EP3609329A4 - Compositions, produits pharmaceutiques conditionnés, et méthodes d'utilisation de posaconazole pour la sensibilisation de tumeurs résistantes - Google Patents
Compositions, produits pharmaceutiques conditionnés, et méthodes d'utilisation de posaconazole pour la sensibilisation de tumeurs résistantes Download PDFInfo
- Publication number
- EP3609329A4 EP3609329A4 EP18783809.9A EP18783809A EP3609329A4 EP 3609329 A4 EP3609329 A4 EP 3609329A4 EP 18783809 A EP18783809 A EP 18783809A EP 3609329 A4 EP3609329 A4 EP 3609329A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- posaconazole
- sensitization
- compositions
- methods
- resistant tumors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 206010070834 Sensitisation Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- RAGOYPUPXAKGKH-XAKZXMRKSA-N posaconazole Chemical compound O=C1N([C@H]([C@H](C)O)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@H]3C[C@@](CN4N=CN=C4)(OC3)C=3C(=CC(F)=CC=3)F)=CC=2)C=C1 RAGOYPUPXAKGKH-XAKZXMRKSA-N 0.000 title 1
- 229960001589 posaconazole Drugs 0.000 title 1
- 230000008313 sensitization Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762484852P | 2017-04-12 | 2017-04-12 | |
PCT/US2018/027371 WO2018191541A1 (fr) | 2017-04-12 | 2018-04-12 | Compositions, produits pharmaceutiques conditionnés, et méthodes d'utilisation de posaconazole pour la sensibilisation de tumeurs résistantes |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3609329A1 EP3609329A1 (fr) | 2020-02-19 |
EP3609329A4 true EP3609329A4 (fr) | 2021-03-17 |
Family
ID=63793667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP18783809.9A Withdrawn EP3609329A4 (fr) | 2017-04-12 | 2018-04-12 | Compositions, produits pharmaceutiques conditionnés, et méthodes d'utilisation de posaconazole pour la sensibilisation de tumeurs résistantes |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP3609329A4 (fr) |
KR (1) | KR20200059188A (fr) |
CN (1) | CN111093373A (fr) |
AU (1) | AU2018253189A1 (fr) |
CA (1) | CA3063115A1 (fr) |
WO (1) | WO2018191541A1 (fr) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013037043A1 (fr) * | 2011-09-13 | 2013-03-21 | Universite De Montreal | Combinaison thérapeutique utilisant la ribavirine en tant qu'inhibiteur d'elf4e |
US20140315920A1 (en) * | 2013-04-17 | 2014-10-23 | Hedgepath, Llc. | Treatment and prognostic monitoring of proliferation disorders using hedgehog pathway inhibitors |
WO2016011328A1 (fr) * | 2014-07-17 | 2016-01-21 | Baker Cheryl | Traitement du cancer associant un rayonnement, des nanoparticules d'oxyde de cérium et un agent chimiothérapeutique |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005249502A1 (en) * | 2004-05-28 | 2005-12-15 | Schering Corporation | Particulate-stabilized injectable pharmaceutical compositions of posaconazole |
JP2008514726A (ja) * | 2004-09-30 | 2008-05-08 | ザ ユニヴァーシティー オヴ シカゴ | ヘッジホッグ阻害剤、放射線及び化学療法薬の併用療法 |
US8293754B2 (en) * | 2005-06-14 | 2012-10-23 | Aska Pharmaceutical Co., Ltd. | Thienopyrimidine derivatives |
JP5435946B2 (ja) * | 2005-08-22 | 2014-03-05 | ジョンズ ホプキンス ユニバーシティ | 疾患を処置するためのヘッジホッグ経路アンタゴニスト |
JP5205034B2 (ja) * | 2007-11-06 | 2013-06-05 | ローム株式会社 | 面発光レーザダイオード |
WO2012006584A2 (fr) * | 2010-07-08 | 2012-01-12 | Infinity Pharmaceuticals, Inc. | Régimes thérapeutiques pour les cancers associés à la voie de signalisation hedgehog |
-
2018
- 2018-04-12 CN CN201880038812.1A patent/CN111093373A/zh active Pending
- 2018-04-12 CA CA3063115A patent/CA3063115A1/fr not_active Abandoned
- 2018-04-12 KR KR1020197033474A patent/KR20200059188A/ko not_active Application Discontinuation
- 2018-04-12 EP EP18783809.9A patent/EP3609329A4/fr not_active Withdrawn
- 2018-04-12 AU AU2018253189A patent/AU2018253189A1/en not_active Abandoned
- 2018-04-12 WO PCT/US2018/027371 patent/WO2018191541A1/fr unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013037043A1 (fr) * | 2011-09-13 | 2013-03-21 | Universite De Montreal | Combinaison thérapeutique utilisant la ribavirine en tant qu'inhibiteur d'elf4e |
US20140315920A1 (en) * | 2013-04-17 | 2014-10-23 | Hedgepath, Llc. | Treatment and prognostic monitoring of proliferation disorders using hedgehog pathway inhibitors |
WO2016011328A1 (fr) * | 2014-07-17 | 2016-01-21 | Baker Cheryl | Traitement du cancer associant un rayonnement, des nanoparticules d'oxyde de cérium et un agent chimiothérapeutique |
Non-Patent Citations (1)
Title |
---|
See also references of WO2018191541A1 * |
Also Published As
Publication number | Publication date |
---|---|
AU2018253189A1 (en) | 2019-12-05 |
WO2018191541A1 (fr) | 2018-10-18 |
CA3063115A1 (fr) | 2018-10-18 |
EP3609329A1 (fr) | 2020-02-19 |
KR20200059188A (ko) | 2020-05-28 |
CN111093373A (zh) | 2020-05-01 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 45/06 20060101ALI20210205BHEP Ipc: A61K 31/475 20060101ALI20210205BHEP Ipc: A61P 35/00 20060101ALI20210205BHEP Ipc: A01N 43/48 20060101AFI20210205BHEP Ipc: A61K 31/496 20060101ALI20210205BHEP Ipc: A61K 31/337 20060101ALI20210205BHEP |
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18D | Application deemed to be withdrawn |
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