EP3471885A1 - Kit de collecte d'échantillons et procédé de collecte d'échantillons de plante, en particulier d'échantillons d'algue - Google Patents

Kit de collecte d'échantillons et procédé de collecte d'échantillons de plante, en particulier d'échantillons d'algue

Info

Publication number
EP3471885A1
EP3471885A1 EP17726333.2A EP17726333A EP3471885A1 EP 3471885 A1 EP3471885 A1 EP 3471885A1 EP 17726333 A EP17726333 A EP 17726333A EP 3471885 A1 EP3471885 A1 EP 3471885A1
Authority
EP
European Patent Office
Prior art keywords
sample
tools
container
sample collection
processing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP17726333.2A
Other languages
German (de)
English (en)
Inventor
Heiko Zimmermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Original Assignee
Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV filed Critical Fraunhofer Gesellschaft zur Forderung der Angewandten Forschung eV
Publication of EP3471885A1 publication Critical patent/EP3471885A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00—Enclosures; Chambers
    • B01L1/52—Transportable laboratories; Field kits
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/54—Labware with identification means
    • B01L3/545—Labware with identification means for laboratory containers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/028—Modular arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/14—Process control and prevention of errors
    • B01L2200/141—Preventing contamination, tampering
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/023—Sending and receiving of information, e.g. using bluetooth
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/024—Storing results with means integrated into the container
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/54—Labware with identification means

Definitions

  • the invention relates to a sample collection kit, which is set up for the collection of plant samples, in particular for the collection of algae samples for biomedical applications.
  • the width ⁇ ren the invention relates to a method for collection of plant samples using the sample collection kits.
  • Applications of the invention are in the extraction of plant extracts, especially for biomedical applications, e.g. As in the production of alginate granules given.
  • Alginate is a polysaccharide derived from marine algae and has numerous uses in chemical engineering, food technology and biomedicine.
  • alginate is used eg for the production of implants.
  • implants for medical applications for example for use in human implant recipients, high demands (especially Biokompatibi ⁇ formality), purity and stability are placed on the Biofunctionality. It is well known to subject these requirements to alginates undergo predetermined cleaning procedures to minimize variations in composition. Furthermore, it is off
  • DE 10 2005 040 872 B3 discloses documenting the collection site (geographical location of the algae harvest) and sample data from the collection site and from the transport of the algae to the consumer in order to minimize fluctuations in the biofunctionality of the alginates obtained from the algae.
  • the algae are harvested been manually as ⁇ derverwendbaren tools by fishermen.
  • the fishermen also carry out a first treatment of the collected algae and possibly one Drying by.
  • the collected algae are sent to the consumer in a sample container, which may be equipped with sensors and a data logger according to DE 10 2005 040 872 B3, from which the alginate is extracted from the dried algae, eg for the production of an implant is won.
  • the object of the invention is to provide an improved Probensam- mel kit and an improved method for collecting
  • sample collection kit and the method should in particular ⁇ special the production of alginate with increased reliability and reproducibility of the collection and processing of algae, increased reproducibility of the composition and / or reduced fluctuations in biofunctionality allow.
  • standards for quality assurance such as GMP standards, can be improved.
  • the above object is ge ⁇ dissolved by a sample collection kit, which is adapted for collection of plant samples, in particular of algae samples and a sensor system having multiple sensors for detecting sample data, working medium, the for the primary collection (harvesting), transport and processing of the plant samples, eg for obtaining a plant extract, and identification marks with identification data of the working materials.
  • the sample collection kit is suitable for all phases from the collection of plant samples to the extraction of the plant extract.
  • all Agriculturemit ⁇ tel in particular tools and auxiliary equipment, which are to Her ⁇ position of the plant extract required, included in the sample collection kit and at least the tools by means of the identification mark identified.
  • This allows to provide the plant extract together with sample data and identifi ⁇ z istsquel that zenex Exercises allow full characterization of the collection and manufacturing process of the plant-.
  • the individual steps of the collection, transportation and processing of plants per ⁇ ben be unified by providing the working medium, so that variations in the natural sheep ⁇ th of the collected samples and plants of the plant-produced zenextract or substances obtained therefrom, in particular fluctuations in biofunctionality. If in the application of gewonne with the sample collection kit ⁇ nen plant samples contamination or errors show gron- nen their causes because of the complete sample data and identification data to the collection of plant samples be traced.
  • the sample collection kit generally provides a set of tools for collecting, transporting and processing the
  • the sample collection kit comprises at least one sample container for receiving the Depro ⁇ ben.
  • the sample container is preferably adapted to be liquid-tight container ⁇ the plant samples and includes, for example a bag made of a plastic film.
  • the sample container provides the maintenance of a moist environment and protection against the ingress of undesirable contaminants during transport.
  • the sample collection kit comprises the sensor arrangement with a plurality of sensors with which sample data, the properties of the collected plant samples or the type of sample collection represent, in particular physical and / or chemical properties of the plant samples and / or physical and / or chemical conditions of the Collection, of
  • Transports and processing of the plant sample represent ⁇ ren, can be detected, and a data recording device (with at least one data logger), which is set up to record the sample data.
  • the aufoniaseinrich- tung may include a data logger, which is firmly connected to the sample collection kit, and one or more data loggers which are provided for connection to sample containers in the sample collection kit to réelle data during transport ⁇ drawing.
  • the sample collection kit includes a work ⁇ convincing arrangement that includes collecting tools and editing tools.
  • the collection tools are adapted for harvesting the plant samples.
  • the user such as in the collection of algae, the fisherman, provided uniform collection tools, whereby the conditions of collection of plant samples are standardized.
  • the processing tools are adapted for processing, in particular extract extraction, of the plant samples at a processing location separate from the natural collection location, in particular in a processing laboratory.
  • the processing tools encompass the working means and articles of daily use of the user of the sample collection kit acting on the plant samples during the processing.
  • the machining tools By specifying the machining tools ⁇ the advantage of a uniform and reproducible processing to extraction of the plant extract is obtained as in the collecting tools.
  • the collection tools and the processing tools are disposable work tools that are used once to collect and process the plant samples of a common batch.
  • the sample collection kit further comprises a tool assembly with auxiliary devices that are configured to be used in the collection, transportation and processing of plant samples and particularly for a documentation of physi ⁇ rule and / or chemical conditions during these steps.
  • the sample collection kit comprises a Behdroitin ⁇ direction for receiving the collecting tools, the machining ⁇ tools and the auxiliary devices in an iso ⁇ profiled on the ambient condition.
  • the container device preferably is modular, forms a package of Probensam- mel kit.
  • the container device provides protection of the working means prior to the use of the sample collection kit and a defined arrangement of the working means, whereby the application of the sample collection kit, eg by specifying an order of application of collection or processing Be ⁇ tools simplified.
  • the above object is achieved by a sample collection method for collecting plant samples using the sample collection kit according to the first general aspect of the invention.
  • the sample collection procedure involves the collection of plant samples at a natural sample collection site using the collection tools, the
  • Plant samples are transferred to the at least one sample container and sample data is recorded. Subsequently, the transport of the at least one sample container and the sample processing kit to a processing laboratory, wherein the sample data with data on the physical and / or chemical conditions of transport, in particular the transport route and the transport time are supplemented during transport. Subsequently, the production of a plant extract takes place in the processing laboratory using the processing tools. During processing, the sample data will be containing information about the physical
  • the finished plant extract is provided along with a data set that includes the sample data and the sample collection kit identification data.
  • the invention of the harvesting and preparation process of plant samples with respect to the purity of the plant extract and the Documentation and traceability of the individual process steps significantly improved.
  • the inventors have Festge ⁇ assumed that variations in the biofunctionality of Pflan zenproben ⁇ , obtained by conventional techniques, by contamination of the working fluid, possibly reused or insufficiently cleaned tools Undefi ⁇ ned and inadequately documented parameters of the total ⁇ process (harvest site Harvest time, transport time, physical and / or chemical environmental parameters, etc.) and the use of non-uniform work equipment.
  • the sample collection kit simplifies the production of material with reproducible properties.
  • An important advantage of the sample collection kit, as recognized by the inventors, is that all of the sample collection kit requires
  • the sample collection kit a set of Ar ⁇ beitsschn for the full one-way use of the tool tools and consumables represent.
  • Assistive devices such as documentation devices, especially satellite receiver, watches, communications equipment, lamp) and sensors, however, can for the one-way or multiple use.
  • sample Sammelkits Another advantage of the sample Sammelkits is to it ⁇ creased safety for the user because it works with emperli ⁇ chen, new, tested tools and optional (by the sample collection kit with an emergency system communication ⁇ device, first-aid kit ) Is provided.
  • the sample collection kit further includes consumables useful in harvesting and processing the plant samples.
  • the consumables include, for example, water, disinfectants and / or test substances, eg. B. for the detection of foreign substances.
  • the container device is arranged for receiving the collection tools and the processing tools before the harvest of the plant samples in a sterile state.
  • the collection tools and the processing tools are taken apart materially from the environment.
  • the container device is preferably provided with a seal which is provided for destruction only at the beginning of the harvest.
  • the container device of the sample collection kit is constructed from a plurality of container modules, which include a Harvesting module, a documentation module and a processing module include.
  • Each module is a separate container which eclip ⁇ closed container which all working means for the individual phases of the collection and processing and / or
  • the harvesting module is configured for receiving the Sam ⁇ melwerkmaschinee.
  • the harvesting module contains picking elements adapted to the number, size and shape of the required collection tools. An inadvertent recording of unsuitable collection tools is advantageously avoided.
  • the processing module is configured for receiving the Bear ⁇ beitungswerkmaschinee. Even in the case of machining ⁇ performance tools specific Recordin ⁇ meiata are provided in the processing module, making the use of unsuitable processing tools is avoided.
  • the documentation module preferably includes the auxiliary devices that are used when needed in the collection and processing of the plant samples.
  • the container device can be equipped with a charging interface, via which electrically operated auxiliary devices of the sample collection kit and optionally also electrically operated tools can be supplied with an electrical charging current.
  • a charging interface comprises a charging socket, which is arranged for receiving the plug of a charging cable on an outer ⁇ side of the container device.
  • the container device can be equipped with a wireless or line-bound data interface, via which a data exchange between the data recording device and an external control device, for. B. an external computer.
  • the collection tools in the harvesting module and the Be ⁇ processing tools in the processing module can be arranged side by side so that they form a series according to the order of use of the respective tools in the collection and processing of plant samples.
  • the harvesting module and the processing module provide the tools according to the sequence of the method according to the invention as a workflow, which advantageously the reliability and Reprodu ⁇ zieriana the use of the sample collection kit can be improved.
  • the harvesting module may be equipped with a release device, which opens the
  • Harvest module allows only at a predetermined geographical sample collection location and otherwise blocked a Ver ⁇ conclusion of the harvest module.
  • the release device and its operation can, for. B. be realized as in
  • the container modules are detachably connected to each other.
  • the container modules are preferably on their outer sides with matching connecting elements, for. B. locking elements.
  • the sample collection kit comprises, for example, a stack of composite Be ⁇ pliermodule. If the container modules have carrier handles, there are advantages for handling the sample collection. Kits and the individual container modules during the phases of collection, transport and processing of convincedpro ⁇ ben.
  • the container modules Preferably, the container modules have the same shape and size, so that the combinability of the container modules to create sample collection kits for various tasks is simplified.
  • the container modules each have a holding platform with receiving elements, for.
  • a trans ⁇ port of tools in the loading fixed state allows improves the safety of the user and may lack a tool easily recognizable.
  • Particularly preferred form-locking receiving elements are provided, the shape of which is adapted to the shape of the working means. If the container device is equipped with multiple container modules, the charging interface is preferably provided at Do ⁇ kumentationsmodul, since this electrically operated auxiliary devices contains.
  • the charging interface can be provided on another container module.
  • the container device may further be equipped with an emergency module containing medical aids for the user of the sample collection kit.
  • the emergency module (first aid kit) is preferably for a Coupled with the other container modules, in particular an integration in the stack of container modules configured.
  • the working means and sensors in the sample collection kit can advantageously be selected depending on the specific task, in particular in the collection and processing of algae.
  • the components are Wenig ⁇ equipped least one of the following features.
  • the sensors preferably comprise at least one temperature sensor, at least one humidity sensor, at least one UV sensor and / or at least one salinity sensor.
  • the temperature sensor With the temperature sensor, the temperature can be measured during the collection of plant samples, during transport and optionally also during processing.
  • the measured temperature values are stored as sample data from the data recorder.
  • the humidity sensor is preferably used for detecting moisture in the environment of the collected plant samples
  • each sample container is equipped with a humidity sensor.
  • the moisture data acquired with the humidity sensor are also stored as sample data during collection of the plant samples and their transport with the data logger.
  • the humidity sensor allows the detection of damage to the sample container during transport ⁇ ports. If the sample container becomes damaged, the plant samples will dry out, as can be seen in the recorded moisture data.
  • the UV sensor is a radiation sensor that records natural UV radiation when collecting and transporting plant samples.
  • the UV sensor also coupled to the sample container to detect UV exposure of the collected plant samples during transport.
  • the Salinticianssensor adapted for detecting the salinity of the sea at the collection and / or the collected plants per ⁇ ben.
  • the salinity data stored during collection and transport enable the characterization of the plant samples and the detection of the possible ingress of foreign substances.
  • the collecting tools of the sample collection kits include preferential ⁇ , at least one bus network (z. B. landing net for the collection of algae), at least one harvesting knife, a thickness measurement device, such as a slide gauge, (for detecting the thickness of the collected plant z. B. the seaweed stems), and Probenfla ⁇ rule to hold reference samples such as environmental samples such as seawater from around the collected algae.
  • the machining tools comprise paring knife, an incision ⁇ board, and protective clothing for the user of the sample collection kits, in particular in the processing in the processing laboratory, such as a hood, gloves, a mask and a
  • a suction filter for receiving dried plant constituents may be provided after a drying process as a processing tool.
  • the auxiliary devices in the sample collection kit preferably comprise a satellite receiver, a camera, a clock, and / or
  • At least one of the collection tools and / or the machining tools with a use indicator may be Equipped which is incorporated ⁇ directed to display a tool use.
  • the usage indicator in particular a ⁇ sersensor What is disposed on a surface of the respective tool.
  • a chemical indicator is provided, the z. B. reacts to contact with water.
  • Tool with water discolored the usage indicator, so that the user can tell whether the tool in question has already been used.
  • an electronically working ⁇ the user indicator an electronic circuit is provided, which in a contact z. B. with water undergoes a state change that is electronically readable.
  • the detection of the successful use of tools can also be used to block the data logger.
  • the at least one data logger can be designed for write protection, which is activated as soon as a last tool has been used at a certain working cycle .
  • at least one of the collection tools and / or the processing tools have a chemical sensor for detecting foreign substances, such.
  • the chemical sensor based z. B on a color change, contamination of the plant sample detectable.
  • Plant extract packed in an extract container which is provided with the identification data of the sample collection kit and the Pro ⁇ benaries.
  • the composite of the plant extract and the identification and sample data remains ⁇ during further use at the consumer, for example, obtained at the manufacturer of the implant.
  • one of the container modules of the sample collection ⁇ kit is used for receiving the extract container forradtrans ⁇ port from the processing laboratory to the consumer.
  • the processing module can be sent to the consumer together with the extract container and the data recording device.
  • FIG. 1 shows a schematic perspective view of an off ⁇ management form of sample collecting kit according to the invention with a stack of several Benzol ⁇ termodulen;
  • FIG. 2 shows a schematic illustration of the contents ei ⁇ nes harvest module of the sample collection kits
  • Figure 4 a schematic illustration of the contents of
  • the algae samples are preferably obtained from macroalgae, in particular from the algae species Laminaria.
  • the implementation of the invention is not limited to this example, but according to other plant ⁇ samples possible.
  • the tools for collecting algae samples included in the sample collection kit are mentioned by way of example.
  • the implementation of the invention is not on the
  • FIGS. 2 to 4 can alternatively or additionally be equipped with parts from the list of working means mentioned below. Details of the collection and processing of algae samples and the selection of suitable algae species are not explained below, as far as they are known and customary.
  • the sample collection kit 100 can be modified and / or supplemented to improve the safety of a correct use.
  • the sample collection kit 100 may be provided with access control means, e.g. As a wireless, in particular using a transponder or RFID chip, or releasable with a key (or combination lock mechanical key) be ⁇ campus lock, a monitoring device for detecting the completion of the feed, eg. B. with space sensors on individual receiving elements in the container modules, and / or a display device for displaying the operating state, for. B. state of charge, the sample collection kit 100 may be equipped.
  • access control means e.g. As a wireless, in particular using a transponder or RFID chip, or releasable with a key (or combination lock mechanical key) be ⁇ nselbaren lock
  • a monitoring device for detecting the completion of the feed eg. B. with space sensors on individual receiving elements in the container modules
  • / or a display device for displaying the operating state, for. B. state of charge
  • the container means 70 comprises a stack of several containers modules 71, 72, 73, and an emergency trap module 78th
  • the container modules 71, 72, 73 are coupled in the closed state mutually complementary connecting elements 77, which are arranged on the outer sides of Be ⁇ federermodule 71, 72, 73rd
  • the container modules comprise a harvesting module 71 (see FIG. 2), a documentation module 72 (see FIG. 3) and a processing module 73
  • the container modules 71, 72, 73 are marked graphically and / or textually (eg 71: "SEA”, 72: “DOC”, 73: “LAB”, 78: “SOS”).
  • Each of the container modules 71, 72, 73 is a box (case), z. As plastic and / or metal, with a bottom portion 71A and a lid portion 71B, which are connected to each other via hinges. When closed, the container modules 71, 72, 73 are closed on all sides, so that their interior can be materially separated from the environment and provided in a sterile state until the first opening.
  • Carrier handles 75 on end faces and / or the cover parts 71B are designed for the manual transport of the container modules 71, 72, 73 individually or in combination.
  • Identification marks 80 on the outsides of the container modules 71, 72, 73 include waterproof marks, e.g. As barcodes, QR codes, wirelessly readable memory, in particular transponder, and / or strings of numbers and / or letters containing identification data of the sample collection kit 100.
  • the 100 ⁇ together amount added in the sample collection kit, removable from the container modules working media are the same with identification marks 80 or a modified type containing the same identification data of the sample collection kit 100.
  • the documentation module 72 is equipped on its outer surface of the associated bottom part with a charging interface 74 in the form of a charging socket (eg, IEC connector socket) via the electrically operated auxiliary equipment (eg satellite receiver, mobile phone) in the documentation module 72 via an internal Charger with electric charging current can be supplied. This ensures that all devices can be made operational with the harvest, without the seal of the sample collection kits 100 to beCdi ⁇ . Further, provided on the documentation module 72, a data ⁇ interface 79, on the data from an inter- nal data recorder can be read out.
  • a charging interface 74 in the form of a charging socket (eg, IEC connector socket) via the electrically operated auxiliary equipment (eg satellite receiver, mobile phone) in the documentation module 72 via an internal Charger with electric charging current can be supplied. This ensures that all devices can be made operational with the harvest, without the seal of the sample collection kits 100 to beCdi ⁇ .
  • a data ⁇ interface 79 on the data from an inter- nal data record
  • FIG. 2 schematically shows the harvesting module 71 of the sample collecting kit 100 in the opened state with a plan view of the bottom part 71A and the cover part 71B.
  • a holding platform 76 is provided with receiving elements 76A for the collection tools 41, 42, which are used for harvesting the algae samples, and for the sample containers 10.
  • the holding platform 76 is an adapted rigid foam bed in which the receiving elements 76A are formed as recesses with the outer shape of the individual components.
  • harvesting module 71 is a schematic ⁇ schematically shown release device 71C, which is coupled to a satellite receiver and blocks a closure of ERNT ⁇ emoduls 71 until the harvest module 71 is located at a predetermined geographic Probensammelort.
  • the collecting tools in the bottom portion 71A comprise two Erntemes ⁇ ser 42, a thickness gauge 43, marker elements 44, a rinse or spray bottle 45, two vials 46 and foil-
  • the harvesting blades 42 are shown by way of example with Ge ⁇ consumption indicators 42 A, the z. B. have a color change in contact of the harvesting knife 42 with water. Furthermore, the harvesters 42 may be equipped with chemical sensors for foreign substance detection.
  • Thickness gauge 43 is a ruler or caliper that measures the thickness of the harvested algae samples. The measured thicknesses are recorded with the recording means for written documentation in the documentation module 72.
  • the marking elements 44 are bands which each carry an identification mark with the identification data of the sample collection kit 100 and are provided for fixing to the sample containers 10.
  • the marking elements 44 can be provided simultaneously for a closure of the sample container 10.
  • the rinsing bottle 45 contains salt-free or saline water for rinsing the harvested algae samples prior to being taken up in one of the sample containers 10.
  • the sample bottles 46 may contain environmental samples, e.g. B Water samples taken at the place of harvest and transported together with the harvested algae samples to the processing laboratory.
  • the film material 47 is used as auxiliary material, for. B. intended for packaging purposes.
  • the collection tools in the lid portion 71B comprise two collection nets 41 for harvesting the algae samples from the seawater.
  • the documentation module shown schematically in Figure 3 in the open state 72 has in the bottom part 72A a Garplatt ⁇ form 76 with receiving elements 76A for the auxiliary devices 61, 62, in particular for documentation purposes, and in the lid portion 72B a compartment 72C for AufZeichnungsstoff 64 for written documentation, eg. B. a writing pad.
  • the auxiliary devices in the bottom part 71A comprise at least one satellite receiver 61, a camera 62, a clock 63, a modem. biltelephone 65, a printed workbook 66, a
  • the charger 68 is connected on the one hand to the charging interface 74 and on the other hand with the electrically operated auxiliary devices with electric batteries via charging cable (not shown) coupled.
  • the protective clothing 69 comprises, for example, a hood or a hair net, a surgical mask and gloves for the user when processing the algae samples and preparing alginate granules.
  • a sensor arrangement with a plurality of schematically shown sensors 21, 22,... And a data recording device 30 (data logger) for recording sample data are arranged in the bottom part 71A.
  • the data recorder 30 is connected to the data interface 79.
  • Wei ⁇ tere data logger (not shown) are provided for connection to sensors and for insertion into the sample container 10 with algae samples after harvest during transport tochiesla- boron.
  • the sensors 21, 22, ... include z.
  • Humidity sensors 21 for measuring moisture in the sample containers 10 after harvest and during transport
  • a temperature sensor 22 for air and / or water temperature measurement during use of the sample collection kit 100
  • UV sensors 23 for UV radiation measurement on the sample containers 10 after harvest and during transport and / or a salinity sensor 24.
  • other or further auxiliary devices may be included in the documentation module 72 or other container modules.
  • the data recorder 30 may be replaced by a computer, and / or the components 61, 62, 63 and 65 and the data recorder 30 may be integrated in a common device such as a microcomputer or a smartphone.
  • the processing module 73 in the base part 73A comprises two holding platforms 76.1, 76.2 with receiving elements 76A for the processing tools 51, 52,... And optionally further auxiliary devices and in the lid part 73B a compartment 73C for further recording means 64 for written documentation or written Working instructions.
  • the Halteplatt ⁇ forms 76.1, 76.2 form two, partially overlapping planes with different processing tools 51, 52, ....
  • the editing tools include z. B. two peeling and / or chopping knives 51, a cutting board 52, filter material 53, pre ⁇ storage tank 54 for treatment liquids, especially disinfectant, a cleaning device 55, in particular ei ⁇ ne brush, and extract container 56, 57, such. B. cans 56 and bags 57.
  • the peeling and / or chopping blades 51 are shown for example with chemical sensors 51A for foreign matter detection, the z. B. have a color change in the presence of animal protein in the plant samples.
  • the peeling and / or chopping knife 51 can be equipped with ceremonisindika ⁇ tors.
  • sample collection kit 100 for a content according to the following list of working ⁇ forward: - 1 printed instruction manual 66,
  • the collection and processing of algae samples for the extraction of alginate extract includes, for. For example, the following steps.
  • the sample collection kit 100 Before the harvest phase on a coast or on the open sea, the sample collection kit 100 is loaded. During the harvest , a continuous time measurement takes place in the process
  • Hand brush 55 and a micro-cutting knife can be used. This is followed by a pruning and peeling of the algae, a sample of water with tap water and a fine cut of the algae to algae granules that may be subjected to a precipitation step to obtain the alginate.
  • the algal granules or alginate is dried in a drying cabinet of the processing laboratory and removed with a Saugeinrich ⁇ tion and the filter 53 from the oven.
  • the dried algae granules are packed in the extract containers 56, 57 under vacuum.
  • the extract containers 56, 57 are provided with unique code of the sample collection kit 100 (eg bar code label) and sent to the consumer together with a thermometer (min-max).

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Biomedical Technology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Materials For Medical Uses (AREA)
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  • General Physics & Mathematics (AREA)
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Abstract

L'invention concerne un kit de collecte d'échantillons (100) destiné à collecter des échantillons de plante, en particulier des échantillons d'algue pour des utilisations médicales. Le kit comprend au moins un récipient à échantillons destiné à recevoir des échantillons de plantes, plusieurs capteurs, au moyen desquels des données peuvent être acquises, un système d'enregistrement de données destiné à enregistrer les données d'échantillons, un ensemble d'outils comportant des outils de collecte conçus pour récolter les échantillons de plante, et des outils de traitement conçus pour traiter les échantillons de plante, un ensemble d'appareils comprenant des appareils auxiliaires pouvant être utilisés pour la collecte, le transport et le traitement des échantillons de plante, un système de récipient (70) conçu pour recevoir l'ensemble d'outils et l'ensemble d'appareils dans un état isolé par rapport à l'environnement, et des marques d'identification (80) contenant des données d'identification et appliquées sur le ou les récipients à échantillons (70), les outils de collecte et les outils de traitement. L'invention concerne également un procédé de collecte d'échantillons.
EP17726333.2A 2016-06-17 2017-06-01 Kit de collecte d'échantillons et procédé de collecte d'échantillons de plante, en particulier d'échantillons d'algue Withdrawn EP3471885A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16001367.8A EP3257586B1 (fr) 2016-06-17 2016-06-17 Kit de collecte d'echantillons et procede destine a collecter des echantillons vegetaux, en particulier des echantillons d'algues
PCT/EP2017/063334 WO2017215939A1 (fr) 2016-06-17 2017-06-01 Kit de collecte d'échantillons et procédé de collecte d'échantillons de plante, en particulier d'échantillons d'algue

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EP3471885A1 true EP3471885A1 (fr) 2019-04-24

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EP16001367.8A Active EP3257586B1 (fr) 2016-06-17 2016-06-17 Kit de collecte d'echantillons et procede destine a collecter des echantillons vegetaux, en particulier des echantillons d'algues
EP17726333.2A Withdrawn EP3471885A1 (fr) 2016-06-17 2017-06-01 Kit de collecte d'échantillons et procédé de collecte d'échantillons de plante, en particulier d'échantillons d'algue

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EP16001367.8A Active EP3257586B1 (fr) 2016-06-17 2016-06-17 Kit de collecte d'echantillons et procede destine a collecter des echantillons vegetaux, en particulier des echantillons d'algues

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US (1) US10967378B2 (fr)
EP (2) EP3257586B1 (fr)
JP (1) JP6997728B2 (fr)
KR (1) KR102406364B1 (fr)
CN (1) CN109475876B (fr)
CL (1) CL2018003589A1 (fr)
ES (1) ES2791285T3 (fr)
WO (1) WO2017215939A1 (fr)
ZA (1) ZA201808397B (fr)

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DE102020130008A1 (de) 2020-11-13 2022-05-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Authentifizierbares Probensammel-Kit zur Pflanzenproben-Sammlung und dessen Anwendung
CN112683572B (zh) * 2021-01-11 2022-11-04 湛江国联水产开发股份有限公司 一种可防样品混杂的藻类检测用连续取样装置

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US3648159A (en) * 1970-03-11 1972-03-07 Us Air Force Portable, self-contained system for analyzing biological fluids or the like
US4303610A (en) * 1980-05-19 1981-12-01 Pennzoil Company Test kit for field analysis of plant tissue magnesium and calcium
US20060286606A1 (en) * 2005-06-17 2006-12-21 Oliver Troy L Clandestine Laboratory (Clan-Lab) Home Test Kit system, protocol, method and apparatus
DE102005040872B3 (de) 2005-08-29 2007-04-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Probensammelverfahren und entsprechende Probensammeleinrichtung, insbesonere zum Sammeln von Algenproben
US8802370B2 (en) * 2008-05-23 2014-08-12 Strand Diagnostics, Llc Method and apparatus to minimize diagnostic and other errors due to transposition of biological specimens among subjects
CN201724839U (zh) * 2010-03-22 2011-01-26 杨扬 便携移动式水质采样专用工具箱
KR20110107652A (ko) 2010-03-25 2011-10-04 주식회사 환경바이오 휴대형 조류 측정장비
WO2012147261A1 (fr) * 2011-04-28 2012-11-01 村田機械株式会社 Système de réception d'articles, et procédé de réception et de chargement d'articles
US20150293070A1 (en) 2011-06-15 2015-10-15 Gary L. Emmert On-site kit for analysis of disinfectant byproducts species and amounts thereof in drinking water supplies
DE102011109332A1 (de) * 2011-08-03 2013-02-07 Eppendorf Ag Laborvorrichtung und Verfahren zur Behandlung von Laborproben
CN104401589A (zh) * 2014-11-24 2015-03-11 黄蕊萍 感染科用护理采集箱

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KR102406364B1 (ko) 2022-06-08
EP3257586A1 (fr) 2017-12-20
WO2017215939A1 (fr) 2017-12-21
CN109475876B (zh) 2021-10-01
CL2018003589A1 (es) 2019-03-08
US10967378B2 (en) 2021-04-06
KR20190020734A (ko) 2019-03-04
JP2019521991A (ja) 2019-08-08
JP6997728B2 (ja) 2022-01-18
CN109475876A (zh) 2019-03-15
ES2791285T3 (es) 2020-11-03
US20190184399A1 (en) 2019-06-20
ZA201808397B (en) 2020-02-26
EP3257586B1 (fr) 2020-03-25

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