EP3749454B1 - System for ejecting tips of sampling pipettes with improved ergonomics - Google Patents

System for ejecting tips of sampling pipettes with improved ergonomics Download PDF

Info

Publication number
EP3749454B1
EP3749454B1 EP19728494.6A EP19728494A EP3749454B1 EP 3749454 B1 EP3749454 B1 EP 3749454B1 EP 19728494 A EP19728494 A EP 19728494A EP 3749454 B1 EP3749454 B1 EP 3749454B1
Authority
EP
European Patent Office
Prior art keywords
pipette
ejection
cone
control lever
fixed body
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP19728494.6A
Other languages
German (de)
French (fr)
Other versions
EP3749454A1 (en
Inventor
Hervé MALVOISIN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gilson SAS
Original Assignee
Gilson SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilson SAS filed Critical Gilson SAS
Priority to PL19728494T priority Critical patent/PL3749454T3/en
Publication of EP3749454A1 publication Critical patent/EP3749454A1/en
Application granted granted Critical
Publication of EP3749454B1 publication Critical patent/EP3749454B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/0275Interchangeable or disposable dispensing tips
    • B01L3/0279Interchangeable or disposable dispensing tips co-operating with positive ejection means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/08Ergonomic or safety aspects of handling devices
    • B01L2200/087Ergonomic aspects
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes
    • B01L3/021Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type

Definitions

  • the invention relates to the field of sampling pipettes, also called laboratory pipettes or also liquid transfer pipettes, intended for sampling and dispensing liquid in containers or the like.
  • the invention relates to any type of pipette, mechanical, electronic or hydride, of the single-channel or multi-channel type.
  • the pipettes more preferably concerned by the present invention are mechanical pipettes with manual actuation. These pipettes are intended to be held in the hand by an operator during liquid sampling and dispensing operations. These operations are carried out by setting in motion a control button obtained by the application of an actuating pressure on this same button, via the operator's thumb.
  • the invention may also relate to hybrid pipettes, or even so-called electronic pipettes within which the movement of the piston is generated by a motor receiving an instruction from the operator, following a pressure exerted on a control button.
  • One of the functions provided by the pipettes is the ejection of the sampling tips. This ejection is usually triggered by the operator who presses, with his thumb, on an ejection button located at the top of the pipette, near the control button.
  • the downward movement of the ejection button brings with it the entire ejection system, which, at its lower end, presses on the periphery of a cone fitted on the pipette tip, in order to cause its ejection. .
  • This ejection requires exceeding the friction forces between the cone and its tip. From this In fact, the operator may have to exert a significant force on the ejection button to unmount the sampling cone.
  • the invention thus provides a simple, efficient and inexpensive response, improving the ergonomics of ejection of the sampling cones.
  • the ejection force to be exerted on the button is advantageously smaller than that required with the solutions of the prior art. Consequently, this specificity of multiplying the ejection force, via the control lever, provides ease of use for the operator.
  • the solution proposed by the invention has the advantage of retaining a linear movement of displacement of the control button, which contributes to the overall improvement of the ergonomics associated with the function of ejection of the cones.
  • This type of linear movement also guarantees the solidity of the pipette, since the risk of breakage or damage to the ejection button is extremely low.
  • the invention also has at least any one of the following optional characteristics, taken individually or in combination.
  • control lever is thus articulated at its first end, and resting on the ejection button as well as on the ejection device. Consequently, during an operation of ejecting a cone, the lever pivots while simple presses are observed at the level of its contacts with the button and the ejection device.
  • Another design could for example consist in providing a pivot connection between the second end of the control lever, and the ejection button.
  • the first end of the lever could then be mounted to slide and pivot, in a rail of the pipette part intended to cooperate with this lever.
  • the intermediate portion could be articulated on the cone ejection device, and the two ends of the lever simply resting on the pipette part and the ejection button.
  • connection between the intermediate actuation portion of the control lever, and the cone ejection device is a point sphere-plane connection.
  • This type of connection makes it possible to limit friction as much as possible during pivoting of the control lever. The wear of the parts concerned is thereby advantageously reduced.
  • this type of connection makes it possible to transmit to the ejection device a force always oriented axially, offering great efficiency.
  • the ejection device has an upper portion biased by the elastic return means and intended to be housed in a fixed body forming a handle of the pipette, as well as a lower portion integral with the upper portion and defining an ejection end. cone.
  • the ejection device is intended to be movable in translation relative to the fixed body of the pipette.
  • the subject of the invention is also a sampling pipette comprising such a cone ejection system.
  • the part on which the first end of the control lever is mounted is secured to the fixed body forming the handle of the pipette, or produced in one piece with this fixed body.
  • the part on which the first end of the control lever is mounted is centered on a longitudinal central axis of the pipette, and traversed by a control rod of the pipette.
  • a pivot axis of the first end of the control lever intercepts a longitudinal central axis of the pipette, preferably substantially orthogonally.
  • the pipette has an end-of-travel stop for the ejection button, said stop being secured to the fixed body forming the handle of the pipette, or made in one piece with this fixed body.
  • This stop is preferably made of an elastomeric material.
  • the ejection button projects upwards from the fixed body forming the handle of the pipette.
  • the ejection button is movable in translation relative to the fixed body forming the handle of the pipette, preferably parallel to a longitudinal central axis of the pipette.
  • the pipette is preferably a mechanical pipette, but it could be an electronic or hybrid pipette with such a manual sampling cone ejection system.
  • a mechanical sampling pipette 1 comprising a cone ejection system 2 according to the invention.
  • the pipette 1 has a manually actuated design, i.e. it is intended to be held by the hand of an operator, who, using his thumb 4, is able to actuate the pipette. pipette to generate the dispensation of a liquid which has previously been aspirated.
  • the pipette 1 comprises in the upper part a fixed body forming a handle 6 of the pipette, from which handle opens a control rod 10. At the upper end of this rod 10, the pipette comprises a control button. pipetting control 12, the upper part of which is intended to undergo the pressure of the thumb 4 of the operator.
  • the pipette 1 comprises a removable lower part 14, which ends downwards with a cone-holder tip 16 receiving a consumable 18, also called a sampling cone.
  • the cone ejection system 2 comprises an ejection device 24, of which a lower portion 20 projecting from the handle 6 defines a cone ejection end 22, surrounding the nozzle 16. This ejection end 22 is located opposite the upper end of the cone 18, so as to be able to cause it to be unhooked by pressing on its periphery.
  • the ejection device 24, of which only the lower portion 20 is visible on the figure 1 , is mounted to move in translation with respect to the handle 6 and to the lower part 14, both forming the fixed part 23 of the pipette. It is a translation in a direction parallel to a longitudinal central axis 8 of the pipette, according to which the control rod 10 is also movable in translation within the pipette.
  • the control rod 10 is moreover centered on this axis 8.
  • the ejection system 2 also includes a cone ejection button 25, also controlled by the thumb 4 of the operator.
  • the ejection button 25 is arranged projecting upwardly at the upper end of the handle 6, being offset laterally and axially from the control button 12.
  • the ejection button 25 is mounted to move in translation with respect to the handle. handle 6, also parallel to the direction of the longitudinal central axis 8 of the pipette.
  • this button when the ejection button 25 is actuated downwards by the thumb of the operator as shown schematically on the figure 2 , this button causes the ejection device 24 to descend, in a manner specific to the invention which will be described below.
  • the setting in motion of the lower portion 20 of the device 24 causes a translation of its ejection end 22 along the end piece 16, with the consequence of pressing the cone 18 which then quickly releases from this end piece.
  • it is noted that in the embodiment described and shown in the figures, it is a single-channel pipette carrying a single consumable 18. However, it could be a multichannel pipette carrying several cones, without departing from the scope of the invention.
  • figure 3 represents the system in an idle state of rest, while the figure 4 represents this same system in a state of ejection of the cone, following an action by the operator on the ejection button 25.
  • the ejection button 25 is movably mounted on a guide rail 42 of a fixed assembly 44, formed integrally with the handle 6, or secured to this handle by being fixedly mounted. on this one.
  • the ejection device 24 also comprises an upper portion 21 which is housed in the handle 6.
  • the lower end of the upper portion has a plate 30 on which resilient return means, in the form of a compression spring 32.
  • the other end of the spring bears on a fixed part 34 of the pipette arranged near the junction between the handle and the lower part 14, so as to return the entire device 24 to the upper position.
  • the lower and upper portions 20, 21 of the device 24 are integral with one another, and connected by a rod 36 visible on the figure 4 , which passes through the fixed part 34.
  • a force multiplier element within the ejection system 2, namely a control lever 40.
  • This lever 40 is interposed between the ejection button 25, and the upper portion 21 of the device 24 which it controls. It firstly comprises a first end 40a mounted articulated on a fixed part 46 of the aforementioned assembly 44.
  • This fixed part 46 is centered on the longitudinal central axis 8, and takes the form of a sleeve traversed by the control rod 10.
  • the pivot axis 48 of the first end 40a orthogonally intercepts the longitudinal central axis 8, and it is located offset downward with respect to the ejection button 25, when the latter occupies its inactive position of rest of the figure 3 .
  • the first end 40a can be formed from a single articulated branch, or else take the form of a yoke, the two ears of which are each articulated along the same axis 48 on the fixed part 46. In the latter case, the two ears yoke would be arranged on either side of the fixed part 46, received between these two ears.
  • the lever 40 has, opposite the first end 40a, a second end 40b on which the lower end of the ejection button 25 bears. It may be a connection of the sphere-plane or cylinder-plane type, in order to limit the sliding and the wear which results therefrom during the pivoting of the lever 40.
  • the lever 40 also comprises an intermediate actuating portion 40c, arranged between the two ends 40a, 40b, preferably while being substantially centered relative to the latter.
  • This intermediate portion 40c is provided to actuate the upper portion 21 of the device 24 in translation, by resting on the upper end of this portion 21.
  • a point sphere-plane connection 50 is provided between this intermediate portion 40c and the upper portion 21, for example by providing a truncated sphere 52 within the portion 40c of the control lever.
  • this type of connection makes it possible to transmit to the upper portion 21 an ejection force always oriented axially, offering high efficiency.
  • the truncated sphere can be made on the upper end of the upper portion 21 of the ejection device 24.
  • the second end 40b When system 2 is in its idle idle state of the figure 3 , the second end 40b is located higher than the first end 40a. As the button 25 is actuated downwards, the second end 40b on which it presses is moved downwards, and causes the rotation of the lever 40 about the pivot axis 48. During this rotation , during which the lever 40 passes through a median position in which it is oriented substantially orthogonally to the longitudinal central axis 8, the intermediate portion 40c presses on the upper portion 21 and drives the entire ejection device 24 downwards . This rotation of the lever 40 continues until the system 2 adopts its state of ejection from the figure 4 , wherein the second end 40b is lower than the first end 40a.
  • This ejection position is not marked by an end stop associated with the lever, but by an end stop of the ejection button 25, so as to limit the risk of damaging this lever 40.
  • the stop here takes the form of one or more seals 60 made of elastomeric material, shown in the figure. figure 5 . These seals 60 are carried by the guide rail 42, at a top end thereof, in order to be contacted by a top end 62 of the button forming the pressure zone for the operator. Thus, at the end of the ejection operation, the operator pressing with his thumb on the pressure zone 62 is stopped in his movement by the stop of this same zone 62 on the seals made of elastomeric material 60.
  • the stroke of the ejection button 25 between its two extreme positions is for example of the order of 10 to 20 mm, while the incident stroke of the ejection device 24 is of the order of half that of the button 25 .

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Sampling And Sample Adjustment (AREA)

Description

DOMAINE TECHNIQUETECHNICAL AREA

L'invention se rapporte au domaine des pipettes de prélèvement, également dénommées pipettes de laboratoire ou encore pipettes de transfert de liquide, destinées au prélèvement et à la dispense de liquide dans des récipients ou similaires.The invention relates to the field of sampling pipettes, also called laboratory pipettes or also liquid transfer pipettes, intended for sampling and dispensing liquid in containers or the like.

L'invention concerne tout type de pipette, mécanique, électronique ou hydride, du type monocanal ou à multicanaux.The invention relates to any type of pipette, mechanical, electronic or hydride, of the single-channel or multi-channel type.

Les pipettes plus préférentiellement concernées par la présente invention sont les pipettes mécaniques à actionnement manuel. Ces pipettes sont destinées à être tenues en main par un opérateur durant les opérations de prélèvement et de dispense de liquide. Ces opérations sont réalisées par la mise en mouvement d'un bouton de commande obtenue par l'application d'une pression d'actionnement sur ce même bouton, via le pouce de l'opérateur. Comme évoqué ci-dessus, l'invention peut aussi concerner les pipettes hybrides, ou encore les pipettes dites électroniques au sein desquelles le mouvement du piston est généré par un moteur recevant une consigne de de l'opérateur, suite à une pression exercée sur un bouton de commande.The pipettes more preferably concerned by the present invention are mechanical pipettes with manual actuation. These pipettes are intended to be held in the hand by an operator during liquid sampling and dispensing operations. These operations are carried out by setting in motion a control button obtained by the application of an actuating pressure on this same button, via the operator's thumb. As mentioned above, the invention may also relate to hybrid pipettes, or even so-called electronic pipettes within which the movement of the piston is generated by a motor receiving an instruction from the operator, following a pressure exerted on a control button.

ETAT DE LA TECHNIQUE ANTERIEURESTATE OF THE PRIOR ART

L'une des fonctions procurées par les pipettes réside dans l'éjection des cônes de prélèvement. Cette éjection est habituellement déclenchée par l'opérateur qui appuie, avec son pouce, sur un bouton d'éjection situé en partie supérieure de la pipette, à proximité du bouton de commande.One of the functions provided by the pipettes is the ejection of the sampling tips. This ejection is usually triggered by the operator who presses, with his thumb, on an ejection button located at the top of the pipette, near the control button.

Le déplacement vers le bas du bouton d'éjection entraîne avec lui l'ensemble du système d'éjection, qui, à son extrémité inférieure, appuie sur la périphérie d'un cône emmanché sur l'embout de pipette, afin de provoquer son éjection. Cette éjection nécessite de surpasser les efforts de friction entre le cône et son embout. De ce fait, l'opérateur peut avoir à déployer un effort conséquent sur le bouton d'éjection pour désemmancher le cône de prélèvement.The downward movement of the ejection button brings with it the entire ejection system, which, at its lower end, presses on the periphery of a cone fitted on the pipette tip, in order to cause its ejection. . This ejection requires exceeding the friction forces between the cone and its tip. From this In fact, the operator may have to exert a significant force on the ejection button to unmount the sampling cone.

Même si cette solution est largement répandue sur les pipettes connues de l'art antérieur, il subsiste un besoin d'optimisation de l'ergonomie associée à la fonction d'éjection des cônes de prélèvement.Even if this solution is widely used in the pipettes known from the prior art, there remains a need for optimizing the ergonomics associated with the function of ejecting the sampling cones.

Les documents WO 01/76752 , FR 3 040 896 et FR 2 980 123 décrivent des exemples connus de pipettes comprenant des systèmes d'éjection de cône.The documents WO 01/76752 , FR 3,040,896 and FR 2 980 123 describe known examples of pipettes comprising cone ejection systems.

EXPOSÉ DE L'INVENTIONDISCLOSURE OF THE INVENTION

Pour répondre au moins partiellement au besoin identifié ci-dessus, l'invention a pour objet un système d'éjection de cône pour pipette de prélèvement, le système comprenant :

  • un bouton d'éjection de cône destiné à être déplacé en translation par le pouce d'un opérateur ;
  • un dispositif d'éjection de cône ;
  • des moyens élastiques de rappel permettant de rappeler le dispositif d'éjection de cône dans une position haute.
    Selon l'invention, le système comprend de plus un levier de commande du dispositif d'éjection, le levier de commande comportant :
  • une première extrémité destinée à être montée sur une pièce de la pipette ;
  • une seconde extrémité coopérant avec ledit bouton d'éjection, de façon à être sollicitée par celui-ci ;
  • une portion intermédiaire d'actionnement du dispositif d'éjection de cône.
To at least partially meet the need identified above, the subject of the invention is a cone ejection system for a sampling pipette, the system comprising:
  • a cone ejection button intended to be moved in translation by the thumb of an operator;
  • a cone ejection device;
  • elastic return means making it possible to return the cone ejection device to a high position.
    According to the invention, the system further comprises a control lever for the ejection device, the control lever comprising:
  • a first end intended to be mounted on a part of the pipette;
  • a second end cooperating with said ejection button, so as to be urged by the latter;
  • an intermediate actuation portion of the cone ejection device.

L'invention apporte ainsi une réponse simple, performante et peu coûteuse, améliorant l'ergonomie d'éjection des cônes de prélèvement. En effet, grâce à l'utilisation particulière du levier de commande, l'effort d'éjection à exercer sur le bouton s'avère avantageusement plus faible que celui requis avec les solutions de l'art antérieur. Par conséquent, cette spécificité de démultiplication de l'effort d'éjection, via le levier de commande, procure un confort d'utilisation pour l'opérateur.The invention thus provides a simple, efficient and inexpensive response, improving the ergonomics of ejection of the sampling cones. Indeed, thanks to the particular use of the control lever, the ejection force to be exerted on the button is advantageously smaller than that required with the solutions of the prior art. Consequently, this specificity of multiplying the ejection force, via the control lever, provides ease of use for the operator.

De plus, la solution proposée par l'invention présente l'avantage de conserver un mouvement linéaire de déplacement du bouton de commande, qui participe à l'amélioration globale de l'ergonomie associée à la fonction d'éjection des cônes. Ce type de déplacement linéaire garantit par ailleurs la solidité de la pipette, puisque les risques de casse ou d'endommagement du bouton d'éjection s'avèrent extrêmement faibles.In addition, the solution proposed by the invention has the advantage of retaining a linear movement of displacement of the control button, which contributes to the overall improvement of the ergonomics associated with the function of ejection of the cones. This type of linear movement also guarantees the solidity of the pipette, since the risk of breakage or damage to the ejection button is extremely low.

L'invention présente par ailleurs au moins l'une quelconque des caractéristiques optionnelles suivantes, prises isolément ou en combinaison.The invention also has at least any one of the following optional characteristics, taken individually or in combination.

De préférence, le système d'éjection est conçu de la manière suivante :

  • la première extrémité du levier de commande est montée articulée sur la pièce de la pipette ;
  • le bouton d'éjection est en appui sur la seconde extrémité du levier de commande ;
  • la portion intermédiaire d'actionnement du levier de commande est en appui sur le dispositif d'éjection de cône.
Preferably, the ejection system is designed as follows:
  • the first end of the control lever is mounted articulated on the part of the pipette;
  • the ejection button is pressed on the second end of the control lever;
  • the intermediate actuation portion of the control lever bears on the cone ejection device.

Dans cette réalisation préférée, le levier de commande est ainsi articulé à sa première extrémité, et en appui sur le bouton d'éjection ainsi que sur le dispositif d'éjection. Par conséquent, au cours d'une opération d'éjection d'un cône, le levier pivote tandis que de simples appuis sont observés au niveau de ses contacts avec le bouton et le dispositif d'éjection.In this preferred embodiment, the control lever is thus articulated at its first end, and resting on the ejection button as well as on the ejection device. Consequently, during an operation of ejecting a cone, the lever pivots while simple presses are observed at the level of its contacts with the button and the ejection device.

Une autre conception pourrait par exemple consister à prévoir une liaison pivot entre la seconde extrémité du levier de commande, et le bouton d'éjection. Dans un tel cas couvert par l'invention, la première extrémité du levier pourrait alors être montée glissante et pivotante, dans un rail de la pièce de pipette destinée à coopérer avec ce levier. De manière analogue, la portion intermédiaire pourrait être articulée sur le dispositif d'éjection de cône, et les deux extrémités du levier simplement en appui sur la pièce de pipette et le bouton d'éjection.Another design could for example consist in providing a pivot connection between the second end of the control lever, and the ejection button. In such a case covered by the invention, the first end of the lever could then be mounted to slide and pivot, in a rail of the pipette part intended to cooperate with this lever. Similarly, the intermediate portion could be articulated on the cone ejection device, and the two ends of the lever simply resting on the pipette part and the ejection button.

De préférence, la liaison entre la portion intermédiaire d'actionnement du levier de commande, et le dispositif d'éjection de cône, est une liaison ponctuelle sphère-plan. Ce type de liaison permet de limiter au mieux les frottements lors du pivotement du levier de commande. L'usure des pièces concernées s'en trouve avantageusement réduite. En outre, ce type de liaison permet de transmettre au dispositif d'éjection un effort orienté toujours axialement, offrant une grande efficacité.Preferably, the connection between the intermediate actuation portion of the control lever, and the cone ejection device, is a point sphere-plane connection. This type of connection makes it possible to limit friction as much as possible during pivoting of the control lever. The wear of the parts concerned is thereby advantageously reduced. In addition, this type of connection makes it possible to transmit to the ejection device a force always oriented axially, offering great efficiency.

Le dispositif d'éjection présente une portion haute sollicitée par les moyens élastiques de rappel et destinée à être logée dans un corps fixe formant une poignée de la pipette, ainsi qu'une portion basse solidaire de la portion haute et définissant une extrémité d'éjection de cône.The ejection device has an upper portion biased by the elastic return means and intended to be housed in a fixed body forming a handle of the pipette, as well as a lower portion integral with the upper portion and defining an ejection end. cone.

Le dispositif d'éjection est destiné à être mobile en translation par rapport au corps fixe de la pipette.The ejection device is intended to be movable in translation relative to the fixed body of the pipette.

L'invention a également pour objet une pipette de prélèvement comprenant un tel système d'éjection de cône.The subject of the invention is also a sampling pipette comprising such a cone ejection system.

De préférence, la pièce sur laquelle est montée la première extrémité du levier de commande est solidarisée au corps fixe formant la poignée de la pipette, ou réalisée monobloc avec ce corps fixe.Preferably, the part on which the first end of the control lever is mounted is secured to the fixed body forming the handle of the pipette, or produced in one piece with this fixed body.

De préférence, la pièce sur laquelle est montée la première extrémité du levier de commande est centrée sur un axe central longitudinal de la pipette, et traversée par une tige de commande de la pipette.Preferably, the part on which the first end of the control lever is mounted is centered on a longitudinal central axis of the pipette, and traversed by a control rod of the pipette.

Préférentiellement, un axe de pivotement de la première extrémité du levier de commande intercepte un axe central longitudinal de la pipette, de préférence sensiblement orthogonalement.Preferably, a pivot axis of the first end of the control lever intercepts a longitudinal central axis of the pipette, preferably substantially orthogonally.

La pipette présente une butée de fin de course pour le bouton d'éjection, ladite butée étant solidarisée au corps fixe formant la poignée de la pipette, ou réalisée monobloc avec ce corps fixe. Cette butée est préférentiellement réalisée en matériau élastomère.The pipette has an end-of-travel stop for the ejection button, said stop being secured to the fixed body forming the handle of the pipette, or made in one piece with this fixed body. This stop is preferably made of an elastomeric material.

De préférence, le bouton d'éjection fait saillie vers le haut du corps fixe formant la poignée de la pipette.Preferably, the ejection button projects upwards from the fixed body forming the handle of the pipette.

Préférentiellement, le bouton d'éjection est mobile en translation par rapport au corps fixe formant la poignée de la pipette, de préférence parallèlement à un axe central longitudinal de la pipette.Preferably, the ejection button is movable in translation relative to the fixed body forming the handle of the pipette, preferably parallel to a longitudinal central axis of the pipette.

Enfin, la pipette est de préférence une pipette mécanique, mais elle pourrait être une pipette électronique ou hybride avec un tel système manuel d'éjection de cône de prélèvement.Finally, the pipette is preferably a mechanical pipette, but it could be an electronic or hybrid pipette with such a manual sampling cone ejection system.

D'autres avantages et caractéristiques de l'invention apparaîtront dans la description détaillée non limitative ci-dessous.Other advantages and characteristics of the invention will appear in the detailed non-limiting description below.

BRÈVE DESCRIPTION DES DESSINSBRIEF DESCRIPTION OF THE DRAWINGS

Cette description sera faite au regard des dessins annexés parmi lesquels ;

  • la figure 1 représente une vue de côté d'une pipette de prélèvement selon l'invention, avec son système d'éjection de cône dans un état inactif de repos ;
  • la figure 2 est une vue similaire à la précédente, avec le système d'éjection de cône dans un état d'éjection ;
  • la figure 3 représente une vue plus détaillée du système d'éjection de cône, avec son bouton dans une position inactive de repos ;
  • la figure 4 est une vue similaire à la précédente, avec le bouton dans une position d'éjection du cône ; et
  • la figure 5 est une vue partielle agrandie de celle de la figure 4, montrant plus particulièrement la butée de fin de course associée au bouton d'éjection.
This description will be made with reference to the accompanying drawings, among which;
  • the figure 1 shows a side view of a sampling pipette according to the invention, with its cone ejection system in an inactive state of rest;
  • the figure 2 is a view similar to the previous one, with the cone ejection system in an ejection state;
  • the figure 3 shows a more detailed view of the cone ejection system, with its button in an inactive rest position;
  • the figure 4 is a view similar to the previous one, with the button in a position of ejection of the cone; and
  • the figure 5 is an enlarged partial view of that of the figure 4 , showing more particularly the end stop associated with the ejection button.

EXPOSÉ DÉTAILLÉ DE MODES DE RÉALISATION PRÉFÉRÉSDETAILED PRESENTATION OF PREFERRED EMBODIMENTS

En référence à la figure 1, il est représenté une pipette de prélèvement mécanique 1, comprenant un système 2 d'éjection de cône selon l'invention. La pipette 1 présente une conception à actionnement manuel, c'est-à-dire qu'elle est destinée à être tenue par la main d'un opérateur, qui, à l'aide de son pouce 4, est capable d'actionner la pipette pour engendrer la dispense d'un liquide qui a préalablement été aspiré.With reference to the figure 1 , there is shown a mechanical sampling pipette 1, comprising a cone ejection system 2 according to the invention. The pipette 1 has a manually actuated design, i.e. it is intended to be held by the hand of an operator, who, using his thumb 4, is able to actuate the pipette. pipette to generate the dispensation of a liquid which has previously been aspirated.

Plus précisément, la pipette 1 comprend en partie supérieure un corps fixe formant une poignée 6 de la pipette, poignée de laquelle débouche une tige de commande 10. A l'extrémité haute de cette tige 10, la pipette comporte un bouton de commande de pipetage 12 dont la partie supérieure est destinée à subir la pression du pouce 4 de l'opérateur.More precisely, the pipette 1 comprises in the upper part a fixed body forming a handle 6 of the pipette, from which handle opens a control rod 10. At the upper end of this rod 10, the pipette comprises a control button. pipetting control 12, the upper part of which is intended to undergo the pressure of the thumb 4 of the operator.

Sous la poignée 6, la pipette 1 comporte une partie basse 14 amovible, qui se termine vers la bas par un embout porte-cône 16 recevant un consommable 18, également dénommé cône de prélèvement. Le système d'éjection de cône 2 comporte un dispositif d'éjection 24, dont une portion basse 20 faisant saillie de la poignée 6 définit une extrémité d'éjection de cône 22, entourant l'embout 16. Cette extrémité d'éjection 22 se situe en regard de l'extrémité haute du cône 18, de manière à pouvoir provoquer son désemmanchement par appui sur sa périphérie.Under the handle 6, the pipette 1 comprises a removable lower part 14, which ends downwards with a cone-holder tip 16 receiving a consumable 18, also called a sampling cone. The cone ejection system 2 comprises an ejection device 24, of which a lower portion 20 projecting from the handle 6 defines a cone ejection end 22, surrounding the nozzle 16. This ejection end 22 is located opposite the upper end of the cone 18, so as to be able to cause it to be unhooked by pressing on its periphery.

Le dispositif d'éjection 24, dont seule la portion basse 20 est visible sur la figure 1, est monté mobile en translation par rapport à la poignée 6 et à la partie basse 14, formant tous les deux la partie fixe 23 de la pipette. Il s'agit d'une translation selon une direction parallèle à un axe central longitudinal 8 de la pipette, selon lequel la tige de commande 10 est également mobile en translation au sein de la pipette. La tige de commande 10 est d'ailleurs centrée sur cet axe 8.The ejection device 24, of which only the lower portion 20 is visible on the figure 1 , is mounted to move in translation with respect to the handle 6 and to the lower part 14, both forming the fixed part 23 of the pipette. It is a translation in a direction parallel to a longitudinal central axis 8 of the pipette, according to which the control rod 10 is also movable in translation within the pipette. The control rod 10 is moreover centered on this axis 8.

Le système d'éjection 2 comporte par ailleurs un bouton d'éjection de cône 25, également commandé par le pouce 4 de l'opérateur. Le bouton d'éjection 25 est agencé en saillie vers le haut à l'extrémité haute de la poignée 6, en étant décalé latéralement et axialement du bouton de commande 12. Le bouton d'éjection 25 est monté mobile en translation par rapport à la poignée 6, également parallèlement à la direction de l'axe central longitudinal 8 de la pipette.The ejection system 2 also includes a cone ejection button 25, also controlled by the thumb 4 of the operator. The ejection button 25 is arranged projecting upwardly at the upper end of the handle 6, being offset laterally and axially from the control button 12. The ejection button 25 is mounted to move in translation with respect to the handle. handle 6, also parallel to the direction of the longitudinal central axis 8 of the pipette.

Ainsi, lorsque le bouton d'éjection 25 est actionné vers le bas par le pouce de l'opérateur comme cela est schématisé sur la figure 2, ce bouton provoque la descente du dispositif d'éjection 24, d'une manière spécifique à l'invention qui sera décrite ci-après. La mise en mouvement de la portion basse 20 du dispositif 24 provoque une translation de son extrémité d'éjection 22 le long de l'embout 16, avec pour conséquence l'appui sur le cône 18 qui se désemmanche alors rapidement de cet embout. A cet égard, il est noté que dans le mode de réalisation décrit et représenté sur les figures, il s'agit d'une pipette monocanal portant un unique consommable 18. Cependant, il pourrait s'agir d'une pipette multicanaux portant plusieurs cônes, sans sortir du cadre de l'invention.Thus, when the ejection button 25 is actuated downwards by the thumb of the operator as shown schematically on the figure 2 , this button causes the ejection device 24 to descend, in a manner specific to the invention which will be described below. The setting in motion of the lower portion 20 of the device 24 causes a translation of its ejection end 22 along the end piece 16, with the consequence of pressing the cone 18 which then quickly releases from this end piece. In this regard, it is noted that in the embodiment described and shown in the figures, it is a single-channel pipette carrying a single consumable 18. However, it could be a multichannel pipette carrying several cones, without departing from the scope of the invention.

En référence à présent aux figures 3 et 4, il est représenté de manière plus détaillée le système d'éjection 2. La figure 3 représente le système dans un état inactif de repos, tandis que la figure 4 représente ce même système dans un état d'éjection du cône, suite à une action de l'opérateur sur le bouton d'éjection 25.Referring now to figures 3 and 4 , the ejection system 2 is shown in more detail. figure 3 represents the system in an idle state of rest, while the figure 4 represents this same system in a state of ejection of the cone, following an action by the operator on the ejection button 25.

Sur ces figures, il est tout d'abord noté que le bouton d'éjection 25 est monté mobile sur un rail de guidage 42 d'un ensemble fixe 44, formé monobloc avec la poignée 6, ou solidarisé à cette poignée en étant monté fixement sur celle-ci.In these figures, it is firstly noted that the ejection button 25 is movably mounted on a guide rail 42 of a fixed assembly 44, formed integrally with the handle 6, or secured to this handle by being fixedly mounted. on this one.

Outre la portion basse 14, le dispositif d'éjection 24 comporte également une portion haute 21 qui est logée dans la poignée 6. L'extrémité basse de la portion haute présente une platine 30 sur laquelle appuient des moyens élastiques de rappel, en forme de ressort de compression 32. L'autre extrémité du ressort appuie sur une pièce fixe 34 de la pipette agencée à proximité de la jonction entre la poignée et la partie basse 14, de manière à rappeler l'ensemble du dispositif 24 en position haute. En effet, les portions basse et haute 20, 21 du dispositif 24 sont solidaires l'une de l'autre, et reliées par une tige 36 visible sur la figure 4, qui traverse la pièce fixe 34.In addition to the lower portion 14, the ejection device 24 also comprises an upper portion 21 which is housed in the handle 6. The lower end of the upper portion has a plate 30 on which resilient return means, in the form of a compression spring 32. The other end of the spring bears on a fixed part 34 of the pipette arranged near the junction between the handle and the lower part 14, so as to return the entire device 24 to the upper position. Indeed, the lower and upper portions 20, 21 of the device 24 are integral with one another, and connected by a rod 36 visible on the figure 4 , which passes through the fixed part 34.

L'une des particularités de l'invention réside dans la présence d'un élément démultiplicateur de force au sein du système d'éjection 2, à savoir un levier de commande 40. Ce levier 40 est interposé entre le bouton d'éjection 25, et la portion haute 21 du dispositif 24 qu'il commande. Il comporte tout d'abord une première extrémité 40a montée articulée sur une pièce fixe 46 de l'ensemble 44 précité. Cette pièce fixe 46 est centrée sur l'axe central longitudinal 8, et prend la forme d'un manchon traversé par la tige de commande 10. L'axe de pivotement 48 de la première extrémité 40a intercepte orthogonalement l'axe central longitudinal 8, et il se situe décalé vers le bas par rapport au bouton d'éjection 25, lorsque celui-ci occupe sa position inactive de repos de la figure 3.One of the particularities of the invention lies in the presence of a force multiplier element within the ejection system 2, namely a control lever 40. This lever 40 is interposed between the ejection button 25, and the upper portion 21 of the device 24 which it controls. It firstly comprises a first end 40a mounted articulated on a fixed part 46 of the aforementioned assembly 44. This fixed part 46 is centered on the longitudinal central axis 8, and takes the form of a sleeve traversed by the control rod 10. The pivot axis 48 of the first end 40a orthogonally intercepts the longitudinal central axis 8, and it is located offset downward with respect to the ejection button 25, when the latter occupies its inactive position of rest of the figure 3 .

La première extrémité 40a peut être formée d'une seule branche articulée, ou bien prendre la forme d'une chape dont les deux oreilles seraient chacune articulée selon le même axe 48 sur la pièce fixe 46. Dans ce dernier cas, les deux oreilles de chape seraient agencées de part et d'autre de la pièce fixe 46, reçue entre ces deux oreilles.The first end 40a can be formed from a single articulated branch, or else take the form of a yoke, the two ears of which are each articulated along the same axis 48 on the fixed part 46. In the latter case, the two ears yoke would be arranged on either side of the fixed part 46, received between these two ears.

Le levier 40 présente, à l'opposé de la première extrémité 40a, une seconde extrémité 40b sur laquelle l'extrémité basse du bouton d'éjection 25 est en appui. Il peut s'agir d'une liaison du type sphère-plan ou cylindre-plan, afin de limiter les glissements et les usures qui en découlent lors du pivotement du levier 40.The lever 40 has, opposite the first end 40a, a second end 40b on which the lower end of the ejection button 25 bears. It may be a connection of the sphere-plane or cylinder-plane type, in order to limit the sliding and the wear which results therefrom during the pivoting of the lever 40.

Enfin, le levier 40 comporte également une portion intermédiaire d'actionnement 40c, agencée entre les deux extrémités 40a, 40b, de préférence en étant sensiblement centrée par rapport à celles-ci. Cette portion intermédiaire 40c est prévue pour actionner en translation la portion haute 21 du dispositif 24, par appui sur l'extrémité haute de cette portion 21. Pour ce faire, il est prévu une liaison ponctuelle sphère-plan 50 entre cette portion intermédiaire 40c et la portion haute 21, par exemple en prévoyant une sphère tronquée 52 au sein de la portion 40c du levier de commande. En outre, ce type de liaison permet de transmettre à la portion haute 21 un effort d'éjection orienté toujours axialement, offrant une grande efficacité.Finally, the lever 40 also comprises an intermediate actuating portion 40c, arranged between the two ends 40a, 40b, preferably while being substantially centered relative to the latter. This intermediate portion 40c is provided to actuate the upper portion 21 of the device 24 in translation, by resting on the upper end of this portion 21. To do this, a point sphere-plane connection 50 is provided between this intermediate portion 40c and the upper portion 21, for example by providing a truncated sphere 52 within the portion 40c of the control lever. In addition, this type of connection makes it possible to transmit to the upper portion 21 an ejection force always oriented axially, offering high efficiency.

Alternativement, toujours pour limiter les usures des pièces en présence, la sphère tronquée peut être pratiquée sur l'extrémité haute de la portion haute 21 du dispositif d'éjection 24.Alternatively, still to limit the wear of the parts present, the truncated sphere can be made on the upper end of the upper portion 21 of the ejection device 24.

Lorsque le système 2 est dans son état inactif de repos de la figure 3, la seconde extrémité 40b se trouve plus haute que la première extrémité 40a. Au fur et à mesure que le bouton 25 est actionné vers le bas, la seconde extrémité 40b sur laquelle il appuie est déplacée vers le bas, et provoque la rotation du levier 40 autour de l'axe de pivotement 48. Au cours de cette rotation, durant laquelle le levier 40 passe par une position médiane dans laquelle il est orienté sensiblement orthogonalement à l'axe central longitudinal 8, la portion intermédiaire 40c appuie sur la portion haute 21 et entraîne l'ensemble du dispositif d'éjection 24 vers le bas. Cette rotation du levier 40 se poursuit jusqu'à ce que le système 2 adopte son état d'éjection de la figure 4, dans lequel la seconde extrémité 40b se trouve plus basse que la première extrémité 40a.When system 2 is in its idle idle state of the figure 3 , the second end 40b is located higher than the first end 40a. As the button 25 is actuated downwards, the second end 40b on which it presses is moved downwards, and causes the rotation of the lever 40 about the pivot axis 48. During this rotation , during which the lever 40 passes through a median position in which it is oriented substantially orthogonally to the longitudinal central axis 8, the intermediate portion 40c presses on the upper portion 21 and drives the entire ejection device 24 downwards . This rotation of the lever 40 continues until the system 2 adopts its state of ejection from the figure 4 , wherein the second end 40b is lower than the first end 40a.

Cette position d'éjection n'est pas marquée par une butée de fin de course associée au levier, mais par une butée de fin de course du bouton d'éjection 25, de manière à limiter les risques d'endommagement de ce levier 40. La butée prend ici la forme d'un ou plusieurs joints 60 en matériau élastomère, représentés sur la figure 5. Ces joints 60 sont portés par le rail de guidage 42, à une extrémité haute de celui-ci, afin d'être contactés par une extrémité haute 62 du bouton formant la zone de pression pour l'opérateur. Ainsi, en fin d'opération d'éjection, l'opérateur appuyant avec son pouce sur la zone de pression 62 est stoppé dans son mouvement par la butée de cette même zone 62 sur les joints en matériau élastomère 60.This ejection position is not marked by an end stop associated with the lever, but by an end stop of the ejection button 25, so as to limit the risk of damaging this lever 40. The stop here takes the form of one or more seals 60 made of elastomeric material, shown in the figure. figure 5 . These seals 60 are carried by the guide rail 42, at a top end thereof, in order to be contacted by a top end 62 of the button forming the pressure zone for the operator. Thus, at the end of the ejection operation, the operator pressing with his thumb on the pressure zone 62 is stopped in his movement by the stop of this same zone 62 on the seals made of elastomeric material 60.

La course du bouton d'éjection 25 entre ses deux positions extrêmes est par exemple de l'ordre de 10 à 20 mm, tandis que la course incidente du dispositif d'éjection 24 est de l'ordre de la moitié de celle du bouton 25.The stroke of the ejection button 25 between its two extreme positions is for example of the order of 10 to 20 mm, while the incident stroke of the ejection device 24 is of the order of half that of the button 25 .

Bien entendu, diverses modifications peuvent être apportées par l'homme du métier à l'invention qui vient d'être décrite, uniquement à titre d'exemples non limitatifs, et dont la portée est définie par les revendications annexées.Of course, various modifications can be made by those skilled in the art to the invention which has just been described, solely by way of non-limiting examples, and the scope of which is defined by the appended claims.

Claims (14)

  1. A cone ejection system (2) for a collection pipette, the system comprising:
    - a cone ejection knob (25) for being translationally moved by an operator's thumb (4);
    - a cone ejection device (24);
    - elastic return means (32) capable of returning the cone ejection device (24) into a high position,
    characterised in that it further comprises a control lever (40) for controlling the ejection device (24), the control lever including:
    - a first end (40a) for being mounted onto a piece (46) of the pipette;
    - a second end (40b) cooperating with said ejection knob (25), so as to be biased by the same;
    - an intermediate portion (40c) for actuating the ejection device (24).
  2. The ejection system according to claim 1, characterised in that:
    - the first end (40a) of the control lever(40) is hingedly mounted onto the piece (46) of the pipette;
    - the ejection knob (25) is bearing on the second end (40b) of the control lever (40);
    - the intermediate portion (40c) for actuating the control lever (40) is bearing on the cone ejection device (24).
  3. The ejection system according to claim 1 or claim 2, characterised in that the connection between the intermediate portion (40c) for actuating the control lever (40), and the cone ejection device (24), is a sphere-plane point connection (50).
  4. The ejection system according to any of the preceding claims, characterised in that the ejection device (24) has a high portion (21) biased by the elastic return means (32) and for being housed in a fixed body forming a handle (6) of the pipette, as well as a low portion (20) integral with the high portion and defining a cone ejection end (22).
  5. The ejection system according to the preceding claim, characterised in that the ejection device (24) is to be translationally movable with respect to the fixed body of the pipette.
  6. A collection pipette (1) comprising a cone ejection system (2) according to any of the preceding claims.
  7. The pipette according to claim 6, characterised in that the piece (46) onto which the first end (40a) of the control lever (40) is mounted is secured to the fixed body forming the handle (6) of the pipette, or made as a single piece with this fixed body.
  8. The pipette according to claim 6 or claim 7, characterised in that the piece (46) onto which the first end (40a) of the control lever (40) is mounted is centred on a longitudinal central axis (8) of the pipette, and has a control rod (10) of the pipette therethrough.
  9. The pipette according to any of claims 6 to 8, characterised in that a pivot axis (48) of the first end (40a) of the control lever (40) intersects a longitudinal central axis (8) of the pipette, preferably substantially orthogonally.
  10. The pipette according to any of claims 6 to 9, characterised in that it has limit stop (60) for the ejection knob (25), said stop being secured to the fixed body forming the handle (6) of the pipette, or made as a single piece with this fixed body.
  11. The pipette according to claim 10, characterised in that the stop (60) is made of an elastomeric material.
  12. The pipette according to any of claims 6 to 11, characterised in that the ejection knob (25) projects upwardly from the fixed body forming the handle (6) of the pipette.
  13. The pipette according to any of claims 6 to 12, characterised in that the ejection knob (25) is translationally movable with respect to the fixed body forming the handle (6) of the pipette, preferably in parallel to a longitudinal central axis (8) of the pipette.
  14. The pipette according to any of claims 6 to 13, characterised in that it is a mechanical pipette.
EP19728494.6A 2018-05-07 2019-05-03 System for ejecting tips of sampling pipettes with improved ergonomics Active EP3749454B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL19728494T PL3749454T3 (en) 2018-05-07 2019-05-03 System for ejecting tips of sampling pipettes with improved ergonomics

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1853943A FR3080783B1 (en) 2018-05-07 2018-05-07 CONE EJECTION SYSTEM WITH IMPROVED ERGONOMICS FOR PIPETTE
PCT/FR2019/051023 WO2019215405A1 (en) 2018-05-07 2019-05-03 System for ejecting tips of sampling pipettes with improved ergonomics

Publications (2)

Publication Number Publication Date
EP3749454A1 EP3749454A1 (en) 2020-12-16
EP3749454B1 true EP3749454B1 (en) 2021-11-10

Family

ID=63080087

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19728494.6A Active EP3749454B1 (en) 2018-05-07 2019-05-03 System for ejecting tips of sampling pipettes with improved ergonomics

Country Status (10)

Country Link
US (1) US11845076B2 (en)
EP (1) EP3749454B1 (en)
JP (1) JP7261819B2 (en)
KR (1) KR20210006351A (en)
CN (1) CN111356531B (en)
CA (1) CA3098923A1 (en)
ES (1) ES2905730T3 (en)
FR (1) FR3080783B1 (en)
PL (1) PL3749454T3 (en)
WO (1) WO2019215405A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3128889B1 (en) * 2021-11-09 2023-09-29 Gilson Sas POSITIVE DISPLACEMENT SAMPLING DEVICE, DESIGNED TO IMPROVE THE GRIP OF THE PISTON OF A PISTON-CAPILLARY SYSTEM
CN115283035B (en) * 2022-08-29 2024-04-30 香港中文大学深港创新研究院(福田) Sampling and dripping method of hand-held automatic liquid preparation gun

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI921765A0 (en) * 1992-04-21 1992-04-21 Labsystems Oy MED EN SPETSAVLAEGSNARE FOERSEDD PIPETT.
FR2807340B1 (en) * 2000-04-07 2002-12-06 Gilson Sa PIPETTE FOR TAKING LIQUID SAMPLES WITH CONE EJECTOR MECHANISM
FIU20010274U0 (en) * 2001-07-06 2001-07-06 Biohit Oyj The suction device
PL200761B1 (en) * 2003-07-24 2009-02-27 Pz Htl Spo & Lstrok Ka Akcyjna Pipette replaceable tip ejector unit
US20090071267A1 (en) * 2007-09-17 2009-03-19 Greg Mathus Pipette tip ejection mechanism
PL220934B1 (en) * 2009-08-28 2016-01-29 PZ HTL Spółka Akcyjna Mechanical pipette with adjustable value of the volume of drawn liquid
FR2980123B1 (en) * 2011-09-19 2013-10-11 Gilson Sas POSITIVE DISPLACEMENT PIPETTE HAVING AN IMPROVED EJECTION FUNCTION
WO2016030978A1 (en) * 2014-08-27 2016-03-03 株式会社 エー・アンド・デイ Stand for pipette
FR3040896B1 (en) * 2015-09-15 2017-10-13 Gilson Sas PRESSURE PIPETTE COMPRISING A DOUBLE-FUNCTION CONTROL MEMBER FOR CONE EJECTION AND UNLOCKING OF THE VOLUME ADJUSTMENT SYSTEM
CN205361387U (en) * 2016-01-26 2016-07-06 深圳市爱纳多电子商务有限公司 Imbibition handle

Also Published As

Publication number Publication date
CA3098923A1 (en) 2019-11-14
US20210106986A1 (en) 2021-04-15
FR3080783A1 (en) 2019-11-08
WO2019215405A1 (en) 2019-11-14
PL3749454T3 (en) 2022-02-28
FR3080783B1 (en) 2020-05-22
US11845076B2 (en) 2023-12-19
EP3749454A1 (en) 2020-12-16
CN111356531A (en) 2020-06-30
CN111356531B (en) 2022-06-03
JP2021522993A (en) 2021-09-02
JP7261819B2 (en) 2023-04-20
ES2905730T3 (en) 2022-04-11
KR20210006351A (en) 2021-01-18

Similar Documents

Publication Publication Date Title
EP3349901B1 (en) Sampling pipette comprising a control member with double function for ejecting a cone and unlocking the system for volume adjustment
EP0776247B1 (en) Pipette for distributing successive volumes of a liquid
CA2844778C (en) Positive-displacement pipette having an improved ejection function
EP3749454B1 (en) System for ejecting tips of sampling pipettes with improved ergonomics
FR2911530A1 (en) Manual fastener e.g. nail, driving apparatus, has fastener pushing device mounted on guide for pushing fasteners and controlled by driving pusher, where guide has supply opening in zone of housing for supplying fasteners
FR2475688A1 (en) DEVICE FOR ERASING (OR REMOVING) ARMS FROM INSERTION MACHINES
FR2807340A1 (en) LIQUID SAMPLING PIPETTE WITH CONE EJECTOR MECHANISM
WO2005015031A1 (en) Remote controller for heavy construction machines with pushrod follower
FR2844333A1 (en) Quick coupling system for car brake fluid tank comprises sockets mounted on movable plate, into which pipes fit, lever attached to plate allowing coupling to be released
FR2770436A1 (en) SEALING TOOL
EP3200923B1 (en) Hand-held pipette with ergonomic actuator
EP1906034A2 (en) Ball-and-socket joint device between a lever and a drive shaft
FR2861330A1 (en) Writing instrument e.g. mechanical pencil, has writing point forwarding mechanism with movable part having bearing that supports cam during tilting movement of side button
EP0546927B1 (en) Hand brake lever for a parking brake
EP0333525A1 (en) Connection between an actuating pedal and a translatory mobile controlling member
FR2499920A1 (en) Vehicle windscreen-wiper arm - has leaf spring on hinge to bias blade onto windscreen
FR2820669A1 (en) HOLDER PISTON
EP0349368B1 (en) Adjustable disc brake
EP0501883B1 (en) Screwdriver with flat blade and retractable guiding device
CH624312A5 (en) Micropipette with ejectable tip
FR2705079A1 (en) Operating device for cycle derailleur and brake
EP0046830A1 (en) Precision compass with articulated legs and rigid cross-bar
FR3128889A1 (en) POSITIVE DISPLACEMENT SAMPLING DEVICE, DESIGNED TO IMPROVE THE GRIP OF THE PISTON OF A PISTON-CAPILLARY SYSTEM
FR2847356A1 (en) Accelerator pedal for motor vehicle has movable arm mounted for pivoting on support frame and with retractable stop to limit vehicle speed
FR2604698A1 (en) Portable electric can opener

Legal Events

Date Code Title Description
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: UNKNOWN

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE

PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE

17P Request for examination filed

Effective date: 20200910

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

AX Request for extension of the european patent

Extension state: BA ME

GRAJ Information related to disapproval of communication of intention to grant by the applicant or resumption of examination proceedings by the epo deleted

Free format text: ORIGINAL CODE: EPIDOSDIGR1

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: GRANT OF PATENT IS INTENDED

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

DAV Request for validation of the european patent (deleted)
DAX Request for extension of the european patent (deleted)
INTG Intention to grant announced

Effective date: 20210607

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE PATENT HAS BEEN GRANTED

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

REG Reference to a national code

Ref country code: GB

Ref legal event code: FG4D

Free format text: NOT ENGLISH

REG Reference to a national code

Ref country code: AT

Ref legal event code: REF

Ref document number: 1445569

Country of ref document: AT

Kind code of ref document: T

Effective date: 20211115

Ref country code: CH

Ref legal event code: EP

REG Reference to a national code

Ref country code: DE

Ref legal event code: R096

Ref document number: 602019009206

Country of ref document: DE

REG Reference to a national code

Ref country code: IE

Ref legal event code: FG4D

Free format text: LANGUAGE OF EP DOCUMENT: FRENCH

REG Reference to a national code

Ref country code: FI

Ref legal event code: FGE

REG Reference to a national code

Ref country code: LT

Ref legal event code: MG9D

REG Reference to a national code

Ref country code: NL

Ref legal event code: MP

Effective date: 20211110

REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2905730

Country of ref document: ES

Kind code of ref document: T3

Effective date: 20220411

REG Reference to a national code

Ref country code: AT

Ref legal event code: MK05

Ref document number: 1445569

Country of ref document: AT

Kind code of ref document: T

Effective date: 20211110

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: RS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: LT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: BG

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220210

Ref country code: AT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IS

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220310

Ref country code: SE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: PT

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220310

Ref country code: NO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220210

Ref country code: NL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: LV

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: HR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: GR

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20220211

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SM

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: SK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: RO

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: EE

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: DK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: CZ

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: IT

Payment date: 20220531

Year of fee payment: 4

REG Reference to a national code

Ref country code: DE

Ref legal event code: R097

Ref document number: 602019009206

Country of ref document: DE

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20220811

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AL

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: ES

Payment date: 20220929

Year of fee payment: 4

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SI

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

REG Reference to a national code

Ref country code: BE

Ref legal event code: MM

Effective date: 20220531

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MC

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220503

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: IE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220503

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20220531

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20230526

Year of fee payment: 5

Ref country code: DE

Payment date: 20230519

Year of fee payment: 5

Ref country code: CH

Payment date: 20230602

Year of fee payment: 5

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: PL

Payment date: 20230424

Year of fee payment: 5

Ref country code: FI

Payment date: 20230523

Year of fee payment: 5

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20230524

Year of fee payment: 5

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: MK

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110

Ref country code: IT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20230503

Ref country code: CY

Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT

Effective date: 20211110