EP3541801A4 - Procédés de préparation de 4-(6-(2-(2,4-difluorophényl)-1.1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile - Google Patents
Procédés de préparation de 4-(6-(2-(2,4-difluorophényl)-1.1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile Download PDFInfo
- Publication number
- EP3541801A4 EP3541801A4 EP17871908.4A EP17871908A EP3541801A4 EP 3541801 A4 EP3541801 A4 EP 3541801A4 EP 17871908 A EP17871908 A EP 17871908A EP 3541801 A4 EP3541801 A4 EP 3541801A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- difluorophenyl
- difluoro
- mercapto
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662423845P | 2016-11-18 | 2016-11-18 | |
PCT/US2017/062151 WO2018094140A1 (fr) | 2016-11-18 | 2017-11-17 | Procédés de préparation de 4-(6-(2-(2,4-difluorophényl)-1.1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3541801A1 EP3541801A1 (fr) | 2019-09-25 |
EP3541801A4 true EP3541801A4 (fr) | 2020-04-29 |
Family
ID=62146676
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP17871908.4A Withdrawn EP3541801A4 (fr) | 2016-11-18 | 2017-11-17 | Procédés de préparation de 4-(6-(2-(2,4-difluorophényl)-1.1-difluoro-2-hydroxy-3-(5-mercapto-1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile |
Country Status (5)
Country | Link |
---|---|
US (1) | US20190276429A1 (fr) |
EP (1) | EP3541801A4 (fr) |
CN (1) | CN109983004A (fr) |
BR (1) | BR112019009801A2 (fr) |
WO (1) | WO2018094140A1 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI636049B (zh) * | 2015-11-17 | 2018-09-21 | 美商維愛美製藥公司 | 製備4-((6-(2-(2,4-二氟苯基)-1,1-二氟-2-羥基-3-(1h-1,2,4-三唑-1-基)丙基)吡啶-3-基)氧基)苄腈之方法 |
WO2020020813A1 (fr) | 2018-07-25 | 2020-01-30 | Bayer Aktiengesellschaft | Combinaisons de composés actifs fongicides |
WO2020180832A1 (fr) * | 2019-03-06 | 2020-09-10 | Dow Agrosciences Llc | Composé difluoro-(2-hydroxypropyl)pyridine utilisé en tant que fongicide contre la sigatoka noire |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016187201A2 (fr) * | 2015-05-18 | 2016-11-24 | Viamet Pharmaceuticals, Inc. | Composés antifongiques |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105884743B (zh) * | 2011-06-19 | 2019-08-06 | 威尔金制药(Nc)有限公司 | 金属酶抑制剂化合物 |
US9447073B2 (en) * | 2013-05-28 | 2016-09-20 | Viamet Pharmaceuticals, Inc. | Fungicidal compositions |
HUE039015T2 (hu) * | 2013-06-12 | 2018-12-28 | Kaken Pharma Co Ltd | 4-Alkinil-imidazol-származék és ezt hatóanyagként tartalmazó gyógyszerkészítmény |
WO2015143188A1 (fr) * | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | 2-(2,4-difluorophényl)-1,1-difluoro-1-(pyridin-2-yl 5-substitué)-3-(1h-tétrazol-1-yl)propan-2-ols et procédés pour les préparer |
-
2017
- 2017-11-17 WO PCT/US2017/062151 patent/WO2018094140A1/fr unknown
- 2017-11-17 CN CN201780071195.0A patent/CN109983004A/zh active Pending
- 2017-11-17 BR BR112019009801A patent/BR112019009801A2/pt not_active Application Discontinuation
- 2017-11-17 EP EP17871908.4A patent/EP3541801A4/fr not_active Withdrawn
- 2017-11-17 US US16/462,183 patent/US20190276429A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016187201A2 (fr) * | 2015-05-18 | 2016-11-24 | Viamet Pharmaceuticals, Inc. | Composés antifongiques |
Non-Patent Citations (1)
Title |
---|
See also references of WO2018094140A1 * |
Also Published As
Publication number | Publication date |
---|---|
US20190276429A1 (en) | 2019-09-12 |
CN109983004A (zh) | 2019-07-05 |
BR112019009801A2 (pt) | 2019-08-06 |
EP3541801A1 (fr) | 2019-09-25 |
WO2018094140A1 (fr) | 2018-05-24 |
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A4 | Supplementary search report drawn up and despatched |
Effective date: 20200330 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/4196 20060101ALI20200324BHEP Ipc: C07D 401/06 20060101AFI20200324BHEP Ipc: A61K 31/4439 20060101ALI20200324BHEP |
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