EP3737738A4 - Akustische verarbeitung für zell- und gentherapie - Google Patents

Akustische verarbeitung für zell- und gentherapie Download PDF

Info

Publication number
EP3737738A4
EP3737738A4 EP19738317.7A EP19738317A EP3737738A4 EP 3737738 A4 EP3737738 A4 EP 3737738A4 EP 19738317 A EP19738317 A EP 19738317A EP 3737738 A4 EP3737738 A4 EP 3737738A4
Authority
EP
European Patent Office
Prior art keywords
cell
gene therapy
acoustic processing
acoustic
processing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP19738317.7A
Other languages
English (en)
French (fr)
Other versions
EP3737738A1 (de
Inventor
Bart Lipkens
Rui TOSTOES
Jr. Walter M. Presz
Benjamin Ross-Johnsrud
Kedar CHITALE
Iii Thomas J. Kennedy
Brian DUTRA
Brian Mccarthy
Jack Saloio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Flodesign Sonics Inc
Original Assignee
Flodesign Sonics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/916,270 external-priority patent/US11377651B2/en
Priority claimed from US15/942,427 external-priority patent/US11085035B2/en
Priority claimed from US15/942,316 external-priority patent/US11021699B2/en
Priority claimed from US15/963,809 external-priority patent/US11474085B2/en
Priority claimed from US15/983,823 external-priority patent/US11459540B2/en
Priority claimed from US16/010,296 external-priority patent/US20180362918A1/en
Priority claimed from US16/124,184 external-priority patent/US11214789B2/en
Application filed by Flodesign Sonics Inc filed Critical Flodesign Sonics Inc
Publication of EP3737738A1 publication Critical patent/EP3737738A1/de
Publication of EP3737738A4 publication Critical patent/EP3737738A4/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/28—Mechanical auxiliary equipment for acceleration of sedimentation, e.g. by vibrators or the like
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/22—Settling tanks; Sedimentation by gravity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1807—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP19738317.7A 2018-01-09 2019-01-09 Akustische verarbeitung für zell- und gentherapie Pending EP3737738A4 (de)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201862615420P 2018-01-09 2018-01-09
US201862617074P 2018-01-12 2018-01-12
US15/916,270 US11377651B2 (en) 2016-10-19 2018-03-08 Cell therapy processes utilizing acoustophoresis
US15/942,427 US11085035B2 (en) 2016-05-03 2018-03-30 Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
US15/942,316 US11021699B2 (en) 2015-04-29 2018-03-30 Separation using angled acoustic waves
US15/963,809 US11474085B2 (en) 2015-07-28 2018-04-26 Expanded bed affinity selection
US201862668777P 2018-05-08 2018-05-08
US15/983,823 US11459540B2 (en) 2015-07-28 2018-05-18 Expanded bed affinity selection
US16/010,296 US20180362918A1 (en) 2016-05-03 2018-06-15 Cell Therapy Processes Utilizing Acoustophoresis
US16/124,184 US11214789B2 (en) 2016-05-03 2018-09-06 Concentration and washing of particles with acoustics
PCT/US2019/012950 WO2019140019A1 (en) 2018-01-09 2019-01-09 Acoustic processing for cell and gene therapy

Publications (2)

Publication Number Publication Date
EP3737738A1 EP3737738A1 (de) 2020-11-18
EP3737738A4 true EP3737738A4 (de) 2021-05-05

Family

ID=67219903

Family Applications (1)

Application Number Title Priority Date Filing Date
EP19738317.7A Pending EP3737738A4 (de) 2018-01-09 2019-01-09 Akustische verarbeitung für zell- und gentherapie

Country Status (3)

Country Link
EP (1) EP3737738A4 (de)
CN (1) CN111630146A (de)
WO (1) WO2019140019A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
CN115066489A (zh) * 2020-01-17 2022-09-16 弗洛设计声能学公司 使用晶种粒子的增强声学粒子处理
EP4144826A1 (de) 2021-09-06 2023-03-08 Kolibri Zellkultursystem mit fächern und einer akustischen betätigungsvorrichtung und verfahren dafür

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130309757A1 (en) * 2010-12-17 2013-11-21 Sung-Chun Kim Method and apparatus for producing cells and fat soluble materials by cell culture
US20170137774A1 (en) * 2012-03-15 2017-05-18 Flodesign Sonics, Inc. Acoustic perfusion devices
WO2017192760A1 (en) * 2016-05-03 2017-11-09 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100006501A1 (en) * 2006-05-05 2010-01-14 Erysave Ab Method for separation
US9688958B2 (en) * 2012-03-15 2017-06-27 Flodesign Sonics, Inc. Acoustic bioreactor processes
US20150253226A1 (en) * 2012-09-21 2015-09-10 Acousort Ab Method for separating cells-bead complexes
DE102014005451A1 (de) 2014-04-07 2015-10-08 Adam Krecisz Saatgutgranulat und Verfahren sowie Vorrichtung zu dessen Herstellung
CN107921332A (zh) * 2015-04-29 2018-04-17 弗洛设计超声波公司 用于倾斜波颗粒偏转的声泳装置
US9663756B1 (en) * 2016-02-25 2017-05-30 Flodesign Sonics, Inc. Acoustic separation of cellular supporting materials from cultured cells

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130309757A1 (en) * 2010-12-17 2013-11-21 Sung-Chun Kim Method and apparatus for producing cells and fat soluble materials by cell culture
US20170137774A1 (en) * 2012-03-15 2017-05-18 Flodesign Sonics, Inc. Acoustic perfusion devices
WO2017192760A1 (en) * 2016-05-03 2017-11-09 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2019140019A1 *

Also Published As

Publication number Publication date
CN111630146A (zh) 2020-09-04
EP3737738A1 (de) 2020-11-18
WO2019140019A1 (en) 2019-07-18
WO2019140019A8 (en) 2020-08-27

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