EP3582801A4 - Hilfsstoffverbindungen zur proteinverarbeitung - Google Patents

Hilfsstoffverbindungen zur proteinverarbeitung Download PDF

Info

Publication number
EP3582801A4
EP3582801A4 EP18754459.8A EP18754459A EP3582801A4 EP 3582801 A4 EP3582801 A4 EP 3582801A4 EP 18754459 A EP18754459 A EP 18754459A EP 3582801 A4 EP3582801 A4 EP 3582801A4
Authority
EP
European Patent Office
Prior art keywords
protein processing
additive compounds
additive
compounds
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP18754459.8A
Other languages
English (en)
French (fr)
Other versions
EP3582801A1 (de
Inventor
David S. Soane
Philip Wuthrich
Robert P. Mahoney
Mark Moody
Daniel G. GREENE
Neil L. Schauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Comera Life Sciences Inc
Original Assignee
Reform Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reform Biologics Inc filed Critical Reform Biologics Inc
Publication of EP3582801A1 publication Critical patent/EP3582801A1/de
Publication of EP3582801A4 publication Critical patent/EP3582801A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Water Supply & Treatment (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
EP18754459.8A 2017-02-16 2018-02-14 Hilfsstoffverbindungen zur proteinverarbeitung Withdrawn EP3582801A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762459893P 2017-02-16 2017-02-16
PCT/US2018/018123 WO2018152165A1 (en) 2017-02-16 2018-02-14 Excipient compounds for protein processing

Publications (2)

Publication Number Publication Date
EP3582801A1 EP3582801A1 (de) 2019-12-25
EP3582801A4 true EP3582801A4 (de) 2020-12-23

Family

ID=63170449

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18754459.8A Withdrawn EP3582801A4 (de) 2017-02-16 2018-02-14 Hilfsstoffverbindungen zur proteinverarbeitung

Country Status (5)

Country Link
EP (1) EP3582801A4 (de)
JP (1) JP2020507593A (de)
KR (1) KR102572453B1 (de)
CA (1) CA3053909A1 (de)
WO (1) WO2018152165A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10478498B2 (en) 2014-06-20 2019-11-19 Reform Biologics, Llc Excipient compounds for biopolymer formulations
WO2020112855A1 (en) * 2018-11-29 2020-06-04 Reform Biologics, Llc Excipient compounds for protein processing
WO2015196091A1 (en) 2014-06-20 2015-12-23 Reform Biologics, Llc Viscosity-reducing excipient compounds for protein formulations
KR20230018549A (ko) * 2018-03-07 2023-02-07 코메라 라이프 사이언시스, 인코포레이티드 단백질 제형을 위한 부형제 화합물
TWI871300B (zh) * 2019-01-28 2025-02-01 美商安進公司 藉由將藥物物質和藥物產品過程整體化的生物製劑製造之連續製造過程
US20220348608A1 (en) * 2019-10-04 2022-11-03 Merck Patent Gmbh Purification of proteins and viral inactivation
CN113621360A (zh) * 2020-05-06 2021-11-09 中国石油化工股份有限公司 一种稠油降粘剂及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5710311B2 (ja) * 2011-02-18 2015-04-30 株式会社日立製作所 添加培地の添加制御方法、及び当該方法を用いた細胞培養装置
EP3578203A1 (de) * 2011-10-28 2019-12-11 Integritybio Inc. Proteinformulierungen mit aminosäuren
EP2682168A1 (de) * 2012-07-02 2014-01-08 Millipore Corporation Reinigung biologischer Moleküle
IL312865B2 (en) * 2013-09-11 2025-06-01 Eagle Biologics Inc Liquid protein formulations containing viscosity-lowering agents
WO2015196091A1 (en) * 2014-06-20 2015-12-23 Reform Biologics, Llc Viscosity-reducing excipient compounds for protein formulations
SG11201702614SA (en) * 2014-10-01 2017-04-27 Eagle Biolog Inc Polysaccharide and nucleic acid formulations containing viscosity-lowering agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *

Also Published As

Publication number Publication date
CA3053909A1 (en) 2018-08-23
EP3582801A1 (de) 2019-12-25
WO2018152165A1 (en) 2018-08-23
JP2020507593A (ja) 2020-03-12
KR20190117631A (ko) 2019-10-16
KR102572453B1 (ko) 2023-08-29

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