EP3996748A4 - Smart temperature-sensitive hydrogels with antifungal property that perform controlled drug release - Google Patents

Smart temperature-sensitive hydrogels with antifungal property that perform controlled drug release Download PDF

Info

Publication number
EP3996748A4
EP3996748A4 EP20836170.9A EP20836170A EP3996748A4 EP 3996748 A4 EP3996748 A4 EP 3996748A4 EP 20836170 A EP20836170 A EP 20836170A EP 3996748 A4 EP3996748 A4 EP 3996748A4
Authority
EP
European Patent Office
Prior art keywords
drug release
controlled drug
antifungal property
perform controlled
sensitive hydrogels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP20836170.9A
Other languages
German (de)
French (fr)
Other versions
EP3996748A2 (en
Inventor
Bahar KANCI BOZOGLAN
Sibel TUNC
Osman Duman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akdeniz Universitesi
Original Assignee
Akdeniz Universitesi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akdeniz Universitesi filed Critical Akdeniz Universitesi
Publication of EP3996748A2 publication Critical patent/EP3996748A2/en
Publication of EP3996748A4 publication Critical patent/EP3996748A4/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP20836170.9A 2019-07-09 2020-07-07 Smart temperature-sensitive hydrogels with antifungal property that perform controlled drug release Pending EP3996748A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2019/10214A TR201910214A2 (en) 2019-07-09 2019-07-09 INTELLIGENT HYDROGELS WITH ANTIFUNGAL FEATURES THAT DELIVER CONTROLLED DRUGS SENSITIVE TO TEMPERATURE
PCT/TR2020/050592 WO2021006845A2 (en) 2019-07-09 2020-07-07 Smart temperature-sensitive hydrogels with antifungal property that perform controlled drug release

Publications (2)

Publication Number Publication Date
EP3996748A2 EP3996748A2 (en) 2022-05-18
EP3996748A4 true EP3996748A4 (en) 2023-09-13

Family

ID=74114203

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20836170.9A Pending EP3996748A4 (en) 2019-07-09 2020-07-07 Smart temperature-sensitive hydrogels with antifungal property that perform controlled drug release

Country Status (3)

Country Link
EP (1) EP3996748A4 (en)
TR (1) TR201910214A2 (en)
WO (1) WO2021006845A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115160613B (en) * 2022-08-17 2023-07-18 江苏省农业科学院 Preparation process of fresh-keeping hydrogel film
CN116535541A (en) * 2023-04-25 2023-08-04 武汉大学 Preparation method and application of thermosensitive methylated chitin
CN117700777B (en) * 2024-02-06 2024-04-09 上海瑛泰璞润医疗器械有限公司 Ultrasonic temperature measurement gel and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101260191A (en) * 2008-04-01 2008-09-10 武汉大学 Temperature sensitive type chitosan/glutin hydrogel and its preparation method and use
WO2010109418A1 (en) * 2009-03-25 2010-09-30 Sulur Subramaniam Vanangamudi A medicinal antifungal cream and a process to make it

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0024489D0 (en) 2000-10-06 2000-11-22 Reckitt Benckiser Uk Ltd Improvements in or relating to organic compositions
ES2371898B2 (en) * 2011-09-29 2012-06-13 Universidade De Santiago De Compostela CYCLODEXTRINE NANOGELS.
CN103524795A (en) * 2012-07-06 2014-01-22 中国科学院大连化学物理研究所 Thermo-sensitive type injectable chitosan hydrogel product and applications thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101260191A (en) * 2008-04-01 2008-09-10 武汉大学 Temperature sensitive type chitosan/glutin hydrogel and its preparation method and use
WO2010109418A1 (en) * 2009-03-25 2010-09-30 Sulur Subramaniam Vanangamudi A medicinal antifungal cream and a process to make it

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BOZOGLAN BAHAR KANCI ET AL: "Preparation and characterization of thermosensitive chitosan/carboxymethylcellulose/scleroglucan nanocomposite hydrogels", INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, ELSEVIER BV, NL, vol. 162, 15 June 2020 (2020-06-15), pages 781 - 797, XP086280564, ISSN: 0141-8130, [retrieved on 20200615], DOI: 10.1016/J.IJBIOMAC.2020.06.087 *
KANCI BOZOGLAN BAHAR ET AL: "Smart antifungal thermosensitive chitosan/carboxymethylcellulose/scleroglucan/montmorillonite nanocomposite hydrogels for onychomycosis treatment", COLLOIDS AND SURFACES A : PHYSIOCHEMICAL AND ENGINEERINGS ASPECTS, ELSEVIER, AMSTERDAM, NL, vol. 610, 26 October 2020 (2020-10-26), XP086425431, ISSN: 0927-7757, [retrieved on 20201026], DOI: 10.1016/J.COLSURFA.2020.125600 *
See also references of WO2021006845A2 *

Also Published As

Publication number Publication date
WO2021006845A2 (en) 2021-01-14
EP3996748A2 (en) 2022-05-18
WO2021006845A3 (en) 2021-03-11
TR201910214A2 (en) 2021-01-21

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Ipc: A61K 9/06 20060101ALI20230810BHEP

Ipc: C08J 3/075 20060101ALI20230810BHEP

Ipc: A61K 47/36 20060101AFI20230810BHEP