EP3630944A4 - Verfahren zur herstellung bakterieller zusammensetzungen mit einem biofilm mit nützlichen bakterien - Google Patents

Verfahren zur herstellung bakterieller zusammensetzungen mit einem biofilm mit nützlichen bakterien Download PDF

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Publication number
EP3630944A4
EP3630944A4 EP18810460.8A EP18810460A EP3630944A4 EP 3630944 A4 EP3630944 A4 EP 3630944A4 EP 18810460 A EP18810460 A EP 18810460A EP 3630944 A4 EP3630944 A4 EP 3630944A4
Authority
EP
European Patent Office
Prior art keywords
benefecial
biofilm
bacteria
bacterial compositions
generation bacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18810460.8A
Other languages
English (en)
French (fr)
Other versions
EP3630944A1 (de
Inventor
Moshe Shemesh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Israel Ministry of Agriculture and Rural Development
Agricultural Research Organization of Israel Ministry of Agriculture
Original Assignee
Israel Ministry of Agriculture and Rural Development
Agricultural Research Organization of Israel Ministry of Agriculture
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IL2017/050603 external-priority patent/WO2017208237A1/en
Application filed by Israel Ministry of Agriculture and Rural Development, Agricultural Research Organization of Israel Ministry of Agriculture filed Critical Israel Ministry of Agriculture and Rural Development
Publication of EP3630944A1 publication Critical patent/EP3630944A1/de
Publication of EP3630944A4 publication Critical patent/EP3630944A4/de
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/742Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04Preserving or maintaining viable microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07Bacillus
    • C12R2001/125Bacillus subtilis ; Hay bacillus; Grass bacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225Lactobacillus
    • C12R2001/25Lactobacillus plantarum

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Fodder In General (AREA)
EP18810460.8A 2017-05-29 2018-05-29 Verfahren zur herstellung bakterieller zusammensetzungen mit einem biofilm mit nützlichen bakterien Withdrawn EP3630944A4 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/IL2017/050603 WO2017208237A1 (en) 2016-05-29 2017-05-29 Method of generating bacterial compositions
US201762588365P 2017-11-19 2017-11-19
US201862644528P 2018-03-18 2018-03-18
PCT/IL2018/050588 WO2018220630A1 (en) 2017-05-29 2018-05-29 Method of generation bacterial compositions comprising a biofilm with benefecial bacteria

Publications (2)

Publication Number Publication Date
EP3630944A1 EP3630944A1 (de) 2020-04-08
EP3630944A4 true EP3630944A4 (de) 2021-03-31

Family

ID=64455982

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18810460.8A Withdrawn EP3630944A4 (de) 2017-05-29 2018-05-29 Verfahren zur herstellung bakterieller zusammensetzungen mit einem biofilm mit nützlichen bakterien

Country Status (6)

Country Link
EP (1) EP3630944A4 (de)
JP (1) JP7228533B2 (de)
CN (1) CN110945116A (de)
CA (1) CA3064942A1 (de)
IL (1) IL271044A (de)
WO (1) WO2018220630A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3462917A4 (de) 2016-05-29 2020-01-08 The State of Isreal, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) Verfahren zur erzeugung von bakteriellen zusammensetzungen
US20220184153A1 (en) * 2019-03-25 2022-06-16 The State of Israel, Ministry of Agriculture&Rural Development, Agricltural Research Oganization(ARO Method of treating bovine mastitis
CA3140280A1 (en) * 2019-05-29 2020-12-03 Chr. Hansen A/S Composition comprising biofilm forming bacillus
CN111254089B (zh) * 2019-12-30 2022-01-18 杭州娃哈哈科技有限公司 一株具有减肥功能的植物乳杆菌及其应用
CN112869171A (zh) * 2021-01-29 2021-06-01 陕西科技大学 一种益生菌膳食纤维粉及其制备方法
CN113083383B (zh) * 2021-03-18 2022-10-25 华中农业大学 微流控芯片装置、制备方法及土壤微生物群落培养方法
CN116555069B (zh) * 2022-12-27 2023-10-20 华北电力大学 一株具有耐盐好氧反硝化特性的柴油食烷菌

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016181228A2 (en) * 2015-05-11 2016-11-17 Mybiotix Pharma Ltd. Systems and methods for growing a biofilm of probiotic bacteria on solid particles for colonization of bacteria in the gut
WO2017203440A1 (en) * 2016-05-25 2017-11-30 Universita' Degli Studi Di Foggia Method for producing microbial probiotic biofilms and uses thereof
WO2017208237A1 (en) * 2016-05-29 2017-12-07 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Method of generating bacterial compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009017124A1 (ja) * 2007-07-31 2009-02-05 Nihon University バイオフィルムの生産方法
JP2010195711A (ja) * 2009-02-25 2010-09-09 Kao Corp バイオフィルム形成促進剤
CN103911323B (zh) * 2014-03-28 2016-06-29 内蒙古和美科盛生物技术有限公司 地衣芽孢杆菌、枯草芽孢杆菌和植物乳杆菌制剂及制备
US20170020178A1 (en) * 2015-03-25 2017-01-26 Functional Fungi, Llc Nutritionally and Botanically Enhanced Microbial/Bacterial Biomass

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016181228A2 (en) * 2015-05-11 2016-11-17 Mybiotix Pharma Ltd. Systems and methods for growing a biofilm of probiotic bacteria on solid particles for colonization of bacteria in the gut
WO2017203440A1 (en) * 2016-05-25 2017-11-30 Universita' Degli Studi Di Foggia Method for producing microbial probiotic biofilms and uses thereof
WO2017208237A1 (en) * 2016-05-29 2017-12-07 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Method of generating bacterial compositions

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
CALASSO M. ET AL: "Effects of the Peptide Pheromone Plantaricin A and Cocultivation with Lactobacillus sanfranciscensis DPPMA174 on the Exoproteome and the Adhesion Capacity of Lactobacillus plantarum DC400", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 79, no. 8, 15 April 2013 (2013-04-15), US, pages 2657 - 2669, XP055769378, ISSN: 0099-2240, DOI: 10.1128/AEM.03625-12 *
CHEOW W. S. ET AL: "Biofilm-Like Lactobacillus rhamnosus Probiotics Encapsulated in Alginate and Carrageenan Microcapsules Exhibiting Enhanced Thermotolerance and Freeze-Drying Resistance", BIOMACROMOLECULES, vol. 14, no. 9, 9 September 2013 (2013-09-09), US, pages 3214 - 3222, XP055422567, ISSN: 1525-7797, DOI: 10.1021/bm400853d *
LEBEER S. ET AL: "Impact of Environmental and Genetic Factors on Biofilm Formation by the Probiotic Strain Lactobacillus rhamnosus GG", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 73, no. 21, 1 November 2007 (2007-11-01), US, pages 6768 - 6775, XP055432832, ISSN: 0099-2240, DOI: 10.1128/AEM.01393-07 *
See also references of WO2018220630A1 *
VAN DER VEEN S. ET AL: "Mixed species biofilms of Listeria monocytogenes and Lactobacillus plantarum show enhanced resistance to benzalkonium chloride and peracetic acid", INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, vol. 144, no. 3, 5 January 2011 (2011-01-05), pages 421 - 431, XP027557687, ISSN: 0168-1605, [retrieved on 20101029] *
YAHAV S. ET AL: "Encapsulation of beneficial probiotic bacteria in extracellular matrix from biofilm-forming Bacillus subtilis", ARTIFICIAL CELLS, NANOMEDICINE AND BIOTECHNOLOGY, vol. 46, no. sup2, 27 May 2018 (2018-05-27), US, pages 974 - 982, XP055769472, ISSN: 2169-1401, DOI: 10.1080/21691401.2018.1476373 *

Also Published As

Publication number Publication date
EP3630944A1 (de) 2020-04-08
CA3064942A1 (en) 2018-12-06
IL271044A (en) 2020-01-30
JP2020528264A (ja) 2020-09-24
JP7228533B2 (ja) 2023-02-24
WO2018220630A1 (en) 2018-12-06
CN110945116A (zh) 2020-03-31

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