EP3452500A4 - Proliferation von mesenchymalen stammzellen - Google Patents
Proliferation von mesenchymalen stammzellen Download PDFInfo
- Publication number
- EP3452500A4 EP3452500A4 EP17793552.5A EP17793552A EP3452500A4 EP 3452500 A4 EP3452500 A4 EP 3452500A4 EP 17793552 A EP17793552 A EP 17793552A EP 3452500 A4 EP3452500 A4 EP 3452500A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- stem cell
- cell proliferation
- mesenchymal stem
- mesenchymal
- proliferation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000004663 cell proliferation Effects 0.000 title 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3616—Blood, e.g. platelet-rich plasma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/115—Platelets, megakaryocytes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Urology & Nephrology (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HUP1600306 | 2016-05-06 | ||
PCT/US2017/031585 WO2017193134A1 (en) | 2016-05-06 | 2017-05-08 | Mesenchymal stem cell proliferation |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3452500A1 EP3452500A1 (de) | 2019-03-13 |
EP3452500A4 true EP3452500A4 (de) | 2019-12-11 |
Family
ID=89720150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP17793552.5A Pending EP3452500A4 (de) | 2016-05-06 | 2017-05-08 | Proliferation von mesenchymalen stammzellen |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP3452500A4 (de) |
WO (1) | WO2017193134A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109943471A (zh) * | 2017-12-21 | 2019-06-28 | 北京中原合聚经贸有限公司 | 一种间充质干细胞过滤灌流培养制备装置 |
CN110585243A (zh) * | 2019-08-12 | 2019-12-20 | 丰泽康生物医药(深圳)有限公司 | 用于治疗糖皮质激素依赖性皮炎的多潜能细胞活性物与富血小板血浆复合物及制法和应用 |
US20240141296A1 (en) * | 2021-02-25 | 2024-05-02 | Swedish Stromabio Ab | Compositions and methods for proliferation of mesenchymal stromal cells |
CN113249332A (zh) * | 2021-07-15 | 2021-08-13 | 北京大学第三医院(北京大学第三临床医学院) | 一种alpl基因缺失骨髓间充质干细胞的建立方法 |
CN114869912A (zh) * | 2022-05-23 | 2022-08-09 | 西安中美弘康生物科技有限公司 | 一种人间充质干细胞复合nPRF制剂的制备方法 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090010896A1 (en) * | 2007-07-05 | 2009-01-08 | Centeno Christopher J | Methods and compositions for optimized expansion and implantation of mesenchymal stem cells |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201506259WA (en) * | 2013-02-12 | 2015-09-29 | Lacerta Technologies Inc | Serum fraction of platelet-rich fibrin |
-
2017
- 2017-05-08 WO PCT/US2017/031585 patent/WO2017193134A1/en active Search and Examination
- 2017-05-08 EP EP17793552.5A patent/EP3452500A4/de active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090010896A1 (en) * | 2007-07-05 | 2009-01-08 | Centeno Christopher J | Methods and compositions for optimized expansion and implantation of mesenchymal stem cells |
Non-Patent Citations (4)
Title |
---|
CHI-SHENG CHIEN ET AL: "Incorporation of exudates of human platelet-rich fibrin gel in biodegradable fibrin scaffolds for tissue engineering of cartilage", JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B: APPLIED BIOMATERIALS, vol. 100B, no. 4, 25 May 2012 (2012-05-25), pages 948 - 955, XP055111158, ISSN: 1552-4973, DOI: 10.1002/jbm.b.32657 * |
See also references of WO2017193134A1 * |
SU C Y ET AL: "In vitro release of growth factors from platelet-rich fibrin (PRF): a proposal to optimize the clinical applications of PRF", ORAL SURGERY, ORAL MEDICINE, ORAL PATHOLOGY, ORAL RADIOLOGY AND ENDODONTICS, MOSBY-YEAR BOOK, ST. LOUIS, MO, US, vol. 108, no. 1, 1 July 2009 (2009-07-01), pages 56 - 61, XP026434162, ISSN: 1079-2104, [retrieved on 20090517] * |
THIERRY BURNOUF ET AL: "Human blood-derived fibrin releasates: Composition and use for the culture of cell lines and human primary cells", BIOLOGICALS, vol. 40, no. 1, 1 January 2012 (2012-01-01), pages 21 - 30, XP055111162, ISSN: 1045-1056, DOI: 10.1016/j.biologicals.2011.09.017 * |
Also Published As
Publication number | Publication date |
---|---|
WO2017193134A1 (en) | 2017-11-09 |
EP3452500A1 (de) | 2019-03-13 |
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Legal Events
Date | Code | Title | Description |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE INTERNATIONAL PUBLICATION HAS BEEN MADE |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
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17P | Request for examination filed |
Effective date: 20181206 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
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RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: SIMON, MELINDA Inventor name: LACZA, ZSOMBOR Inventor name: HORNYAK, ISTVAN |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
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DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20191113 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61L 27/36 20060101ALI20191107BHEP Ipc: A61K 38/18 20060101ALI20191107BHEP Ipc: A61K 35/28 20150101ALI20191107BHEP Ipc: A61P 19/00 20060101ALI20191107BHEP Ipc: C07K 14/75 20060101AFI20191107BHEP Ipc: C12N 5/0775 20100101ALI20191107BHEP Ipc: A61K 38/36 20060101ALI20191107BHEP Ipc: A61L 27/54 20060101ALI20191107BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
17Q | First examination report despatched |
Effective date: 20210503 |
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STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |