EP3794968A1 - Appareil de substitution du tabac - Google Patents

Appareil de substitution du tabac Download PDF

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Publication number
EP3794968A1
EP3794968A1 EP19198551.4A EP19198551A EP3794968A1 EP 3794968 A1 EP3794968 A1 EP 3794968A1 EP 19198551 A EP19198551 A EP 19198551A EP 3794968 A1 EP3794968 A1 EP 3794968A1
Authority
EP
European Patent Office
Prior art keywords
smoking substitute
vaporiser
air
substitute apparatus
vaporisation chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP19198551.4A
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German (de)
English (en)
Inventor
designation of the inventor has not yet been filed The
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nerudia Ltd
Original Assignee
Nerudia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerudia Ltd filed Critical Nerudia Ltd
Priority to EP19198551.4A priority Critical patent/EP3794968A1/fr
Priority to PCT/EP2020/076304 priority patent/WO2021053229A1/fr
Priority to EP20789852.9A priority patent/EP3930498A1/fr
Publication of EP3794968A1 publication Critical patent/EP3794968A1/fr
Priority to US17/694,919 priority patent/US20220192268A1/en
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/30—Devices using two or more structurally separated inhalable precursors, e.g. using two liquid precursors in two cartridges
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10—Devices using liquid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts

Definitions

  • Such smoking substitute systems can form part of nicotine replacement therapies aimed at people who wish to stop smoking and overcome a dependence on nicotine.
  • a vaporisable liquid, or an aerosol former sometimes typically referred to herein as “e-liquid”
  • e-liquid is heated by a heating device (sometimes referred to herein as an electronic cigarette or “e-cigarette” device) to produce an aerosol vapour which is inhaled by a user.
  • the e-liquid typically includes a base liquid, nicotine and may include a flavourant.
  • the resulting vapour therefore also typically contains nicotine and/or a flavourant.
  • the base liquid may include propylene glycol and/or vegetable glycerine.
  • the system includes a sensor for detecting when a user is inhaling through the mouthpiece, the microprocessor then activating the device in response.
  • the system When the system is activated, electrical energy is supplied from the power source to the heating device, which heats e-liquid from the tank to produce a vapour which is inhaled by a user through the mouthpiece.
  • the vaporisation chamber may have an inlet and an outlet, and the first vaporiser is located closer to the inlet than the second vaporiser.
  • the first and second vaporiser may be spaced within a plane which is transversal to a line joining the inlet and the outlet of the vaporisation chamber, such that the first airflow path extends at least through a gap between the vaporisers.
  • the gap may be aligned with the inlet of the vaporisation chamber.
  • the gap may have a width which is substantially equal to a width of the inlet to the vaporisation chamber.
  • the gap between the vaporisers may be at least 0.1 mm and no more than 5 mm.
  • the smoking substitute apparatus may comprise one or more engagement portions for engaging with a main body.
  • one end of the smoking substitute apparatus may be coupled with the main body, whilst an opposing end of the smoking substitute apparatus may define a mouthpiece of the smoking substitute system.
  • the flavourant may be provided in solid or liquid form.
  • the flavourant may be natural or synthetic.
  • the flavourant may include menthol, liquorice, chocolate, fruit flavour (including e.g. citrus, cherry etc.), vanilla, spice (e.g. ginger, cinnamon) and tobacco flavour.
  • the flavourant may be evenly dispersed or may be provided in isolated locations and/or varying concentrations.
  • the resultant aerosol particle size is advantageously controlled to be in a desirable range. It is further considered that the configuration of the apparatus can be selected so that the average magnitude of velocity of air in the vaporisation chamber can be brought within the ranges specified, at the exemplary flow rate of 1.3 L min -1 and/or the exemplary flow rate of 2.0 L min -1 .
  • the resultant aerosol particle size is advantageously controlled to be in a desirable range. It is further considered that the velocity of air in the vaporiser element region is more relevant to the resultant particle size characteristics than consideration of the velocity in the vaporisation chamber as a whole. This is in view of the significant effect of the velocity of air in the vaporiser element region on the cooling of the vapour emitted from the vaporiser element surface.
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that, when the air flow rate inhaled by the user through the apparatus is 2.0 L min -1 , the maximum magnitude of velocity of air in the vaporiser element region is in the range 0-2.0 ms -1 .
  • the air inlet, flow passage, outlet and the vaporisation chamber may be configured so that the cooling rate of the vapour is such that the time taken to cool to 50 °C is not less than 16 ms, when tested according to the following protocol.
  • the aerosol precursor is an e-liquid consisting of 1.6% freebase nicotine and the remainder a 65:35 propylene glycol and vegetable glycerine mixture, the e-liquid having a boiling point of 209 °C.
  • Air is drawn into the air inlet at a temperature of 25 °C.
  • the vaporiser is operated to release a vapour of total particulate mass 5 mg over a 3 second duration from the vaporiser element surface in an air flow rate between the air inlet and outlet of 2.0 L min -1 .
  • the e-liquid i.e. aerosol precursor
  • the tank may be refillable with e-liquid or the e-liquid may be stored in a non-consumable component of the system.
  • the e-liquid may be stored in a tank located in the main body or stored in another component that is itself not single-use (e.g. a refillable cartomizer).
  • the passage 170 may be partially defined by a tube (e.g. a metal tube) extending through the consumable 150.
  • the passage 170 is shown with a substantially circular cross-sectional profile with a constant diameter along its length.
  • the passage may have other cross-sectional profiles, such as oval shaped or polygonal shaped profiles.
  • the cross sectional profile and the diameter (or hydraulic diameter) of the passage may vary along its longitudinal axis.
  • porous wick 162 When the user inhales, air is drawn from through the inlets 176 shown in Figure 19 , along inlet flow channel 178 to vaporisation chamber inlet 172 and into the vaporisation chamber containing porous wick 162.
  • the porous wick 162 extends substantially transverse to the airflow direction.
  • the airflow passes around the porous wick, at least a portion of the airflow substantially following the surface of the porous wick 162.
  • the airflow may follow a curved path around an outer periphery of the porous wick 162.
  • Aerosol droplet size is a considered to be an important characteristic for smoking substitution devices. Droplets in the range of 2-5 ⁇ m are preferred in order to achieve improved nicotine delivery efficiency and to minimise the hazard of second-hand smoking. However, at the time of writing (September 2019), commercial EVP devices typically deliver aerosols with droplet size averaged around 0.5 ⁇ m, and to the knowledge of the inventors not a single commercially available device can deliver an aerosol with an average particle size exceeding 1 ⁇ m.
  • Table 1 shows a list of experiments in this study.
  • the values in "calculated air velocity” column were obtained by simply dividing the flow rate by the intersection area at the centre plane of wick.
  • Figures 4A-4D show air flow streamlines in the four devices used in this turbulence study.
  • Figure 4A is a standard 12mm rectangular tube with wick and coil installed as explained in the previous section, with no jetting panel.
  • Figure 4B has a jetting panel located 10mm below (upstream from) the wick.
  • Figure 4C has the same jetting panel 5mm below the wick.
  • Figure 4D has the same jetting panel 2.5mm below the wick.
  • the jetting panel has an arrangement of apertures shaped and directed in order to promote jetting from the downstream face of the panel and therefore to promote turbulent flow.
  • the jetting panel can introduce turbulence downstream, and the panel causes higher level of turbulence near the wick when it is positioned closer to the wick.
  • the four geometries gave turbulence intensities of 0.55%, 0.77%, 1.06% and 1.34%, respectively, with Figure 4A being the least turbulent, and Figure 4D being the most turbulent.
  • the CFD model outputs the average velocity and maximum velocity in the vicinity of the wick for each set of experiments carried out in section 2.1. The outcomes are reported in Table 2.
  • turbulence intensity values represent higher levels of turbulence.
  • turbulence intensity below 1% represents a low-turbulence case
  • turbulence intensity between 1% and 5% represents a medium-turbulence case
  • turbulence intensity above 5% represents a high-turbulence case.
  • Laminar mixture flow physics was selected in this study.
  • the outlet was configured in the same way as in section 3.1.
  • this model includes two fluid phases released from two separate inlets: the first one is the vapour released from wick surface, at an initial velocity of 2.84 cm/s (calculated based on 5 mg total particulate mass over 3 seconds puff duration) with initial velocity direction normal to the wick surface; the second inlet is air influx from the base of tube, the rate of which is pressure-controlled.
  • the inflow and outflow settings in heat transfer physics was configured in the same way as in the two-phase flow model.
  • the air inflow was set to 25 °C
  • the vapour inflow was set to 209 °C (boiling temperature of the e-liquid formulation).
  • the heat transfer physics is configured to be two-way coupled with the laminar mixture flow physics.
  • the above model reaches steady state after approximately 0.2 second with a step size of 0.001 second.
  • the model outputs average vapour temperature at each time steps.
  • a MATLAB script was then created to find the time step when the vapour cools to a target temperature (50°C or 75°C), based on which the vapour cooling rates were obtained (Table 3).
  • Table 3 Average vapour cooling rate obtained from Multiphysics modelling Tube size Flow rate Cooling rate to 50°C Cooling rate to 75°C [mm] [lpm] [°C/ms] [°C/ms] 1.3 Ipm constant flow rate 4.5 1.3 11.4 44.7 6 1.3 5.48 14.9 7 1.3 3.46 7.88 8 1.3 2.24 5.15 10 1.3 1.31 2.85 12 1.3 0.841 1.81 20 1.3 0* 0.536 50 1.3 0 0 2.0 lpm constant flow rate 4.5 2.0 19.9 670 5 2.0 13.3 67 6 2.0 8.83 26.8 8 2.0 3.61 8.93 12 2.0 1.45 3.19 20 2.0 0.395 0.761 50 2.0 0 0 * Zero cooling rate when the average vapour temperature is still above target temperature after
  • the graph suggests a correlation between particle size and turbulence intensity, that lower turbulence intensity is beneficial for obtaining larger particle size. It is noted that when turbulence intensity is above 1% (medium-turbulence case), there are relatively large measurement fluctuations. In Figure 13 , the tube with a jetting panel 10mm below the wick has the largest error bar, because air jets become unpredictable near the wick after traveling through a long distance.
EP19198551.4A 2019-09-20 2019-09-20 Appareil de substitution du tabac Ceased EP3794968A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP19198551.4A EP3794968A1 (fr) 2019-09-20 2019-09-20 Appareil de substitution du tabac
PCT/EP2020/076304 WO2021053229A1 (fr) 2019-09-20 2020-09-21 Appareil de substitution pour fumeurs
EP20789852.9A EP3930498A1 (fr) 2019-09-20 2020-09-21 Appareil de substitution pour fumeurs
US17/694,919 US20220192268A1 (en) 2019-09-20 2022-03-15 Smoking substitute apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19198551.4A EP3794968A1 (fr) 2019-09-20 2019-09-20 Appareil de substitution du tabac

Publications (1)

Publication Number Publication Date
EP3794968A1 true EP3794968A1 (fr) 2021-03-24

Family

ID=67998264

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19198551.4A Ceased EP3794968A1 (fr) 2019-09-20 2019-09-20 Appareil de substitution du tabac

Country Status (1)

Country Link
EP (1) EP3794968A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015079197A1 (fr) * 2013-11-26 2015-06-04 Twenty Sixteen (2016) Pharma Limited Dispositifs d'administration pulmonaire
WO2016061822A1 (fr) * 2014-10-24 2016-04-28 惠州市吉瑞科技有限公司 Ensemble d'atomisation et cigarette électronique
WO2017001818A1 (fr) * 2015-06-29 2017-01-05 Nicoventures Holdings Limited Systèmes de provision d'aérosol électronique
US20170135408A1 (en) * 2015-11-17 2017-05-18 Lunatech, Llc Electronic vapor device warning system
WO2017122196A1 (fr) * 2016-01-11 2017-07-20 Syqe Medical Ltd. Dispositif personnel de vaporisation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015079197A1 (fr) * 2013-11-26 2015-06-04 Twenty Sixteen (2016) Pharma Limited Dispositifs d'administration pulmonaire
WO2016061822A1 (fr) * 2014-10-24 2016-04-28 惠州市吉瑞科技有限公司 Ensemble d'atomisation et cigarette électronique
WO2017001818A1 (fr) * 2015-06-29 2017-01-05 Nicoventures Holdings Limited Systèmes de provision d'aérosol électronique
US20170135408A1 (en) * 2015-11-17 2017-05-18 Lunatech, Llc Electronic vapor device warning system
WO2017122196A1 (fr) * 2016-01-11 2017-07-20 Syqe Medical Ltd. Dispositif personnel de vaporisation

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