EP3614912A4 - SYSTEMS, DEVICES AND METHODS FOR APPLYING PULSED ELECTRIC FIELD ABLATION ENERGY TO ENDOCARDE TISSUE - Google Patents

SYSTEMS, DEVICES AND METHODS FOR APPLYING PULSED ELECTRIC FIELD ABLATION ENERGY TO ENDOCARDE TISSUE Download PDF

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Publication number
EP3614912A4
EP3614912A4 EP18790020.4A EP18790020A EP3614912A4 EP 3614912 A4 EP3614912 A4 EP 3614912A4 EP 18790020 A EP18790020 A EP 18790020A EP 3614912 A4 EP3614912 A4 EP 3614912A4
Authority
EP
European Patent Office
Prior art keywords
systems
methods
devices
electric field
ablation energy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP18790020.4A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3614912A1 (en
Inventor
Raju Viswanathan
Allan Zingeler
Gary Long
Jean-Luc Pageard
Brittney HACHEY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Scientific Scimed Inc
Original Assignee
Farapulse Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/711,266 external-priority patent/US10172673B2/en
Priority claimed from US15/874,721 external-priority patent/US10130423B1/en
Application filed by Farapulse Inc filed Critical Farapulse Inc
Priority claimed from PCT/US2018/029938 external-priority patent/WO2018201037A1/en
Publication of EP3614912A1 publication Critical patent/EP3614912A1/en
Publication of EP3614912A4 publication Critical patent/EP3614912A4/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206—Generators therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25—Bioelectric electrodes therefor
    • A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
    • A61B5/283—Invasive
    • A61B5/287—Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/321—Accessories or supplementary instruments therefor, e.g. cord hangers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/333—Recording apparatus specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/056—Transvascular endocardial electrode systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00059—Material properties
    • A61B2018/00071—Electrical conductivity
    • A61B2018/00083—Electrical conductivity low, i.e. electrically insulating
    • A—HUMAN NECESSITIES
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    • A61B2018/0016—Energy applicators arranged in a two- or three dimensional array
    • A—HUMAN NECESSITIES
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    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
    • A61B2018/0022—Balloons
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    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
    • A61B2018/00267—Expandable means emitting energy, e.g. by elements carried thereon having a basket shaped structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A61B2018/00351—Heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A61B2018/00351—Heart
    • A61B2018/00357—Endocardium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A61B2018/00351—Heart
    • A61B2018/00375—Ostium, e.g. ostium of pulmonary vein or artery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00613—Irreversible electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00839—Bioelectrical parameters, e.g. ECG, EEG
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206—Generators therefor
    • A61B2018/1246—Generators therefor characterised by the output polarity
    • A61B2018/126—Generators therefor characterised by the output polarity bipolar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1407—Loop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1435—Spiral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Vascular Medicine (AREA)
  • Physiology (AREA)
  • Surgical Instruments (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
EP18790020.4A 2017-04-28 2018-04-27 SYSTEMS, DEVICES AND METHODS FOR APPLYING PULSED ELECTRIC FIELD ABLATION ENERGY TO ENDOCARDE TISSUE Pending EP3614912A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762491910P 2017-04-28 2017-04-28
US201762529268P 2017-07-06 2017-07-06
US15/711,266 US10172673B2 (en) 2016-01-05 2017-09-21 Systems devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
US15/874,721 US10130423B1 (en) 2017-07-06 2018-01-18 Systems, devices, and methods for focal ablation
PCT/US2018/029938 WO2018201037A1 (en) 2017-04-28 2018-04-27 Systems, devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue

Publications (2)

Publication Number Publication Date
EP3614912A1 EP3614912A1 (en) 2020-03-04
EP3614912A4 true EP3614912A4 (en) 2021-03-03

Family

ID=69036368

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18790020.4A Pending EP3614912A4 (en) 2017-04-28 2018-04-27 SYSTEMS, DEVICES AND METHODS FOR APPLYING PULSED ELECTRIC FIELD ABLATION ENERGY TO ENDOCARDE TISSUE

Country Status (3)

Country Link
EP (1) EP3614912A4 (https=)
JP (3) JP2020517355A (https=)
CN (4) CN119732732A (https=)

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WO2019195439A1 (en) 2018-04-05 2019-10-10 St. Jude Medical, Cardiology Division, Inc. High density electrode mapping catheter
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CN111728693A (zh) * 2020-07-06 2020-10-02 白龙腾 一种采用脉冲电场消融技术治疗心律失常的系统
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US20220047326A1 (en) * 2020-08-13 2022-02-17 Biosense Webster (Israel) Ltd. Applying Bipolar Ablation Energy Between Shorted Electrode Groups
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US20220257297A1 (en) * 2021-02-12 2022-08-18 Boston Scientific Scimed Inc Pulse sequence for cardiac ablation by irreversible electroporation with low skeletal muscle stimulation
JP7595739B2 (ja) * 2021-02-22 2024-12-06 日本ライフライン株式会社 電源装置およびアブレーションシステム
JPWO2022176203A1 (https=) * 2021-02-22 2022-08-25
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CN113100919B (zh) * 2021-04-23 2025-05-27 上海安钛克医疗科技有限公司 电极、电生理导管及消融系统
CA3215962A1 (en) * 2021-04-26 2022-11-03 Roman Turovskiy Circumferential ablation devices and methods
CN113243987A (zh) * 2021-04-30 2021-08-13 上海鑫律通生命科技有限公司 一种采用组合电极的消融导管系统
CN113274124B (zh) * 2021-06-22 2025-05-27 上海安钛克医疗科技有限公司 电极组件、电生理导管及电生理系统
US12453597B2 (en) * 2021-07-02 2025-10-28 Boston Scientific Scimed, Inc. Focal ablation devices with foldable elements, and systems and methods thereof
CN117999041A (zh) * 2021-07-27 2024-05-07 波士顿科学医学有限公司 具有多状态的电穿孔导管的电场可视化
US12004804B2 (en) 2021-09-09 2024-06-11 Biosense Webster (Israel) Ltd. Basket catheter with mushroom shape distal tip
CN118076308A (zh) * 2021-10-04 2024-05-24 波士顿科学医学有限公司 具有集成导航传感器的心脏消融导管
CN114081616A (zh) * 2021-11-23 2022-02-25 四川锦江电子科技有限公司 一种多电极臂消融导管
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CN114767256A (zh) * 2022-01-27 2022-07-22 苏州心岭迈德医疗科技有限公司 一种电极间距变化的消融导管及设备
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CN115177363A (zh) * 2022-05-17 2022-10-14 上海玮启医疗器械有限公司 脉冲消融导管
CN115105188B (zh) * 2022-06-23 2024-11-12 上海诺生医疗科技有限公司 消融导管和消融装置
CN116098698A (zh) * 2022-06-24 2023-05-12 苏州浩微生物医疗科技有限公司 可调距柔性消融电极、消融系统及消融方法
CN120035406A (zh) * 2022-10-14 2025-05-23 脉冲生物科学有限公司 多撑条消融和感测导管装置及方法
CN116173376A (zh) * 2022-12-20 2023-05-30 杭州诺生医疗科技有限公司 导丝组件以及穿刺系统
US20240398469A1 (en) * 2023-06-05 2024-12-05 Biosense Webster (Israel) Ltd. Expandable basket assemblies and expandable basket assemblies with electrode wire strain relief
CN116919562B (zh) * 2023-08-08 2024-08-13 融和医疗科技(浙江)有限公司 一种口腔消融装置
JP2025050036A (ja) * 2023-09-22 2025-04-04 日本ライフライン株式会社 電源装置およびアブレーションシステム
JP2025087275A (ja) * 2023-11-29 2025-06-10 日本ライフライン株式会社 電極カテーテル

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EP3614912A1 (en) 2020-03-04
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