EP3962433A1 - Cosmetic oil-in-water emulsion containing scleroglucane - Google Patents
Cosmetic oil-in-water emulsion containing scleroglucaneInfo
- Publication number
- EP3962433A1 EP3962433A1 EP20725688.4A EP20725688A EP3962433A1 EP 3962433 A1 EP3962433 A1 EP 3962433A1 EP 20725688 A EP20725688 A EP 20725688A EP 3962433 A1 EP3962433 A1 EP 3962433A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- emulsion
- emulsifiers
- weight
- emulsions
- emulsions according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007764 o/w emulsion Substances 0.000 title claims abstract description 14
- 239000002537 cosmetic Substances 0.000 title claims abstract description 12
- 239000000839 emulsion Substances 0.000 claims abstract description 52
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 35
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 125000000129 anionic group Chemical group 0.000 claims abstract description 6
- FEBUJFMRSBAMES-UHFFFAOYSA-N 2-[(2-{[3,5-dihydroxy-2-(hydroxymethyl)-6-phosphanyloxan-4-yl]oxy}-3,5-dihydroxy-6-({[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-4-yl)oxy]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl phosphinite Chemical compound OC1C(O)C(O)C(CO)OC1OCC1C(O)C(OC2C(C(OP)C(O)C(CO)O2)O)C(O)C(OC2C(C(CO)OC(P)C2O)O)O1 FEBUJFMRSBAMES-UHFFFAOYSA-N 0.000 claims description 15
- 229920002305 Schizophyllan Polymers 0.000 claims description 15
- OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 claims description 7
- -1 fatty acid esters Chemical class 0.000 claims description 5
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 4
- 229930195729 fatty acid Natural products 0.000 claims description 4
- 239000000194 fatty acid Substances 0.000 claims description 4
- 229940061570 polyglyceryl-10 stearate Drugs 0.000 claims description 4
- RMGVATURDVPNOZ-UHFFFAOYSA-M potassium;hexadecyl hydrogen phosphate Chemical compound [K+].CCCCCCCCCCCCCCCCOP(O)([O-])=O RMGVATURDVPNOZ-UHFFFAOYSA-M 0.000 claims description 3
- RFVNOJDQRGSOEL-UHFFFAOYSA-N 2-hydroxyethyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCO RFVNOJDQRGSOEL-UHFFFAOYSA-N 0.000 claims description 2
- RMTFNDVZYPHUEF-XZBKPIIZSA-N 3-O-methyl-D-glucose Chemical compound O=C[C@H](O)[C@@H](OC)[C@H](O)[C@H](O)CO RMTFNDVZYPHUEF-XZBKPIIZSA-N 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- 239000002202 Polyethylene glycol Substances 0.000 claims description 2
- 229920002701 Polyoxyl 40 Stearate Polymers 0.000 claims description 2
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 2
- FRGAIZLZPOROJH-BKIJVIAGSA-N [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-hydroxy-3-[2-hydroxy-3-(2-hydroxy-3-octadecanoyloxypropoxy)propoxy]propoxy]oxan-2-yl]methyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)COCC(O)COCC(O)CO[C@H]1O[C@H](COC(=O)CCCCCCCCCCCCCCCCC)[C@@H](O)[C@H](O)[C@H]1O FRGAIZLZPOROJH-BKIJVIAGSA-N 0.000 claims description 2
- 150000001447 alkali salts Chemical class 0.000 claims description 2
- 229930195712 glutamate Natural products 0.000 claims description 2
- 229920001223 polyethylene glycol Polymers 0.000 claims description 2
- 150000004671 saturated fatty acids Chemical class 0.000 claims description 2
- 235000003441 saturated fatty acids Nutrition 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- RYYKJJJTJZKILX-UHFFFAOYSA-M sodium octadecanoate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 claims description 2
- 239000012071 phase Substances 0.000 description 14
- 238000002360 preparation method Methods 0.000 description 9
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 6
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- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 5
- 239000007788 liquid Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 241001558929 Sclerotium <basidiomycota> Species 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000006071 cream Substances 0.000 description 3
- 150000002632 lipids Chemical class 0.000 description 3
- 239000006210 lotion Substances 0.000 description 3
- VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical compound OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
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- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- DURPTKYDGMDSBL-UHFFFAOYSA-N 1-butoxybutane Chemical compound CCCCOCCCC DURPTKYDGMDSBL-UHFFFAOYSA-N 0.000 description 2
- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical compound C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 description 2
- NKEQOUMMGPBKMM-UHFFFAOYSA-N 2-hydroxy-2-[2-(2-hydroxy-3-octadecanoyloxypropoxy)-2-oxoethyl]butanedioic acid Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)COC(=O)CC(O)(C(O)=O)CC(O)=O NKEQOUMMGPBKMM-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 description 2
- 239000004904 UV filter Substances 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 229920000591 gum Polymers 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- DBSABEYSGXPBTA-RXSVEWSESA-N (2r)-2-[(1s)-1,2-dihydroxyethyl]-3,4-dihydroxy-2h-furan-5-one;phosphoric acid Chemical compound OP(O)(O)=O.OC[C@H](O)[C@H]1OC(=O)C(O)=C1O DBSABEYSGXPBTA-RXSVEWSESA-N 0.000 description 1
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- 238000005470 impregnation Methods 0.000 description 1
- 239000008384 inner phase Substances 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 150000003893 lactate salts Chemical class 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 229960004488 linolenic acid Drugs 0.000 description 1
- 229940100573 methylpropanediol Drugs 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000005152 nicotinamide Nutrition 0.000 description 1
- 239000011570 nicotinamide Substances 0.000 description 1
- 229960003966 nicotinamide Drugs 0.000 description 1
- OEIJHBUUFURJLI-UHFFFAOYSA-N octane-1,8-diol Chemical compound OCCCCCCCCO OEIJHBUUFURJLI-UHFFFAOYSA-N 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 229940101267 panthenol Drugs 0.000 description 1
- 235000020957 pantothenol Nutrition 0.000 description 1
- 239000011619 pantothenol Substances 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 229960005323 phenoxyethanol Drugs 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- GHBFNMLVSPCDGN-UHFFFAOYSA-N rac-1-monooctanoylglycerol Chemical compound CCCCCCCC(=O)OCC(O)CO GHBFNMLVSPCDGN-UHFFFAOYSA-N 0.000 description 1
- 235000019172 retinyl palmitate Nutrition 0.000 description 1
- 229940108325 retinyl palmitate Drugs 0.000 description 1
- 239000011769 retinyl palmitate Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 229960003080 taurine Drugs 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 229940045136 urea Drugs 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 150000003700 vitamin C derivatives Chemical class 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 239000007762 w/o emulsion Substances 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/062—Oil-in-water emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Definitions
- the present invention relates to a cosmetic preparation containing scleroglucan.
- Emulsions are generally understood to mean heterogeneous systems which consist of two liquids which are immiscible or only partially miscible with one another, which are usually referred to as phases and in which one of the two liquids is dispersed in the other liquid in the form of very fine droplets. Externally and with the naked eye, emulsions appear homogeneous.
- the two liquids are water and oil and if oil droplets are finely distributed in water, then it is an oil-in-water emulsion (O / W emulsion, e.g. milk).
- O / W emulsion oil-in-water emulsion
- the basic character of an O / W emulsion is shaped by the water.
- W / O emulsion water-in-oil emulsion, e.g. butter
- so-called emulsifiers are added to the emulsions.
- Emulsifiers are usually molecules with a polar, hydrophilic structural element and a non-polar, lipophilic structural element.
- a so-called HLB value (a dimensionless number between 0 and 20) is assigned to each emulsifier, which indicates whether the water or oil solubility is preferred. Numbers under 8 indicate oil-soluble, hydrophobic emulsifiers, numbers over 8 indicate water-soluble, hydrophilic emulsifiers.
- the water phase is combined with the lipid phase (oil phase) with stirring, the droplets of the inner phase of the emulsion having to be broken down to a size of less than 10 ⁇ m so that the emulsion becomes stable.
- O / W emulsions with hydrophilic emulsifiers (emulsifiers with an HLB value of greater than / equal to 8)
- the problem often arises that when predominantly medium-polar to polar lipids are used in the oil phase (i.e. lipids with an interfacial tension against water of less than 30 mN / m) an undesirable phase reversal can take place.
- O / W emulsions tend to reverse phase during storage; H. the preparations are often not particularly stable in storage.
- the object is surprisingly achieved by cosmetic oil-in-water emulsions (O / W emulsions) containing, in addition to a water phase, one or more oil phases dispersed therein as well
- Scleroglucan is released into the surrounding medium as a microbial exopolysaccharide by fungal species of the genus Sclerotium (Basidiomycota, Agariomycetes). Sclerotium delphinii for example is a major pest of plants. Scleroglucan is also known as Sclerotium Gum (INCI: Sclerotium Gum).
- Scleroglucan is a (1—>3;1—> 6) - ⁇ -D-glucan. Its mean molar mass is about 5.7 * 10 6 g / mol, its average degree of polymerization about 35,000.
- Scleroglucan consists of a linear (1—> 3) - ⁇ -D-glucan chain (O d HioO d OQHIOOd) ⁇ , on which statistically every third glucose unit with a single (1—> 6) - ⁇ -D- Glcp residue is branched.
- Scleroglucan is readily soluble in water and can be used as a thickener.
- the use of scleroglucan in cosmetic emulsions is known per se to the person skilled in the art, but the prior art could not point the way to the present invention.
- DE 10 2014 015 554 discloses the use of scleroglucan in UV filters containing cosmetic preparations to reduce the contamination and / or discoloration of textiles caused by the UV filters in the preparation.
- EP 1 132 076 describes thickened hair compositions containing scleroglucan.
- the emulsion according to the invention is characterized in that the content of scleroglucan in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.01 and 1.5% by weight, particularly preferably between 0, 1 and
- the emulsion contains one or more oil-in-water emulsifiers (O / W emulsifiers) in a total concentration of 0.05 to 5.0% by weight and preferably in a total concentration of 2.0 to 4.0% by weight, based in each case on the total weight of the emulsion.
- O / W emulsifiers oil-in-water emulsifiers
- the emulsion according to the invention is characterized in that the content of one or more anionic emulsifiers in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.05 and
- the emulsion according to the invention is characterized in that the content of one or more nonionic emulsifiers in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.05 and
- the emulsion according to the invention is characterized in that hydrophilic emulsifiers with an HLB value of greater than or equal to 8 are used as O / W emulsifiers.
- HLB value of emulsifiers can be found in the usual standard works (e.g. Fiedler, Lexicon of Auxiliaries for Pharmacy, Cosmetics and Neighboring Areas, Editio Cantor Verlag, Aulendorf).
- the emulsion according to the invention is characterized in that, as O / W emulsifiers, glyceryl stearate citrate (CAS 39175-72-9, INCI Glyceryl Stearate Citrate, e.g. Imwitor 370 from Hüls), polyglyceryl-3 methylglucose distearate (INCI Polyglyceryl Methyl Glucose Distearate, e.g. Tego Care 450 from Evonik) and / or polyethylene glycol (2000) monostearate (INCI; PEG-40 stearate) can be used.
- O / W emulsifiers glyceryl stearate citrate (CAS 39175-72-9, INCI Glyceryl Stearate Citrate, e.g. Imwitor 370 from Hüls), polyglyceryl-3 methylglucose distearate (INCI Polyglyceryl Methyl Glucose Distearate, e
- the emulsion according to the invention contains potassium cetyl phosphate, sodium cetearyl sulfate, sodium stearyl glutamate, alkali salts of saturated fatty acids of chain length C14-C22, in particular sodium stearate, as an anionic emulsifier.
- the emulsion according to the invention contains one or more polyglyceryl fatty acid esters as nonionic emulsifiers
- the polyglyceryl fatty acid ester particularly preferred according to the invention is polyglyceryl-10 stearate (INCI polyglyceryl-10 stearate).
- the emulsion according to the invention is characterized in that the content of one or more anionic emulsifiers in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.05 and 2% by weight, be particularly preferably between 0.1 and 1.0% by weight, based in each case on the total weight of the emulsion.
- the emulsion according to the invention is characterized in that the content of one or more nonionic emulsifiers, in particular one or more polyglyceryl fatty acid esters, especially polyglyceryl-10 stearate, in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.05 and
- the emulsion according to the invention can have the consistency of an ointment, cream or low-viscosity lotion or represent an ointment, cream or low-viscosity lotion.
- the process according to the invention is carried out in the form of the hot-hot process.
- a hot oil and water phase are combined with one another.
- the emulsion can advantageously be in the form of an ointment, cream or lotion (optionally sprayable).
- the emulsion can advantageously also be used as a spray or as an impregnation medium for a plaster or cloth. Therefore, plasters and tissues soaked with the emulsion according to the invention are also according to the invention.
- the water phase of the emulsion according to the invention can advantageously contain conventional cosmetic auxiliaries, such as alcohols, in particular those with a low carbon number, preferably ethanol and / or isopropanol, diols or polyols with a low carbon number, and their ethers, preferably propylene glycol, glycerol, ethylene glycol, ethylene glycol monoethyl - or monobutyl ether, hexanediol, octanediol, glyceryl caprylate, ethylhexylglycerol, methylpropanediol, propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether, and analogous products, as well as phenoxyethanol, benzene, benzyl alcohol, benzene, chloro-phenidones Foam stabilizers, electrolytes, self-tan
- the oil phase according to the invention can contain all conventional constituents of oil, fat and wax components used in cosmetics.
- the emulsion according to the invention can advantageously contain cosmetic active and care substances, for example the UV light protection filters approved according to the Cosmetics Ordinance.
- cosmetic active and care substances for example the UV light protection filters approved according to the Cosmetics Ordinance.
- active ingredients can advantageously be contained therein in concentrations of 0.01 to 30% by weight, based on the total weight of the preparation.
- the preparation according to the invention particularly preferably contains alpha-hydroxy acids and / or salts thereof as further constituents.
- lactic acid / lactates or citric acid / citrates are preferably used in a concentration of 0.01 to 5% by weight, based on the total weight of the preparation.
- the preparation according to the invention can contain perfumes in any desired composition and amount.
- the following examples are intended to illustrate the present invention without restricting it.
- the data always relate to% by weight, unless otherwise stated.
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- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to cosmetic oil-in-water emulsions (O/W emulsions) containing, in addition to a water phase, one or more oil phases dispersed therein and a) one or more anionic emulsifiers and/or b) one or more non-ionic emulsifiers and c) scleroglucane.
Description
Kosmetische O/W-Emulsion mit Skleroglucan Cosmetic O / W emulsion with scleroglucan
Die vorliegende Erfindung betrifft eine kosmetische Zubereitung enthaltend Skleroglucan. The present invention relates to a cosmetic preparation containing scleroglucan.
Der Wunsch, schön und attraktiv auszusehen, ist von Natur aus im Menschen verwurzelt. Auch wenn das Schönheitsideal im Laufe der Zeit Wandlungen erfahren hat, so ist das Stre ben nach einem makellosen Äußeren immer das Ziel der Menschen gewesen. Einen wesent lichen Anteil an einem schönen und attraktiven Äußeren haben dabei der Zustand und das Aussehen der Haut. The desire to look beautiful and attractive is inherently rooted in people. Even if the ideal of beauty has changed in the course of time, striving for a flawless appearance has always been the goal of people. The condition and appearance of the skin play a key role in a beautiful and attractive appearance.
Damit die Haut ihre biologischen Funktionen im vollen Umfang erfüllen kann, bedarf sie der regelmäßigen Reinigung und Pflege. Die Reinigung der Haut dient dabei der Entfernung von Schmutz, Schweiß und Resten abgestorbener Hautpartikel, die einen idealen Nährboden für Krankheitserreger und Parasiten aller Art bilden. Hautpflegeprodukte dienen meist der Be feuchtung und Rückfettung der Haut. Häufig sind ihnen Wirkstoffe zugesetzt, welche die Haut regenerieren und beispielsweise ihre vorzeitige Alterung (z. B. das Entstehen von Fält- chen, Falten) verhindern und vermindern sollen. In order for the skin to be able to fully fulfill its biological functions, it needs regular cleaning and care. The cleaning of the skin serves to remove dirt, sweat and residues of dead skin particles, which form an ideal breeding ground for pathogens and parasites of all kinds. Skin care products are mostly used to moisturize and re-oil the skin. Often, active ingredients are added to them that regenerate the skin and, for example, are intended to prevent and reduce its premature aging (eg the appearance of fine lines and wrinkles).
Hautpflegeprodukte bestehen in der Regel aus Emulsionen. Unter Emulsionen versteht man im Allgemeinen heterogene Systeme, die aus zwei nicht oder nur begrenzt miteinander mischbaren Flüssigkeiten bestehen, die üblicherweise als Phasen bezeichnet werden und bei denen eine der beiden Flüssigkeiten in Form feinster Tröpfchen in der anderen Flüssig keit dispergiert ist. Äußerlich und mit bloßem Auge betrachtet erscheinen Emulsionen homo gen. Skin care products are usually made up of emulsions. Emulsions are generally understood to mean heterogeneous systems which consist of two liquids which are immiscible or only partially miscible with one another, which are usually referred to as phases and in which one of the two liquids is dispersed in the other liquid in the form of very fine droplets. Externally and with the naked eye, emulsions appear homogeneous.
Sind die beiden Flüssigkeiten Wasser und Öl und liegen Öltröpfchen fein verteilt in Wasser vor, so handelt es sich um eine ÖI-in-Wasser-Emulsion (O/W-Emulsion, z. B. Milch). Der Grundcharakter einer O/W-Emulsion ist durch das Wasser geprägt. Bei einer Wasser-in-ÖI- Emulsion (W/O-Emulsion, z. B. Butter) handelt es sich um das umgekehrte Prinzip, wobei der Grundcharakter hier durch das Öl bestimmt wird.
Um Emulsionen über einen längeren Zeitraum stabil zu halten und eine Entmischung der Phasen zu verhindern, werden den Emulsionen sogenannte Emulgatoren zugesetzt. Bei Emulgatoren handelt es sich in der Regel um Moleküle mit einem polaren, hydrophilen Struk turelement und einem unpolaren, lipophilen Strukturelement. Ende der vierziger Jahre wurde ein System entwickelt, das die Auswahl von Emulgatoren erleichtern sollte. Jedem Emulga tor wird ein so genannter HLB-Wert (eine dimensionslose Zahl zwischen 0 und 20) zuge schrieben, der angibt, ob eine bevorzugte Wasser- oder Öllöslichkeit vorliegt. Zahlen unter 8 kennzeichnen öllösliche, hydrophobe Emulgatoren, Zahlen über 8 wasserlösliche, hydrophi le. If the two liquids are water and oil and if oil droplets are finely distributed in water, then it is an oil-in-water emulsion (O / W emulsion, e.g. milk). The basic character of an O / W emulsion is shaped by the water. In the case of a water-in-oil emulsion (W / O emulsion, e.g. butter), the principle is reversed, the basic character being determined here by the oil. In order to keep emulsions stable over a longer period of time and to prevent the phases from separating, so-called emulsifiers are added to the emulsions. Emulsifiers are usually molecules with a polar, hydrophilic structural element and a non-polar, lipophilic structural element. At the end of the 1940s a system was developed to make the selection of emulsifiers easier. A so-called HLB value (a dimensionless number between 0 and 20) is assigned to each emulsifier, which indicates whether the water or oil solubility is preferred. Numbers under 8 indicate oil-soluble, hydrophobic emulsifiers, numbers over 8 indicate water-soluble, hydrophilic emulsifiers.
Bei der Herstellung einer Emulsion wird die Wasserphase mit der Lipidphase (Ölphase) unter Rühren vereinigt, wobei die Tröpfchen der inneren Phase der Emulsion auf eine Größe von unter 10 pm zerkleinert werden müssen, damit die Emulsion stabil wird. In the production of an emulsion, the water phase is combined with the lipid phase (oil phase) with stirring, the droplets of the inner phase of the emulsion having to be broken down to a size of less than 10 μm so that the emulsion becomes stable.
Bei der Herstellung von O/W-Emulsionen mit hydrophilen Emulgatoren (Emulgatoren mit einem HLB-Wert von größer/gleich 8) tritt häufig das Problem auf, dass bei der Verwendung von überwiegend mittelpolaren bis polaren Lipiden in der Ölphase (d. h. Lipide mit einer Grenzflächenspannung gegen Wasser von kleiner als 30 mN/m) eine unerwünschte Pha senumkehr stattfinden kann. Ferner neigen derartige O/W-Emulsionen bei der Lagerung zur Phasenumkehr, d. h. die Zubereitungen sind häufig nicht besonders lagerstabil. When producing O / W emulsions with hydrophilic emulsifiers (emulsifiers with an HLB value of greater than / equal to 8), the problem often arises that when predominantly medium-polar to polar lipids are used in the oil phase (i.e. lipids with an interfacial tension against water of less than 30 mN / m) an undesirable phase reversal can take place. Furthermore, such O / W emulsions tend to reverse phase during storage; H. the preparations are often not particularly stable in storage.
Es war daher die Aufgabe der vorliegenden Erfindung, eine O/W-Emulsion mit hydrophilen Emulgatoren bzw. ein Herstellungsverfahren für eine O/W-Emulsion mit hydrophilen Emulga toren zu entwickeln, deren Neigung zur Phasenumkehr während der Herstellung und/oder Lagerung deutlich reduziert ist. It was therefore the object of the present invention to develop an O / W emulsion with hydrophilic emulsifiers or a production process for an O / W emulsion with hydrophilic emulsifiers whose tendency to phase inversion during production and / or storage is significantly reduced .
Überraschend gelöst wird die Aufgabe durch kosmetische ÖI-in-Wasser-Emulsionen (O/W- Emulsionen) enthaltend neben einer Wasserphase eine oder mehrere darin dispergierte Öl phasen sowie The object is surprisingly achieved by cosmetic oil-in-water emulsions (O / W emulsions) containing, in addition to a water phase, one or more oil phases dispersed therein as well
a) einen oder mehrere anionische Emulgatoren a) one or more anionic emulsifiers
und/oder and or
b) einen oder mehrere nichtionische Emulgatoren b) one or more nonionic emulsifiers
und and
c) Skleroglucan. c) scleroglucan.
Skleroglucan wird von Pilzarten der Gattung Sclerotium (Basidiomycota, Agariomycetes) als mikrobielles Exopolysaccharid in das umgebende Medium abgegeben. Sclerotium delphinii
beispielsweise ist ein bedeutender Pflanzenschädling. Skleroglucan wird auch als Scleroti umgummi (INCI: Sclerotium Gum) bezeichnet. Scleroglucan is released into the surrounding medium as a microbial exopolysaccharide by fungal species of the genus Sclerotium (Basidiomycota, Agariomycetes). Sclerotium delphinii for example is a major pest of plants. Scleroglucan is also known as Sclerotium Gum (INCI: Sclerotium Gum).
Skleroglucan ist ein (1— >3; 1— >6)-ß-D-Glucan. Seine mittlere Molmasse beträgt etwa 5,7 *106 g/mol, sein durchschnittlicher Polymerisationsgrad etwa 35.000. Scleroglucan is a (1—>3;1—> 6) -β-D-glucan. Its mean molar mass is about 5.7 * 10 6 g / mol, its average degree of polymerization about 35,000.
Die chemische Struktur des Skleroglucans wird wie folgt veranschaulicht: The chemical structure of scleroglucan is illustrated as follows:
Skleroglucan besteht aus einer linearen (1— >3)-ß-D-Glucan-Kette (OdHioOdOQHIOOd)^, an der statistisch jede dritte Glucose-Einheit mit einem einzelnen (1— >6)-ß-D-Glcp-Rest ver zweigt ist. Scleroglucan consists of a linear (1—> 3) -β-D-glucan chain (O d HioO d OQHIOOd) ^, on which statistically every third glucose unit with a single (1—> 6) -β-D- Glcp residue is branched.
Skleroglucan ist in Wasser gut löslich und kann als Verdicker eingesetzt werden. Der Einsatz von Skleroglucan in kosmetischen Emulsionen ist dem Fachmann an sich bekannt, doch konnte der Stand der Technik nicht den Weg zur vorliegenden Erfindung weisen. Scleroglucan is readily soluble in water and can be used as a thickener. The use of scleroglucan in cosmetic emulsions is known per se to the person skilled in the art, but the prior art could not point the way to the present invention.
Beispielsweise offenbart die DE 10 2014 015 554 die die Verwendung von Skleroglucan in UV-Filter enthaltenden kosmetischen Zubereitungen, zur Reduzierung der durch die UV- Filter in der Zubereitung hervorgerufenen Verunreinigung und/oder Verfärbung von Textilien. For example, DE 10 2014 015 554 discloses the use of scleroglucan in UV filters containing cosmetic preparations to reduce the contamination and / or discoloration of textiles caused by the UV filters in the preparation.
Die EP 1 132 076 beschreibt verdickte Haarzusammensetzungen mit einem Gehalt an Skleroglucan. EP 1 132 076 describes thickened hair compositions containing scleroglucan.
Es ist erfindungsgemäß vorteilhaft, wenn die erfindungsgemäße Emulsion dadurch gekenn zeichnet ist, dass der Gehalt an Skleroglucan in der Emulsion von 0,001 bis 5,0 Gew.-% und bevorzugt zwischen 0,01 und 1 ,5 Gew.-%, besonders bevorzugt zwischen 0, 1 und It is advantageous according to the invention if the emulsion according to the invention is characterized in that the content of scleroglucan in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.01 and 1.5% by weight, particularly preferably between 0, 1 and
1 ,0 Gew. %, jeweils bezogen auf das Gesamtgewicht der Emulsion, beträgt.
Es ist erfindungsgemäß vorteilhaft, wenn die die Emulsion einen oder mehrere Öl-in-Wasser- Emulgatoren (O/W-Emulgatoren) in einer Gesamtkonzentration von 0,05 bis 5,0 Gew.-% und bevorzugt in einer Gesamtkonzentration von 2,0 bis 4,0 Gew.-%, jeweils bezogen auf das Gesamtgewicht der Emulsion, beträgt. 1.0% by weight, based in each case on the total weight of the emulsion. According to the invention, it is advantageous if the emulsion contains one or more oil-in-water emulsifiers (O / W emulsifiers) in a total concentration of 0.05 to 5.0% by weight and preferably in a total concentration of 2.0 to 4.0% by weight, based in each case on the total weight of the emulsion.
Es ist erfindungsgemäß besonders vorteilhaft, wenn die erfindungsgemäße Emulsion dadurch gekennzeichnet ist, dass der Gehalt an einem oder mehreren anionischen Emulga toren in der Emulsion von 0,001 bis 5,0 Gew.-% und bevorzugt zwischen 0,05 und According to the invention it is particularly advantageous if the emulsion according to the invention is characterized in that the content of one or more anionic emulsifiers in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.05 and
2 Gew. %, besonders bevorzugt zwischen 0,1 und 1 ,0 Gew.-%, jeweils bezogen auf das Ge samtgewicht der Emulsion, beträgt. 2% by weight, particularly preferably between 0.1 and 1.0% by weight, based in each case on the total weight of the emulsion.
Es ist erfindungsgemäß besonders vorteilhaft, wenn die erfindungsgemäße Emulsion dadurch gekennzeichnet ist, dass der Gehalt an einem oder mehreren nichtionischen Emul gatoren in der Emulsion von 0,001 bis 5,0 Gew.-% und bevorzugt zwischen 0,05 und According to the invention it is particularly advantageous if the emulsion according to the invention is characterized in that the content of one or more nonionic emulsifiers in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.05 and
3 Gew.-%, besonders bevorzugt zwischen 0,1 und 2 Gew.-%, jeweils bezogen auf das Ge samtgewicht der Emulsion, beträgt. 3% by weight, particularly preferably between 0.1 and 2% by weight, in each case based on the total weight of the emulsion.
Es ist erfindungsgemäß vorteilhaft, wenn die erfindungsgemäße Emulsion dadurch gekenn zeichnet ist, dass als O/W-Emulgatoren hydrophile Emulgatoren mit einem HLB-Wert von größer/gleich 8 eingesetzt werden. Der HLB-Wert von Emulgatoren kann dabei den üblichen Standartwerken (z. B. Fiedler, Lexikon der Hilfsstoffe für Pharmazie, Kosmetik und angren zende Gebiete, Editio Cantor Verlag, Aulendorf) entnommen werden. It is advantageous according to the invention if the emulsion according to the invention is characterized in that hydrophilic emulsifiers with an HLB value of greater than or equal to 8 are used as O / W emulsifiers. The HLB value of emulsifiers can be found in the usual standard works (e.g. Fiedler, Lexicon of Auxiliaries for Pharmacy, Cosmetics and Neighboring Areas, Editio Cantor Verlag, Aulendorf).
Es ist erfindungsgemäß bevorzugt, wenn die erfindungsgemäße Emulsion dadurch gekenn zeichnet ist, dass als O/W-Emulgatoren Glycerylstearatcitrat (CAS 39175-72-9, INCI Glyceryl Stearate Citrate, z. B. Imwitor 370 der Firma Hüls), Polyglyceryl-3 Methylglucosedistearat (INCI Polyglyceryl Methyl Glucose Distearate, z. B. Tego Care 450 der Firma Evonik) und/oder Polyethylenglycol(2000)monostearat (INCI; PEG-40 stearate) eingesetzt werden. It is preferred according to the invention if the emulsion according to the invention is characterized in that, as O / W emulsifiers, glyceryl stearate citrate (CAS 39175-72-9, INCI Glyceryl Stearate Citrate, e.g. Imwitor 370 from Hüls), polyglyceryl-3 methylglucose distearate (INCI Polyglyceryl Methyl Glucose Distearate, e.g. Tego Care 450 from Evonik) and / or polyethylene glycol (2000) monostearate (INCI; PEG-40 stearate) can be used.
In einer erfindungsgemäß bevorzugten Ausführungsform enthält die erfindungsgemäße Emulsion Kalium Cetylphosphat, Natrium Cetearylsulfat, Natrium Stearylglutamat, Alkalisal ze von gesättigten Fettsäuren der Kettenlänge C14-C22, insbesondere Natrium Stearat als anionischen Emulgator. In a preferred embodiment according to the invention, the emulsion according to the invention contains potassium cetyl phosphate, sodium cetearyl sulfate, sodium stearyl glutamate, alkali salts of saturated fatty acids of chain length C14-C22, in particular sodium stearate, as an anionic emulsifier.
In einer weiteren erfindungsgemäß bevorzugten Ausführungsform enthält die erfindungsge mäße Emulsion einen oder mehrere Polyglycerylfettsäureester als nichtionische Emulgato-
ren. Der erfindungsgemäß besonders bevorzugte Polyglycerylfettsäureester ist dabei Poly- glyceryl-10 Stearat (INCI Polyglyceryl-10 Stearate). In a further embodiment preferred according to the invention, the emulsion according to the invention contains one or more polyglyceryl fatty acid esters as nonionic emulsifiers The polyglyceryl fatty acid ester particularly preferred according to the invention is polyglyceryl-10 stearate (INCI polyglyceryl-10 stearate).
Es ist erfindungsgemäß besonders vorteilhaft, wenn die erfindungsgemäße Emulsion dadurch gekennzeichnet ist, dass der Gehalt an ein oder mehreren anionischen Emulgatoren in der Emulsion von 0,001 bis 5,0 Gew.-% und bevorzugt zwischen 0,05 und 2 Gew.-%, be sonders bevorzugt zwischen 0,1 und 1 ,0 Gew.-%, jeweils bezogen auf das Gesamtgewicht der Emulsion, beträgt. According to the invention, it is particularly advantageous if the emulsion according to the invention is characterized in that the content of one or more anionic emulsifiers in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.05 and 2% by weight, be particularly preferably between 0.1 and 1.0% by weight, based in each case on the total weight of the emulsion.
Es ist erfindungsgemäß besonders vorteilhaft, wenn die erfindungsgemäße Emulsion dadurch gekennzeichnet ist, dass der Gehalt an ein oder mehreren nichtionischen Emulgato ren, insbesondere einen oder mehrere Polyglycerylfettsäureester, besonders Polyglyceryl-10 Stearat in der Emulsion von 0,001 bis 5,0 Gew.-% und bevorzugt zwischen 0,05 und According to the invention, it is particularly advantageous if the emulsion according to the invention is characterized in that the content of one or more nonionic emulsifiers, in particular one or more polyglyceryl fatty acid esters, especially polyglyceryl-10 stearate, in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.05 and
3 Gew.-%, besonders bevorzugt zwischen 0,1 und 2,0 Gew.-%, jeweils bezogen auf das Gesamtgewicht der Emulsion, beträgt. 3% by weight, particularly preferably between 0.1 and 2.0% by weight, based in each case on the total weight of the emulsion.
Die erfindungsgemäße Emulsion kann die Konsistenz einer Salbe, Creme oder dünnflüssi gen Lotion aufweisen bzw. eine Salbe, Creme oder dünnflüssige Lotion darstellen. The emulsion according to the invention can have the consistency of an ointment, cream or low-viscosity lotion or represent an ointment, cream or low-viscosity lotion.
Es ist erfindungsgemäß bevorzugt, wenn das erfindungsgemäße Verfahren in Form des Hot- Hot-Verfahrens durchgeführt wird. Bei diesem Verfahren werden eine heiße Öl- und Was serphase miteinander vereinigt. It is preferred according to the invention if the process according to the invention is carried out in the form of the hot-hot process. In this process, a hot oil and water phase are combined with one another.
Dabei ist es erfindungsgemäß besonders bevorzugt, wenn das Verfahren bei einer Tempera tur nicht über 85 °C durchgeführt wird. It is particularly preferred according to the invention if the process is carried out at a temperature not above 85.degree.
Die Emulsion kann erfindungsgemäß vorteilhaft als Salbe, Creme oder Lotion (ggf. sprühbar) vorliegen. According to the invention, the emulsion can advantageously be in the form of an ointment, cream or lotion (optionally sprayable).
Die Emulsion kann erfindungsgemäß vorteilhaft auch als Spray oder als Tränkungsmedium für ein Pflaster oder T uch eingesetzt werden. Daher sind auch Pflaster und Tücher getränkt mit der erfindungsgemäßen Emulsion, erfindungsgemäß. According to the invention, the emulsion can advantageously also be used as a spray or as an impregnation medium for a plaster or cloth. Therefore, plasters and tissues soaked with the emulsion according to the invention are also according to the invention.
Die Wasserphase der erfindungsgemäßen Emulsion kann vorteilhaft übliche kosmetische Hilfsstoffe enthalten, wie beispielsweise Alkohole, insbesondere solche niedriger C-Zahl, vorzugsweise Ethanol und/oder Isopropanol, Diole oder Polyole niedriger C-Zahl sowie de ren Ether, vorzugsweise Propylenglykol, Glycerin, Ethylenglykol, Ethylenglykolmonoethyl-
oder -monobutylether, Hexandiol, Octandiol, Glycerylcaprylat, Ethylhexylglycerin, Methylpro- pandiol, Propylenglykolmonomethyl, -monoethyl- oder -monobutylether, Diethylenglykolmo- nomethyl- oder monoethylether, und analoge Produkte, außerdem Phenoxyethanol, Hydro- xyacetophenone, Benzylalkohol, Benzethonium Chlorid, Polymere, Schaumstabilisatoren, Elektrolyte, Selbstbräuner, Repellentien sowie insbesondere ein oder mehrere Verdickungs mittel, welches oder welche vorteilhaft gewählt werden können aus der Gruppe der Polysac charide bzw. deren Derivate, z.B. Xanthangummi, Carrageenan, Gellangummi, Stärken und Cellulosen, Hyaluronsäure. The water phase of the emulsion according to the invention can advantageously contain conventional cosmetic auxiliaries, such as alcohols, in particular those with a low carbon number, preferably ethanol and / or isopropanol, diols or polyols with a low carbon number, and their ethers, preferably propylene glycol, glycerol, ethylene glycol, ethylene glycol monoethyl - or monobutyl ether, hexanediol, octanediol, glyceryl caprylate, ethylhexylglycerol, methylpropanediol, propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether, and analogous products, as well as phenoxyethanol, benzene, benzyl alcohol, benzene, chloro-phenidones Foam stabilizers, electrolytes, self-tanners, repellants and, in particular, one or more thickeners, which can advantageously be selected from the group of polysaccharides or their derivatives, for example xanthan gum, carrageenan, gellan gum, starches and celluloses, hyaluronic acid.
Die erfindungsgemäße Ölphase kann alle herkömmlichen Bestandteile von in der Kosmetik eingesetzten Öl-, Fett- und Wachskomponenten enthalten. The oil phase according to the invention can contain all conventional constituents of oil, fat and wax components used in cosmetics.
Die erfindungsgemäße Emulsion kann erfindungsgemäß vorteilhaft kosmetische Wirk- und Pflegestoffe enthalten, beispielsweise die nach der Kosmetikverordnung zugelassenen UV- Lichtschutzfilter. Derartige Wirkstoffe können erfindungsgemäß vorteilhaft in Konzentrationen von 0,01 bis 30 Gew.-%, bezogen auf das Gesamtgewicht der Zubereitung in dieser enthal ten sein. According to the invention, the emulsion according to the invention can advantageously contain cosmetic active and care substances, for example the UV light protection filters approved according to the Cosmetics Ordinance. According to the invention, such active ingredients can advantageously be contained therein in concentrations of 0.01 to 30% by weight, based on the total weight of the preparation.
Als weitere Pflegestoffe können insbesondere Niacinamid, Panthenol, Aloe vera, Vitamin E, Tocopherylacetat, Vitamin A, Vitamin A-Derivate, Retinylpalmitat, Vitamin C, Vitamin C- Derivate, Ascorbylphosphat, Ascorbylglucosid, Harnstoff, Taurin, Folsäure, Aminosäuren (z.B. Glycin, Histidin, Alanin, Arginin), Carnosin, ungesättigte Fettsäuren und deren Ester, insbesondere Di- und Triglyceride (z.B. g-Linolensäure, Linolsäure, Ölsäure), Mannose, Magnolia Rindenextrakt, Magnolol, Honokiol, Allantoin, Algenextrakte, Glycyrrhetinsäure Konzentrationen von 0,001 bis 5 Gew.-%, bezogen auf das Gesamtgewicht der Zubereitung eingesetzt werden. As further care substances, niacinamide, panthenol, aloe vera, vitamin E, tocopheryl acetate, vitamin A, vitamin A derivatives, retinyl palmitate, vitamin C, vitamin C derivatives, ascorbyl phosphate, ascorbyl glucoside, urea, taurine, folic acid, amino acids (e.g. glycine, Histidine, alanine, arginine), carnosine, unsaturated fatty acids and their esters, especially di- and triglycerides (e.g. g-linolenic acid, linoleic acid, oleic acid), mannose, magnolia bark extract, magnolol, honokiol, allantoin, algae extracts, glycyrrhetinic acid concentrations of 0.001 to 5 % By weight, based on the total weight of the preparation, are used.
Erfindungsgemäß besonders bevorzugt enthält die erfindungsgemäße Zubereitung als weite re Bestandteile Alpha-Hydroxysäuren und/oder deren Salze. Dabei werden erfindungsgemäß bevorzugt Milchsäure/Lactate oder Zitronensäure/Citrate in einer Konzentration von 0,01 bis 5 Gew.-%, bezogen auf das Gesamtgewicht der Zubereitung eingesetzt. According to the invention, the preparation according to the invention particularly preferably contains alpha-hydroxy acids and / or salts thereof as further constituents. According to the invention, lactic acid / lactates or citric acid / citrates are preferably used in a concentration of 0.01 to 5% by weight, based on the total weight of the preparation.
Die erfindungsgemäße Zubereitung kann Parfümstoffe in beliebiger Zusammensetzung und Menge enthalten.
Die nachfolgenden Beispiele sollen die vorliegende Erfindung verdeutlichen ohne sie einzu schränken. Die Angaben beziehen sich stets auf Gew.-%, sofern nicht andere Angaben ge macht werden.
The preparation according to the invention can contain perfumes in any desired composition and amount. The following examples are intended to illustrate the present invention without restricting it. The data always relate to% by weight, unless otherwise stated.
Rezepturbeispiele: Recipe examples:
pH 6
pH 6
pH 6
pH 6
pH 5,2
pH 5.2
pH 5, 0-5, 5
pH 5.0-5.5
pH 5-6
pH 5-6
Claims
1. Kosmetische ÖI-in-Wasser-Emulsionen (O/W-Emulsionen) enthaltend neben einer Wasserphase eine oder mehrere darin dispergierte Ölphasen sowie 1. Cosmetic oil-in-water emulsions (O / W emulsions) containing one or more oil phases dispersed therein in addition to a water phase
a) einen oder mehrere anionische Emulgatoren a) one or more anionic emulsifiers
und/oder and or
b) einen oder mehrere nichtionische Emulgatoren b) one or more nonionic emulsifiers
und and
c) Skleroglucan. c) scleroglucan.
2. O/W-Emulsionen nach Anspruch 1 , dadurch gekennzeichnet, dass der Gehalt an 2. O / W emulsions according to claim 1, characterized in that the content of
Skleroglucan in der Emulsion von 0,01 bis 1 ,0 Gew.-%, bezogen auf das Gesamtge wicht der Emulsion, beträgt. Scleroglucan in the emulsion from 0.01 to 1, 0 wt .-%, based on the total weight of the emulsion is.
3. O/W-Emulsionen nach Anspruch 1 oder 2, dadurch gekennzeichnet, dass die Emulsion einen oder mehrere ÖI-in-Wasser-Emulgatoren (O/W-Emulgatoren) in einer Gesamt konzentration von 0,05 bis 5,0%, bezogen auf das Gesamtgewicht der Emulsion, be trägt. 3. O / W emulsions according to claim 1 or 2, characterized in that the emulsion has one or more oil-in-water emulsifiers (O / W emulsifiers) in a total concentration of 0.05 to 5.0%, based on the total weight of the emulsion, be.
4. O/W-Emulsionen nach einem der vorstehenden Ansprüche, dadurch gekennzeichnet, dass der Gehalt an einem oder mehreren anionischen Emulgatoren in der Emulsion von 0,001 bis 5,0 Gew.-% und bevorzugt zwischen 0,05 und 2 Gew.-%, besonders be vorzugt zwischen 0,1 und 1 ,0 Gew.-%, jeweils bezogen auf das Gesamtgewicht der Emulsion, beträgt. 4. O / W emulsions according to one of the preceding claims, characterized in that the content of one or more anionic emulsifiers in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.05 and 2% by weight , particularly preferably between 0.1 and 1.0% by weight, based in each case on the total weight of the emulsion.
5. O/W-Emulsionen nach einem der vorstehenden Ansprüche, dadurch gekennzeichnet, dass der Gehalt an einem oder mehreren nichtionischen Emulgatoren in der Emulsion von 0,001 bis 5,0 Gew.-% und bevorzugt zwischen 0,05 und 3 Gew.-%, besonders be vorzugt zwischen 0,1 und 2,0 Gew.-%, jeweils bezogen auf das Gesamtgewicht der Emulsion, beträgt. 5. O / W emulsions according to one of the preceding claims, characterized in that the content of one or more nonionic emulsifiers in the emulsion is from 0.001 to 5.0% by weight and preferably between 0.05 and 3% by weight , particularly preferably between 0.1 and 2.0% by weight, based in each case on the total weight of the emulsion.
6. O/W-Emulsionen nach einem der vorstehenden Ansprüche, dadurch gekennzeichnet, dass als O/W-Emulgatoren hydrophile Emulgatoren mit einem HLB-Wert von grö ßer/gleich 8 eingesetzt werden. 6. O / W emulsions according to one of the preceding claims, characterized in that hydrophilic emulsifiers with an HLB value of greater than or equal to 8 are used as O / W emulsifiers.
7. O/W-Emulsionen nach einem der vorstehenden Ansprüche, dadurch gekennzeichnet, dass als O/W-Emulgatoren Polyglyceryl-3 Methylglucosedistearat (INCI Polyglyceryl
Methyl Glucose Distearate, z. B. Tego Care 450 der Firma Evonik), Kalium Cetylphos- phate, Natrium Cetearylsulfat, Natrium Stearylglutamat, Kalium Cetylphosphate, Alkali salze von gesättigten Fettsäuren der Kettenlänge C14-C22, insbesondere Natrium Stearat und/oder Polyethylenglycol(2000)monostearat (INCI; PEG-40 stearate) einge setzt werden. 7. O / W emulsions according to one of the preceding claims, characterized in that the O / W emulsifiers are polyglyceryl-3 methylglucose distearate (INCI polyglyceryl Methyl glucose distearate, e.g. B. Tego Care 450 from Evonik), potassium cetyl phosphate, sodium cetearyl sulfate, sodium stearyl glutamate, potassium cetyl phosphate, alkali salts of saturated fatty acids of chain length C14-C22, especially sodium stearate and / or polyethylene glycol (2000) monostearate (INCI; PEG -40 stearate) can be used.
8. O/W-Emulsionen nach einem der vorstehenden Ansprüche, dadurch gekennzeichnet, dass als O/W-Emulgatoren ein oder mehrere Polyglycerylfettsäureester gewählt wer den, insbesondere bevorzugt Polyglyceryl-10 Stearat.
8. O / W emulsions according to any one of the preceding claims, characterized in that one or more polyglyceryl fatty acid esters are selected as O / W emulsifiers, particularly preferably polyglyceryl-10 stearate.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102019207777.3A DE102019207777A1 (en) | 2019-05-28 | 2019-05-28 | Cosmetic O / W emulsion with scleroglucan |
PCT/EP2020/062968 WO2020239401A1 (en) | 2019-05-28 | 2020-05-11 | Cosmetic oil-in-water emulsion containing scleroglucane |
Publications (1)
Publication Number | Publication Date |
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EP3962433A1 true EP3962433A1 (en) | 2022-03-09 |
Family
ID=70682841
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Application Number | Title | Priority Date | Filing Date |
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EP20725688.4A Pending EP3962433A1 (en) | 2019-05-28 | 2020-05-11 | Cosmetic oil-in-water emulsion containing scleroglucane |
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EP (1) | EP3962433A1 (en) |
DE (1) | DE102019207777A1 (en) |
WO (1) | WO2020239401A1 (en) |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
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FR2805990B1 (en) | 2000-03-07 | 2003-04-11 | Oreal | THICKENED HAIR COMPOSITION COMPRISING A FIXING POLYMER AND A POWDER COMPOUND |
DE102008028822A1 (en) * | 2007-06-20 | 2009-02-19 | Henkel Ag & Co. Kgaa | Cosmetic stick composition for application to the skin for treating acne, pimples, blackhead and cellulitis, and for skin tightening, comprises wax component, polymeric organic hydrogel forming substance and nonionic oil in water emulgent |
KR20100099285A (en) * | 2007-12-14 | 2010-09-10 | 바스프 에스이 | Sunscreen compositions comprising colour pigments |
DE112012002397B4 (en) * | 2011-06-07 | 2019-10-31 | Beiersdorf Ag | Cosmetic or dermatological preparations with polyglyceryl-10-stearate and polylysine |
FR2983065B1 (en) * | 2011-11-25 | 2014-06-27 | Oreal | TINTED EMULSION |
FR2987260B1 (en) * | 2012-02-23 | 2014-02-28 | Oreal | FOAM COMPOSITION COMPRISING OIL-IN-WATER EMULSION COMPRISING HYDROPHOBIC SILICA AEROGEL PARTICLES |
US20140004058A1 (en) * | 2012-06-28 | 2014-01-02 | Johnson & Johnson Consumer Companies, Inc. | Sunscreen compositions containing an ultraviolet radiation-absorbing polyester |
US9949902B2 (en) * | 2012-06-29 | 2018-04-24 | Kimberly-Clark Worldwide, Inc. | Stable emulsion for prevention of skin irritation and items using same |
ES2718335T3 (en) * | 2013-06-03 | 2019-07-01 | Oreal | Cosmetic compositions comprising an associative polyurethane and a hydrophobic coated pigment |
CN105491991B (en) * | 2013-10-29 | 2019-07-19 | 玫琳凯有限公司 | Cosmetic composition |
DE102014015554A1 (en) * | 2014-10-22 | 2016-04-28 | Beiersdorf Ag | Polysaccharide-containing sunscreens with reduced tendency to textile staining |
JP2016117666A (en) * | 2014-12-19 | 2016-06-30 | ロレアル | Non-adhesive stable composition |
FR3060979B1 (en) * | 2016-12-22 | 2020-06-12 | L'oreal | OIL-IN-WATER EMULSION COMPRISING A PARTICULAR SURFACTANT SYSTEM |
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- 2019-05-28 DE DE102019207777.3A patent/DE102019207777A1/en not_active Withdrawn
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