EP3773206A1 - Système de mesure pour réaliser des analyses spectroscopiques de tissu vivant - Google Patents
Système de mesure pour réaliser des analyses spectroscopiques de tissu vivantInfo
- Publication number
- EP3773206A1 EP3773206A1 EP19718581.2A EP19718581A EP3773206A1 EP 3773206 A1 EP3773206 A1 EP 3773206A1 EP 19718581 A EP19718581 A EP 19718581A EP 3773206 A1 EP3773206 A1 EP 3773206A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- housing
- measuring system
- radiation
- radiation source
- optical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000005259 measurement Methods 0.000 title claims abstract description 31
- 230000005855 radiation Effects 0.000 claims abstract description 139
- 230000003287 optical effect Effects 0.000 claims abstract description 37
- 230000005540 biological transmission Effects 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 7
- 238000013461 design Methods 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 239000003822 epoxy resin Substances 0.000 claims description 3
- 229920000647 polyepoxide Polymers 0.000 claims description 3
- 239000012080 ambient air Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 230000000007 visual effect Effects 0.000 claims description 2
- 238000011156 evaluation Methods 0.000 abstract description 4
- WEJZHZJJXPXXMU-UHFFFAOYSA-N 2,4-dichloro-1-phenylbenzene Chemical compound ClC1=CC(Cl)=CC=C1C1=CC=CC=C1 WEJZHZJJXPXXMU-UHFFFAOYSA-N 0.000 description 9
- 239000004744 fabric Substances 0.000 description 6
- 238000010438 heat treatment Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000013307 optical fiber Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 2
- 230000003670 easy-to-clean Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 230000001766 physiological effect Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 238000009529 body temperature measurement Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 238000001055 reflectance spectroscopy Methods 0.000 description 1
- 229910000679 solder Inorganic materials 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
- A61B5/14552—Details of sensors specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6825—Hand
- A61B5/6826—Finger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors
- A61B2560/0238—Means for recording calibration data
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
- A61B2560/0247—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
- A61B2560/0252—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using ambient temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
- A61B2562/166—Details of sensor housings or probes; Details of structural supports for sensors the sensor is mounted on a specially adapted printed circuit board
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/18—Shielding or protection of sensors from environmental influences, e.g. protection from mechanical damage
- A61B2562/185—Optical shielding, e.g. baffles
Definitions
- a plurality of LEDs 3a as radiation sources 3 and a photodiode as a reference sensor 6 are arranged.
- the LEDs 3a and the reference sensor 6 are also arranged together in the cavity 8a.
- Via the housing opening 2a of the housing 2 light can enter or leave the cavity 8a in the cavity 8a.
- a shield 9 is provided, by means of which a narrow optical connecting channel 2c is formed between the radiation source 3 and the reference sensor 6.
- the height H of the optical connection channel 2c is an important system parameter.
- the measuring system 1 in FIG. 6 is designed to examine a finger 5 a:
- the temperature sensor 14 a is placed in the cavity 8 a so that the temperature of the surroundings of the LEDs 3 a and of the radiation detector 4 can be determined. It should be noted that it is only a cross section in Figure 6 and the temperature sensor 14a is located at the edge of the housing, so that the channel between LEDs 3a and Reference sensor 6 remains largely free and thus the reference measurement is not affected.
- the temperature measured with the temperature sensor 14a has several causes (radiation of the finger, heat conduction between fingers 5a and housing 2, heat radiation of the LEDs 3a, heating of the housing 2 by the operation of the electrical components).
Abstract
La présente invention concerne un système de mesure (1) pour réaliser des analyses spectroscopiques de tissu vivant comprenant un boîtier (2) qui présente deux ouvertures (2a, 2b) situées sur un côté du boîtier, une source de rayonnement optique (3) agencée dans le boîtier (2) et un détecteur de rayonnement optique (4) agencé dans le boîtier (2), la source de rayonnement optique (3) et le détecteur de rayonnement optique (4) étant respectivement associés à une ouverture de boîtier (2a, 2b) et aucune liaison optique n'étant présente à l'intérieur du boîtier (2) entre la source de rayonnement (3) et le détecteur de rayonnement (4). Le but de l'invention est de minimiser les perturbations internes et externes et/ou de pouvoir les détecter et ainsi d'en tenir compte de manière fiable lors de l'évaluation des résultats de mesure, le système de mesure devant pouvoir être réglé de manière flexible en fonction des différentes personnes et des différents sites d'application et intégré dans d'autres systèmes de mesure. Selon l'invention, un capteur optique de référence (6) est agencé dans le boîtier et un canal de liaison optique directe (2c) consiste à transmettre un signal de référence de la source de rayonnement (3) au capteur de référence (6).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102018002620 | 2018-03-29 | ||
| DE102018003521 | 2018-05-02 | ||
| PCT/EP2019/058070 WO2019185903A1 (fr) | 2018-03-29 | 2019-03-29 | Système de mesure pour réaliser des analyses spectroscopiques de tissu vivant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EP3773206A1 true EP3773206A1 (fr) | 2021-02-17 |
Family
ID=66240050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP19718581.2A Pending EP3773206A1 (fr) | 2018-03-29 | 2019-03-29 | Système de mesure pour réaliser des analyses spectroscopiques de tissu vivant |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP3773206A1 (fr) |
| CN (1) | CN111936049A (fr) |
| WO (1) | WO2019185903A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11723563B1 (en) | 2020-09-11 | 2023-08-15 | Apple Inc. | Correcting for emitted light wavelength variation in blood-oxygen saturation measurements at wearable electronic device |
| CN113476043A (zh) * | 2021-07-01 | 2021-10-08 | 深圳亿杉医疗科技有限公司 | 一种非侵入式传感装置及检测方法、检测仪 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5291884A (en) * | 1991-02-07 | 1994-03-08 | Minnesota Mining And Manufacturing Company | Apparatus for measuring a blood parameter |
| US7630078B1 (en) * | 2005-09-20 | 2009-12-08 | Pacesetter, Inc. | Calibrating implantable optical sensors |
| US8175668B1 (en) * | 2007-10-23 | 2012-05-08 | Pacesetter, Inc. | Implantable multi-wavelength venous oxygen saturation and hematocrit sensor and method |
| US8352008B2 (en) * | 2009-06-10 | 2013-01-08 | Medtronic, Inc. | Active noise cancellation in an optical sensor signal |
| US8634890B2 (en) * | 2009-06-10 | 2014-01-21 | Medtronic, Inc. | Device and method for monitoring of absolute oxygen saturation and tissue hemoglobin concentration |
| JP2011077212A (ja) * | 2009-09-30 | 2011-04-14 | Sumitomo Osaka Cement Co Ltd | 発光装置 |
| US8489164B2 (en) * | 2010-10-27 | 2013-07-16 | Medtronic, Inc. | Monitoring of tissue hemoglobin concentration |
| US10078052B2 (en) | 2014-08-28 | 2018-09-18 | Apple Inc. | Reflective surface treatments for optical sensors |
| EP3313285A4 (fr) * | 2015-06-25 | 2019-03-27 | Fresenius Medical Care Holdings, Inc. | Système de mesure différentielle de lumière directe |
-
2019
- 2019-03-29 EP EP19718581.2A patent/EP3773206A1/fr active Pending
- 2019-03-29 CN CN201980023664.0A patent/CN111936049A/zh active Pending
- 2019-03-29 WO PCT/EP2019/058070 patent/WO2019185903A1/fr active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019185903A1 (fr) | 2019-10-03 |
| CN111936049A (zh) | 2020-11-13 |
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