EP3886650A1 - Laboratoire modulaire deployable par champ mobile pour la detection et l'analyse rapides sur place de cibles biologiques - Google Patents

Laboratoire modulaire deployable par champ mobile pour la detection et l'analyse rapides sur place de cibles biologiques

Info

Publication number
EP3886650A1
EP3886650A1 EP19881358.6A EP19881358A EP3886650A1 EP 3886650 A1 EP3886650 A1 EP 3886650A1 EP 19881358 A EP19881358 A EP 19881358A EP 3886650 A1 EP3886650 A1 EP 3886650A1
Authority
EP
European Patent Office
Prior art keywords
workbench
mobile
laboratory
cavity
backpack
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19881358.6A
Other languages
German (de)
English (en)
Other versions
EP3886650A4 (fr
Inventor
Jonathan L. JACOBS
Joseph A. Russell
Jacob R. ASPINWALL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MRIGlobal Inc
Original Assignee
MRIGlobal Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/185,178 external-priority patent/US11400454B2/en
Application filed by MRIGlobal Inc filed Critical MRIGlobal Inc
Publication of EP3886650A1 publication Critical patent/EP3886650A1/fr
Publication of EP3886650A4 publication Critical patent/EP3886650A4/fr
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45C—PURSES; LUGGAGE; HAND CARRIED BAGS
    • A45C5/00—Rigid or semi-rigid luggage
    • A45C5/03—Suitcases
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45C—PURSES; LUGGAGE; HAND CARRIED BAGS
    • A45C5/00—Rigid or semi-rigid luggage
    • A45C5/14—Rigid or semi-rigid luggage with built-in rolling means
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45C—PURSES; LUGGAGE; HAND CARRIED BAGS
    • A45C9/00—Purses, Luggage or bags convertible into objects for other use
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45F—TRAVELLING OR CAMP EQUIPMENT: SACKS OR PACKS CARRIED ON THE BODY
    • A45F3/00—Travelling or camp articles; Sacks or packs carried on the body
    • A45F3/04—Sacks or packs carried on the body by means of two straps passing over the two shoulders
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45F—TRAVELLING OR CAMP EQUIPMENT: SACKS OR PACKS CARRIED ON THE BODY
    • A45F4/00—Travelling or camp articles which may be converted into other articles or into objects for other use; Sacks or packs carried on the body and convertible into other articles or into objects for other use
    • A45F4/02—Sacks or packs convertible into other articles or into objects for other use
    • A—HUMAN NECESSITIES
    • A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47B—TABLES; DESKS; OFFICE FURNITURE; CABINETS; DRAWERS; GENERAL DETAILS OF FURNITURE
    • A47B3/00—Folding or stowable tables
    • A47B3/10—Travelling or trunk tables
    • A—HUMAN NECESSITIES
    • A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47B—TABLES; DESKS; OFFICE FURNITURE; CABINETS; DRAWERS; GENERAL DETAILS OF FURNITURE
    • A47B31/00—Service or tea tables, trolleys, or wagons
    • A47B31/02—Service or tea tables, trolleys, or wagons with heating, cooling or ventilating means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00—Enclosures; Chambers
    • B01L1/52—Transportable laboratories; Field kits
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/02—Laboratory benches or tables; Fittings therefor
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45C—PURSES; LUGGAGE; HAND CARRIED BAGS
    • A45C5/00—Rigid or semi-rigid luggage
    • A45C5/03—Suitcases
    • A45C2005/037—Suitcases with a hard shell, i.e. rigid shell as volume creating element
    • A—HUMAN NECESSITIES
    • A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47B—TABLES; DESKS; OFFICE FURNITURE; CABINETS; DRAWERS; GENERAL DETAILS OF FURNITURE
    • A47B37/00—Tables adapted for other particular purposes
    • A47B2037/005—Tables specially adapted for laboratories
    • A—HUMAN NECESSITIES
    • A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
    • A47B—TABLES; DESKS; OFFICE FURNITURE; CABINETS; DRAWERS; GENERAL DETAILS OF FURNITURE
    • A47B2200/00—General construction of tables or desks
    • A47B2200/008—Tables or desks having means for applying electronic or electric devices
    • A47B2200/0081—Auxiliary apparatus with electrical connections for office furniture

Definitions

  • qPCR quantitative Polymerase chain reaction
  • Fig. 16 is a schematic diagram of the specific protocol used in the field testing in the Florida Everglades associated with Fig. 15.
  • Fig. 18 is a perspective view of the footlocker laboratory of Fig. 17 shown in its packed or closed condition.
  • Fig. 21 is a perspective view of the field-deployable footlocker laboratory of Figs. 19 and 20 shown in its fully deployed configuration.
  • Fig. 22 is a perspective view similar to Fig. 21 illustrating another embodiment of the keyboard tabletop portion of the deployed workbench station.
  • the DNA sequencing system 32 can be the Oxford Nanopore Minion Mkl system which is a hand-held next generation system which is simple to use and produces rapid turnaround time, less than 3 hours, for direct sequencing of either amplicon or whole-sample DNA/RNA.
  • the mobile bioinformatics analysis system 26 can be the Intel NUC system which is an ultra-compact, cloud-enabled mobile system which provides local data storage and bioinformatics analysis of sequencing data using a custom bioinformatics pipeline.
  • Fig. 6 is a representative flow chart illustrating one protocol for using the present backpack 10 in the field. Once an operator arrives at the specific field location, traps or other methods are typically set up and/or used for initial capture of the particular pathogen, virus and/or bacteria targeted at step 34 in Fig. 6. This could include blood samples, forensic swabs, soil water plant or animal tissue.
  • the present system 10 is designed to identify the specific virus, pathogen and/or bacteria targeted within two hours and identification of the specific virus, pathogen and/or bacteria genetic sequence can be accomplished within six hours. These times may vary depending upon the particular equipment utilized and the specific targeted virus, pathogen and/or bacteria.
  • the present backpack laboratory 10 successfully extracted, amplified, sequenced and characterized viral RNA from a mosquito-pool sample.
  • the protocol used can be run end to end with the total consumables and hardware foot print packed within the present backpack 10 or 46.
  • Basic protocol used in the Florida Everglades test is set forth in Fig. 16.
  • the present backpack laboratory produced sample to answer, including actionable bioinformatics reports, in less than 6 hours. This is presented as an example use-case of the present backpack laboratory and the below discussed footlocker laboratory.
  • the footlocker lid member 84 likewise includes a plurality of power outlets such as outlets 106, 108, 110 and 112 illustrated in Fig. 17 for powering still additional equipment needed for the detection, sequencing and analysis of the targeted agents and toxins.
  • These power outlets can be USB3 and/or standard Nema 5-15 type B power outlets.
  • Fig. 22 and the corresponding space 164 located in the second footlocker member 134 above workbench 144 can likewise be similarly configured as best shown in Fig. 22 for again storing and housing required components for accomplishing the detection, amplification, sequencing and analysis of various specific viruses, pathogens, bacteria and other diseases accumulated in the field, or for other desired purposes including equipment and technology for human identification using DNA traces.
  • backpack member 166 has an overall profile no greater than compartments 138, 140 and 142 as illustrated.
  • the second footlocker member 134 likewise includes a lower internal space or cavity 190 as best illustrated in Figs. 20 and 23 which is configured to at least partially receive compartments 138, 140 and 142 as well as workbench 144 when positioned in its collapsed and stored position as shown in Figs. 20 and 23 when the second footlocker member 134 is moved to its closed position as illustrated in Fig. 19.
  • backpack member 166 can likewise hold a lot of the same ancillary equipment including pipettes, reagent bottles, tube racks and other consumables necessary for a particular application as previously explained with respect to mobile laboratories 10, 46 and 80 including a PCR system and a DNA/RNA sequencing system.
  • Windshield member 174 can be stored within the field-deployable footlocker laboratory 130 adjacent workbench portion 150 in its stored position as best illustrated in Fig. 20 or it can be conveniently stored, attached or otherwise held either within the lower cavity 190 of the second footlocker member 134 or under workbench table top member 148 via straps, Velcro atachment means, or other suitable holding mechanisms.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Un laboratoire modulaire déployable par un champ mobile permet de détecter, de séquencer et d'analyser plus commodément des agents biologiques au niveau au point de besoin. Ce dispositif permet aux opérateurs de terrain de passer par un échantillon à des informations exploitables dans le domaine sans avoir besoin d'une connexion internet ou d'une alimentation à base de grille. Le présent laboratoire mobile est configuré dans une configuration de casier comprenant une pluralité de compartiments différents spécifiquement configurés pour contenir l'ensemble de l'équipement nécessaire pour une utilisation dans une grande variété d'applications différentes, notamment l'extraction, l'amplification, le séquençage et la caractérisation de virus spécifiques, d'agents pathogènes et d'autres bactéries directement dans le domaine comprenant une alimentation électrique intégrée pour fournir de l'énergie aux composants pertinents jusqu'à 72 heures d'utilisation continue sans avoir besoin d'une quelconque source d'alimentation externe. Le présent laboratoire mobile comprend une zone d'établi déployable qui fournit un poste de travail stable lorsque la configuration de casier est déployée.
EP19881358.6A 2018-11-09 2019-11-08 Laboratoire modulaire deployable par champ mobile pour la detection et l'analyse rapides sur place de cibles biologiques Pending EP3886650A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16/185,178 US11400454B2 (en) 2017-01-10 2018-11-09 Modular mobile field-deployable laboratory for rapid, on-site detection and analysis of biological targets
PCT/US2019/060464 WO2020097459A1 (fr) 2018-11-09 2019-11-08 Laboratoire modulaire deployable par champ mobile pour la detection et l'analyse rapides sur place de cibles biologiques

Publications (2)

Publication Number Publication Date
EP3886650A1 true EP3886650A1 (fr) 2021-10-06
EP3886650A4 EP3886650A4 (fr) 2022-10-19

Family

ID=70611311

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19881358.6A Pending EP3886650A4 (fr) 2018-11-09 2019-11-08 Laboratoire modulaire deployable par champ mobile pour la detection et l'analyse rapides sur place de cibles biologiques

Country Status (3)

Country Link
EP (1) EP3886650A4 (fr)
GB (2) GB2606967B (fr)
WO (1) WO2020097459A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022099134A1 (fr) * 2020-11-06 2022-05-12 Touria LTD Solution de poste de travail portatif et modulaire

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3532370A1 (de) * 1985-09-11 1987-03-19 Lasis Handelsgesellschaft Mbh Medizinisch-diagnostisches untersuchungslabor
RU2056944C1 (ru) * 1992-12-30 1996-03-27 Государственный научно-исследовательский институт биологического приборостроения Переносной комплект для лабораторных исследований
US5429432A (en) * 1994-04-25 1995-07-04 Johnson; Rodney L. Collapsible playroom
DE29600640U1 (de) * 1996-01-16 1996-09-12 Reuter, Susanne, 85072 Eichstätt Vertikal-Rollenkoffer mit integriertem Computer-Arbeitsplatz
US6241688B1 (en) * 1996-03-01 2001-06-05 Universidad Nacional Autonoma De Mexico Portable equipment for obtaining and analyzing ruminal liquid and urine
US7593222B2 (en) * 2006-01-06 2009-09-22 Raven Innovations, Inc. Laptop computer bag and backpack computer bag with extendable table and power supply
US7870937B1 (en) * 2007-03-19 2011-01-18 Albert Arnao Combination luggage and computer workstation
US8075208B2 (en) * 2007-03-28 2011-12-13 Teena Green Mobile workstation
WO2015109315A2 (fr) * 2014-01-20 2015-07-23 Brooks Automation, Inc. Poste de travail cryogénique portatif
US9820556B2 (en) * 2015-06-16 2017-11-21 Xpansion Gear, Llc System for storing, organizing, and transporting portable items
US20180193843A1 (en) * 2017-01-10 2018-07-12 Mriglobal Modular mobile field-deployable laboratory for the detection, sequencing and analysis of emerging infectious diseases

Also Published As

Publication number Publication date
GB2593098B (en) 2022-09-21
GB2606967B (en) 2023-04-19
WO2020097459A1 (fr) 2020-05-14
GB2606967A (en) 2022-11-23
EP3886650A4 (fr) 2022-10-19
GB202211403D0 (en) 2022-09-21
GB2593098A (en) 2021-09-15

Similar Documents

Publication Publication Date Title
US20220331806A1 (en) Modular mobile field-deployable laboratory for rapid, on-site detection and analysis of biological targets
US20180193843A1 (en) Modular mobile field-deployable laboratory for the detection, sequencing and analysis of emerging infectious diseases
US5788929A (en) Sample temperature protection rack
US6354104B1 (en) Lockable specimen transporter
TW201617445A (zh) 用於低功率熱循環的系統和方法
TW201723168A (zh) 用於進行化學反應的設備和方法
WO2020097459A1 (fr) Laboratoire modulaire deployable par champ mobile pour la detection et l'analyse rapides sur place de cibles biologiques
KR101415001B1 (ko) 핵산 추출 또는 증폭을 위한 휴대용 장치
CN107109334B (zh) 用于进行化学反应的设备和方法
US20080142401A1 (en) Carrying case for culinary essentials
KR20230093054A (ko) 교체 가능한 처리 모듈 및 원격 모니터링을 갖는 진단 분석 시스템
Sunagawa et al. Computational eco‐systems biology in T ara O ceans: translating data into knowledge
CN112407550A (zh) 一种医学研究用样品保存装置
Scott Environmental protection: European law and governance
Domann et al. Guidelines for reporting the use of capillary electrophoresis in proteomics
Rosebrock et al. Metabolite extraction from Saccharomyces cerevisiae for liquid chromatography–mass spectrometry
US20110220444A1 (en) Collapsible bag
CN214881515U (zh) 一种移动集成行李箱式测序平台
CN201130109Y (zh) 多功能生物样品收集保存箱式工作台
CN214608802U (zh) 便携式核酸检测箱
CN219790869U (zh) 一种血检样品密封装置
CN216735374U (zh) 一种医学化验检测用的试剂盒
CN216093770U (zh) 一种多实验样本分隔承装的生物化学实验盒
CN112320019A (zh) 便携式核酸检测箱
CN216160604U (zh) 一种便于收放的微型生态实验装置

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20210816

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
RIN1 Information on inventor provided before grant (corrected)

Inventor name: ASPINWALL, JACOB, R.

Inventor name: RUSSELL, JOSEPH, A.

Inventor name: JACOBS, JONATHAN, L.

A4 Supplementary search report drawn up and despatched

Effective date: 20220919

RIC1 Information provided on ipc code assigned before grant

Ipc: B01L 1/00 20060101ALI20220913BHEP

Ipc: A47B 37/00 20060101ALI20220913BHEP

Ipc: A47B 31/02 20060101ALI20220913BHEP

Ipc: B01L 9/02 20060101ALI20220913BHEP

Ipc: A45F 4/02 20060101ALI20220913BHEP

Ipc: A45F 3/04 20060101ALI20220913BHEP

Ipc: A45C 9/00 20060101ALI20220913BHEP

Ipc: A45C 5/14 20060101ALI20220913BHEP

Ipc: A47B 3/10 20060101ALI20220913BHEP

Ipc: A45C 5/06 20060101ALI20220913BHEP

Ipc: A45C 5/04 20060101ALI20220913BHEP

Ipc: A45C 5/03 20060101ALI20220913BHEP

Ipc: A47C 9/00 20060101AFI20220913BHEP