EP3794962A1 - Article sans fumée - Google Patents

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Publication number
EP3794962A1
EP3794962A1 EP19198288.3A EP19198288A EP3794962A1 EP 3794962 A1 EP3794962 A1 EP 3794962A1 EP 19198288 A EP19198288 A EP 19198288A EP 3794962 A1 EP3794962 A1 EP 3794962A1
Authority
EP
European Patent Office
Prior art keywords
coating
porous substrate
pouch
smokeless
porous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP19198288.3A
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German (de)
English (en)
Inventor
designation of the inventor has not yet been filed The
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nerudia Ltd
Original Assignee
Nerudia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nerudia Ltd filed Critical Nerudia Ltd
Priority to EP19198288.3A priority Critical patent/EP3794962A1/fr
Priority to EP20788984.1A priority patent/EP4030935A1/fr
Priority to PCT/EP2020/075907 priority patent/WO2021053036A1/fr
Publication of EP3794962A1 publication Critical patent/EP3794962A1/fr
Priority to US17/697,326 priority patent/US20220202071A1/en
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F23/00—Cases for tobacco, snuff, or chewing tobacco
    • A24F23/02—Tobacco pouches
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B13/00—Tobacco for pipes, for cigars, e.g. cigar inserts, or for cigarettes; Chewing tobacco; Snuff
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/186—Treatment of tobacco products or tobacco substitutes by coating with a coating composition, encapsulation of tobacco particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D1/00—Processes for applying liquids or other fluent materials
    • B05D1/02—Processes for applying liquids or other fluent materials performed by spraying

Definitions

  • the present invention relates to a smokeless article for oral consumption, and a method of manufacturing a smokeless article for oral consumption.
  • Smoking is generally considered to expose a smoker to potentially harmful substances. It is generally thought that the majority of the potentially harmful substances are formed by the heat generated during burning (combustion) of the article. There is interest in so-called heat not burn products, which heat a tobacco or similar substrate at a lower temperature than a conventional cigarette. These products are usually described as less harmful than conventional cigarettes. Both conventional cigarettes and heat not burn products are visible during use and produce smoke or vapour.
  • Smokeless articles are a suitable alternative because they do not require heating for substance delivery to the user. Instead, smokeless articles rely on saliva to extract soluble substances, typically nicotine and/or flavours, from tobacco contained within the smokeless article.
  • Conventional smokeless articles have a saliva permeable pouch housing a content.
  • the content is generally in the form of tobacco.
  • Such a product may be referred to as portion snus. It is typically provided as prepackaged (traditionally moist) powder in small teabag-like pouches. Each pouch is a single portion or unit. This moistened product may be referred to as original snus.
  • Smokeless articles are placed in the mouth where saliva extracts the soluble element from the tobacco contained within.
  • the smokeless article is placed in the oral cavity, sublingually or in the oral vestibule (between the teeth and lips/cheeks).
  • the user may assist extraction by oral manipulation, such as by chewing and/or sucking or pressing on the outside of the mouth to squeeze the pouch.
  • the resulting saliva which contains extracts, subsequently contacts a mucous membrane in the mouth, or at another point of the gastrointestinal tract, to deliver the soluble element across the membrane and into the bloodstream.
  • the soluble element is then transported by the bloodstream to the site of action. For example, nicotine is delivered to the brain where it acts upon acetylcholine receptors.
  • Snuff is smokeless tobacco made from ground or pulverised tobacco leaves. Snuff is available in dry form or wet (moist) form. Moist snuff may be referred to as snus. Two common varieties of snus are Scandinavian snus and American snus. Both varieties of snus are available in a loose form, but are often contained within a saliva permeable pouch.
  • snus is typically manufactured by grinding a blend of leaf tobaccos to specified particle sizes.
  • the ground tobacco is then mixed with water and sodium chloride in closed process blenders.
  • the mixture is subjected to a heat treatment, involving temperatures up to 80 - 100 °C, for several hours to pasteurize the snus. Thereafter, the snus is cooled and other ingredients may be added.
  • Snus is typically manufactured to meet the GothiaTek® standard, as detailed in " Swedish snus and the GothiaTek® standard” (2005), Rutqvist , et al.
  • content(s) is intended to refer to compounds, material and/or substances that may be enclosed within the pouch.
  • nicotine is intended to refer to nicotine, nicotine salt(s), nicotine complex(es); and/or nicotine solvate(s).
  • non-porous is intended to refer to a material that does not include any pores extending through the thickness of the wall (for instance, “through holes” or capillaries).
  • saliva-stable is intended to refer to a material that does not substantially dissolve or disintegrate as a result of exposure to saliva in the oral cavity of the user at physiological temperature. Therefore a layer of such material is resistant to the migration of saliva (or compounds/substances dissolvable in saliva, for example nicotinic compounds) through the thickness of the material.
  • the material may also be resistant to migration of saliva (or compounds/substances dissolvable in saliva e.g. nicotinic compounds) by phase transfer mechanisms. In some cases a standard commercially available artificial saliva may be used to test saliva-stability.
  • “saliva-stable” may equate to “water-stable” and refer to a material that does not substantially dissolve or disintegrate as a result of exposure to water in the oral cavity of the user at physiological pH.
  • a layer of the material is resistant to the migration of water (or compounds/substances dissolvable in water, for example nicotinic compounds) through the thickness of the material.
  • the material may also be resistant to migration of water (or compounds/substances dissolvable in water e.g. nicotinic compounds) by phase transfer mechanisms.
  • saliva is intended to refer to the liquid substance formed in the mouth of animals, such as humans, that includes water, electrolytes and enzymes. Other components of saliva may include mucus, white blood cells, epithelial cells and/or antimicrobial agents.
  • hydrophobic is intended to refer to a material having water contact angle greater than 90°, such that the material is resistant to adsorption and/or absorption of water. In some instances such material may have a polarity lower than that of water.
  • plant material is intended to refer to a portion and/or part(s) of a plant (e.g. leaf, stem, flower or bud).
  • the plant material may be processed (for example, by shredding, grinding or drying) or it may be non-processed (that is, used whole).
  • the plant material is typically fibrous (comprising or characterised by fibres).
  • plant material is not intended to include pulp and/or paper which is derived from a plant material (typically wood) and chemically and/or mechanically processed to extract fibres before use.
  • moisture content may include water, humectants, liquid flavourants and/or other liquid compounds.
  • oral consumption is intended to refer to any oral administration route achieved by placing the smokeless article into the oral cavity. This includes, but is not limited to, buccal, sublingual, periodontal, gingival and ingestion.
  • a smokeless article for oral consumption comprising a pouch, the pouch comprising a porous substrate enclosing a content, the content comprising a nicotinic compound, wherein the porous substrate has a continuous coating of a non-porous, saliva-stable material, and wherein the coating is frangible, such that in use the coating fractures on chewing.
  • the coating of a non-porous, saliva-stable material prohibits migration of saliva (or water) into the content of the pouch.
  • the non-porous, saliva-stable material also acts to prohibit migration of the nicotinic compound from the content of the pouch into the user's oral cavity. Therefore, release of the nicotinic compound from the pouch into the user's oral cavity is prevented.
  • the frangible nature of the coating enables the user to bite down or chew on the pouch to break the coating. This exposes a portion of porous substrate that was previously covered by the coating, and facilitates migration of saliva (or water) from the user's oral cavity into the content of the pouch.
  • the saliva extracts soluble components contained within the content (in particular, the nicotinic compound), and delivers the extracted components from the pouch into the user's oral cavity.
  • the user has complete control over when the release of the nicotinic compound is initiated. For instance, when a nicotine "hit" is desired by the user, they can simply bite down on the pouch to break the frangible coating and initiate release of the nicotinic compound.
  • the presence of the continuous coating of non-porous, saliva-stable material imparts an additional benefit that the loss of moisture from the content of the pouch prior to use is retarded.
  • the coating retards or prevents the passage of moisture with the result that the rate of loss of moisture from the content over time is reduced as compared to a smokeless article having no such coating or in which the coating is breached; providing a smokeless article having a longer shelf-life.
  • the coating is located on an inner surface of the porous substrate; in some cases exclusively on the inner surface of the porous substrate.
  • the coating is shielded from premature breakage as it is contained on a surface that is within the enclosed volume of the pouch.
  • the coating is located on an outer surface of the porous substrate; in some cases exclusively on the outer surface of the porous substrate.
  • the coating may provide an improved mouth-feel to the user because, in use, the coating is in direct contact with the user's oral cavity.
  • the coating may provide a surface that feels smoother against the user's oral cavity e.g. as compared to the porous substrate.
  • inner surface is intended to refer to the surface of the porous substrate that is closest to the content contained within the pouch.
  • outer surface is intended to refer to the surface of the porous substrate furthest away from the content contained within the pouch.
  • the non-porous, saliva-stable material comprises a polymer.
  • the physical properties of the non-porous, saliva-stable material can easily be tuned by selection of an appropriate polymer. This is advantageous from a manufacturing and processability perspective. It is also advantageous from the perspective of use of the article. For example, the degree of frangibility of the coating can be tuned be selection of an appropriate polymer.
  • the polymer is selected from sorbitol, maltitol, isomalt, mannitol, starch, gelatin, gum arabic, polyvinyl acetate, carob bean gum, refined paraffin wax, shellac, locust bean gum, petroleum wax, terpene resin, tragacanth, polyethylene, xanthan gum, and combinations thereof.
  • essentially the entire enclosed volume of the pouch is defined by the porous substrate.
  • the non-porous, saliva-stable material is hydrophobic.
  • the coating more effectively repels saliva (or water) to prevent the migration of saliva (or water) through the porous substrate.
  • the content is tobacco-free.
  • the user may experience a similar or enhanced recreational/pharmaceutical effect as compared to conventional tobacco-containing products without experiencing undesirable components inherent to tobacco (e.g. tobacco flavour).
  • tobacco flavour undesirable components inherent to tobacco
  • the coating may be applied to the porous substrate by any suitable means, for example, brushing, spraying, or immersion. It is preferred that the coating is uniform across a surface of the porous substrate.
  • the coating is applied by spray coating.
  • a smokeless article for oral consumption comprising:
  • the coating material may be applied to the sheet of a porous substrate on a surface intended to be the inner surface of the porous substrate when it is made into a pouch.
  • the coating material may be applied to the sheet of a porous substrate on a surface intended to be the outer surface of the porous substrate when it is made into a pouch.
  • the coating material may be applied to both of said surfaces.
  • the coating material is typically applied to the porous substrate sheet in a spreadable or sprayable state, for example as a liquid or paste. After application, the coating material then becomes frangible over time, for example upon curing or evaporation of solvent. In some cases the coated sheet of porous substrate is formed into a pouch before the coating material becomes frangible, this reduces the incidence of cracking or other breaching of the coating upon formation of the pouch. This may involve formation of a pouch that is still open along at least a portion of at least one side to allow contents to be filled into the pouch, or it may involve complete formation and filling of the closed pouch before the coating material becomes frangible. As such the method may further include a step of curing or allowing solvent to evaporate from the coating material to form a frangible coating. This step may occur between steps (i) and (ii) above; or between steps (ii) and (iii) above; or following step (iii) above.
  • step (ii) the coated sheet of porous substrate is arranged such that the coating of the non-porous, saliva-stable material is provided on an inner surface of the porous substrate.
  • the coating material is applied by spray-coating.
  • a smokeless article for oral consumption produced by a process according to the second aspect.
  • kits comprising a plurality of smokeless articles according to the first aspect and/or the third aspect and a container.
  • the smokeless article may be described as a snus article.
  • the smokeless article preferably has a mass of about 0.1 g to 5.0 g, such as about 0.5 g to about 4.0 g or about 1.0 g to about 3.0 g.
  • the smokeless article preferably has a length of about 30 mm, such as about 28 mm or 26 mm, a width of about 12 mm, such as about 10 mm or 8 mm, and a depth of about 5 mm, such as about 4 mm or 3 mm.
  • the porous substrate may be comprised of one or more materials.
  • the porous substrate may be comprised of fiber, paper, cloth and fabric or combinations thereof.
  • the porous substrate may be comprised of one or more polymeric materials.
  • the polymeric material may be selected from one or more of hydroxypropyl cellulose (HPC), hydroxypropyl methylcellulose (HPMC), polyvinyl alcohol (PVOH), polyvinylpyrrolidone (PVP), polyethylene oxide (PEO) hydroxyethyl cellulose (HEC), polyethylene glycol (PEG), pullulan, sodium alginate, xanthan gum, tragancanth gum, guar gum, acacia gum, arabic gum, polyacrylic acid, maltodextrin, methylmethacrylate copolymer, carboxyvinyl copolymers, starch and gelatin.
  • the porous substrate is typically completely insoluble in saliva.
  • Suitable insoluble porous substrate materials include, but are not limited to, fiber, paper, water-insoluble polymers, cloth and fabric.
  • Suitable soluble porous substrate materials include, but are not limited to, water-soluble polymers such as polyethylene oxide (PEO), hydroxypropyl cellulose (HPC) and hydroxypropyl methylcellulose (HPMC).
  • the pouch may be formed by, for example, folding a single sheet of porous substrate on itself or bringing two or more sheets of a porous substrate together and sealing the edges.
  • the edges may initially be partially sealed to provide an open pouch in which the content may be placed before completely sealing the pouch closed.
  • the sheets may be the same thickness or different thicknesses.
  • At least 50% of the pores of the porous substrate have a diameter of 50 ⁇ m to 200 ⁇ m, such as 100 ⁇ m to 175 ⁇ m or 125 ⁇ m or 150 ⁇ m. At least 50% of the pores have a diameter of at least 100 ⁇ m. For example, at least 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95% or 100% of the pores have such diameters.
  • the pouch may be coloured or include markings, such as brand logos and text, to improve user perception.
  • the pouch may be partially or completely coloured by a colourant.
  • the content may comprise one or more substances.
  • the or each substance may individually be a biologically/pharmacologically active compound, pH stabilisers or adjusters, humectants, flavourants, fillers, preservatives, aqueous/non-aqueous solvents and binders.
  • the or each substance may be provided for more than one purpose.
  • the content of the pouch preferably occupies substantially all of the internal volume of the pouch.
  • the content may occupy 80%, 85%, 90%, 95% or 100% of the internal volume of the pouch.
  • the content may comprise a solid material to provide physical integrity, such as an organic material (e.g. plant material) or an inorganic material. Such solid materials may naturally or inherently contain one or more biologically/pharmacologically active compounds and/or additives.
  • Biologically/pharmacologically active compounds are provided to produce a pharmacological effect in the user.
  • Suitable biologically/pharmacologically active compounds include the group consisting of: nicotine, cocaine, caffeine, opiates and opioids, cathine and cathinone, kavalactones, mysticin, beta-carboline alkaloids, salvinorin A together with any combinations, functional equivalents to, and/or synthetic alternatives of the foregoing.
  • Biologically/pharmacologically active compounds may also have additive properties.
  • the content may include a nicotine salt.
  • the content may include a nicotine salt selected from the group consisting of nicotine hydrochloride, nicotine dihydrochloride, nicotine monotartrate, nicotine bitartrate, nicotine bitartrate dehydrate, nicotine sulfate, nicotine zinc chloride monohydrate, nicotine salicylate and mixtures thereof.
  • pH stabilisers or adjusters may be provided to adjust the user experience and/or modify the bioavailability of a pharmacologically active compound. For instance, under acidic conditions, nicotine is protonated and does not readily cross mucous membranes.
  • suitable pH stabilisers include ammonia, ammonium carbonate, sodium carbonate and calcium carbonate.
  • the overall pH of the smokeless article is preferably pH 7 to pH 9, such as pH 7.25 to pH 8.75 or pH 7.5 to pH 8.5.
  • the overall pH of a smokeless article may be determined by, for example, (i) placing the content of the smokeless article in 10 mL of distilled water (iii) agitating the mixture for at least 5 minutes and (iv) measuring the pH of the solution with a pH probe.
  • Fillers may be provided to increase the volume of the smokeless article (e.g. by increasing the volume contained within the pouch and to strengthen the content).
  • Suitable fillers include calcium carbonate, calcium phosphate, corn starch, grains, lactose, polysaccharides (e.g. maltodextrin), polyols, sugars (e.g. dextrose, manitol, xylitol, sorbitol), natural fibres (e.g. non-tobacco fibres), microcrystalline cellulose, cellulose and cellulose derivatives (e.g. finely divided cellulose), lignocellulose fibres (e.g. wood fibres), jute fibres and combinations thereof.
  • the amount of filler is 5 to 10 wt% of the content e.g. around 6 to 9 wt%.
  • Flavourants may be provided in solid or liquid form. Suitable flavourants include coffee, eucalyptus, menthol, liquorice, peppermint, spearmint, chocolate, fruit flavour (including e.g. citrus, cherry etc.), vanilla, spice (e.g. ginger, cinnamon) and tobacco flavour.
  • the flavourant may be evenly dispersed throughout the content or may be provided in isolated locations and/or varying concentrations throughout the content.
  • the term "flavourant” denotes a compound having a desirable taste, aroma or both.
  • Humectants may be provided to control moisture content thereby preventing the smokeless article from drying out during storage and reducing the amount of saliva wetting required before the user experience begins.
  • Suitable humectants include polyhydric alcohols (e.g. propylene glycol (PG), triethylene glycol, 1,2-butane diol and vegetable glycerine (VG)) and their esters (e.g. glycerol mono-, di- or tri-acetate).
  • the humectant may have a lower limit of at least 1 % by weight of the content such as at least 2 wt%, such as at least 5 wt%, such as at least 10 wt%, such as at least 20 wt%, such as at least 30 wt%, or such as least 40 wt%.
  • the humectant may have an upper limit of at most 50% by weight of the contents, such as at most 40 wt%, such as at most 30 wt%, or such as at most 20 wt%, such as at most 10 wt %, such as at most 5 wt %, such as at most 2 wt%.
  • the amount of humectant is 1 to 40 wt% of the content, such as 2 to 20 wt% or 5 to 10 wt%.
  • Smokeless articles having a total moisture content of 10% or less are generally considered to be 'dry'.
  • Smokeless articles having a total moisture content of 40% or more are generally considered to be 'wet'.
  • Sweeteners may be provided to modify the user taste perception and, in particular, overcome bitter flavours that result from other substances.
  • Suitable sweeteners include honey, sugar, brown sugar, glucose, fructose, sucrose, aspartame, xylitol, maltitol, saccharin sodium, glycyrrhizin tripotassium liquorice, jujube or a mixture thereof.
  • the amount of sweetener is in some cases 1 to 20 % by weight of the content, such as 2 to 15 wt% or 5 to 10 wt%.
  • Stabilisers are provided to prevent decomposition or degradation over time during storage by, for example, retarding oxidation or unwanted biological activity.
  • Stabilisers may be selected from the group consisting of antioxidants including vitamin E, such as tocopherole, ascorbic acid, sodium pyrosulfite, butylhydroxytoluene, butylated hydroxyanisole, edetic acid and salts thereof; and preservatives including citric acid, tartaric acid, lactic acid, malic acid, acetic acid, benzoic acid, sorbic acid and salts thereof.
  • vitamin E such as tocopherole, ascorbic acid, sodium pyrosulfite, butylhydroxytoluene, butylated hydroxyanisole, edetic acid and salts thereof
  • preservatives including citric acid, tartaric acid, lactic acid, malic acid, acetic acid, benzoic acid, sorbic acid and salts thereof.
  • Binders may be provided. Suitable binders include starches and/or cellulosic binders such as methyl cellulose, ethyl cellulose, hydroxypropyl cellulose, hydroxyethyl cellulose and carboxymethyl cellulose, gums such as xanthan, guar, arabic and/or locust bean gum, organic acids and their salts such as alginic acid (sodium alginate), agar and pectins. In some embodiments the amount of binder is 5 to 10 wt% of the content e.g. around 6 to 9 wt% or 7 to 8 wt%.
  • Colourants may be provided to modify the user impression of the smokeless article. Colourants include whitening agents. Colourants may be selected from one or more of common colourants such as curcumin (E100), turmeric (E100(ii)), riboflavin (E101), riboflavin-5'-phosphate (E101(ii)), tartrazine (E102), quinoline yellow (E104), riboflavin-5-sodium phosphate (E106), yellow 2G (E107), sunset yellow FCF (E110), carmine, cochineal (E120), azorubine (E122), amaranth (E123), ponceau 4R (E124), erythrosine (E127), red 2G (E128), allura red AC (E129), patent blue V (E131), indigotine (E132), brilliant blue FCF (E133), chlorophylls (E140), copper complexes of chlorophyll (E141), green S (E142), caramel (E150a-d), brilliant black BN (E
  • Plant material may be provided for physical integrity and may function as a natural source of substances such as, for example, biologically/pharmacologically active compounds, flavourants, pH stabilisers etc.
  • the plant material may comprise least one plant material selected from the list including Amaranthus dubius, Arctostaphylos uva-ursi (Bearberry), Argemone mexicana, Amica, Artemisia vulgaris, Yellow Tees, Galea zacatechichi, Canavalia maritima (Baybean), Cecropia mexicana (Guamura), Cestrum noctumum, Cynoglossum virginianum (wild comfrey), Cytisus scoparius, Damiana, Entada rheedii, Eschscholzia califomica (California Poppy), Fittonia albivenis, Hippobroma longiflora, Humulus japonica (Japanese Hops), Humulus lup
  • the plant material may be tobacco. Any type of tobacco may be used. This includes, but is not limited to, flue-cured tobacco, burley tobacco, Maryland Tobacco, dark-air cured tobacco, oriental tobacco, dark-fired tobacco, perique tobacco and rustica tobacco. This also includes blends of the above mentioned tobaccos.
  • any suitable parts of the tobacco plant may be used. This includes leaves, stems, roots, bark, seeds and flowers.
  • the tobacco may comprise one or more of leaf tobacco, stem tobacco, tobacco powder, tobacco dust, tobacco derivatives, expanded tobacco, homogenised tobacco, shredded tobacco, extruded tobacco, cut rag tobacco and/or reconstituted tobacco (e.g. slurry recon or paper recon).
  • the content may comprise at least 50 wt% plant material based on the weight of the content, e.g. at least 60 wt% plant material e.g. around 65 wt% plant material.
  • the content may comprise 80 wt% or less plant material e.g. 75 or 70 wt% or less plant material.
  • the content may comprise a gathered sheet of homogenised (e.g. paper/slurry recon) tobacco or gathered shreds/strips formed from such a sheet.
  • homogenised e.g. paper/slurry recon
  • the sheet may have a grammage greater than or equal to 100 g/m 2 , e.g. greater than or equal to 110 g/m 2 such as greater than or equal to 120 g/m 2 .
  • the sheet may have a grammage of less than or equal to 300 g/m 2 e.g. less than or equal to 250 g/m 2 or less than or equal to 200 g/m 2 .
  • the sheet may have a grammage of between 120 and 190 g/m 2 .
  • a smokeless article 10 having a pouch 12, the pouch being a porous substrate having an inner surface 17 and an outer surface 18.
  • the pouch 12 contains a content 14 including a nicotinic compound.
  • the pouch 12 is substantially rectangular.
  • the pouch 12 is formed from a single sheet of a porous substrate and is substantially filled by the content 14.
  • the pouch 12 has a seal 16 along each of the three edges where the inner surface 17 of the single sheet of porous substrate meets itself to seal the contents 14 in the pouch 12.
  • the inner surface 17 of the porous substrate has a continuous coating 19 of a non-porous, saliva-stable material between the content 14 and the pouch 12. The coating 19 being frangible.
  • the smokeless article 10 is placed into the oral cavity of the user. Due to the coating 19, saliva present in the user's oral cavity is prohibited from contacting the content 14 contained within the pouch. Nor can the nicotinic compound in the content 14 migrate through the coating 19.
  • saliva When the user desires a nicotine "hit” they bite down or chew on the smokeless article to break the coating 19. This exposes a portion of the porous substrate of the pouch, such that saliva can migrate through the porous substrate and contact the content 14 contained within. A nicotinic compound within the content 14 is then extracted into the saliva and may enter the user's blood stream by oral consumption to provide a nicotine "hit".
  • FIG 2 shows a second embodiment of a smokeless article 10' having a pouch 12, the pouch being a porous substrate having an inner surface 17 and an outer surface 18.
  • the pouch 12 contains a content 14 including a nicotinic compound.
  • the pouch 12 is substantially circular.
  • the pouch 12 is formed from two opposing sheets of a porous substrate and is substantially filled by the content 14.
  • the pouch 12 has a circumferential seal 16 along the edges where the two opposing sheets of a porous substrate meet to seal the contents 14 in the pouch 12.
  • the outer surface 18 of the porous substrate has a continuous coating 19 of a non-porous, saliva-stable material surrounding the pouch 12. The coating 19 being frangible.
  • Figure 3 shows a third embodiment of a smokeless article 10" that, like the first embodiment, has a pouch 12 made from a single sheet of a porous substrate.
  • one of the three seals 16' is formed by an overlap of the inner surface 17 and the outer surface 18 of the single sheet of porous substrate to seal the contents 14 in the pouch 12.
  • the remaining two seals at opposing ends of the pouch are formed where the inner surface 17 of the single sheet of porous substrate meets itself.
  • the inner surface 17 of the porous substrate has a continuous coating 19 of a non-porous, saliva-stable material between the content 14 and the pouch 12.
  • the coating 19 being frangible.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
EP19198288.3A 2019-09-19 2019-09-19 Article sans fumée Ceased EP3794962A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP19198288.3A EP3794962A1 (fr) 2019-09-19 2019-09-19 Article sans fumée
EP20788984.1A EP4030935A1 (fr) 2019-09-19 2020-09-16 Article sans fumée
PCT/EP2020/075907 WO2021053036A1 (fr) 2019-09-19 2020-09-16 Article sans fumée
US17/697,326 US20220202071A1 (en) 2019-09-19 2022-03-17 Smokeless article

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EP19198288.3A EP3794962A1 (fr) 2019-09-19 2019-09-19 Article sans fumée

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EP3794962A1 true EP3794962A1 (fr) 2021-03-24

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11206872B2 (en) 2020-04-07 2021-12-28 Consumernext Labs Gmbh Stable-foam dispensing device and cartridge
WO2023143687A1 (fr) * 2022-01-28 2023-08-03 Mac Baren Tobacco Company A/S Composition en sachet ayant un rapport nicotine/solvant spécifique

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11872231B2 (en) 2019-12-09 2024-01-16 Nicoventures Trading Limited Moist oral product comprising an active ingredient
US11969502B2 (en) 2019-12-09 2024-04-30 Nicoventures Trading Limited Oral products
EP4272582B1 (fr) * 2022-05-05 2024-10-09 Swedish Match North Europe AB Produit en sachet à usage oral comprenant des particules de substrat insolubles dans l'eau

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WO2007084587A2 (fr) * 2006-01-20 2007-07-26 Monosol Rx, Llc Emballages doublés d'un film et leur procédé de fabrication
WO2009010875A2 (fr) * 2007-07-16 2009-01-22 Philip Morris Products S.A. Produit en sachet pour administration orale à joint revêtu
WO2013192519A1 (fr) * 2012-06-22 2013-12-27 R. J. Reynolds Tobacco Company Matériaux composites contenant du tabac

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Publication number Priority date Publication date Assignee Title
EP3614869A1 (fr) * 2017-04-24 2020-03-04 Swedish Match North Europe AB Produit humide et aromatisé à base de nicotine sous forme de sachet pour administration orale comprenant un triglycéride

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WO2007084587A2 (fr) * 2006-01-20 2007-07-26 Monosol Rx, Llc Emballages doublés d'un film et leur procédé de fabrication
WO2009010875A2 (fr) * 2007-07-16 2009-01-22 Philip Morris Products S.A. Produit en sachet pour administration orale à joint revêtu
WO2013192519A1 (fr) * 2012-06-22 2013-12-27 R. J. Reynolds Tobacco Company Matériaux composites contenant du tabac

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Title
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11206872B2 (en) 2020-04-07 2021-12-28 Consumernext Labs Gmbh Stable-foam dispensing device and cartridge
WO2023143687A1 (fr) * 2022-01-28 2023-08-03 Mac Baren Tobacco Company A/S Composition en sachet ayant un rapport nicotine/solvant spécifique

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EP4030935A1 (fr) 2022-07-27
US20220202071A1 (en) 2022-06-30
WO2021053036A1 (fr) 2021-03-25

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