EP3635119A4 - Zusammensetzungen und verfahren zur genomeditierung - Google Patents

Zusammensetzungen und verfahren zur genomeditierung Download PDF

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Publication number
EP3635119A4
EP3635119A4 EP18813973.7A EP18813973A EP3635119A4 EP 3635119 A4 EP3635119 A4 EP 3635119A4 EP 18813973 A EP18813973 A EP 18813973A EP 3635119 A4 EP3635119 A4 EP 3635119A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
genome editing
editing
genome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP18813973.7A
Other languages
English (en)
French (fr)
Other versions
EP3635119A2 (de
Inventor
John Lindbo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vilmorin SA
Original Assignee
Vilmorin SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vilmorin SA filed Critical Vilmorin SA
Publication of EP3635119A2 publication Critical patent/EP3635119A2/de
Publication of EP3635119A4 publication Critical patent/EP3635119A4/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
EP18813973.7A 2017-06-09 2018-06-07 Zusammensetzungen und verfahren zur genomeditierung Pending EP3635119A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762517360P 2017-06-09 2017-06-09
PCT/US2018/036480 WO2018226972A2 (en) 2017-06-09 2018-06-07 Compositions and methods for genome editing

Publications (2)

Publication Number Publication Date
EP3635119A2 EP3635119A2 (de) 2020-04-15
EP3635119A4 true EP3635119A4 (de) 2021-04-14

Family

ID=64566013

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18813973.7A Pending EP3635119A4 (de) 2017-06-09 2018-06-07 Zusammensetzungen und verfahren zur genomeditierung

Country Status (5)

Country Link
US (1) US11845942B2 (de)
EP (1) EP3635119A4 (de)
IL (1) IL271232A (de)
MA (1) MA52134A (de)
WO (1) WO2018226972A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA52134A (fr) 2017-06-09 2020-04-15 Vilmorin & Cie Compositions et procédés pour l'édition génomique
US20210238612A1 (en) 2018-07-12 2021-08-05 Keygene N.V. Type v crispr/nuclease-system for genome editing in plant cells
JP2022533589A (ja) * 2019-05-13 2022-07-25 イーエムディ・ミリポア・コーポレイション Ｃｒｉｓｐｒタンパク質をコードする合成自己複製ｒｎａベクターおよびその使用
EP3973062A1 (de) * 2019-05-23 2022-03-30 Nomad Bioscience GmbH Rna-virales rna-molekül zum gen-editing
EP3987039A1 (de) * 2019-06-19 2022-04-27 Betterseeds Ltd. Verfahren zur erhöhung der cannabisausbeute durch geneditierung
EP4063500A4 (de) * 2019-11-18 2023-12-27 Suzhou Qi Biodesign biotechnology Company Limited Aus flavobakterien stammendes geneditierungssystem
US20230357796A1 (en) * 2019-11-27 2023-11-09 Danmarks Tekniske Universitet Constructs, compositions and methods thereof having improved genome editing efficiency and specificity
CN115552001A (zh) * 2020-05-15 2022-12-30 孟山都技术公司 用于检测基因组编辑的系统和方法
CN112626275A (zh) * 2021-01-14 2021-04-09 北京市农林科学院 基于一步法rt-pcr技术检测或辅助检测南方番茄病毒的引物对和方法
CN113355337B (zh) * 2021-04-14 2023-06-20 河南农业大学 一种创制地黄杂合突变体的方法及应用
JP2024513588A (ja) 2021-04-15 2024-03-26 キージーン ナムローゼ フェンノートシャップ 遺伝性突然変異のための可動性エンドヌクレアーゼ
IL305936A (en) 2021-04-15 2023-11-01 Keygene Nv Integrated regeneration of recalcitrant plants
MX2024005239A (es) * 2021-11-01 2024-07-22 Flagship Pioneering Innovations Vii Llc Polinucleotidos para modificar organismos.
WO2023111225A1 (en) 2021-12-17 2023-06-22 Keygene N.V. Double decapitation of plants
WO2024133851A1 (en) 2022-12-22 2024-06-27 Keygene N.V. Regeneration by protoplast callus grafting

Family Cites Families (15)

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US5316931A (en) 1988-02-26 1994-05-31 Biosource Genetics Corp. Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes
US5959185A (en) 1998-02-13 1999-09-28 Pioneer Hi-Bred International, Inc. Soybean variety 95B41
US5973234A (en) 1998-02-13 1999-10-26 Pioneer Hi-Bred International, Inc. Soybean variety 95B33
US5977445A (en) 1998-06-30 1999-11-02 Pioneer Hi-Bred International, Inc. Soybean variety 91B64
IL150439A0 (en) * 2000-01-04 2002-12-01 Ruiter Seeds C V Lp De Cultivated tomato plant having increased brix value and method of producing same
US8936937B2 (en) 2007-01-29 2015-01-20 The Ohio State University Research Foundation System for expression of genes in plants from a virus-based expression vector
FR2925918A1 (fr) 2007-12-28 2009-07-03 Pasteur Institut Typage et sous-typage moleculaire de salmonella par identification des sequences nucleotidiques variables des loci crispr
US9102936B2 (en) 2012-06-11 2015-08-11 Agilent Technologies, Inc. Method of adaptor-dimer subtraction using a CRISPR CAS6 protein
US20140310830A1 (en) 2012-12-12 2014-10-16 Feng Zhang CRISPR-Cas Nickase Systems, Methods And Compositions For Sequence Manipulation in Eukaryotes
US8697359B1 (en) 2012-12-12 2014-04-15 The Broad Institute, Inc. CRISPR-Cas systems and methods for altering expression of gene products
EP3825401A1 (de) 2012-12-12 2021-05-26 The Broad Institute, Inc. Systeme, verfahren und zusammensetzungen mit crispr-cas-komponenten zur sequenzmanipulation
AU2014227831B2 (en) 2013-03-15 2020-01-30 Regents Of The University Of Minnesota Engineering plant genomes using CRISPR/Cas systems
WO2015189693A1 (en) 2014-06-12 2015-12-17 King Abdullah University Of Science And Technology Targeted viral-mediated plant genome editing using crispr/cas9
EP3230452A1 (de) * 2014-12-12 2017-10-18 The Broad Institute Inc. Totführungen für crispr-transkriptionsfaktoren
MA52134A (fr) 2017-06-09 2020-04-15 Vilmorin & Cie Compositions et procédés pour l'édition génomique

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
LE CONG ET AL: "Multiplex Genome Engineering Using CRISPR/Cas Systems", SCIENCE, vol. 339, no. 6121, 14 February 2013 (2013-02-14), US, pages 819 - 823, XP055458249, ISSN: 0036-8075, DOI: 10.1126/science.1231143 *
PRASHANT MALI ET AL: "CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering", NATURE BIOTECHNOLOGY, vol. 31, no. 9, 1 September 2013 (2013-09-01), us, pages 833 - 838, XP055693154, ISSN: 1087-0156, DOI: 10.1038/nbt.2675 *
SEUNG WOO CHO ET AL: "Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease (includes Supplementary information)", NATURE BIOTECHNOLOGY, GALE GROUP INC., NEW YORK, US, vol. 31, no. 3, 1 March 2013 (2013-03-01), pages 230 - 232, 1, XP002699850, ISSN: 1087-0156, [retrieved on 20130129], DOI: 10.1038/NBT.2507 *

Also Published As

Publication number Publication date
EP3635119A2 (de) 2020-04-15
WO2018226972A2 (en) 2018-12-13
US20200199605A1 (en) 2020-06-25
MA52134A (fr) 2020-04-15
IL271232A (en) 2020-01-30
US11845942B2 (en) 2023-12-19
WO2018226972A3 (en) 2020-02-20

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