular seal 13 has an L-shaped section.
  • connection device is assembled by simple clipping of the elements according to the stack illustrated in FIG. 5.
  • the part of the flexible film located on the side of the passage opening, will be arranged so as to be placed between the outer sleeve 5 and the inner sleeve 6. Tightening will be effective by clamping the ring 9 on the outer sleeve 6, causing the tongues 12 to tighten against the sleeve internal 6.
  • the flexible film 2 can be disassembled by unscrewing the clamping ring 9 and unclipping the external sleeve 5 from the internal sleeve 6.
  • the assembly flange of the door 7 to the flexible film 2 consists of an outer sleeve 5 and an inner sleeve 6 on which the door 7 is mounted, the flexible film 2 being held in engagement between these two sleeves.
  • the outer sleeve 5 is mounted on the inner sleeve 6 by clipping.
  • the outer sleeve 5 has an annular groove 15 arranged to engage with a first circumferential fin 20 of complementary shape provided on the outer face of the inner sleeve 6.
  • the outer sleeve 5 further comprises clips 16 cooperating, when said sleeve is clipped onto the inner sleeve 6, with a complementary imprint made on the inner sleeve 6 ( Figure 10 and 11).
  • the clips 16 thus maintain the axial position of the outer sleeve 5 on the inner sleeve 6 on the one hand and maintain the angular position of the outer sleeve 5 on the inner sleeve 6 on the other hand. They thus ensure axial and angular indexing of the outer sleeve 5 on the inner sleeve 6.
  • the sleeve external 5 has an internal peripheral face provided with a circumferential gadroon 14 arranged to define, with the external peripheral face of the internal sleeve 6, a zone of compression of the portion of film 20 engaged between the sleeves (FIGS. 8 and 9).
  • the shape of the outer 5 and inner 6 sleeves are nominally defined so that the gadroon 14 present on the outer sleeve 5 interferes with the inner sleeve 6.
  • the gadroon 16 acts as a seal.
  • the internal annular part 7 comprises a single gadroon 14 located at the lower end of the external sleeve 5 and extending over the entire circumference of the face. internal peripheral of said sleeve. It is of course obvious that several different gadroons can be provided without departing from the scope of the invention.
  • the inner sleeve 6 is provided in the upper part with a collar 30 carrying the connection means 31 to the complementary connection device of the enclosure.
  • the collar 30 thus forms a so-called connecting flange.
  • the collar 30 will hereinafter be referred to as the connection collar or flange.
  • the connecting collar 30 is mounted at the upper end of the internal sleeve 6 by joint clipping with the seal 13 and the door 7 ( Figures 8 and 9).
  • the connection collar 30 comprises a circumferential internal extension 32 dimensioned to engage in force in the cavity of the seal 13. It also advantageously comprises in the lower part an annular recess 33 in which a second circumferential fin 22 of the internal sleeve 6 comes to engage.
  • the container comprises first indexing means 40 of the connecting collar 30 with the internal sleeve 6, illustrated in Figures 12 and 13, and second indexing means 41 of the door 7 with the internal sleeve 6, illustrated in Figures 14 and 15, the first and second indexing means are, in the example illustrated, radial fingers.
  • the clamping ring and the associated seal 8 are no longer necessary to ensure respectively the maintenance of the flexible film 2 and the sealing of the assembly, these functions being jointly provided by the outer sleeve 5 force-mounted on the internal sleeve 6, and the associated gadroon.
  • the flexible film 2 is, advantageously, previously thermoformed on the internal sleeve 6 so as to form a sealed annular contact line on the surface of the internal sleeve 6. The thermoforming will be carried out at the limit of the weld of the flexible film on the internal sleeve 6 in order to ensure satisfactory fixing of the film while preserving its integrity.
  • the production of the contact line is made so as to be located above the gadroon 14 when the outer sleeve 5 is fitted onto the inner sleeve 6.
  • the flexible film 2 is pinched and the force is maintained by the elasticity of the two rings which are deformed under the force associated with the displacement induced by the interference defined between the gadroon 14 and the internal sleeve 6.
  • the internal sleeve 6 comprises an external chamfer 21, of conical shape, produced at the lower end of said sleeve (FIG. 8 and 9) to facilitate the threading and sliding of the flexible film 2 on the internal sleeve 6.
  • the internal sleeve 6 and the door 7 are provided respectively with notches 70 and ears allowing their assembly by clipping.
  • the flexible film 2 and the connection device 4 are advantageously made of a bacteriostatic material.
  • the seals 8 and 13 are made of a silicone material or other materials minimizing the phenomena of persistence. Provision can also be made for the seals to be made of a bacteriostatic material.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Epidemiology (AREA)
  • Packages (AREA)
  • Closures For Containers (AREA)

Abstract

The invention relates to a sealed container (1) comprising a flexible film (2) which is arranged to define an internal space (3) and a through-opening, and a sealed connection device (4) which is arranged to allow the flexible film (2) to be connected to a complementary connection device of a sterile enclosure, while ensuring sterile communication between the internal space (3) of the container (1) and that of the enclosure, the connection device (4) comprising a flange to which the flexible film (2) is attached, the flange delimiting the through-opening of the flexible film (2), characterised in that the flange is constituted by two mutually different pieces forming an external sleeve (5) and an internal sleeve (6), respectively, the flexible film (2) being kept gripped between the external sleeve (5) and the internal sleeve (6).

Description

CONTENEUR ETANCHE COMPRENANT UN DISPOSITIF PERMETTANT UN RACCORDEMENT AMOVIBLE A UNE ENCEINTE WATERPROOF CONTAINER INCLUDING A DEVICE ALLOWING REMOVABLE CONNECTION TO A SPEAKER
DOMAINE TECHNIQUE DE L’INVENTION TECHNICAL FIELD OF THE INVENTION
[001] L’invention concerne le domaine des conteneurs destinés à être raccordés de manière étanche à des enceintes stériles afin de permettre la mise en communication de leurs volumes respectifs sans contact avec ledit milieu extérieur. The invention relates to the field of containers intended to be connected in a sealed manner to sterile enclosures in order to allow their respective volumes to be placed in communication without contact with said external environment.
[002] L’invention concerne plus particulièrement un conteneur étanche comprenant un film souple arrangé pour définir un volume intérieur et une ouverture de passage permettant de mettre en communication le volume intérieur avec l’extérieur du film et un dispositif de connexion étanche arrangé pour permettre la connexion du film souple à un dispositif de connexion complémentaire d’une enceinte stérile. [002] The invention relates more particularly to a sealed container comprising a flexible film arranged to define an interior volume and a passage opening allowing the interior volume to be placed in communication with the exterior of the film and a sealed connection device arranged to allow the connection of the flexible film to a complementary connection device of a sterile enclosure.
[003] Le conteneur étanche selon l’invention est destiné notamment, mais non exclusivement au transfert de produits dangereux comme certains produits pharmaceutiques, biotechnologiques, biologiques, chimiques ou radioactifs, du transfert de composants tels que bouchons, flacons, pistons, seringues, etc., au transfert de dispositifs de contrôle environnementaux tels que des supports de milieu de culture, des compteurs particulaires, etc., du transfert de systèmes de nettoyage, du transfert de liquides, de poudres, d’outils, du transfert de déchets vers l’extérieur de l’enceinte et/ou du transfert de tout élément nécessaire à la production ou à la maintenance de la ligne de production. The sealed container according to the invention is intended in particular, but not exclusively for the transfer of dangerous products such as certain pharmaceutical, biotechnological, biological, chemical or radioactive products, the transfer of components such as caps, vials, pistons, syringes, etc. ., transfer of environmental control devices such as culture medium carriers, particle counters, etc., transfer of cleaning systems, transfer of liquids, powders, tools, transfer of waste to the 'exterior of the enclosure and / or the transfer of any element necessary for production or maintenance of the production line.
ETAT DE LA TECHNIQUE STATE OF THE ART
[004] De manière connu, le raccordement d’un conteneur étanche à une enceinte stérile pour le transfert de produits, sans rupture de la connexion et de l’étanchéité, est réalisé à l’aide de deux dispositifs de connexion, l’un équipant le conteneur, l’autre équipant l’enceinte. Chaque dispositif de connexion comporte une bride délimitant respectivement l’ouverture de passage dans le volume intérieur du conteneur ou de l’enceinte, chacune des ouvertures de passage étant obturées par une porte. La bride et la porte du conteneur sont aptes à être raccordées respectivement à la bride et à la porte de l’enceinte par une liaison à baïonnettes et désolidarisées l’une de l’autre sous l’action d’un mouvement de rotation de la bride et porte associée du conteneur par rapport à la bride et porte de l’enceinte sur lesquelles elles sont accolées. [005] Dans le cas des conteneurs à film souple, le dispositif de connexion et le film souple sont assemblés par soudure du film sur la bride. L’assemblage par soudure pour ce type de conteneur présente cependant un certain nombre d’inconvénients. In known manner, the connection of a sealed container to a sterile enclosure for the transfer of products, without breaking the connection and the seal, is carried out using two connection devices, one equipping the container, the other equipping the enclosure. Each connection device comprises a flange respectively delimiting the passage opening in the interior volume of the container or of the enclosure, each of the passage openings being closed by a door. The flange and the door of the container are able to be connected respectively to the flange and to the door of the enclosure by a bayonet connection and separated from each other under the action of a rotational movement of the flange and associated door of the container with respect to the flange and door of the enclosure on which they are contiguous. In the case of flexible film containers, the connection device and the flexible film are assembled by welding the film to the flange. However, the assembly by welding for this type of container has a certain number of drawbacks.
[006] En premier lieu, l’assemblage par soudure n’assure pas une étanchéité optimale et la présence de points de fuite ne peut être exclue. De même, il ne peut être garanti une soudure homogène en tout point de la surface du film. De plus, la soudure modifiant intrinsèquement les matériaux sur lesquelles elle est réalisée, il peut arriver que le film souple subisse une altération au cours de l’opération de soudage, pouvant alors générer des points de fragilité en termes de résistance et d’étanchéité. [007] En deuxième lieu, le dispositif de jonction présente l’inconvénient de ne pas être démontable et de fait de ne pas être recyclable. [006] First, the assembly by welding does not ensure optimum sealing and the presence of leakage points cannot be excluded. Likewise, a homogeneous weld at all points on the surface of the film cannot be guaranteed. In addition, since welding intrinsically modifies the materials on which it is made, it may happen that the flexible film undergoes deterioration during the welding operation, which can then generate points of weakness in terms of resistance and sealing. [007] Second, the junction device has the drawback of not being removable and therefore of not being recyclable.
[008] En troisième lieu, l’assemblage par soudure impose les matériaux utilisés pour la bride sur laquelle le film est soudé et pour le film lui-même. [008] Third, the assembly by welding imposes the materials used for the flange on which the film is welded and for the film itself.
[009] L’invention vise à remédier à ces problèmes en proposant un conteneur étanche à film souple raccordable à une enceinte stérile ayant une tenue mécanique améliorée et assurant une étanchéité optimale. [009] The invention aims to remedy these problems by providing a sealed flexible film container connectable to a sterile enclosure having improved mechanical strength and ensuring optimum sealing.
[0010] L’invention a également pour objet de proposer un conteneur étanche à film souple raccordable à une enceinte stérile pouvant être réalisé de manière simple et rapide, sans risque de détérioration du film et de contamination. [0011] L’invention a également pour objet de proposer un conteneur étanche à film souple recyclable. [0010] Another object of the invention is to provide a sealed flexible film container that can be connected to a sterile enclosure which can be produced simply and quickly, without risk of deterioration of the film and of contamination. [0011] Another object of the invention is to provide a waterproof container with a recyclable flexible film.
OBJET DE L’INVENTION OBJECT OF THE INVENTION
[0012] A cet effet, l’invention propose un conteneur étanche comprenant un film souple arrangé pour définir un volume intérieur et une ouverture de passage ainsi qu’un dispositif de connexion étanche arrangé pour permettre la connexion du film souple à un dispositif de connexion complémentaire d’une enceinte stérile en assurant une communication stérile entre le volume intérieur dudit conteneur et celui de l’enceinte, le dispositif de connexion comprenant une bride sur laquelle le film souple est fixé, ladite bride délimitant l’ouverture de passage du film souple, le conteneur étant remarquable en ce que la bride est constituée de deux pièces distinctes l’une de l’autre, formant respectivement un manchon externe et un manchon interne, le film souple étant maintenu en prise entre le manchon externe et le manchon interne. To this end, the invention provides a sealed container comprising a flexible film arranged to define an interior volume and a passage opening as well as a sealed connection device arranged to allow the connection of the flexible film to a connection device complementary to a sterile enclosure by ensuring sterile communication between the interior volume of said container and that of the enclosure, the connection device comprising a flange on which the flexible film is fixed, said flange delimiting the opening for passage of the flexible film , the container being remarkable in that the flange is constituted two separate parts, respectively forming an outer sleeve and an inner sleeve, the flexible film being held in engagement between the outer sleeve and the inner sleeve.
[0013] L’invention propose également un conteneur étanche comprenant un film souple arrangé pour définir un volume intérieur et une ouverture de passage, une porte obturant l’ouverture de passage ainsi qu’un dispositif de connexion étanche arrangé pour permettre la connexion du film souple à un dispositif de connexion complémentaire d’une enceinte stérile en assurant une communication stérile entre le volume intérieur dudit conteneur et celui de l’enceinte, le dispositif de connexion comprenant une bride d’assemblage de la porte au film souple et des moyens de raccordement au dispositif de connexion complémentaire de l’enceinte, ladite bride d’assemblage délimitant l’ouverture de passage du film souple, le conteneur étant remarquable en ce que la bride d’assemblage est constituée de deux pièces distinctes l’une de l’autre, formant respectivement un manchon externe et un manchon interne sur lequel la porte est montée, le film souple étant maintenu en prise entre le manchon externe et le manchon interne. The invention also provides a sealed container comprising a flexible film arranged to define an interior volume and a passage opening, a door closing off the passage opening and a sealed connection device arranged to allow the connection of the film. flexible to a complementary connection device of a sterile enclosure by ensuring sterile communication between the interior volume of said container and that of the enclosure, the connection device comprising a flange for assembling the door to the flexible film and means of connection to the complementary connection device of the enclosure, said assembly flange delimiting the opening for passage of the flexible film, the container being remarkable in that the assembly flange consists of two separate parts one of the another, respectively forming an outer sleeve and an inner sleeve on which the door is mounted, the flexible film being held in engagement between the outer sleeve and the internal sleeve.
[0014] Selon d’autres caractéristiques avantageuses et non limitatives de l’invention, prises seules ou selon toute combinaison techniquement réalisable : le manchon interne est ceinturé en partie inférieure par le manchon externe et en partie supérieure par un collier arrangé pour assurer le raccordement au dispositif de connexion complémentaire de l’enceinte, le collier formant lesdits moyens de raccordement du dispositif de connexion. le conteneur comporte des premiers moyens d’indexation du collier de raccordement avec le manchon interne. le conteneur comporte des deuxièmes moyens d’indexation de la porte avec le manchon interne. le manchon externe est monté clippé sur le manchon interne. les manchons externe et interne sont dimensionnés l’un par rapport à l’autre pour mettre en appui sur le manchon interne un godron ménagé sur le manchon externe. les moyens de raccordement au dispositif de connexion complémentaire de l’enceinte sont formés d’une seul tenant avec le manchon extérieur. le conteneur comporte des moyens de serrage du manchon externe sur le manchon interne arrangés pour enserrer les parties du manchon externe et du manchon interne entre lesquelles le film souple est interposé. le conteneur comporte un joint annulaire logé dans une gorge périphérique interne du manchon externe, le film souple s’étendant entre le joint annulaire et le manchon interne. le manchon interne comporte une face pourvue d’un renfoncement d’appui situé en vis-à-vis de la gorge périphérique du manchon externe. le manchon interne comporte une zone crantée adjacente au renfoncement d’appui arrangée pour coopérer avec un crantage complémentaire ménagé sur la face interne du manchon externe. le manchon externe comporte une jupe inférieure comprenant des fentes longitudinales s’étendant depuis la bordure d’extrémité inférieure du manchon externe et équiréparties sur la périphérie dudit manchon de sorte à former des languettes élastiques aptes à exercer un effort de serrage sur le manchon interne. les languettes élastiques comportent des moyens d’association réciproque avec les moyens de serrage. le dispositif de connexion comporte une porte montée sur le manchon interne, obturant l’ouverture de passage. la bride comporte un joint annulaire ayant une section en forme sensiblement de L logé dans un espace délimité par le manchon externe, le manchon interne et la porte. le film souple et le dispositif de connexion sont réalisés en un matériau bactériostatique. According to other advantageous and non-limiting characteristics of the invention, taken alone or in any technically feasible combination: the internal sleeve is surrounded in the lower part by the external sleeve and in the upper part by a collar arranged to ensure the connection to the complementary connection device of the enclosure, the collar forming said connection means of the connection device. the container comprises first means for indexing the connecting collar with the internal sleeve. the container comprises second means for indexing the door with the internal sleeve. the outer sleeve is mounted clipped onto the inner sleeve. the outer and inner sleeves are dimensioned relative to each other so as to bring a gadroon formed on the outer sleeve to bear on the inner sleeve. the means of connection to the complementary connection device of the enclosure are formed integrally with the outer sleeve. the container comprises means for clamping the outer sleeve on the inner sleeve arranged to grip the parts of the outer sleeve and of the inner sleeve between which the flexible film is interposed. the container has an annular seal housed in an internal peripheral groove of the outer sleeve, the flexible film extending between the annular seal and the inner sleeve. the internal sleeve has a face provided with a bearing recess located opposite the peripheral groove of the external sleeve. the internal sleeve comprises a notched zone adjacent to the bearing recess arranged to cooperate with a complementary notch provided on the internal face of the external sleeve. the outer sleeve comprises a lower skirt comprising longitudinal slots extending from the lower end edge of the outer sleeve and evenly distributed over the periphery of said sleeve so as to form resilient tongues capable of exerting a clamping force on the inner sleeve. the elastic tongues comprise means of reciprocal association with the tightening means. the connection device comprises a door mounted on the internal sleeve, closing off the passage opening. the flange comprises an annular seal having a substantially L-shaped section housed in a space delimited by the outer sleeve, the inner sleeve and the door. the flexible film and the connection device are made of a bacteriostatic material.
BREVE DESCRIPTION DES FIGURES BRIEF DESCRIPTION OF THE FIGURES
D’autres caractéristiques et avantages de l’invention ressortiront de la description détaillée de l’invention qui va suivre en référence aux figures annexées et dans lesquelles : la figure 1 représente une vue schématique de face d’un conteneur selon l’invention ; la figure 2 représente une vue en coupe longitudinale partielle du conteneur de la figureOther characteristics and advantages of the invention will emerge from the detailed description of the invention which will follow with reference to the appended figures and in which: FIG. 1 represents a schematic front view of a container according to the invention; FIG. 2 represents a view in partial longitudinal section of the container of FIG.
1 ; la figure 3 représente une vue de détail du conteneur de la figure 2 ; la figure 4 représente une vue partielle du manchon externe 5 du dispositif de connexion du conteneur de la figure 2 ; la figure 5 représente une vue éclatée du dispositif de connexion du conteneur de la figure 1 ; la figure 6 représente une vue en perspective de dessus d’un dispositif de connexion du conteneur selon un autre exemple de réalisation de l’invention ; la figure 7 représente une vue en perspective de dessous du dispositif de connexion de la figure 6 ; la figure 8 représente une vue en coupe axiale du dispositif de connexion de la figure 6 ; la figure 9 représente une vue de détail de la figure 8 ; la figure 10 représente une vue en coupe de dessus selon l’axe XX du dispositif de connexion de la figure 9 ; la figure 11 représente une vue de détail de la figure 10 ; la figure 12 représente une vue en coupe de dessous selon l’axe XX du dispositif de connexion de la figure 9 ; la figure 13 représente une vue de détail de la figure 12 ; la figure 14 représente une vue de dessus du dispositif de connexion de la figure 6 ; la figure 15 représente une vue de détail de la figure 14. 1; FIG. 3 represents a detailed view of the container of FIG. 2; FIG. 4 represents a partial view of the outer sleeve 5 of the connection device of the container of FIG. 2; FIG. 5 represents an exploded view of the connection device of the container of FIG. 1; FIG. 6 shows a perspective view from above of a container connection device according to another exemplary embodiment of the invention; FIG. 7 represents a perspective view from below of the connection device of FIG. 6; FIG. 8 represents a view in axial section of the connection device of FIG. 6; FIG. 9 represents a detail view of FIG. 8; Figure 10 shows a top sectional view along axis XX of the connection device of Figure 9; FIG. 11 represents a detail view of FIG. 10; Figure 12 shows a sectional view from below along axis XX of the connection device of Figure 9; FIG. 13 represents a detail view of FIG. 12; FIG. 14 represents a top view of the connection device of FIG. 6; FIG. 15 represents a detailed view of FIG. 14.
[0015] Pour plus de clarté, les éléments identiques ou similaires des différents modes de réalisation sont repérés par des signes de référence identiques sur l’ensemble des figures. [0015] For greater clarity, identical or similar elements of the different embodiments are marked with identical reference signs in all of the figures.
[0016] Par le terme « inférieur », on désigne les parties constituant le conteneur ou les extrémités de ces parties les plus éloignées de l’ouverture de passage du conteneur et par le terme « supérieur », les parties constituant le conteneur ou les extrémités de ces parties les plus proches de l’ouverture de passage du conteneur. By the term "lower" is meant the parts constituting the container or the ends of these parts furthest from the passage opening of the container and by the term "upper", the parts constituting the container or the ends of those parts closest to the container passage opening.
DESCRIPTION DETAILLEE DE L’INVENTION DETAILED DESCRIPTION OF THE INVENTION
[0017] En relation avec les figures 1 à 5, il est décrit un conteneur 1 selon un premier exemple de réalisation de l’invention. Le conteneur 1 illustré comprend un film souple 2 arrangé pour définir un volume intérieur 3 et une ouverture de passage permettant de mettre en communication le volume intérieur 3 avec l’extérieur du film. Le conteneur comporte également un dispositif de connexion 4 étanche lequel est arrangé pour permettre la connexion du film souple 2 à un dispositif de connexion complémentaire d’une enceinte stérile. La connexion est réalisée de manière à assurer une communication stérile entre le volume intérieur 3 dudit conteneur 1 et celui de l’enceinte. In relation to Figures 1 to 5, there is described a container 1 according to a first embodiment of the invention. The illustrated container 1 comprises a flexible film 2 arranged to define an interior volume 3 and a passage opening making it possible to put the interior volume 3 in communication with the exterior of the film. The container also comprises a sealed connection device 4 which is arranged to allow connection of the flexible film 2 to a complementary connection device of a sterile enclosure. The connection is made so as to ensure sterile communication between the interior volume 3 of said container 1 and that of the enclosure.
[0018] Le dispositif de connexion 4 comprend une bride sur laquelle le film souple est fixé, ladite bride délimitant l’ouverture de passage du film souple, et des moyens de raccordement au dispositif de connexion complémentaire de l’enceinte. Selon l’invention, la bride est constituée de deux pièces distinctes l’une de l’autre, une première pièce formant un manchon dit externe 5 et une deuxième pièce formant un manchon dit interne 6, entre lesquels le film souple s’étend. The connection device 4 comprises a flange on which the flexible film is fixed, said flange delimiting the opening for the passage of the flexible film, and connection means to the complementary connection device of the enclosure. According to the invention, the flange consists of two separate pieces from each other, a first piece forming a so-called outer sleeve 5 and a second piece forming a so-called inner sleeve 6, between which the flexible film extends.
[0019] Le dispositif de connexion 4 comprend en outre une porte 7 amovible fixée sur la bride de façon à obturer l’ouverture de passage. Avantageusement, la bride et la porte 7 sont fixées l’une à l’autre au moyen d’encoches et d’oreilles portées respectivement par le manchon interne 6 et la porte 7. La bride définit ainsi une bride d’assemblage du film souple à la porte. The connection device 4 further comprises a removable door 7 fixed to the flange so as to close the passage opening. Advantageously, the flange and the door 7 are fixed to each other by means of notches and ears carried respectively by the internal sleeve 6 and the door 7. The flange thus defines an assembly flange of the flexible film. at the door.
[0020] Dans le mode de réalisation illustré, le manchon interne 6 comporte une zone crantée 64 adjacente au renfoncement d’appui 61 arrangée pour coopérer avec un crantage complémentaire 54 ménagé sur la face interne 50 du manchon externe 5. In the illustrated embodiment, the internal sleeve 6 comprises a notched zone 64 adjacent to the support recess 61 arranged to cooperate with a complementary notch 54 provided on the internal face 50 of the external sleeve 5.
[0021] Le manchon externe 5 comporte, selon une configuration avantageuse illustrée sur la figure 4, une jupe inférieure 10 comprenant des fentes longitudinales 11 s’étendant depuis la bordure d’extrémité inférieure dudit manchon. Ces fentes longitudinales 11 sont avantageusement équiréparties sur la périphérie dudit manchon. Elles délimitent ainsi des languettes élastiques 12 aptes à exercer un effort de serrage homogène sur l’ensemble de la périphérie extérieure du manchon interne 6 lorsque le manchon externe 5 est monté sur le manchon interne 6. Les languettes élastiques 12 comportent des moyens d’association réciproque avec respectivement des moyens de serrage, décrite ci-après, et le manchon interne 6. Dans l’exemple illustré, les moyens d’association réciproque avec la bague de serrage consistent en un filetage 53 et un crantage 54. Les moyens serrage sont arrangés pour enserrer les parties du manchon externe 5 et du manchon interne 6 entre lesquelles le film souple 2 est interposé. Dans l’exemple illustré, les moyens de serrage se présentent sous la forme d’une bague de serrage externe comprenant un taraudage 90 de forme complémentaire à un filetage 53 ménagé sur la face externe 52 du manchon externe 5. The outer sleeve 5 comprises, according to an advantageous configuration illustrated in Figure 4, a lower skirt 10 comprising longitudinal slots 11 extending from the lower end edge of said sleeve. These longitudinal slots 11 are advantageously evenly distributed over the periphery of said sleeve. They thus define resilient tongues 12 capable of exerting a homogeneous tightening force over the entire outer periphery of the inner sleeve 6 when the outer sleeve 5 is mounted on the inner sleeve 6. The resilient tongues 12 comprise association means. reciprocal with respectively clamping means, described below, and the internal sleeve 6. In the example illustrated, the means of reciprocal association with the clamping ring consist of a thread 53 and a notch 54. The clamping means are arranged to enclose the parts of the outer sleeve 5 and the inner sleeve 6 between which the film flexible 2 is interposed. In the example illustrated, the clamping means are in the form of an external clamping ring comprising an internal thread 90 of complementary shape to a thread 53 formed on the external face 52 of the external sleeve 5.
[0022] Dans l’exemple illustré, le manchon extérieur 5 comporte en périphérie supérieure, un arrangement d’oreilles formant les moyens de raccordement au dispositif de connexion complémentaire de l’enceinte. In the example illustrated, the outer sleeve 5 comprises at the upper periphery, an arrangement of ears forming the connection means to the complementary connection device of the enclosure.
[0023] Le conteneur 1 comporte en outre un premier joint annulaire 8 logé dans une gorge périphérique 51 ménagée sur la face interne 50 du manchon externe 5 et la face externe 60 du manchon interne 6. Comme montré sur la figure 3, le film souple 2 est maintenu en prise entre le joint annulaire 8 et le manchon interne 6. Afin d’améliorer la retenue du film souple 2 entre les deux manchons constitutifs de la bride d’assemblage, le manchon interne 6 comporte une face externe pourvue d’un renfoncement d’appui 61 situé en vis-à-vis de la gorge périphérique 51 du manchon externe 5. Ainsi, lors du serrage du manchon externe 5 sur le manchon interne 6, le joint annulaire 8 écrase le film souple 2 au niveau du renfoncement d’appui 61, assurant une mise en prise améliorée du film souple 2. The container 1 further comprises a first annular seal 8 housed in a peripheral groove 51 formed on the inner face 50 of the outer sleeve 5 and the outer face 60 of the inner sleeve 6. As shown in Figure 3, the flexible film 2 is held in engagement between the annular seal 8 and the internal sleeve 6. In order to improve the retention of the flexible film 2 between the two constituent sleeves of the assembly flange, the internal sleeve 6 has an external face provided with a bearing recess 61 located opposite the peripheral groove 51 of the outer sleeve 5. Thus, when the outer sleeve 5 is tightened on the inner sleeve 6, the annular seal 8 crushes the flexible film 2 at the level of the recess support 61, ensuring improved engagement of the flexible film 2.
[0024] Le conteneur 1 comporte en outre un deuxième joint annulaire 13 lequel est porté par la bride. Lorsque la porte est en position d’obturation de l’ouverture de passage, le joint annulaire 13 est logé dans l’espace délimité par le manchon externe 5, le manchon interne 6 et la porte 7. Avantageusement, le joint annulaire 13 présente une section de forme conjuguée à l’espace dans lequel il est logé. Dans le mode de réalisation illustré, le joint annulaire 13 présente une section en forme de L. The container 1 further comprises a second annular seal 13 which is carried by the flange. When the door is in the closed position of the passage opening, the annular seal 13 is housed in the space delimited by the outer sleeve 5, the inner sleeve 6 and the door 7. Advantageously, the annular seal 13 has a section of shape combined with the space in which it is housed. In the illustrated embodiment, the annular seal 13 has an L-shaped section.
[0025] Du fait de l’arrangement des éléments le composant, le dispositif de connexion est assemblé par simple clipsage des éléments selon l’empilement illustré sur la figure 5. Pour réaliser le conteneur 1 , la partie du film souple, située du côté de l’ouverture de passage, sera disposée de façon à être placée entre le manchon externe 5 et le manchon interne 6. Le serrage sera effectif par serrage de la bague 9 sur le manchon externe 6, entrainant le resserrement des languettes 12 contre le manchon interne 6. Le film souple 2 pourra être désassemblé en dévissant la bague de serrage 9 et en déclipsant le manchon externe 5 du manchon interne 6. Due to the arrangement of the elements composing it, the connection device is assembled by simple clipping of the elements according to the stack illustrated in FIG. 5. To make the container 1, the part of the flexible film, located on the side of the passage opening, will be arranged so as to be placed between the outer sleeve 5 and the inner sleeve 6. Tightening will be effective by clamping the ring 9 on the outer sleeve 6, causing the tongues 12 to tighten against the sleeve internal 6. The flexible film 2 can be disassembled by unscrewing the clamping ring 9 and unclipping the external sleeve 5 from the internal sleeve 6.
[0026] Dans le mode de réalisation qui vient d’être décrit, le manchon externe 5 assure conjointement la fonction de maintien du film souple 2 sur le manchon interne 6, et ainsi son assemblage à la porte 7 associée, et la fonction de raccordement au dispositif de connexion équipant une enceinte. Les figures 6 et suivantes illustrent un autre exemple de réalisation d’un conteneur selon l’invention dans lequel la fonction de raccordement au dispositif de connexion complémentaire est assurée, non plus directement par le manchon externe 5, mais par une pièce complémentaire qui sera décrite plus loin. In the embodiment which has just been described, the outer sleeve 5 jointly performs the function of holding the flexible film 2 on the inner sleeve 6, and thus its assembly to the associated door 7, and the connection function to the connection device fitted to an enclosure. Figures 6 and following illustrate another embodiment of a container according to the invention in which the connection function to the complementary connection device is provided, no longer directly by the external sleeve 5, but by a complementary part which will be described. further.
[0027] Comme dans la variante précédemment décrite, la bride d’assemblage de la porte 7 au film souple 2 est constituée d’un manchon externe 5 et d’un manchon interne 6 sur lequel la porte 7 est montée, le film souple 2 étant maintenu en prise entre ces deux manchons. Le manchon externe 5, lequel présente une longueur axiale inférieure à celle du manchon interne 6, est dimensionné pour encercler la partie inférieure du manchon interne 6. As in the variant described above, the assembly flange of the door 7 to the flexible film 2 consists of an outer sleeve 5 and an inner sleeve 6 on which the door 7 is mounted, the flexible film 2 being held in engagement between these two sleeves. The outer sleeve 5, which has an axial length less than that of the inner sleeve 6, is dimensioned to encircle the lower part of the inner sleeve 6.
[0028] Avantageusement, le manchon externe 5 est monté sur le manchon interne 6 par clippage. Pour ce faire, le manchon externe 5 comporte une gorge annulaire 15 arrangée pour s’engager sur une première ailette 20 circonférentielle de forme complémentaire ménagée sur la face extérieure du manchon interne 6. Advantageously, the outer sleeve 5 is mounted on the inner sleeve 6 by clipping. To do this, the outer sleeve 5 has an annular groove 15 arranged to engage with a first circumferential fin 20 of complementary shape provided on the outer face of the inner sleeve 6.
[0029] Le manchon externe 5 comporte en outre des clips 16 coopérant, lorsque ledit manchon est clippé sur le manchon interne 6, avec une empreinte complémentaire ménagée sur le manchon interne 6 (figure 10 et 11). Les clips 16 assurent ainsi le maintien de la position axiale du manchon externe 5 sur le manchon interne 6 d’une part et le maintien de la position angulaire du manchon externe 5 sur le manchon interne 6 d’autre part. Ils assurent ainsi une indexation axiale et angulaire du manchon externe 5 sur le manchon interne 6. The outer sleeve 5 further comprises clips 16 cooperating, when said sleeve is clipped onto the inner sleeve 6, with a complementary imprint made on the inner sleeve 6 (Figure 10 and 11). The clips 16 thus maintain the axial position of the outer sleeve 5 on the inner sleeve 6 on the one hand and maintain the angular position of the outer sleeve 5 on the inner sleeve 6 on the other hand. They thus ensure axial and angular indexing of the outer sleeve 5 on the inner sleeve 6.
[0030] Afin d’assurer le maintien du film en prise entre les deux manchons 5, 6 d’une part et l’étanchéité du manchon externe 5 avec le film souple 2 en prise entre les deux manchons d’autre part, le manchon externe 5 présente une face périphérique interne pourvue d’un godron circonférentiel 14 arrangé pour définir, avec la face périphérique externe du manchon interne 6 une zone de compression de la portion de film 20 en prise entre les manchons (figures 8 et 9). La forme des manchons externe 5 et interne 6 sont définis nominalement de sorte que le godron 14 présent sur le manchon externe 5 vienne en interférence avec le manchon interne 6. Plaqué et exerçant un effort radial sur la face périphérique externe du manchon interne 6, le godron 16 assure la fonction de joint d’étanchéité. Dans le mode de réalisation illustré, la pièce annulaire interne 7 comporte un seul godron 14 situé en extrémité inférieure du manchon externe 5 et s’étendant sur toute la circonférence de la face périphérique interne dudit manchon. Il est bien entendu évident qu’il peut être prévu plusieurs godrons différents sans sortir du cadre de l’invention. To ensure the maintenance of the film engaged between the two sleeves 5, 6 on the one hand and the sealing of the outer sleeve 5 with the flexible film 2 engaged between the two sleeves on the other hand, the sleeve external 5 has an internal peripheral face provided with a circumferential gadroon 14 arranged to define, with the external peripheral face of the internal sleeve 6, a zone of compression of the portion of film 20 engaged between the sleeves (FIGS. 8 and 9). The shape of the outer 5 and inner 6 sleeves are nominally defined so that the gadroon 14 present on the outer sleeve 5 interferes with the inner sleeve 6. Plated and exerting a radial force on the outer peripheral face of the inner sleeve 6, the gadroon 16 acts as a seal. In the illustrated embodiment, the internal annular part 7 comprises a single gadroon 14 located at the lower end of the external sleeve 5 and extending over the entire circumference of the face. internal peripheral of said sleeve. It is of course obvious that several different gadroons can be provided without departing from the scope of the invention.
[0031] En complément du manchon externe 5, le manchon interne 6 est pourvu en partie supérieure d’un collier 30 portant les moyens de raccordement 31 au dispositif de connexion complémentaire de l’enceinte. Le collier 30 forme ainsi une bride dite de raccordement. Le collier 30 sera par la suite désigné de collier ou bride de raccordement. In addition to the outer sleeve 5, the inner sleeve 6 is provided in the upper part with a collar 30 carrying the connection means 31 to the complementary connection device of the enclosure. The collar 30 thus forms a so-called connecting flange. The collar 30 will hereinafter be referred to as the connection collar or flange.
[0032] Le collier de raccordement 30 est monté au niveau de l’extrémité supérieure du manchon interne 6 par clippage conjoint avec le joint d’étanchéité 13 et la porte 7 (figures 8 et 9). Le collier de raccordement 30 comporte une extension interne 32 circonférentielle dimensionnée pour s’engager en force dans la cavité du joint 13. Il comporte en outre avantageusement en partie inférieure une empreinte annulaire 33 en creux dans laquelle une deuxième ailette 22 circonférentielle du manchon interne 6 vient s’engager. The connecting collar 30 is mounted at the upper end of the internal sleeve 6 by joint clipping with the seal 13 and the door 7 (Figures 8 and 9). The connection collar 30 comprises a circumferential internal extension 32 dimensioned to engage in force in the cavity of the seal 13. It also advantageously comprises in the lower part an annular recess 33 in which a second circumferential fin 22 of the internal sleeve 6 comes to engage.
[0033] Avantageusement, le conteneur comporte des premiers moyens d’indexation 40 du collier de raccordement 30 avec le manchon interne 6, illustrés sur les figures 12 et 13, et des deuxièmes moyens d’indexation 41 de la porte 7 avec le manchon interne 6, illustrés sur les figures 14 et 15, Les premiers et deuxièmes moyens d’indexation sont, dans l’exemple illustré, des doigts radiaux. Advantageously, the container comprises first indexing means 40 of the connecting collar 30 with the internal sleeve 6, illustrated in Figures 12 and 13, and second indexing means 41 of the door 7 with the internal sleeve 6, illustrated in Figures 14 and 15, the first and second indexing means are, in the example illustrated, radial fingers.
[0034] Dans cette variante, la bague de serrage et le joint d’étanchéité 8 associé ne sont plus nécessaires pour assurer respectivement le maintien du film souple 2 et l’étanchéité de l’ensemble, ces fonctionnalités étant conjointement assurées par le manchon externe 5 monté en force sur le manchon interne 6, et le godron associé. Afin de renforcer l’étanchéité de l’ensemble assuré par le godron 14, le film souple 2 est, de manière avantageuse, préalablement thermoformé sur le manchon interne 6 de façon à former une ligne de contact annulaire étanche sur la surface du manchon interne 6. Le thermoformage sera réalisé à la limite de la soudure du film souple sur le manchon interne 6 afin d’assurer une fixation satisfaisante du film tout en préservant son intégrité. La réalisation de la ligne de contact est réalisée de manière à être située au-dessus du godron 14 lorsque le manchon externe 5 est emmanché sur le manchon interne 6. Ainsi au montage, le film souple 2 est pincé et l'effort est maintenu par l'élasticité des deux bagues qui se sont déformées sous l'effort lié au déplacement induit par l'interférence définie entre le godron 14 et le manchon interne 6. [0035] Avantageusement, le manchon interne 6 comporte un chanfrein externe 21, de forme conique, réalisé en extrémité inférieure dudit manchon (figure 8 et 9) pour faciliter l’enfilement et le glissement du film souple 2 sur le manchon interne 6. Par ailleurs, et comme dans l’exemple précédemment décrit, le manchon interne 6 et la porte 7 sont pourvus respectivement d’encoches 70 et d’oreilles permettant leur assemblage par clippage. In this variant, the clamping ring and the associated seal 8 are no longer necessary to ensure respectively the maintenance of the flexible film 2 and the sealing of the assembly, these functions being jointly provided by the outer sleeve 5 force-mounted on the internal sleeve 6, and the associated gadroon. In order to reinforce the tightness of the assembly provided by the gadroon 14, the flexible film 2 is, advantageously, previously thermoformed on the internal sleeve 6 so as to form a sealed annular contact line on the surface of the internal sleeve 6. The thermoforming will be carried out at the limit of the weld of the flexible film on the internal sleeve 6 in order to ensure satisfactory fixing of the film while preserving its integrity. The production of the contact line is made so as to be located above the gadroon 14 when the outer sleeve 5 is fitted onto the inner sleeve 6. Thus during assembly, the flexible film 2 is pinched and the force is maintained by the elasticity of the two rings which are deformed under the force associated with the displacement induced by the interference defined between the gadroon 14 and the internal sleeve 6. Advantageously, the internal sleeve 6 comprises an external chamfer 21, of conical shape, produced at the lower end of said sleeve (FIG. 8 and 9) to facilitate the threading and sliding of the flexible film 2 on the internal sleeve 6. By elsewhere, and as in the example described above, the internal sleeve 6 and the door 7 are provided respectively with notches 70 and ears allowing their assembly by clipping.
[0036] Le film souple 2 et le dispositif de connexion 4 sont avantageusement réalisés en un matériau bactériostatique. Les joints d’étanchéité 8 et 13 sont réalisés en un matériau silicone ou autres matériaux minimisant les phénomènes de rémanence. Il peut être prévu également que les joints d’étanchéité soient réalisés en un matériau bactériostatique. [0037] L’invention est décrite dans ce qui précède à titre d’exemple. Il est entendu que l’homme du métier est à même de réaliser différentes variantes de réalisation de l’invention sans pour autant sortir du cadre de l’invention. The flexible film 2 and the connection device 4 are advantageously made of a bacteriostatic material. The seals 8 and 13 are made of a silicone material or other materials minimizing the phenomena of persistence. Provision can also be made for the seals to be made of a bacteriostatic material. The invention is described in the foregoing by way of example. It is understood that a person skilled in the art is able to carry out different embodiments of the invention without however departing from the scope of the invention.

Claims

REVENDICATIONS
1. Conteneur (1) étanche comprenant un film souple (2) arrangé pour définir un volume intérieur (3) et une ouverture de passage, une porte (7) obturant l’ouverture de passage ainsi qu’un dispositif de connexion (4) étanche arrangé pour permettre la connexion du film souple (2) à un dispositif de connexion complémentaire d’une enceinte stérile en assurant une communication stérile entre le volume intérieur (3) dudit conteneur (1) et celui de l’enceinte, le dispositif de connexion (4) comprenant une bride d’assemblage de la porte (7) au film souple et des moyens de raccordement au dispositif de connexion complémentaire de l’enceinte, ladite bride d’assemblage délimitant l’ouverture de passage du film souple (2), caractérisé en ce que la bride d’assemblage est constituée de deux pièces distinctes l’une de l’autre, formant respectivement un manchon externe (5) et un manchon interne (6) sur lequel la porte (7) est montée, le film souple (2) étant maintenu en prise entre le manchon externe (5) et le manchon interne (6). 1. Waterproof container (1) comprising a flexible film (2) arranged to define an interior volume (3) and a passage opening, a door (7) closing off the passage opening and a connection device (4) sealed arranged to allow the connection of the flexible film (2) to a complementary connection device of a sterile enclosure ensuring sterile communication between the interior volume (3) of said container (1) and that of the enclosure, the device of connection (4) comprising a flange for assembling the door (7) to the flexible film and means for connecting to the complementary connection device of the enclosure, said assembly flange delimiting the opening for passage of the flexible film (2 ), characterized in that the assembly flange consists of two separate parts, respectively forming an outer sleeve (5) and an inner sleeve (6) on which the door (7) is mounted, the flexible film (2) being held in engagement between the outer sleeve ( 5) and the internal sleeve (6).
2. Conteneur (1) étanche selon la revendication 1 , caractérisé en ce que le manchon interne (6) est ceinturé en partie inférieure par le manchon externe (5) et en partie supérieure par un collier arrangé pour assurer le raccordement au dispositif de connexion complémentaire de l’enceinte, le collier formant lesdits moyens de raccordement. 2. A sealed container (1) according to claim 1, characterized in that the internal sleeve (6) is surrounded in the lower part by the external sleeve (5) and in the upper part by a collar arranged to ensure the connection to the connection device. complementary to the enclosure, the collar forming said connection means.
3. Conteneur (1) étanche selon la revendication 2, caractérisé en ce qu’il comporte des premiers moyens d’indexation (40) du collier de raccordement (30) avec le manchon interne (6). 3. A sealed container (1) according to claim 2, characterized in that it comprises first indexing means (40) of the connecting collar (30) with the internal sleeve (6).
4. Conteneur (1) étanche selon la revendication 2 ou la revendication 3, caractérisé en ce qu’il comporte des deuxièmes moyens d’indexation (41) de la porte (7) avec le manchon interne (6). 4. A sealed container (1) according to claim 2 or claim 3, characterized in that it comprises second indexing means (41) of the door (7) with the internal sleeve (6).
5. Conteneur (1) étanche selon l'un quelconque des revendications 1 à 4, caractérisé en ce que les manchons externe (5) et interne (6) sont dimensionnés l’un par rapport à l’autre pour mettre en appui sur le manchon interne (6) un godron ménagé sur le manchon externe (5). 5. A sealed container (1) according to any one of claims 1 to 4, characterized in that the outer (5) and inner (6) sleeves are dimensioned with respect to each other to bear on the inner sleeve (6) a gadroon formed on the outer sleeve (5).
6. Conteneur (1) étanche selon la revendication 1, caractérisé en ce que les moyens de raccordement (31) au dispositif de connexion complémentaire de l’enceinte sont formés d’une seul tenant avec le manchon extérieur (5). 6. A sealed container (1) according to claim 1, characterized in that the connection means (31) to the complementary connection device of the enclosure are formed integrally with the outer sleeve (5).
7. Conteneur (1) étanche selon la revendication 1 ou la revendication 6, caractérisé en ce qu’il comporte des moyens de serrage du manchon externe (5) sur le manchon interne (6) arrangés pour enserrer les parties du manchon externe (5) et du manchon interne (6) entre lesquelles le film souple est interposé. 7. A sealed container (1) according to claim 1 or claim 6, characterized in that it comprises means for clamping the outer sleeve (5) on the inner sleeve. (6) arranged to enclose the parts of the outer sleeve (5) and of the inner sleeve (6) between which the flexible film is interposed.
8. Conteneur (1) étanche selon les revendications 1, 6 ou 7, caractérisé en ce qu’il comporte un joint annulaire (8) logé dans une gorge périphérique (51) interne du manchon externe (5), le film souple (2) s’étendant entre le joint annulaire (8) et le manchon interne (6). 8. A sealed container (1) according to claims 1, 6 or 7, characterized in that it comprises an annular seal (8) housed in a peripheral groove (51) internal to the outer sleeve (5), the flexible film (2) ) extending between the annular seal (8) and the inner sleeve (6).
9. Conteneur (1) étanche selon la revendication précédente, caractérisé en ce que le manchon interne (6) comporte une face pourvue d’un renfoncement d’appui (61) situé en vis-à-vis de la gorge périphérique (51) du manchon externe (5). 9. A sealed container (1) according to the preceding claim, characterized in that the internal sleeve (6) has a face provided with a bearing recess (61) located vis-à-vis the peripheral groove (51) of the outer sleeve (5).
10. Conteneur (1) étanche selon la revendication 9, caractérisé en ce que le manchon interne (6) comporte une zone crantée (64) adjacente au renfoncement d’appui (61) arrangée pour coopérer avec un crantage complémentaire (54) ménagé sur la face interne du manchon externe (5). 10. A sealed container (1) according to claim 9, characterized in that the internal sleeve (6) comprises a notched zone (64) adjacent to the bearing recess (61) arranged to cooperate with a complementary notch (54) provided on the inner face of the outer sleeve (5).
11. Conteneur (1) étanche selon l'une quelconque des revendications 1 et 6 à 10, caractérisé en ce que le manchon externe (5) comporte une jupe inférieure (10) comprenant des fentes longitudinales (11) s’étendant depuis la bordure d’extrémité inférieure du manchon externe (5) et équiréparties sur la périphérie dudit manchon de sorte à former des languettes élastiques (12) aptes à exercer un effort de serrage sur le manchon interne (6). 11. A sealed container (1) according to any one of claims 1 and 6 to 10, characterized in that the outer sleeve (5) comprises a lower skirt (10) comprising longitudinal slots (11) extending from the edge. lower end of the outer sleeve (5) and evenly distributed over the periphery of said sleeve so as to form resilient tongues (12) capable of exerting a clamping force on the inner sleeve (6).
12. Conteneur (1) étanche selon la revendication précédente, caractérisé en ce que les languettes élastiques (12) comportent des moyens d’association réciproque avec les moyens de serrage. 12. Waterproof container (1) according to the preceding claim, characterized in that the elastic tabs (12) comprise reciprocal association means with the clamping means.
13. Conteneur (1) étanche selon l'un quelconque des revendications précédentes, caractérisé en ce que le manchon externe (5) est monté clippé sur le manchon interne (6). 13. A sealed container (1) according to any one of the preceding claims, characterized in that the outer sleeve (5) is clipped onto the inner sleeve (6).
14. Conteneur (1) étanche selon l'un quelconque des revendications précédentes, caractérisé en ce que la bride comporte un joint annulaire (13) ayant une section en forme sensiblement de L logé dans un espace délimité par le manchon externe (5), le manchon interne (6) et la porte (7). 14. A sealed container (1) according to any one of the preceding claims, characterized in that the flange comprises an annular seal (13) having a substantially L-shaped section housed in a space delimited by the outer sleeve (5), the internal sleeve (6) and the door (7).
15. Conteneur (1) étanche selon l'une quelconque des revendications précédentes, caractérisé en ce que le film souple (2) et le dispositif de connexion (4) sont réalisés en un matériau bactériostatique. 15. A sealed container (1) according to any one of the preceding claims, characterized in that the flexible film (2) and the connection device (4) are made of a bacteriostatic material.
EP20816272.7A 2019-11-05 2020-11-05 Sealed container comprising a device for releasable connection to an enclosure Pending EP4054764A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1912407A FR3102698B1 (en) 2019-11-05 2019-11-05 WATERPROOF CONTAINER COMPRISING A DEVICE FOR REMOVABLE CONNECTION TO A SPEAKER
PCT/FR2020/052007 WO2021089949A1 (en) 2019-11-05 2020-11-05 Sealed container comprising a device for releasable connection to an enclosure

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EP4054764A1 true EP4054764A1 (en) 2022-09-14

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EP (1) EP4054764A1 (en)
JP (1) JP2023501271A (en)
CN (1) CN114829012A (en)
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WO (1) WO2021089949A1 (en)

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DE102022131808A1 (en) 2022-11-30 2024-06-06 Groninger & Co. Gmbh Functional element, beta container system, transfer system and barrier system

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FR2674225B1 (en) * 1991-03-20 1993-07-16 Euritech PROCESS AND INSTALLATION FOR TRANSFERRING PRODUCTS FROM A CONTAMINATED ENCLOSURE TO A SECOND ENCLOSURE, WITHOUT CONTAMINATING THE LATTER.
US5735609A (en) * 1996-07-16 1998-04-07 The West Company Container for holding sterilized elements
AU732709B2 (en) * 1997-07-23 2001-04-26 Amcad Holdings Limited Open mouth bag
FR2787190B1 (en) * 1998-12-11 2001-02-16 Becton Dickinson France DEVICE FOR DETECTING THE SEALING OF THE CONNECTION BETWEEN THE ELEMENTS OF A DEVICE FOR SEALING TWO ISOLATED ENCLOSURES FROM THE EXTERNAL ENVIRONMENT
FR2833745B1 (en) * 2001-12-14 2004-10-01 Becton Dickinson France PROTECTION DEVICE FOR STERILE SPEAKER
US20060110077A1 (en) * 2004-11-06 2006-05-25 Scholle Corporation Oxygen impermeable bag-in-box container and methof of making
FR2955842B1 (en) * 2010-02-04 2012-03-16 Thea Lab FLUID FOR PACKAGING A LIQUID WITH A DROP-IN DISTRIBUTION HEAD
US20120153610A1 (en) * 2010-12-20 2012-06-21 Thomas Mitchel Young Aseptic transfer port
FR3046206B1 (en) * 2015-12-23 2018-01-12 Sartorius Stedim Aseptics METHOD FOR MANUFACTURING A SEALED CONTAINER
CN106586189B (en) * 2016-11-27 2020-12-29 苏州慧登塑胶有限公司 Packing box (Chinese character' jiangsu
CN109675079A (en) * 2018-12-19 2019-04-26 郑琼华 Desinfection chamber conveys article mechanism and desinfection chamber conveys article method
FR3105186B1 (en) * 2019-12-20 2021-11-12 Abc Transfer WATERPROOF CONTAINER INCLUDING A DEVICE ALLOWING REMOVABLE CONNECTION TO A SPEAKER

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US20220396403A1 (en) 2022-12-15
CN114829012A (en) 2022-07-29
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FR3102698B1 (en) 2023-03-03
WO2021089949A1 (en) 2021-05-14

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