EP3782163A1 - Procédé et dispositif de commande d'un dispositif d'analyseur pour effectuer une analyse d'un échantillon de matière - Google Patents

Procédé et dispositif de commande d'un dispositif d'analyseur pour effectuer une analyse d'un échantillon de matière

Info

Publication number
EP3782163A1
EP3782163A1 EP19719241.2A EP19719241A EP3782163A1 EP 3782163 A1 EP3782163 A1 EP 3782163A1 EP 19719241 A EP19719241 A EP 19719241A EP 3782163 A1 EP3782163 A1 EP 3782163A1
Authority
EP
European Patent Office
Prior art keywords
analysis
sample material
analyzer
commands
parameter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19719241.2A
Other languages
German (de)
English (en)
Inventor
Jochen Rupp
Tom Doehring
Karsten Seidl
Tino Frank
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Robert Bosch GmbH
Original Assignee
Robert Bosch GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robert Bosch GmbH filed Critical Robert Bosch GmbH
Publication of EP3782163A1 publication Critical patent/EP3782163A1/fr
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices

Definitions

  • the invention is based on a device or a method according to the preamble of the independent claims.
  • the subject of the present invention is also a computer program.
  • IVD In vitro diagnostics
  • Lab-on-chip devices are usually based on a measuring method (eg PCR,
  • Fluorescence measurement, pH measurement develop or optimized.
  • Control system as universal as possible, so that no reimplementation for new applications is necessary. It should be possible to fall back on an arsenal of existing commands and structures and only supplement missing structures and commands to the existing one.
  • Execution unit of the analyzer from a command library (for the execution unit);
  • an analyzer can be understood to mean a device for medical or biochemical analysis of samples.
  • Sample material can be understood, for example, as a piece of human or animal tissue or a corresponding body fluid.
  • a usage parameter may be understood as information that is manually or automatically supplied to the analyzer and that specifies which type or type of analysis is to be applied to the sample material.
  • a control command can be understood to mean a machine-interpretable information or a control command, which action or action should execute an execution unit as part of the analysis device or as a unit coupled to the analyzer. Such action or action may be, for example, processing of the sample material or detection of a parameter of the sample material.
  • Command library can be understood, for example, a command memory as a sub-element of the analyzer. Alternatively or additionally, the
  • Command library also be arranged entirely or at least partially external to the analyzer, for example as part of a cloud computer network or on a memory of a container containing the sample material.
  • the approach presented here is based on the knowledge that an analysis of the sample material to be performed requires a wide variety of actions or actions.
  • different sample material depending on the analysis to be performed, treated in various ways or censored thereof a parameter, usually one or more execution units can be used as actuators that can make a variety of actions or actions with the sample material.
  • the selection of a plurality of drive commands from a command library thus makes it possible to carry out a very flexible adaptation or flexible use of the execution unit for a wide variety of analyzes to be carried out.
  • the execution unit can now be actuated with an individual number or sequence of activation commands in order to carry out the currently performed analysis of the sample material.
  • the approach presented here thus offers the advantage, depending on the current desired analysis of the sample material to be carried out, of being able to carry out an individual compilation of activation commands for the execution unit of the analysis device from the command library.
  • the analyzer or the execution unit can be in a very use flexible manner, whereby the usability and thus the operational value of the analyzer or the execution unit can be increased accordingly.
  • Control commands for processing options of the sample material depending on the currently required or to be performed analysis, to be able to put together individually to the instruction set. In this way, depending on the requirements of a temporal sequence of processing step of the sample material for different analyzes to be performed, the execution unit with
  • control corresponding control commands so that a very high flexibility in the use of the execution unit can be achieved.
  • Another advantage is an embodiment of the approach proposed here, in which the control commands for a plurality of execution units are loaded in the step of loading, wherein in the step of driving the plurality
  • Execution units are driven using the control commands to analyze the sample material.
  • Such an embodiment of the approach proposed here has the advantage that, for example, individual execution units do not necessarily have to be configured in such a way that they must be able to perform all the actions corresponding to the respective activation commands. Rather, the required according to the current analysis of the sample material required actions or steps in different execution units can be executed or controlled, which can be technically simpler configured and thus use less expensive execution units or modular analyzers for cost-effective analysis of the sample material.
  • a step of storing an analysis result of an analysis of the sample material may be provided, wherein the analysis result is linked to data or metadata which includes an origin of the sample material, an analysis parameter and / or an information on a permission of a display or a dissemination of the analysis result.
  • An origin of the sample material may, for example, be understood as a name or an indication of the supplier of the sample material.
  • an analysis parameter may be understood, for example, a physiological, biological or chemical parameter that was measured in the analysis of the sample material.
  • Information about the authorization of an advertisement or a dissemination of the analysis result may, for example, be information which indicates that the output or
  • Dissemination of the analysis result can be suppressed and / or released only for a particular interrogator.
  • Such an embodiment of the approach proposed here offers the advantage of being able to release a transmission or an output of the analysis result very accurately, so that such information can already be combined or stored together with the analysis result itself and thus reduces or at best lowers the analysis result Case can be completely prevented.
  • Command library unknown control command for controlling the at least one execution unit is provided.
  • Such an embodiment of the approach proposed here offers the advantage that in the production of the execution unit possible, but not yet specifically specified
  • Control command can be stored in the command library. In this way you can have the flexibility to use one already
  • Execution unit or the analysis unit were not yet known.
  • Another advantage is an embodiment of the approach proposed here, in which at least one heating, moving, illuminating, exposing, sonicating and / or sensing a parameter of the at least one drive command in the execution unit in the step of driving
  • Sample material is performed.
  • a physiological, biological or chemical parameter such as a viscosity of blood, the presence of an antigen after vaccination or the like
  • a check is carried out as to whether an analysis of the sample material to be carried out by the user parameter can or should be carried out in the analyzer.
  • no control commands can be loaded from the command library if the analysis of the sample material to be carried out by the user parameter in the
  • a user parameter may, for example, be understood to be a parameter which provides information on which user, for example a patient, a doctor or a public authority representative, is currently using the analyzer or in which environmental scenario, for example in a clinic, a doctor's practice or privately by a user at home, the analyzer is currently in progress or the analysis to be performed is to be performed.
  • the analyzer is currently in progress or the analysis to be performed is to be performed.
  • the execution unit may be designed such that a control command is only executed when the sample material or the analysis process has reached a specific parameter or a specific criterion, for example has a predetermined temperature.
  • in the step of driving the execution unit can be controlled taking into account an intervention parameter by means of the control commands, in particular wherein the intervention parameter is read using a man-machine interface and / or using an automatically read intervention parameter.
  • an intervention parameter is read using a man-machine interface and / or using an automatically read intervention parameter.
  • An automatically read intervention parameter which is read, for example, from a container containing the sample material, offers the advantage that for certain analyzes to be carried out the flow control of the
  • a step of connecting the analyzer is provided with a central computer unit, wherein the computer unit is arranged externally to the analyzer and wherein in the step of connecting at least one drive command is loaded from the central computer unit and / or a Analysis result of the sample material is stored on a central computer unit.
  • the analysis result can also be assessed by one or more external experts without them having to come close to the analyzer or the corresponding execution unit.
  • At least one drive command can be loaded from a memory which is arranged outside the analyzer. This way, one for one
  • Control commands or the selection of control commands for a particularly efficient execution of the analysis on at least one execution unit are made.
  • This method can be implemented, for example, in software or hardware or in a mixed form of software and hardware, for example in a control unit.
  • the approach presented here also provides a device which is designed to implement the steps of a variant of a method presented here
  • the device may comprise at least one computing unit for processing signals or data, at least one memory unit for storing signals or data, at least one interface to a sensor or an actuator for reading sensor signals from the sensor or for outputting data or control signals to the sensor Actuator and / or at least one
  • the arithmetic unit may be, for example, a signal processor, a microcontroller or the like, wherein the memory unit may be a flash memory, an EEPROM or a magnetic memory unit.
  • the communication interface may be configured to read in or output data wirelessly and / or by line, wherein a communication interface that can input or output line-connected data can, for example, electrically or optically send this data from a corresponding data transmission line or output to a corresponding data transmission line.
  • a device can be understood as meaning an electrical device which processes sensor signals and outputs control and / or data signals in dependence thereon.
  • the device may have an interface, which may be formed in hardware and / or software.
  • the interfaces can be part of a so-called system ASIC, for example, which contains a wide variety of functions of the device.
  • the interfaces are their own integrated circuits or at least partially consist of discrete components.
  • the interfaces may be software modules that are present, for example, on a microcontroller in addition to other software modules.
  • a computer program product or computer program with program code which can be stored on a machine-readable carrier or storage medium such as a semiconductor memory, a hard disk memory or an optical memory and for carrying out, implementing and / or controlling the steps of the method according to one of the above
  • Fig. 1 shows a block diagram of an embodiment of a
  • Figure 2 is a schematic representation of the structure and operation of the loading unit with a protocol library.
  • Fig. 3 is a schematic representation of a general construction of the
  • FIG. 4 shows a block diagram of an extended, universal system of a further embodiment of an analysis device
  • Fig. 5 is a schematic block diagram representation of another
  • FIG. 6 is a flowchart of a method according to a
  • execution units 110a to 11Od are designed, for example, to produce a sample material 115 which, for example, is covered by a human or animal tissue
  • Body fluid or the like is formed to receive and process in accordance with a predetermined processing rule in order to obtain two of its parameters of this sample material 115.
  • the execution units 110a to llOd may be configured to heat, shake, illuminate, sonicate, sample material Analysis fluid such as alcohol or an enzyme to mix or contact to process the sample material 115 to determine the desired parameter.
  • the execution units 110a-llOd may be configured not to perform a plurality of different actions with respect to the sample material 115, but each of the
  • Execution units 110a to llOd perform a specific action or actions with respect to the sample material 115, in which case the sample material 115 or the correspondingly treated sample material 115 of a
  • Execution unit for example, the execution unit 110b is transferred to a further execution unit 110c, where it is processed further and, for example, is transmitted back to the execution unit 110b.
  • a flexible analysis of the sample material 115 can be carried out in cost-effective execution units 110.
  • the analyzer 11O In order to be able to carry out the analysis of the sample material 115 by means of the analyzer 110, the analyzer 11O upright. the corresponding execution units 110a to 110b are designed in order to be able to carry out as many different analysis operations as possible with the same execution units 110a to 110d in order to enable the most flexible possible use in different application scenarios. For this purpose, however, it is necessary that the individual execution unit 110a to 110d or a combination of several of the execution units 110a to 110d be driven with corresponding control commands in order to obtain the information currently required for the analysis
  • Control device 120 first a usage parameter 125 via a
  • the usage parameter 125 may be, for example, a code on a container 133 in which the
  • Sample material 115 is arranged, for example, a laboratory chip, in which a drop of blood is received.
  • this code or usage parameter 125 the control device 120 can be informed, for example, that now an analysis of the blood drop as sample material 115 is to be carried out.
  • this usage parameter 125 can then be transmitted to a loading unit 135 which determines the sequence of activation commands 140 for one or more execution units 110a to 110d, which correspond, for example, to predefined activation commands 140 stored in a command library 145.
  • Each of these drive commands 140 corresponds to information for one of the execution units 110a to 110d to perform a specific action or actions with respect to the sample material 115 (or a correspondingly further processed sample material 115).
  • the drive commands 140 can then be used as a command set by means of a
  • Drive unit 142 are transferred to the respective execution units 110a to llOd, which process the sample material 115 in accordance with these drive commands 140 to analyze the sample material 115.
  • individual can also be used here
  • Execution units 110b or 110c are executed, special, when the respective execution unit 110b or 110c (for example, from
  • the command library 145 can be stored on a memory element of the
  • Analyzer or the control device 120 itself be stored.
  • a command library 145 may also be used, which is wholly or partially outside the control device 120 or the
  • Analyzer 100 is arranged.
  • the command library may be wholly or partially arranged in a memory of a container 133 or stored, which contains the sample material 115 or stored in a computer network, which is configured as a cloud server.
  • An analysis result 150 or analysis result which is obtained, for example, from the respectively affected execution units 110b or 110d after execution of the analysis substeps effected by the corresponding activation commands 140, can then be transmitted back to the control device 120, for example.
  • the control device 120 it is then possible to decide, for example based on further parameters, such as a user parameter 155, which is read in via the read-in interface 130, whether the analysis result 150 is displayed or, for example, transmitted to an external computer unit 160, which is designed as a cloud computer can or may.
  • control commands 140 are read into the control device 120, for example, the manufacturer of the
  • Execution units 110a to llOd provided or by other users of types of the respective execution units 110a to llOd
  • execution units 110a to 110d In order to be able to use the execution units 110a to 110d as flexibly as possible, and to be able to carry out, for example, also analysis sub-steps or a sequence of analysis steps, which are used in the production of the
  • an input interface 165 can also be provided, via which, for example, a protocol 170 containing one or more "new” activation commands 140 is supplied to the analyzer 110, so that this "new"
  • Control command 140 can be stored in the command library 145. In this way, a further flexibility of the use of the command library 145.
  • Analyzer or the respective execution units 110a reach 110b.
  • a location parameter 175 can be read, which represents an operational environment of the analyzer 100.
  • the location parameter 175 represents an operational environment of the analyzer 100.
  • Location parameter 175 indicate that the analyzer 100 is in a Hospital, a doctor's office or a private home user, so that, for example, certain analyzes due to in the
  • analyzer lOOa is not allowed or should not be executed, in fact not be executed.
  • the location parameter 175 indicates that the analyzer is in a doctor's office, it can be prevented that an analysis of the sample material 115 on the
  • an intervention parameter 180 can be read in by the read-in interface 130, which represents an intervention of a user on the execution of the analysis or the sequence of the execution of the activation commands.
  • the user can be used by means of the intervention parameter 180, which is read in, for example, via a human-machine interface HMI to be described in more detail below, in order to effect a cancellation of the execution of the analysis partial steps in the execution units 110a to 110d controlled by the activation commands 140.
  • the intervention parameter 180 it is also conceivable for the intervention parameter 180 to be called up, for example, as specific information for controlling the sequence of a (in particular passive) data carrier (eg an RFID) in the disposable cartridge as a container 133 of the sample material 115. This allows
  • reagent, reagent lot or single cartridge or cartridge lot specific parameters are of interest here. But it can also command parts, whole commands or chains of command as well as meta information on the disk of Cartridge be stored and retrieved accordingly and processed by the analyzer 100 or one or more execution units 110.
  • the RFID as a carrier of the intervention parameter 180 also offers the possibility to mark the cartridge after use by a so-called kill-switch as used (for example as an irreversibly settable flag) in order to prevent reuse.
  • the microfluidic platform for assays i.e., the analyzer 100
  • the control system 120 also allows control of multiple platform analyzers or execution units 110a-110d through a common network or cloud 160.
  • Interface protocol can be seen, which by a general
  • Command library 145 controls or controls hardware components such as execution units 110a-110b in chronological order.
  • the command library 145 is designed so that new (control) commands 140 can be easily added.
  • the dependencies of the instructions 140 are regulated by a rule and specification library which is implemented, for example, as part of the instruction library 145 and which, in the read-out of the drive instructions 140, is based on the consistency of the drive instructions 140 and 140, respectively. the sequence of drive commands 140 for the respective execution unit 110a to llOd is consulted.
  • New elements such as further execution units 110
  • Analyzers or execution units 110 are controlled or controlled.
  • the protocol used for the sequence of activation commands 140 makes it possible to test whether the hardware used, like the execution units 11O, satisfies the test or analysis requirements used. This is important insofar as different hardware versions of devices or execution units 11O are in use on the field. Also, it can be ensured that tests or analyzes, which are only for
  • Analyzer 100 is carried out, for example, in a doctor's office, where the test or the analysis is not allowed, is performed. This control is an important part of the fleet management of the use of the analyzer 100 can be seen.
  • a human interface can be integrated universally and adapted to the application, so that a user, for example, also carries out an analysis
  • condition functions allows a dynamic control of applications or analyzes. No fixed parameters need be measured, but an (analysis) step can for example only be carried out if a certain condition of the sample material or of an element of the execution unit 110 is achieved. So can a system or analyzer can be adapted to environmental conditions. As an example, the temperature is listed here, with a
  • sample material 115 or a component of the execution unit 110 in which a respective analysis sub-step is to be performed may have a certain temperature required to successfully implement the analysis sub-step.
  • a temperature-sensitive step is then carried out, for example, only when the corresponding temperature has been reached.
  • the control system 120 with its policy and general command library 145, speeds the development of new applications or analyzes that reside on the analyzer
  • FIG. 1 the schematic structure and the control mechanism for the system or analyzer 100 are shown.
  • Components 110 should be driven and controlled for a microfluidic assay or analysis at the right time. To ensure this smoothly, they are a control unit or the
  • Control device 120 controlled.
  • the subunits (which are synonymously also referred to as execution units LLO) can be used by the control unit (which is also synonymous as a control device
  • control unit 120 receive signals (as the drive commands 140) but also send data (eg, the analysis result 150). Furthermore, the control unit 120 may also communicate with an external cloud 160. In order to use the analyzer or the analyzer 100 as universally as possible, the control unit 120 is for example loaded with a protocol which contains general commands for controlling the control unit 120. This transforms the Commands 140 corresponding to the language of subunits HOab and controls those.
  • the control unit 120 is responsible for the coordination and control of the individual subunits. Even if a new subunit 110 should be installed in the analyzer 100, then this is controlled via the interface of the control unit 120.
  • Fig. 2 shows a schematic representation of the structure and operation of the loader 135 with a log library 200.
  • the gist of this setup is the use of the library 145 as a collection of allowed and tested instructions 140 for the analyzer 100b. the corresponding
  • Execution Units 110 The instructions 140 are ordered according to functions of the individual subunits 110.
  • This library 145 is universal and any sequence programs, i. Protocols 200 may be assembled from these instructions 140.
  • the requirements 210 describe how which instructions 140 can be combined to a successful flow of analysis.
  • the requirements 210 (engl.
  • Requirements set the allowed parameters and conditions (e.g.
  • the library 145 (or more precisely, the commands 140 stored therein) is ideally written in an enhanced markup language (eg XML, SGML, RSS) which allows new instructions to be successively added to the library 145, taking into account the requirements 210 and Rules 205 are added.
  • an enhanced markup language eg XML, SGML, RSS
  • Protocols 200 are written in an enhanced markup language, while the processing is integrated into the analyzer 100 hardware.
  • Fig. 3 shows a schematic representation of a general structure of the protocol or instruction set 200. This generally consists of two parts. A first part 300 forms a global information part containing the
  • Meta-information that can be retrieved at any time during an assay procedure This includes, for example, what assay (s) to perform on the execution units 11O, patient information, machine request information, and information that may be displayed to the user of the analyzer 100.
  • This information can also be used in the first part 300 to check whether the used machine or the execution unit 11O corresponds to the requirements for the corresponding analyzer 100.
  • This is of interest to medical devices in that the same analyzer 100 can be in an analytical laboratory or as a patient-near analyzer by a general practitioner or at a clinical ward. These have different approvals.
  • An analyzer 100 in the doctor's office would certainly have the option of processing a test or an analysis which is only valid or permissible in the analysis laboratory.
  • the location in a location parameter 170 or a hardware revision (e.g., for which analyzes the analyzer 100 is allowed and for which not) can then be adjusted and possible misuse prevented.
  • an assay or analysis might require specific hardware components as execution unit 119 in analyzer 100, which are only specifically installed in a particular analyzer 100. The presence of these components 100 can be ensured by the meta information in the first part 300.
  • the second part 310 includes, for example, a part of temporary ones
  • Step information which is used as drive commands 140 for the relevant
  • Execution unit llO implemented multiple execution units 110 are. These instructions 140 are successively in orderly sequence in defined time steps by the execution unit or
  • Execution units llOprocessed Thus, the actual recipe or instruction set 200 of the application assay, i. the analysis to be performed. To do this, the instructions 140 are taken out of the library 145 which drive the correct universal subunits 110 at the right time in the right context. Requirements 210 and Rule 205 set the framework again and support the correct application. If timelines are not clear from the beginning, conditions can also be implemented as criteria to fulfill. In this case, a subsequent command 140 is executed only when a certain value within the system (ie the
  • Analyzer 100 standing at least one of the execution units 110) is achieved.
  • the temperature is listed here. A certain step only starts when a subunit 110 configured as a heater has a certain amount
  • control device 120 may have a plurality of subunits.
  • a process unit PU is installed, which operating basic subunits (called processing unit, PU) such as heaters, optics, pneumatics u.a. controls.
  • processing unit PU
  • This process unit PU has internally its own control and already integrated preprocessing of information and commands.
  • Interface definition and new protocol commands 140 can be added modularly as a software package.
  • the handover is governed, for example, in the global part of the protocol 200.
  • HMI Human Machine Interface
  • User 400 interacts with the machine or analyzer 100.
  • the control unit CU of the control device 120 can continuously test whether the protocol or the control commands 140 should be executed, for example, as a command address 200 or the user 400 in the protocol or the process engages the execution of the drive commands 140, in particular, wants to cancel the protocol or the execution of the analysis.
  • user interactions are necessary. This is done via the connection of the user 400 by means of the human-machine interface HMI. Also what is displayed on data and results on a screen, is regulated by the connection of the user by means of the human-machine interface HMI.
  • the global meta information in the protocol 200 makes the connection of the user 400 via the human-machine interfaces HMI application-specific.
  • Fig. 5 shows a schematic block diagram representation of another
  • the same construct of using drive commands 140 may be exploited to provide multiple analyzers or
  • Analyzers 100 can be networked with each other, which can be done for example via an own network or via a cloud 160.
  • the CU of an analyzer 100 is used as the main CU, which processes or Coordinates the analysis of the other CUs so that the overall process runs successfully.
  • the HMI man-machine interface is also controlled by this CU.
  • Fig. 6 shows a flowchart of an embodiment of the present invention
  • the method 600 includes a step 610 of reading in a usage parameter that includes a
  • method 600 includes step 620 of loading a plurality of
  • the method 600 includes a step 630 of driving the at least one
  • an exemplary embodiment comprises a "and / or" link between a first feature and a second feature, then this is to be read so that the embodiment according to one embodiment, both the first feature and the second feature and according to another embodiment either only first feature or only the second feature.

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Abstract

L'invention concerne un procédé (600) de commande d'un dispositif d'analyse (100) destiné à effectuer une analyse d'un échantillon de matière (115). Le procédé (600) comprend une étape de lecture (610) d'un paramètre d'utilisation (125) représentant une analyse à effectuer de l'échantillon de matière (115). En outre, le procédé (600) comprend une étape de chargement (620) d'une pluralité d'instructions de commande (140, 200) destinées à au moins une unité d'exécution (110a, 110b, 100c, 100d) du dispositif d'analyse (100) à partir d'une bibliothèque d'instructions (145). Enfin, le procédé (600) comprend une étape de commande (630) de l'au moins une unité d'exécution (110a, 100b, 110c, 110d) à l'aide des instructions de commande (140, 200) pour analyser l'échantillon de matière (115).
EP19719241.2A 2018-04-20 2019-04-18 Procédé et dispositif de commande d'un dispositif d'analyseur pour effectuer une analyse d'un échantillon de matière Pending EP3782163A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102018206092.4A DE102018206092A1 (de) 2018-04-20 2018-04-20 Verfahren und Vorrichtung zum Ansteuern eines Analysegerätes zur Ausführung einer Analyse eines Probenmaterials
PCT/EP2019/060055 WO2019202062A1 (fr) 2018-04-20 2019-04-18 Procédé et dispositif de commande d'un dispositif d'analyseur pour effectuer une analyse d'un échantillon de matière

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EP3782163A1 true EP3782163A1 (fr) 2021-02-24

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US (1) US20210293779A1 (fr)
EP (1) EP3782163A1 (fr)
CN (1) CN112236828A (fr)
DE (1) DE102018206092A1 (fr)
WO (1) WO2019202062A1 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140370609A1 (en) * 2013-04-05 2014-12-18 Roche Molecular Systems, Inc. Analysis system for a biological sample

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5835749A (en) * 1995-05-05 1998-11-10 Apple Computer, Inc. Method and apparatus for providing dynamically linked libraries
US20020049694A1 (en) * 1998-07-27 2002-04-25 J. Wallace Parce Distributed database for analytical instruments
US8707283B2 (en) * 2007-03-29 2014-04-22 Microsoft Corporation Parallel DLL tree initialization
CL2008003008A1 (es) * 2007-10-12 2009-10-02 Bigtec Private Ltd Un micro dispositivo portatil de reaccion en cadena de polimerasa (pcr) basado en un micro chip de ceramica de coccion conjunta de baja temperatura (ltcc) que comprende camara de reaccion, calentador, control de temperatura del calentador, deteccion optica de interfaz de comunicacion, y el metodo para monitorearlo y controlarlo.
TWI448111B (zh) * 2008-03-18 2014-08-01 Icm Inc Automobile detection and control integration device and method thereof
EP3139222B1 (fr) * 2015-09-04 2022-04-13 F. Hoffmann-La Roche AG Système de gestion de test analytique et procédé
CN109073669B (zh) * 2016-04-22 2022-11-25 贝克顿·迪金森公司 自动化诊断分析仪和用于自动化诊断分析仪的操作的方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140370609A1 (en) * 2013-04-05 2014-12-18 Roche Molecular Systems, Inc. Analysis system for a biological sample

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CN112236828A (zh) 2021-01-15
WO2019202062A1 (fr) 2019-10-24
DE102018206092A1 (de) 2019-10-24

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