EP3891306C0 - Biomarker zum nachweiss eines zearalenon effekts - Google Patents

Biomarker zum nachweiss eines zearalenon effekts

Info

Publication number
EP3891306C0
EP3891306C0 EP19821052.8A EP19821052A EP3891306C0 EP 3891306 C0 EP3891306 C0 EP 3891306C0 EP 19821052 A EP19821052 A EP 19821052A EP 3891306 C0 EP3891306 C0 EP 3891306C0
Authority
EP
European Patent Office
Prior art keywords
zearalenone
biomarker
detect
effect
zearalenone effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP19821052.8A
Other languages
English (en)
French (fr)
Other versions
EP3891306B1 (de
EP3891306A2 (de
Inventor
Bertrand Grenier
Veronika Nagl
Gerd Schatzmayr
Eva-Maria Binder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Austria GmbH
Original Assignee
DSM Austria GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM Austria GmbH filed Critical DSM Austria GmbH
Publication of EP3891306A2 publication Critical patent/EP3891306A2/de
Application granted granted Critical
Publication of EP3891306B1 publication Critical patent/EP3891306B1/de
Publication of EP3891306C0 publication Critical patent/EP3891306C0/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/166Oligonucleotides used as internal standards, controls or normalisation probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/178Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06NCOMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N3/00Computing arrangements based on biological models
    • G06N3/12Computing arrangements based on biological models using genetic models
    • G06N3/123DNA computing
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00ICT specially adapted for sequence analysis involving nucleotides or amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP19821052.8A 2018-12-06 2019-12-06 Biomarker zum nachweiss eines zearalenon effekts Active EP3891306B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18210684.9A EP3663413A1 (de) 2018-12-06 2018-12-06 Biomarker zum nachweiss eines zearalenon effekts
PCT/EP2019/083953 WO2020115270A2 (en) 2018-12-06 2019-12-06 Biomarker

Publications (3)

Publication Number Publication Date
EP3891306A2 EP3891306A2 (de) 2021-10-13
EP3891306B1 EP3891306B1 (de) 2025-02-26
EP3891306C0 true EP3891306C0 (de) 2025-02-26

Family

ID=64745873

Family Applications (2)

Application Number Title Priority Date Filing Date
EP18210684.9A Withdrawn EP3663413A1 (de) 2018-12-06 2018-12-06 Biomarker zum nachweiss eines zearalenon effekts
EP19821052.8A Active EP3891306B1 (de) 2018-12-06 2019-12-06 Biomarker zum nachweiss eines zearalenon effekts

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EP18210684.9A Withdrawn EP3663413A1 (de) 2018-12-06 2018-12-06 Biomarker zum nachweiss eines zearalenon effekts

Country Status (5)

Country Link
US (1) US20220002806A1 (de)
EP (2) EP3663413A1 (de)
CN (1) CN113474467B (de)
BR (1) BR112021010617A2 (de)
WO (1) WO2020115270A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111455044B (zh) * 2020-06-10 2023-05-23 新疆农垦科学院 一种用于母羊早期妊娠诊断的外泌体miRNA标志物及其应用
CN114878559B (zh) * 2022-05-05 2024-05-14 川北医学院 一种裸眼检测中药材和食品中玉米赤霉烯酮的方法
CN115975982B (zh) * 2023-02-24 2025-09-23 河南农业大学 GhZH蛋白在高效水解玉米赤霉烯酮及其代谢衍生物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8574838B2 (en) * 2010-07-14 2013-11-05 University Of Medicine And Dentistry Of New Jersey Methods and kits for miRNA isolation and quantitation
CN107915774B (zh) * 2017-07-26 2021-02-05 华中农业大学 用于检测玉米赤霉烯酮及其代谢产物的单抗及酶联免疫方法与试剂盒

Also Published As

Publication number Publication date
US20220002806A1 (en) 2022-01-06
EP3891306B1 (de) 2025-02-26
CN113474467B (zh) 2024-09-13
EP3663413A1 (de) 2020-06-10
CN113474467A (zh) 2021-10-01
EP3891306A2 (de) 2021-10-13
BR112021010617A2 (pt) 2021-08-24
WO2020115270A3 (en) 2020-07-23
WO2020115270A2 (en) 2020-06-11

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