EP3412590B1 - Container for packaging a liquid drop dispenser, reversibly deformed by air inlet - Google Patents
Container for packaging a liquid drop dispenser, reversibly deformed by air inlet Download PDFInfo
- Publication number
- EP3412590B1 EP3412590B1 EP18183420.1A EP18183420A EP3412590B1 EP 3412590 B1 EP3412590 B1 EP 3412590B1 EP 18183420 A EP18183420 A EP 18183420A EP 3412590 B1 EP3412590 B1 EP 3412590B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- container
- liquid
- drop
- packaging
- membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000007788 liquid Substances 0.000 title claims description 109
- 238000004806 packaging method and process Methods 0.000 title claims description 18
- 239000006196 drop Substances 0.000 claims description 40
- 239000012528 membrane Substances 0.000 claims description 38
- 230000002209 hydrophobic effect Effects 0.000 claims description 20
- 238000012384 transportation and delivery Methods 0.000 claims description 17
- 230000000694 effects Effects 0.000 claims description 8
- 238000007789 sealing Methods 0.000 claims description 8
- 230000002441 reversible effect Effects 0.000 claims description 7
- 230000002269 spontaneous effect Effects 0.000 claims description 6
- 238000011144 upstream manufacturing Methods 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 5
- 239000003889 eye drop Substances 0.000 claims description 5
- 229940012356 eye drops Drugs 0.000 claims description 5
- 239000003186 pharmaceutical solution Substances 0.000 claims description 5
- 239000011148 porous material Substances 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 4
- 238000000465 moulding Methods 0.000 claims description 4
- 239000004698 Polyethylene Substances 0.000 claims description 3
- 230000000149 penetrating effect Effects 0.000 claims description 3
- -1 polyethylene Polymers 0.000 claims description 3
- 229920000573 polyethylene Polymers 0.000 claims description 3
- 230000000844 anti-bacterial effect Effects 0.000 claims description 2
- 238000009736 wetting Methods 0.000 claims 1
- 239000003570 air Substances 0.000 description 16
- 238000009826 distribution Methods 0.000 description 16
- 239000003795 chemical substances by application Substances 0.000 description 6
- 230000006835 compression Effects 0.000 description 6
- 238000007906 compression Methods 0.000 description 6
- 238000003860 storage Methods 0.000 description 6
- 239000012080 ambient air Substances 0.000 description 5
- 230000002427 irreversible effect Effects 0.000 description 5
- 239000000463 material Substances 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 238000004321 preservation Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000000284 resting effect Effects 0.000 description 2
- 239000004695 Polyether sulfone Substances 0.000 description 1
- 230000003042 antagnostic effect Effects 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 239000003999 initiator Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 229920006122 polyamide resin Polymers 0.000 description 1
- 229920006393 polyether sulfone Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 230000000135 prohibitive effect Effects 0.000 description 1
- 238000007348 radical reaction Methods 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D47/00—Closures with filling and discharging, or with discharging, devices
- B65D47/04—Closures with discharging devices other than pumps
- B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
- B65D47/18—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages for discharging drops; Droppers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
- B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
- B05B11/04—Deformable containers producing the flow, e.g. squeeze bottles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
- B65D1/32—Containers adapted to be temporarily deformed by external pressure to expel contents
Definitions
- the invention relates to the field of packaging and distribution of liquids, such as pharmaceutical solutions and in particular eye drops.
- Its object is a container equipped with a dispensing head, which is organized to contain a liquid while protecting it from the external environment and to deliver this liquid in a controlled manner, drop by drop in particular.
- Receptacles are known for containing a liquid, which are organized to preserve this liquid from the external environment and to deliver it in a controlled manner, in particular drop by drop.
- the applications of such containers are numerous, and a preferred application, but not restrictive as regards the scope of the present invention, lies in the storage and distribution of a pharmaceutical solution, eye drops in particular.
- the preservation of the liquid With regard to the preservation of the liquid, it must be protected from the external environment by avoiding its contact with the ambient air which is likely to contain polluting agents, bacteria in particular.
- the container For the distribution of the liquid, it is common to give the container a deformable character making it possible to reduce its capacity, at least temporarily, to evacuate the liquid which it contains.
- Such containers are more precisely flexible wall, to cause an evacuation of the liquid from a compression exerted by the user on this wall, and they are equipped with a dispensing head, to achieve the two objectives that are the preservation and controlled distribution of liquid.
- the container an irreversible, or almost irreversible, deformable character.
- An internal wall of the container delimiting the capacity for receiving the liquid is organized as a bellows, and is enveloped by an external sheath.
- This container also contains a filter membrane which has an air-impermeable nature, to prevent an admission of outside air to the liquid contained in the container, under the effect of a withdrawal of the liquid delivered.
- a filter membrane which has an air-impermeable nature
- a microporous pad acting as a flow regulator is placed in the dispensing head of a container with a strictly irreversible deformation wall.
- An intermediate reserve is made downstream of the pad and upstream of an air-impermeable filter membrane.
- Such a container has a complex structure, and the manufacturing cost, both of the reservoir intended to contain the liquid to be dispensed and of the dispensing head, is high.
- the document FR2770495 discloses a container according to the preamble of claim 1.
- the container According to a second approach, it has been proposed to give the container a capacity for reversible deformation. Reference may in particular be made to the document FR 2 816 600 (Where US 2004/0074925 ), which describes such a container.
- the structure of the dispensing head of this container is simple. It contains a filter membrane which aims to preserve the liquid from pollutants likely to be present in the ambient air. It is also planned to strictly preserve the liquid from the ambient medium before first use.
- the dispensing head is movably mounted on the neck of the receptacle, with a view to perforating a cap extemporaneously during a first dispensing operation.
- the present invention is part of this search for a compromise, and aims to provide a container for packaging a liquid to be distributed dropwise which offers a solution responding to such a compromise.
- the invention relates more specifically to the packaging of a sensitive liquid, such as a pharmaceutical, biological or similar solution, eye drops in particular.
- the inventive approach of the present invention has generally consisted in choosing first of all a container of the type comprising a reservoir with a wall with elastically reversible deformation by admission of air inside the container.
- This choice aims to allow delivery of the liquid under the effect of a pressure exerted against this wall, and to allow a spontaneous return of the container to its initial configuration after delivery of a dose of liquid.
- Such a reservoir with a reversible deformation wall already presents in itself the advantage of a great simplicity of manufacture, compared to irreversible deformation tanks of the prior art, which require a large number of parts and assembly operations.
- such a container according to the present invention will be recognized in that it is equipped with a dispensing head comprising a hollow body which is provided with a nozzle for delivering the liquid and which contains a microporous pad of hydrophobic material. placed downstream of the reservoir across the body of the dispensing head. Said body is assembled irreversibly inside the neck of the container.
- the receptacle with a removable cap for sealing the nozzle which, associated with said microporous pad of hydrophobic material, obstructs the spontaneous flow of the liquid out of the capacity of the receptacle reserved for its storage to the nozzle.
- a removable cap for sealing the nozzle which, associated with said microporous pad of hydrophobic material, obstructs the spontaneous flow of the liquid out of the capacity of the receptacle reserved for its storage to the nozzle.
- the passage of air is allowed by suction through the hydrophobic microporous pad towards the storage capacity after delivery of a dose of liquid, this suction being caused by the elastic return of the wall of the container to its initial conformation. , return by which the container returns to its initial shape notwithstanding a withdrawal of a dose of liquid.
- the microporous pad is preferably made of polyethylene, or similar material, which gives it a hydrophobic character so that it is not wettable, its microporous character nevertheless allowing the passage of the liquid through it, provided that the differential pressure, induced by the pressure exerted by the user, is sufficient.
- Such a configuration of the container, and more particularly the combination between the reversible deformation reservoir, the microporous pad and the tight sealing cap, is quite advantageous. Indeed, when the cap is returned to the sealed position of the nozzle, after the suction of air following the delivery of a dose of liquid and the elastic return of the wall of the container to its initial configuration, it a pressure difference is created between the parts upstream and downstream of the buffer through which a pressure drop is created. This pressure difference prevents the liquid in the container from passing through the pad, even if you accidentally press on the container wall, and it seals the bottle, while protecting the liquid it contains from external contamination. . In addition, such a configuration avoids any stagnation of liquid downstream of the pad, since the non-expelled liquid is sucked back into the capacity of the container.
- the container advantageously meets an objective of the invention, which is to ensure optimum use of all the contents of the reservoir, and this in two different ways.
- the container thanks to its elastically reversible deformation wall, the container retains an intact liquid expulsion capacity until the last drop of liquid.
- the expulsion pressure available in the bottle is always the same throughout use, until the distribution of the last drop.
- there remains downstream of the tampon no drop of liquid liable to be contaminated by external agents, and which should be eliminated before any new distribution of a clean dose.
- the microporous pad through which a pressure drop is created, acts as a flow regulator, which promotes the controlled distribution of doses of liquid. In addition, it prevents the liquid contained in the bottle from flowing when the cap is removed, even when the bottle is in the inverted position, the dispensing head being directed downwards, as long as no pressure is exerted on the wall of the container.
- the dispensing head is preferably equipped with a filter membrane intended to protect the liquid from an admission of polluting agents present in the ambient air, bacteria in particular.
- a membrane is then chosen which is at least partly hydrophilic and at least partly hydrophobic, to allow the passage of liquid and air alternately through it, and which is placed in the distribution head in upstream of the nozzle, between it and the buffer.
- the partially hydrophilic nature of the membrane allows the liquid to pass through it under the effect of the compression exerted in the container by deformation of the wall, while its partially hydrophobic nature allows outside air to enter the container. , when the latter resumes its initial shape elastically after each compression exerted by the user.
- the membrane also advantageously constitutes an additional pressure drop, which ensures, in combination with the hydrophobic microporous pad, that no liquid leakage out of the container occurs until the wall of the container is compressed.
- the invention In order to promote the passage of air through the membrane, the invention then provides that it is possible to keep this dry membrane between two liquid deliveries, when the container is in the resting position on its base, thanks to the presence an intermediate chamber arranged interposed between the microporous pad and the membrane.
- Such an intermediate chamber can also be used to constitute a chamber for regulating the delivery of the liquid.
- it can advantageously be given a volume sufficient to collect at least one drop of liquid to be dispensed during an operation for delivering the liquid to make it drop dropwise from the dispensing head.
- the volume of the intermediate chamber according to the invention also constitutes a reserve of air which, when the nozzle is closed by the cap, maintains a pressure which tends to prevent the liquid from passing through the microporous pad. It will be noted that in association with the intercalary chamber, the character hydrophobic microporous pad promotes a role of obstacle opposing the passage of liquid through it.
- the intermediate chamber according to the invention also constitutes a capacity for receiving the liquid which has not yet passed through the membrane when pressure is ceased to be exerted on the wall of the container.
- the intermediate chamber extends over the entire surface of the membrane and that it is located at an axial distance from it sufficient to promote drying of the membrane as soon as the pressure exerted on the wall of the container ceases after delivery of liquid, and this container is returned to its rest position, resting on its base and the dispensing head at the top.
- any remaining liquid which, not having been expelled, remains contained in the intermediate chamber does not continue to wet the membrane by capillary action.
- the hydrophobic nature of the microporous pad also promotes drying of the membrane.
- the invention has the advantage, in industrial practice, of being free from complex control systems. dynamic closure that was used previously. Thanks to the arrangements provided for by the invention, there is no need for a cap or other tear-off partition, or a valve of another shape, or a procedure for opening the bottle by translation or rotation of the bottle. distribution head with respect to the reservoir container for liquid to be distributed dropwise.
- a microporous pad which is quite suitable in the context of the invention has, for the passage of the liquid in the longitudinal direction, microchannels whose average pore diameter is between 0.3 and 10 microns.
- Such a range of values is particularly suitable in the privileged field of application of the invention, which is the storage and distribution of a pharmaceutical solution, in particular of eye drops.
- microporous pad with a partially hydrophilic and partially hydrophobic membrane, the pore diameter of which is smaller than that of the pad, in particular between 0.1 and 0.2 microns. Improved sealing and flow regulation properties of the dispensing head are thereby obtained in particular.
- the membrane may be made of a polymer material, based for example on a polyamide resin or on a polyether sulfone, which gives it a hydrophilic character. It is then made partially hydrophobic by modifying its structure over part of its surface. Such a modification can be carried out in a manner which is conventional in itself, for example by grafting in the presence of an initiator of radical reactions. The treatment is advantageously carried out so as to make the membrane hydrophobic on a middle band occupying 20 to 50% of its surface which is wetted during the expulsion of the liquid.
- the body is assembled inside the neck by interlocking in close contact.
- the body is preferably elastically deformable for its introduction by force inside the neck of the container, a centering member preferably being provided at the base of the body to facilitate such an introduction in strength.
- This centering member preferably consists of radial junction wings by interlocking the body of the dispensing head on the neck of the container, the wings delimiting hollow sectors between them.
- the outer surface of the body of the dispensing head is advantageously equipped with a peripheral ring coming from said body with which it constitutes a one-piece assembly, this ring preferably being in plurality and axially repeated on the body.
- the body is advantageously obtained by molding, under conditions such as a ring, coming from the joint plane, is radial to its general axis of extension, and in particular where appropriate parallel to the aforementioned peripheral ring.
- This ring resulting from the joint plane is more particularly located at the distal end of the body, at the junction limit of the centering member, in order to best promote the seal between the dispensing head and the container.
- the removable cap for its part is preferably attached to the container by screwing to promote the tightening of the cap on the dispensing head, and therefore the seal between these members.
- the cap advantageously comprises a combination of sealing members associating a pin penetrating inside the nozzle of the dispensing head and a skirt covering this nozzle.
- the pin and the skirt are advantageously derived from the cap, when the latter is obtained in a single piece, in particular by molding.
- a container for conditioning a liquid 1 is spontaneously reversible deformation, to allow distribution of the liquid 1 from a manual compression exerted by a user of its wall 2 and a spontaneous return to its initial shape by admission of 'air.
- This container provides a capacity 15 for storing the liquid 1, and is equipped with a distribution head 3 for the drip liquid.
- This dispensing head 3 mainly consists of a hollow body 4 provided with a nozzle 5, and a removable cap 6 for closing off the nozzle 5.
- An anti-bacterial, partially hydrophilic and partially hydrophobic filter membrane 7, therefore permeable to air but also to liquid, is arranged upstream of the nozzle 5, to protect the liquid against an undesirable introduction of polluting agents possibly present in the ambient air, bacteria in particular.
- the body 4 of the dispensing head 3 houses in its internal recess a microporous pad 8 which is made of a hydrophobic material, in particular of polyethylene, to prevent the passage of the liquid 1 towards the nozzle 5, in the absence of compression. on the wall 2 of the container.
- This microporous pad 8 is placed upstream and at a distance from the membrane 7, so as to provide between itself 8 and the latter 7 an intermediate chamber 9.
- the chamber 9 extends over the entire surface of the tampon so as to constitute a reserve of air which exerts, when the nozzle 5 is closed by the cap 6, a pressure over the entire surface of the tampon 8 preventing the liquid 1 from passing. through the microporous pad 8 when the nozzle 5 is closed by the cap 6. More precisely, the cap 6 obstructs an evacuation of the air out of the container, and more particularly out of the intermediate chamber 9. The air being confined downstream of the microporous pad 8, the latter obstructs the passage of the liquid 1 through it as long as the nozzle 5 is closed by the cap 6. Conversely for delivery of the liquid 1, the microporous pad 8 does not prevent this. delivery as soon as the air can be evacuated out of the container through the nozzle 5.
- the intermediate chamber 9 is used to allow spontaneous regularization the flow of liquid 1 passing through the microporous pad 8, prior to its distribution through the nozzle 5.
- the intermediate chamber 9 extends over the entire surface of the membrane so as to constitute a capacity for collecting the liquid 1 away from the membrane 7 when the pressure on the wall 2 of the container is stopped and thus favoring the drying of the membrane between two deliveries of liquid.
- the body 4 is permanently assembled inside the neck 10 of the container, by force fitting. According to the various variants illustrated on the figure 1 and the figure 2 , this interlocking is achieved either directly by close contact between the outer surfaces of the body 4 and the inner surfaces of the neck 10, as illustrated on figure 1 , or and preferably by means of toroidal rings 11 formed at the periphery of the body 4, as illustrated in FIG. figure 2 . It will be noted in these exemplary embodiments the preferred presence of a centering member 12 formed at the base of the body 4 to facilitate its introduction inside the neck 10 of the container.
- the centering member 12 illustrated for example generally consists of radial junction wings 13 by interlocking the body 4 on the neck 10, the wings 13 defining between them recessed sectors, more particularly visible on the figure 3 .
- the cap 6 comprises a pin 15 penetrating inside the nozzle 5 of the dispensing head and a skirt 16 covering the nozzle.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Ceramic Engineering (AREA)
- Closures For Containers (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Details Of Rigid Or Semi-Rigid Containers (AREA)
Description
L'invention est du domaine du conditionnement et de la distribution de liquides, tels que des solutions pharmaceutiques et notamment des collyres. Elle a pour objet un récipient équipé d'une tête de distribution, qui est organisé pour contenir un liquide en le protégeant du milieu extérieur et pour délivrer ce liquide de manière contrôlée, goutte à goutte notamment.The invention relates to the field of packaging and distribution of liquids, such as pharmaceutical solutions and in particular eye drops. Its object is a container equipped with a dispensing head, which is organized to contain a liquid while protecting it from the external environment and to deliver this liquid in a controlled manner, drop by drop in particular.
On connaît des récipients pour contenir un liquide, qui sont organisés pour préserver ce liquide du milieu extérieur et pour le délivrer de manière contrôlée, goutte à goutte notamment. Les applications de tels récipients sont nombreuses, et une application privilégiée, mais non restrictive quant à la portée de la présente invention, réside dans la conservation et la distribution d'une solution pharmaceutique, collyre notamment.Receptacles are known for containing a liquid, which are organized to preserve this liquid from the external environment and to deliver it in a controlled manner, in particular drop by drop. The applications of such containers are numerous, and a preferred application, but not restrictive as regards the scope of the present invention, lies in the storage and distribution of a pharmaceutical solution, eye drops in particular.
Au regard de la préservation du liquide, celui-ci doit être protégé du milieu extérieur en évitant son contact avec l'air ambiant qui est susceptible de contenir des agents polluants, bactéries notamment. Pour la distribution du liquide, il est commun de conférer au récipient un caractère déformable permettant de réduire sa capacité, au moins temporairement, pour évacuer le liquide qu'il contient. De tels récipients sont plus précisément à paroi souple, pour provoquer une évacuation du liquide à partir d'une compression exercée par l'utilisateur sur cette paroi, et ils sont équipés d'une tête de distribution, pour atteindre les deux objectifs que sont la préservation et la distribution contrôlée du liquide.With regard to the preservation of the liquid, it must be protected from the external environment by avoiding its contact with the ambient air which is likely to contain polluting agents, bacteria in particular. For the distribution of the liquid, it is common to give the container a deformable character making it possible to reduce its capacity, at least temporarily, to evacuate the liquid which it contains. Such containers are more precisely flexible wall, to cause an evacuation of the liquid from a compression exerted by the user on this wall, and they are equipped with a dispensing head, to achieve the two objectives that are the preservation and controlled distribution of liquid.
Cependant, les solutions apportées pour parvenir spécifiquement à l'un et l'autre de ces objectifs sont susceptibles d'être antagonistes, et les efforts des concepteurs dans le domaine portent notamment sur la recherche d'un compromis entre les différentes solutions. Il doit en outre être pris en compte une structure souhaitée simple du récipient, dont le coût d'obtention ne doit pas être rédhibitoire eu égard à son caractère consommable, et dont l'utilisation doit être commode pour l'utilisateur.However, the solutions provided to specifically achieve one and the other of these objectives are likely to be antagonistic, and the efforts of designers in the field relate in particular to the search for a compromise between the various solutions. It must also be taken into account a simple desired structure of the container, the cost of obtaining must not be prohibitive given with regard to its consumable nature, and the use of which must be convenient for the user.
On notera à ce stade de la description qu'il est commun dans le domaine d'utiliser une membrane filtrante pour empêcher le passage d'agents polluants depuis l'extérieur du récipient vers le liquide qu'il contient. Cette membrane, placée au voisinage d'une buse que comporte la tête de distribution pour l'évacuation du liquide hors du récipient, autorise un passage du liquide à son travers sous l'effet de la compression exercée dans le récipient par déformation de la paroi.It will be noted at this stage of the description that it is common in the field to use a filter membrane to prevent the passage of polluting agents from the outside of the container to the liquid it contains. This membrane, placed in the vicinity of a nozzle which the dispensing head comprises for discharging the liquid from the container, allows liquid to pass through it under the effect of the compression exerted in the container by deformation of the wall. .
Selon une première approche, il a été proposé de conférer au récipient un caractère déformable irréversible, ou quasiment irréversible. Une paroi interne du récipient délimitant la capacité de réception du liquide est organisée en soufflet, et est enveloppée d'une gaine extérieure. Ce récipient contient en outre une membrane filtrante qui présente un caractère imperméable à l'air, pour interdire une admission d'air extérieur vers le liquide contenu dans le récipient, sous l'effet d'un retrait de liquide délivré. On pourra par exemple se reporter aux documents de brevets
Se pose le problème à résoudre de la délivrance contrôlée du liquide. Selon le document
Selon une deuxième approche, il a été proposé de conférer au récipient une faculté de déformation réversible. On pourra notamment se reporter au document
Il en ressort que les concepteurs du domaine restent confrontés à un compromis à trouver entre simplicité de la tête de distribution, préservation du liquide vis-à-vis d'agents polluants éventuellement présents dans l'air ambiant, faculté de dosage du liquide délivré, et utilisation optimale de tout le liquide contenu dans le réservoir.It emerges that the designers in the field are still faced with a compromise to be found between simplicity of the dispensing head, preservation of the liquid vis-à-vis polluting agents possibly present in the ambient air, ability to dose the liquid delivered, and optimal use of all the liquid in the tank.
La présente invention s'inscrit dans cette recherche de compromis, et vise à proposer un récipient pour le conditionnement d'un liquide à distribuer goutte à goutte qui offre une solution répondant à un tel compromis. L'invention s'inscrit plus spécifiquement dans le conditionnement d'un liquide sensible, tel qu'une solution pharmaceutique, biologique ou analogue, collyre notamment.The present invention is part of this search for a compromise, and aims to provide a container for packaging a liquid to be distributed dropwise which offers a solution responding to such a compromise. The invention relates more specifically to the packaging of a sensitive liquid, such as a pharmaceutical, biological or similar solution, eye drops in particular.
La démarche inventive de la présente invention a consisté dans sa généralité, à choisir en premier lieu un récipient du type comportant un réservoir à paroi à déformation élastiquement réversible par admission d'air à l'intérieur du récipient. Ce choix vise à permettre une délivrance du liquide sous l'effet d'une pression exercée contre cette paroi, et à autoriser un retour spontané du récipient à sa conformation initiale après délivrance d'une dose de liquide. Un tel réservoir à paroi à déformation réversible présente déjà en lui-même l'avantage d'une grande simplicité de fabrication, par rapport aux réservoirs à déformation irréversible de l'art antérieur, qui nécessitent un nombre de pièces et d'opérations d'assemblage important.The inventive approach of the present invention has generally consisted in choosing first of all a container of the type comprising a reservoir with a wall with elastically reversible deformation by admission of air inside the container. This choice aims to allow delivery of the liquid under the effect of a pressure exerted against this wall, and to allow a spontaneous return of the container to its initial configuration after delivery of a dose of liquid. Such a reservoir with a reversible deformation wall already presents in itself the advantage of a great simplicity of manufacture, compared to irreversible deformation tanks of the prior art, which require a large number of parts and assembly operations.
Dans sa généralité, on reconnaîtra un tel récipient selon la présente invention en ce qu'il est équipé d'une tête de distribution comprenant un corps évidé qui est muni d'une buse de délivrance du liquide et qui contient un tampon microporeux en matière hydrophobe placé en aval du réservoir en travers du corps de la tête de distribution. Ledit corps est assemblé de manière irréversible à l'intérieur du col du récipient.In general, such a container according to the present invention will be recognized in that it is equipped with a dispensing head comprising a hollow body which is provided with a nozzle for delivering the liquid and which contains a microporous pad of hydrophobic material. placed downstream of the reservoir across the body of the dispensing head. Said body is assembled irreversibly inside the neck of the container.
Par ailleurs, il est proposé d'équiper le récipient d'un capuchon amovible d'obturation étanche de la buse qui, associé audit tampon microporeux en matière hydrophobe, fait obstacle à l'écoulement spontané du liquide hors de la capacité du récipient réservée à son stockage vers la buse. Ces dispositions sont telles que le passage spontané du liquide à travers le tampon microporeux hydrophobe est interdit lorsque le capuchon obture de manière étanche la buse, et cela pendant toute la durée d'utilisation du récipient. Inversement, le libre écoulement du liquide hors de la capacité du récipient réservée à son stockage, à travers le tampon microporeux hydrophobe, est autorisé lorsque la buse est dégagée, en vue de la délivrance souhaitée d'une dose de liquide par pression exercée contre la paroi du récipient. En outre, le passage de l'air est autorisé par aspiration à travers le tampon microporeux hydrophobe vers la capacité de stockage après délivrance d'une dose de liquide, cette aspiration étant provoquée par le retour élastique de la paroi du récipient à sa conformation initiale, retour par lequel le récipient reprend sa forme initiale nonobstant un retrait d'une dose de liquide.Furthermore, it is proposed to equip the receptacle with a removable cap for sealing the nozzle which, associated with said microporous pad of hydrophobic material, obstructs the spontaneous flow of the liquid out of the capacity of the receptacle reserved for its storage to the nozzle. These arrangements are such that the spontaneous passage of the liquid through the hydrophobic microporous pad is prohibited when the cap tightly closes the nozzle, and this throughout the duration of use of the container. Conversely, the free flow of the liquid out of the capacity of the container reserved for its storage, through the hydrophobic microporous pad, is authorized when the nozzle is released, with a view to the desired delivery of a dose of liquid by pressure exerted against the nozzle. container wall. In addition, the passage of air is allowed by suction through the hydrophobic microporous pad towards the storage capacity after delivery of a dose of liquid, this suction being caused by the elastic return of the wall of the container to its initial conformation. , return by which the container returns to its initial shape notwithstanding a withdrawal of a dose of liquid.
On notera que le tampon microporeux est de préférence réalisé en polyéthylène, ou matériau analogue, qui lui confère un caractère hydrophobe de sorte qu'il ne soit pas mouillable, son caractère microporeux autorisant néanmoins le passage du liquide à son travers à condition que le différentiel de pression, induit par la pression exercée par l'utilisateur, soit suffisant.It will be noted that the microporous pad is preferably made of polyethylene, or similar material, which gives it a hydrophobic character so that it is not wettable, its microporous character nevertheless allowing the passage of the liquid through it, provided that the differential pressure, induced by the pressure exerted by the user, is sufficient.
Une telle configuration du récipient, et plus particulièrement la combinaison entre le réservoir à déformation réversible, le tampon microporeux et le capuchon d'obturation étanche, est tout à fait avantageuse. En effet, lorsque le capuchon est remis en position d'obturation étanche de la buse, après l'aspiration d'air consécutive à la délivrance d'une dose de liquide et le retour élastique de la paroi du récipient à sa conformation initiale, il se crée une différence de pression entre les parties en amont et en aval du tampon à travers lequel il se crée une perte de charge. Cette différence de pression empêche le liquide contenu dans le récipient de passer à travers le tampon, même si on presse accidentellement sur la paroi du récipient, et elle assure l'étanchéité du flacon, tout en protégeant le liquide qu'il contient des contaminations extérieures. De plus, une telle configuration évite toute stagnation de liquide en aval du tampon, puisque le liquide non expulsé est réaspiré vers la capacité du récipient.Such a configuration of the container, and more particularly the combination between the reversible deformation reservoir, the microporous pad and the tight sealing cap, is quite advantageous. Indeed, when the cap is returned to the sealed position of the nozzle, after the suction of air following the delivery of a dose of liquid and the elastic return of the wall of the container to its initial configuration, it a pressure difference is created between the parts upstream and downstream of the buffer through which a pressure drop is created. This pressure difference prevents the liquid in the container from passing through the pad, even if you accidentally press on the container wall, and it seals the bottle, while protecting the liquid it contains from external contamination. . In addition, such a configuration avoids any stagnation of liquid downstream of the pad, since the non-expelled liquid is sucked back into the capacity of the container.
Le récipient répond avantageusement à un objectif de l'invention, qui est d'assurer une utilisation optimale de tout le contenu du réservoir, et cela de deux façons différentes. D'une part, grâce à sa paroi à déformation élastiquement réversible, le récipient conserve une capacité d'expulsion du liquide intacte jusqu'à la dernière goutte de liquide. En effet, parce que de l'air est aspiré dans le récipient en remplacement de chaque dose de liquide expulsé, la pression d'expulsion disponible dans le flacon est toujours la même tout au long de l'utilisation, et ce jusqu'à la distribution de la dernière goutte. D'autre part, comme il a été exposé précédemment, il ne subsiste en aval du tampon aucune goutte de liquide susceptible d'être contaminée par des agents extérieurs, et qui devrait être éliminée avant toute nouvelle distribution d'une dose propre.The container advantageously meets an objective of the invention, which is to ensure optimum use of all the contents of the reservoir, and this in two different ways. On the one hand, thanks to its elastically reversible deformation wall, the container retains an intact liquid expulsion capacity until the last drop of liquid. In fact, because air is drawn into the container to replace each dose of liquid expelled, the expulsion pressure available in the bottle is always the same throughout use, until the distribution of the last drop. On the other hand, as explained above, there remains downstream of the tampon no drop of liquid liable to be contaminated by external agents, and which should be eliminated before any new distribution of a clean dose.
En outre, le tampon microporeux, à travers lequel se crée une perte de charge, joue un rôle de régulateur de flux, qui favorise la distribution contrôlée de doses de liquide. De plus, il empêche que le liquide contenu dans le flacon s'écoule lorsque le bouchon est ôté, et ce même lorsque le flacon est en position retournée, la tête de distribution étant dirigée vers le bas, tant qu'aucune pression n'est exercée sur la paroi du récipient.In addition, the microporous pad, through which a pressure drop is created, acts as a flow regulator, which promotes the controlled distribution of doses of liquid. In addition, it prevents the liquid contained in the bottle from flowing when the cap is removed, even when the bottle is in the inverted position, the dispensing head being directed downwards, as long as no pressure is exerted on the wall of the container.
Dans le cadre d'une application du récipient à un liquide sensible, solution pharmaceutique notamment, la tête de distribution est préférentiellement équipée d'une membrane filtrante destinée à protéger le liquide d'une admission d'agents polluants présents dans l'air ambiant, bactéries notamment. Suivant l'invention, on choisit alors une membrane au moins en partie hydrophile et au moins en partie hydrophobe, pour autoriser alternativement le passage du liquide et de l'air à son travers, et que l'on dispose dans la tête de distribution en amont de la buse, entre celle-ci et le tampon. Le caractère partiellement hydrophile de la membrane permet de laisser passer le liquide à son travers sous l'effet de la compression exercée dans le récipient par déformation de la paroi, alors que son caractère partiellement hydrophobe autorise une entrée de l'air extérieur dans le récipient, quand ce dernier reprend élastiquement sa forme initiale après chaque compression exercée par l'utilisateur.In the context of an application of the container to a sensitive liquid, in particular a pharmaceutical solution, the dispensing head is preferably equipped with a filter membrane intended to protect the liquid from an admission of polluting agents present in the ambient air, bacteria in particular. According to the invention, a membrane is then chosen which is at least partly hydrophilic and at least partly hydrophobic, to allow the passage of liquid and air alternately through it, and which is placed in the distribution head in upstream of the nozzle, between it and the buffer. The partially hydrophilic nature of the membrane allows the liquid to pass through it under the effect of the compression exerted in the container by deformation of the wall, while its partially hydrophobic nature allows outside air to enter the container. , when the latter resumes its initial shape elastically after each compression exerted by the user.
La membrane constitue en outre avantageusement une perte de charge supplémentaire, qui assure, en combinaison avec le tampon microporeux hydrophobe, qu'aucune fuite de liquide hors du récipient ne se produise tant que l'on ne comprime pas la paroi du récipient.The membrane also advantageously constitutes an additional pressure drop, which ensures, in combination with the hydrophobic microporous pad, that no liquid leakage out of the container occurs until the wall of the container is compressed.
Afin de favoriser le passage de l'air à travers la membrane, l'invention prévoit alors qu'il soit possible de maintenir cette membrane sèche entre deux délivrances de liquide, quand le récipient est en position reposée sur sa base, grâce à la présence d'une chambre intercalaire ménagée en interposition entre le tampon microporeux et la membrane. Une telle chambre intercalaire peut aussi être mise à profit pour constituer une chambre de régularisation de la délivrance du liquide. A cet effet, on peut avantageusement lui donner un volume suffisant pour collecter au moins une goutte de liquide à distribuer lors d'une opération de délivrance du liquide pour le faire sortir goutte à goutte de la tête de distribution.In order to promote the passage of air through the membrane, the invention then provides that it is possible to keep this dry membrane between two liquid deliveries, when the container is in the resting position on its base, thanks to the presence an intermediate chamber arranged interposed between the microporous pad and the membrane. Such an intermediate chamber can also be used to constitute a chamber for regulating the delivery of the liquid. To this end, it can advantageously be given a volume sufficient to collect at least one drop of liquid to be dispensed during an operation for delivering the liquid to make it drop dropwise from the dispensing head.
Le volume de la chambre intercalaire selon l'invention, constitue en outre une réserve d'air qui, quand la buse est obturée par le capuchon, conserve une pression qui tend à empêcher le liquide de passer à travers le tampon microporeux. On notera qu'en association avec la chambre intercalaire, le caractère hydrophobe du tampon microporeux favorise un rôle d'obstacle s'opposant au passage du liquide à son travers.The volume of the intermediate chamber according to the invention also constitutes a reserve of air which, when the nozzle is closed by the cap, maintains a pressure which tends to prevent the liquid from passing through the microporous pad. It will be noted that in association with the intercalary chamber, the character hydrophobic microporous pad promotes a role of obstacle opposing the passage of liquid through it.
La chambre intercalaire selon l'invention, constitue en outre une capacité pour accueillir le liquide n'ayant pas encore traversé la membrane quand on cesse d'exercer une pression sur la paroi du récipient. Pour cela, il est avantageux de s'assurer que la chambre intercalaire s'étende sur toute la surface de la membrane et qu'elle soit située à une distance axiale d'elle suffisante pour favoriser l'assèchement de la membrane dès lors que la pression exercée sur la paroi du récipient cesse après une délivrance de liquide, et que ce récipient est ramené dans sa position de repos, en appui sur sa base et la tête de distribution en haut. Il en résulte que tout reliquat de liquide qui, n'ayant pas été expulsé, reste contenu dans la chambre intercalaire, ne perdure pas à mouiller la membrane par capillarité. On notera que le caractère hydrophobe du tampon microporeux favorise aussi l'assèchement de la membrane.The intermediate chamber according to the invention also constitutes a capacity for receiving the liquid which has not yet passed through the membrane when pressure is ceased to be exerted on the wall of the container. For this, it is advantageous to ensure that the intermediate chamber extends over the entire surface of the membrane and that it is located at an axial distance from it sufficient to promote drying of the membrane as soon as the pressure exerted on the wall of the container ceases after delivery of liquid, and this container is returned to its rest position, resting on its base and the dispensing head at the top. As a result, any remaining liquid which, not having been expelled, remains contained in the intermediate chamber, does not continue to wet the membrane by capillary action. It will be noted that the hydrophobic nature of the microporous pad also promotes drying of the membrane.
Par ses différentes caractéristiques, telles qu'elles ont été évoquées ci-avant et qu'elles seront plus complètement définies et décrites ci-après, l'invention a l'avantage, dans la pratique industrielle, de s'affranchir des systèmes complexes de fermeture dynamique que l'on utilisait antérieurement. Grâce aux dispositions prévues par l'invention, il n'est besoin ni d'un opercule ou autre cloison déchirable, ni d'un clapet d'autre forme, ni d'une procédure d'ouverture du flacon par translation ou rotation de la tête de distribution par rapport au récipient réservoir de liquide à distribuer à goutte à goutte.By virtue of its various characteristics, as they were mentioned above and which will be more fully defined and described below, the invention has the advantage, in industrial practice, of being free from complex control systems. dynamic closure that was used previously. Thanks to the arrangements provided for by the invention, there is no need for a cap or other tear-off partition, or a valve of another shape, or a procedure for opening the bottle by translation or rotation of the bottle. distribution head with respect to the reservoir container for liquid to be distributed dropwise.
On relèvera en particulier la combinaison avantageuse de la présence du tampon microporeux à caractère hydrophobe, de celle de la membrane filtrante, et de celle de la chambre intercalaire entre eux, qui confèrent conjointement à la tête de distribution à la fois une fonction de régularisation du flux de liquide lors de l'expulsion de ce dernier et une fonction d'obturation et d'assèchement de la membrane en combinaison avec la pression de l'air retenu dans la chambre intercalaire en raison de la fermeture étanche du capuchon sur la tête de distribution.In particular, the advantageous combination of the presence of the hydrophobic microporous pad, that of the filtering membrane, and that of the intermediate chamber between them, which jointly confer on the dispensing head both a regulating function of the flow of liquid during the expulsion of the latter and a function of sealing and drying the membrane in combination with the pressure of the air retained in the intermediate chamber due to the tight closure of the cap on the head of distribution.
Un tampon microporeux tout à fait approprié dans le cadre de l'invention présente, pour le passage du liquide dans la direction longitudinale, des microcanaux dont le diamètre de pores moyen est compris entre 0,3 et 10 microns.A microporous pad which is quite suitable in the context of the invention has, for the passage of the liquid in the longitudinal direction, microchannels whose average pore diameter is between 0.3 and 10 microns.
Une telle fourchette de valeurs est notamment particulièrement appropriée dans le domaine d'application privilégié de l'invention, qui est la conservation et la distribution d'une solution pharmaceutique, notamment de collyre.Such a range of values is particularly suitable in the privileged field of application of the invention, which is the storage and distribution of a pharmaceutical solution, in particular of eye drops.
En outre, elle assure que le tampon produira une perte de charge suffisante pour isoler la membrane du liquide contenu dans le récipient avant la première utilisation. On évite de ce fait avantageusement que la membrane se dégrade au contact du liquide lors de la phase de stockage du récipient avant la première utilisation.In addition, it ensures that the tampon will produce sufficient pressure drop to isolate the membrane from the liquid in the container before first use. This advantageously prevents the membrane from degrading on contact with the liquid during the storage phase of the container before the first use.
En outre, il est tout à fait avantageux dans le cadre de l'invention d'associer un tel tampon microporeux avec une membrane partiellement hydrophile et partiellement hydrophobe dont le diamètre de pores est inférieur à celui du tampon, notamment compris entre 0,1 et 0,2 microns. On obtient de ce fait notamment des propriétés d'étanchéité et de régulation de flux de la tête de distribution améliorées.In addition, it is quite advantageous in the context of the invention to combine such a microporous pad with a partially hydrophilic and partially hydrophobic membrane, the pore diameter of which is smaller than that of the pad, in particular between 0.1 and 0.2 microns. Improved sealing and flow regulation properties of the dispensing head are thereby obtained in particular.
La membrane peut être réalisée en un matériau polymère, à base par exemple de résine de polyamide ou de polyéther sulfone, qui lui donne un caractère hydrophile. Elle est alors rendue partiellement hydrophobe par modification de sa structure sur une partie de sa surface. Une telle modification peut être réalisée d'une façon classique en elle-même, par exemple par greffage en présence d'un initiateur de réactions radicalaires. Le traitement est avantageusement réalisé de façon à rendre la membrane hydrophobe sur une bande médiane occupant 20 à 50 % de sa surface qui est mouillée lors de l'expulsion du liquide.The membrane may be made of a polymer material, based for example on a polyamide resin or on a polyether sulfone, which gives it a hydrophilic character. It is then made partially hydrophobic by modifying its structure over part of its surface. Such a modification can be carried out in a manner which is conventional in itself, for example by grafting in the presence of an initiator of radical reactions. The treatment is advantageously carried out so as to make the membrane hydrophobic on a middle band occupying 20 to 50% of its surface which is wetted during the expulsion of the liquid.
Préférentiellement, le corps est assemblé à l'intérieur du col par emboîtement en contact étroit.Preferably, the body is assembled inside the neck by interlocking in close contact.
Le corps est de préférence élastiquement déformable pour son introduction en force à l'intérieur du col du récipient, un organe de centrage étant préférentiellement ménagé à la base du corps pour faciliter une telle introduction en force. Cet organe de centrage est de préférence constitué d'ailes radiales de jonction par emboîtement du corps de la tête de distribution sur le col du récipient, les ailes délimitant entre elles des secteurs évidés.The body is preferably elastically deformable for its introduction by force inside the neck of the container, a centering member preferably being provided at the base of the body to facilitate such an introduction in strength. This centering member preferably consists of radial junction wings by interlocking the body of the dispensing head on the neck of the container, the wings delimiting hollow sectors between them.
Pour favoriser encore l'étanchéité du récipient et l'introduction en contact étroit du corps à l'intérieur du col du récipient, la surface extérieure du corps de la tête de distribution est avantageusement équipée d'un jonc périphérique issu dudit corps avec lequel il constitue un ensemble monobloc, ce jonc étant de préférence en pluralité et axialement répété sur le corps.To further promote the sealing of the container and the introduction into close contact of the body inside the neck of the container, the outer surface of the body of the dispensing head is advantageously equipped with a peripheral ring coming from said body with which it constitutes a one-piece assembly, this ring preferably being in plurality and axially repeated on the body.
On notera que le corps est avantageusement obtenu par moulage, dans des conditions telles qu'un jonc, issu du plan de joint, soit radial à son axe général d'extension, et notamment le cas échéant parallèle au jonc périphérique précité. Ce jonc résultant du plan de joint est plus particulièrement situé à l'extrémité distale du corps, à la limite de jonction de l'organe de centrage, pour favoriser au mieux l'étanchéité entre la tête de distribution et le récipient.It will be noted that the body is advantageously obtained by molding, under conditions such as a ring, coming from the joint plane, is radial to its general axis of extension, and in particular where appropriate parallel to the aforementioned peripheral ring. This ring resulting from the joint plane is more particularly located at the distal end of the body, at the junction limit of the centering member, in order to best promote the seal between the dispensing head and the container.
Le capuchon amovible quant à lui est rapporté préférentiellement sur le récipient par vissage pour favoriser le serrage du capuchon sur la tête de distribution, et donc l'étanchéité entre ces organes.The removable cap for its part is preferably attached to the container by screwing to promote the tightening of the cap on the dispensing head, and therefore the seal between these members.
A cet effet, le capuchon comporte avantageusement une combinaison d'organes d'étanchéité associant un picot pénétrant à l'intérieur de la buse de la tête de distribution et une jupe coiffant cette buse. Le picot et la jupe sont avantageusement issus du capuchon, lors de l'obtention de ce dernier d'une seule pièce, par moulage notamment.To this end, the cap advantageously comprises a combination of sealing members associating a pin penetrating inside the nozzle of the dispensing head and a skirt covering this nozzle. The pin and the skirt are advantageously derived from the cap, when the latter is obtained in a single piece, in particular by molding.
La présente invention sera mieux comprise à la lecture de la description qui va en être faite en relation avec les figures de la planche annexée, dans laquelle:
- La
figure 1 et lafigure 2 sont des schémas en coupe axiale qui illustrent un récipient pour le conditionnement d'un liquide selon des variantes respectives de réalisation de la présente invention. - La
figure 3 est une vue en coupe du récipient illustré sur lafigure 2 , prise radialement dans la zone d'un organe de centrage que celui-ci comporte.
- The
figure 1 and thefigure 2 are diagrams in axial section which illustrate a container for packaging a liquid according to respective variant embodiments of the present invention. - The
figure 3 is a sectional view of the container illustrated infigure 2 , taken radially in the zone of a centering member which the latter comprises.
Sur les
Le corps 4 de la tête de distribution 3 loge dans son évidement intérieur un tampon microporeux 8 qui est réalisé en une matière hydrophobe, notamment en polyéthylène, pour interdire le passage du liquide 1 vers la buse 5, en l'absence d'une compression sur la paroi 2 du récipient. Ce tampon microporeux 8 est disposé en amont et à distance de la membrane 7, de manière à ménager entre lui-même 8 et cette dernière 7 une chambre intercalaire 9.The
La chambre 9 s'étend sur toute la surface du tampon de manière à constituer une réserve d'air qui exerce, quand la buse 5 est obturée par le capuchon 6, une pression sur toute la surface du tampon 8 empêchant le liquide 1 de passer à travers le tampon microporeux 8 lorsque la buse 5 est obturée par le capuchon 6. Plus précisément, le capuchon 6 fait obstacle à une évacuation de l'air hors du récipient, et plus particulièrement hors de la chambre intercalaire 9. L'air étant confiné en aval du tampon microporeux 8, ce dernier fait obstacle au passage du liquide 1 à son travers tant que la buse 5 est obturée par le capuchon 6. Inversement pour une délivrance du liquide 1, le tampon microporeux 8 ne fait pas obstacle à cette délivrance dès lors que l'air peut être évacué hors du récipient à travers la buse 5. La chambre intercalaire 9 est mise à profit pour permettre une régularisation spontanée du flux du liquide 1 traversant le tampon microporeux 8, préalablement à sa distribution à travers la buse 5.The
La chambre intercalaire 9 s'étend sur toute la surface de la membrane de manière à constituer une capacité pour recueillir le liquide 1 à l'écart de la membrane 7 quand on cesse d'exercer une pression sur la paroi 2 du récipient et favoriser ainsi l'assèchement de la membrane entre deux délivrances de liquide.The
Le corps 4 est assemblé à demeure à l'intérieur du col 10 du récipient, par emboîtement en force. Selon les diverses variantes illustrées sur la
On relèvera enfin sur les variantes illustrées l'assemblage par vissage du capuchon 6 sur le col 10 du récipient, par l'intermédiaire de reliefs 14 coopérants. Pour faciliter le vissage du capuchon 6 sur le récipient et conforter l'étanchéité entre l'un et l'autre, le capuchon 6 comporte un picot 15 pénétrant à l'intérieur de la buse 5 de la tête de distribution et une jupe 16 coiffant la buse.Finally, in the illustrated variants, we will note the assembly by screwing the
Claims (13)
- Container for the packaging of a liquid to be dispensed drop by drop, comprising- a reservoir with an elastically deformable wall (2) that is reversible by the admission of air inside the container in order to deliver the liquid (1) under the effect of pressure exerted against this wall (2) and to allow spontaneous return of the container to its initial conformation after delivery of a dose of liquid (1),- a base on which the container can stand in a position of rest between two deliveries of liquid;- a dispensing head (3) comprising a hollowed-out body (4) that is provided with a nozzle (5) for delivering liquid (1) and an anti-bacterial filtering membrane (7) that is disposed upstream of the nozzle,- the container being configured such that when it rests on its base the dispensing head is uppermost; andthe container being characterized in that it comprises a hydrophobic microporous pad (8) that is placed downstream of the reservoir inside the body (4), said body (4) being assembled irreversibly inside a neck (10) of the container, said filtering membrane (7) being disposed between the nozzle and the pad (8), the membrane (7) being partially hydrophilic for allowing the liquid to pass through it under the effect of the overpressure created in the container by pressure of its wall, and partially hydrophobic to allow the passage of air through it under the effect of the negative pressure created in the container by releasing the pressure exerted on its wall, and in that it comprises an intermediate chamber (9) for regularising the delivery of the liquid, which is provided interposed between the microporous pad (8) and the membrane (7), said intermediate chamber extending over the entire surface of the membrane and at a sufficient axial distance to accommodate the liquid that has not yet passed through the membrane when pressure ceases to be exerted on the wall of the container and thus to assist the drying of the membrane between two deliveries of liquid, such that any residue of liquid, which, having not been expelled does not succeed in wetting the membrane by capillarity when the container is placed in its position of rest standing on its base.
- Container for the packaging of a liquid to be dispensed drop by drop according to claim 1, characterised in that the microporous pad (8) is produced from polyethylene in order to confer on it its hydrophobic character, its microporous character nevertheless allowing passage of the liquid through it under the effect of a pressure differential caused by a pressure exerted by a user against the wall of the container.
- Container for the packaging of a liquid to be dispensed drop by drop according to claim 1 or 2, characterised in that the microporous pad (8) has microchannels, the mean pore diameter of which is between 0.3 and 10 microns.
- Container for the packaging of a liquid to be dispensed drop by drop according to one of the preceding claims, wherein the filtering membrane (7) has pores of a diameter smaller than the diameter of the pores of the microporous pad and comprised between 0.1 and 0.2 microns.
- Container for the packaging of a liquid to be dispensed drop by drop according to any of the preceding claims, characterised in that the body (4) is assembled inside the neck (10) of the container by fitting in close contact.
- Container for the packaging of a liquid to be dispensed drop by drop according to claim 5, characterised in that the body (4) is elastically deformable for forcible introduction thereof inside the neck (10) of the container, a centring member (12) being provided at the base of the body (4) to facilitate such forcible introduction.
- Container for the packaging of a liquid to be dispensed drop by drop according to claim 6, characterised in that the centring member (12) consists of radial fins (13) for joining the body (4) of the dispensing head to the neck (10) of the container by fitting together, the fins (13) delimiting hollowed-out sectors between them.
- Container for the packaging of a liquid to be dispensed drop by drop according to any of claims 5 to 7, characterised in that the external surface of the body (4) of the dispensing head is equipped with at least one O-ring (11) issuing from said body (4), with which it constitutes a single-piece assembly, optionally a plurality of axially distributed O-rings.
- Container for the packaging of a liquid to be dispensed drop by drop according to any of the preceding claims, characterised in that the body (4) of the dispensing head is obtained by moulding under conditions such that a ring (17), resulting from the moulding parting plane, is situated at the distal end of the body (4) at the junction boundary of the centring member (1), which assists the obtaining of a sealed connection between the dispensing head and the container.
- Container for the packaging of a liquid to be dispensed drop by drop according to any of the preceding claims, further comprising a removable cap (6)for sealed closure of the nozzle (5) .
- Container for the packaging of a liquid to be dispensed drop by drop according to claim 10, characterised in that the removable cap (6) is attached to the container by screwing.
- Container for the packaging of a liquid to be dispensed drop by drop according to claim 11, characterised in that the cap (6) comprises a combination of sealing members associating a spike (15) penetrating inside the nozzle (5) of the dispensing head and a skirt (16) fitting on top of this nozzle (5) .
- Assembly comprising a container for the packaging of a liquid to be dispensed drop by drop according to one of the preceding claims, and a liquid contained in said container, the liquid being a pharmaceutical solution, for example eye drops.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI200532298T SI3412590T1 (en) | 2004-06-24 | 2005-06-24 | Container for packaging a liquid drop dispenser, reversibly deformed by air inlet |
PL18183420T PL3412590T3 (en) | 2004-06-24 | 2005-06-24 | Container for packaging a liquid drop dispenser, reversibly deformed by air inlet |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0407042A FR2872137B1 (en) | 2004-06-24 | 2004-06-24 | CONTAINER FOR THE CONDITIONING OF A LIQUID WITH A DROPPER FLOW DISTRIBUTOR WITH REVERSIBLE DEFORMATION BY AIR INTAKE |
PCT/IB2005/001791 WO2006000897A1 (en) | 2004-06-24 | 2005-06-24 | Container for packaging a liquid to be dispensed in drops reversibly deformed by air input |
EP05756044.3A EP1765513B1 (en) | 2004-06-24 | 2005-06-24 | Container for packaging a liquid to be dispensed in drops reversibly deformed by air input |
Related Parent Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP05756044.3A Division EP1765513B1 (en) | 2004-06-24 | 2005-06-24 | Container for packaging a liquid to be dispensed in drops reversibly deformed by air input |
EP05756044.3A Division-Into EP1765513B1 (en) | 2004-06-24 | 2005-06-24 | Container for packaging a liquid to be dispensed in drops reversibly deformed by air input |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3412590A1 EP3412590A1 (en) | 2018-12-12 |
EP3412590B1 true EP3412590B1 (en) | 2021-08-04 |
Family
ID=34949309
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP18183420.1A Active EP3412590B1 (en) | 2004-06-24 | 2005-06-24 | Container for packaging a liquid drop dispenser, reversibly deformed by air inlet |
EP05756044.3A Active EP1765513B1 (en) | 2004-06-24 | 2005-06-24 | Container for packaging a liquid to be dispensed in drops reversibly deformed by air input |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP05756044.3A Active EP1765513B1 (en) | 2004-06-24 | 2005-06-24 | Container for packaging a liquid to be dispensed in drops reversibly deformed by air input |
Country Status (27)
Country | Link |
---|---|
US (1) | US7971755B2 (en) |
EP (2) | EP3412590B1 (en) |
JP (2) | JP5080972B2 (en) |
KR (1) | KR100919520B1 (en) |
CN (1) | CN100475359C (en) |
AR (1) | AR051064A1 (en) |
BR (1) | BRPI0512387B8 (en) |
CA (1) | CA2572048C (en) |
CY (2) | CY1120837T1 (en) |
DK (2) | DK1765513T3 (en) |
ES (2) | ES2691721T3 (en) |
FR (1) | FR2872137B1 (en) |
HK (1) | HK1104253A1 (en) |
HU (2) | HUE056784T2 (en) |
LT (2) | LT3412590T (en) |
MA (1) | MA28671B1 (en) |
MX (1) | MXPA06014657A (en) |
MY (1) | MY164320A (en) |
NO (1) | NO343517B1 (en) |
PL (2) | PL3412590T3 (en) |
PT (2) | PT3412590T (en) |
RU (1) | RU2385774C2 (en) |
SI (2) | SI1765513T1 (en) |
TN (1) | TNSN06415A1 (en) |
TR (1) | TR201815132T4 (en) |
WO (1) | WO2006000897A1 (en) |
ZA (1) | ZA200700248B (en) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2897599B1 (en) * | 2006-02-23 | 2010-08-27 | Rexam Pharma | LIQUID CONDITIONING AND DISPENSING ASSEMBLY. |
FR2908043B1 (en) * | 2006-11-03 | 2009-01-23 | Prevor Internat Sarl | PORTABLE INDIVIDUAL DEVICE FOR EYE BATH |
DE102008027146B4 (en) * | 2008-06-02 | 2012-01-19 | Ing. Erich Pfeiffer Gmbh | discharge |
JP5224915B2 (en) * | 2008-06-03 | 2013-07-03 | 大成化工株式会社 | Discharge container with filter |
FR2934572A1 (en) * | 2008-07-31 | 2010-02-05 | Thea Lab | BOTTLE FOR FLASK OF LIQUID CONDITIONING TO DISPENSE DROP GOUTTE. |
FR2937018B1 (en) | 2008-10-15 | 2012-06-01 | Rexam Pharma La Verpilliere | LIQUID DISPENSING DEVICE HAVING A DISPLACABLE SEALING MEMBER UNDER THE EFFECT OF A USER'S PRESSURE |
SE0901365A1 (en) * | 2009-10-22 | 2010-07-27 | Mahbobeh-Taghinejad Sadabadi | dosing device |
FR2952040B1 (en) | 2009-10-29 | 2011-12-30 | Rexam Pharma La Verpilliere | DEVICE FOR DISPENSING LIQUID IN THE FORM OF DROPS |
FR2955842B1 (en) * | 2010-02-04 | 2012-03-16 | Thea Lab | FLUID FOR PACKAGING A LIQUID WITH A DROP-IN DISTRIBUTION HEAD |
FR2963329B1 (en) * | 2010-07-30 | 2013-06-28 | Thea Lab | HEAD FOR DISPENSING A DROP FLUID LIQUID |
FR2974742B1 (en) * | 2011-05-04 | 2013-05-03 | Rexam Healthcare La Verpillier | LIQUID DISPENSING DEVICE WITH AIR CHANNEL CHANNEL |
EP2739402B1 (en) | 2011-08-01 | 2015-07-22 | Colgate-Palmolive Company | Dispensing container with enhanced appearance |
FR2994162B1 (en) * | 2012-08-06 | 2014-09-05 | Thea Lab | LIQUID DISPENSING HEAD, IN PARTICULAR FOR A BOTTLE OF A LIQUID DISPENSING FLUID |
US9096352B2 (en) | 2012-12-03 | 2015-08-04 | RLM Group Ltd. | Enhanced dispensing and dosaging techniques for fluid containers |
US9296525B2 (en) | 2012-12-03 | 2016-03-29 | RLM Group Ltd. | Enhanced dispensing and dosaging techniques for fluid containers |
US20160330969A1 (en) * | 2013-10-23 | 2016-11-17 | John F. O'Connell, JR. | Antimicrobial compositions and articles |
CN104097843B (en) * | 2014-07-28 | 2016-08-24 | 武汉五景药业有限公司 | A kind of aseptic filtration type bottle cap |
EP3277233B1 (en) * | 2015-03-31 | 2024-07-03 | Laboratoires THEA | Device for dispensing liquid from a sterile packaging bottle with bifunctional membrane |
FR3035080B1 (en) * | 2015-04-17 | 2019-08-09 | Centre Hospitalier Universitaire D'amiens-Picardie | CLOSURE DEVICE FOR PERMITTING A SAMPLE OF A PACKAGING ASSEMBLY COMPOSITION COMPRISING SUCH A CLOGGING DEVICE, METHODS FOR COLLECTING AND PACKAGING |
CN105197383A (en) * | 2015-10-17 | 2015-12-30 | 李红彪 | External hung absorbable and extrudable nozzle |
WO2017078043A1 (en) * | 2015-11-05 | 2017-05-11 | 栄研化学株式会社 | Discharge member with filter |
WO2017138615A1 (en) | 2016-02-12 | 2017-08-17 | 株式会社徳重 | Portable container |
EP3323753B1 (en) * | 2016-11-17 | 2019-08-07 | Aptar Radolfzell GmbH | Discharge head and liquid dispenser with such a discharge head |
US10343183B2 (en) * | 2016-12-21 | 2019-07-09 | Stoneridge Kitchen & Bath Llc | Glue gun |
KR20190033359A (en) * | 2017-09-21 | 2019-03-29 | 주식회사 아이팩 | A discharge device for discharging the liquid content in the tube container in a droplet form |
US10788263B1 (en) * | 2018-02-17 | 2020-09-29 | Clearman Labs, LLC | Drying, space-saving soap bar container methods, systems, and devices |
CN108357805B (en) * | 2018-03-27 | 2023-05-12 | 郭思治 | Use method of eyedrop bottle capable of adjusting dosage |
CN208264912U (en) * | 2018-03-28 | 2018-12-21 | 深圳市通产丽星股份有限公司 | A kind of drop hose |
FR3080843B1 (en) * | 2018-05-07 | 2020-05-29 | Horus Pharma | DEVICE FOR PACKAGING AND DISPENSING A PRODUCT HAVING AN EXTERNALLY CLEAN END END DOSER |
FR3080844B1 (en) * | 2018-05-07 | 2020-06-05 | Horus Pharma | PACKAGING AND DISPENSING DEVICE OF A PRODUCT WITH BOTTLE AND METERING CAP WITH FILTER |
GB201809627D0 (en) * | 2018-06-12 | 2018-07-25 | Biorelevant Com Ltd | Methods for preparing buffer solutions suitable for in vitro drug dissolution testing, drug solubility testing and/or drug profiling |
CN109620720A (en) * | 2018-12-29 | 2019-04-16 | 上海千盈实业有限公司 | A kind of transfusion package lid and its production method |
US11618612B2 (en) | 2019-02-27 | 2023-04-04 | Container Packaging Systems, LLC | Vented pour spout |
US10723526B1 (en) * | 2019-03-29 | 2020-07-28 | Chubby Gorilla, Inc. | Bottle and cap arrangement |
CN112427208B (en) * | 2019-08-16 | 2021-11-26 | 江苏长实基业电气科技有限公司 | Coagulation device |
JP6976469B1 (en) * | 2021-04-26 | 2021-12-08 | さち子 松山 | Eye drop container |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3149758A (en) * | 1961-11-01 | 1964-09-22 | Millipore Filter Corp | Combination filter and flow divider for gas and liquid |
US3189223A (en) * | 1964-05-18 | 1965-06-15 | Halkey Roberts Corp | Liquid dispensing device |
JPH063808Y2 (en) * | 1985-11-27 | 1994-02-02 | ト−メ−産業株式会社 | Secondary contamination prevention cap for eye drops |
JPS62127063A (en) * | 1985-11-27 | 1987-06-09 | ト−メ−産業株式会社 | Eyedropper container |
US4948505A (en) * | 1986-01-27 | 1990-08-14 | Cuno, Inc. | Quick-change filter cartridge and head therefor |
US5320254A (en) * | 1988-10-07 | 1994-06-14 | Ryder International Corp. | Liquid dispenser nozzle assembly |
FR2638428B1 (en) * | 1988-10-28 | 1990-12-28 | Transphyto Sa | PACKAGING FOR PURIFYING LIQUIDS |
US4938389A (en) | 1988-11-03 | 1990-07-03 | Eye Research Institute Of Retina Foundation | Filter bottle |
US5105993A (en) * | 1989-12-29 | 1992-04-21 | La Haye Laboratories, Inc. | Disposable medical dispenser with a filtering dispenser nozzle |
FR2661401B1 (en) * | 1990-04-27 | 1992-07-24 | Transphyto Sa | PACKAGING PROCESS FOR STORING AND DISPENSING BY PORTIONS OF STERILE LIQUID. |
US5074440A (en) * | 1990-07-16 | 1991-12-24 | Alcon Laboratories, Inc. | Container for dispensing preservative-free preparations |
DE4027539A1 (en) * | 1990-08-31 | 1992-03-05 | Kautex Werke Gmbh | Squeeze bottle with inner bag |
JPH0478161U (en) * | 1990-11-20 | 1992-07-08 | ||
US5238153A (en) * | 1991-02-19 | 1993-08-24 | Pilkington Visioncare Inc. | Dispenser for dispersing sterile solutions |
US5310094A (en) * | 1991-11-15 | 1994-05-10 | Jsp Partners, L.P. | Preservative free sterile fluid dispensing system |
ATE168553T1 (en) * | 1993-06-25 | 1998-08-15 | Alcon Cusi S A | NEW USE OF POLYMERIC MEMBRANES FOR DISPENSING PHARMACEUTICAL SOLUTIONS CONTAINING QUARTERNARY AMMONIUM PRESERVATIVE COMPOUNDS AND CORRESPONDING DOSAGE CONTAINER |
US5490938A (en) * | 1993-12-20 | 1996-02-13 | Biopolymerix, Inc. | Liquid dispenser for sterile solutions |
FR2729924B1 (en) * | 1995-02-01 | 1997-04-11 | Kerplas Snc | PRODUCT DISPENSING BOTTLE |
US5611464A (en) * | 1995-05-30 | 1997-03-18 | Ciba Geigy Corporation | Container for preserving media in the tip of a solution dispenser |
US5680969A (en) * | 1995-12-18 | 1997-10-28 | Aptargroup, Inc. | Closure with dispensing valve and separate releasable internal shipping seal |
US5676289A (en) * | 1996-04-04 | 1997-10-14 | Aptargroup, Inc. | Valve-controlled dispensing closure with dispersion baffle |
FR2761665B1 (en) * | 1997-04-02 | 1999-06-25 | Sofab | DEVICE FOR DISPENSING AND PACKAGING STERILE LIQUID PRODUCTS |
FR2769595B1 (en) * | 1997-10-10 | 1999-11-19 | Oreal | DISTRIBUTION HEAD WITH IMPROVED AIR INTAKE, AND PACKAGING AND DISTRIBUTION ASSEMBLY PROVIDED WITH SUCH A HEAD |
FR2770495B1 (en) | 1997-11-04 | 1999-12-24 | Transphyto Sa | PACKAGING DEVICE FOR DRIPPING LIQUID |
US7186045B2 (en) * | 2000-02-16 | 2007-03-06 | L'oreal S.A. | Device and method for applying a cosmetic product |
US6290108B1 (en) * | 2000-04-14 | 2001-09-18 | Seaquist Closures Foreign, Inc. | Dispensing system with an internal releasable shipping seal and an extended tip containing a pressure openable valve |
JP4580524B2 (en) * | 2000-09-12 | 2010-11-17 | 株式会社日本点眼薬研究所 | Discharge container with filter |
FR2816600B1 (en) * | 2000-11-13 | 2003-03-21 | Michel Faurie | DISPENSING DEVICE FOR DROP FLUID LIQUIDS |
JP4749572B2 (en) * | 2001-03-13 | 2011-08-17 | 大成化工株式会社 | Dispensing container plug structure |
JP4047617B2 (en) * | 2002-04-04 | 2008-02-13 | ニプロ株式会社 | Chemical container |
US7427355B2 (en) * | 2004-05-14 | 2008-09-23 | Yiu Chau Chau | Water treatment unit for bottle or pitcher |
-
2004
- 2004-06-24 FR FR0407042A patent/FR2872137B1/en not_active Expired - Lifetime
-
2005
- 2005-06-16 AR ARP050102478A patent/AR051064A1/en active IP Right Grant
- 2005-06-23 MY MYPI20052867A patent/MY164320A/en unknown
- 2005-06-24 CN CNB2005800206713A patent/CN100475359C/en active Active
- 2005-06-24 EP EP18183420.1A patent/EP3412590B1/en active Active
- 2005-06-24 SI SI200532232T patent/SI1765513T1/en unknown
- 2005-06-24 ES ES05756044.3T patent/ES2691721T3/en active Active
- 2005-06-24 DK DK05756044.3T patent/DK1765513T3/en active
- 2005-06-24 EP EP05756044.3A patent/EP1765513B1/en active Active
- 2005-06-24 TR TR2018/15132T patent/TR201815132T4/en unknown
- 2005-06-24 ES ES18183420T patent/ES2891874T3/en active Active
- 2005-06-24 LT LTEP18183420.1T patent/LT3412590T/en unknown
- 2005-06-24 HU HUE18183420A patent/HUE056784T2/en unknown
- 2005-06-24 SI SI200532298T patent/SI3412590T1/en unknown
- 2005-06-24 HU HUE05756044A patent/HUE039799T2/en unknown
- 2005-06-24 CA CA2572048A patent/CA2572048C/en active Active
- 2005-06-24 US US11/630,831 patent/US7971755B2/en active Active
- 2005-06-24 DK DK18183420.1T patent/DK3412590T3/en active
- 2005-06-24 BR BRPI0512387A patent/BRPI0512387B8/en active IP Right Grant
- 2005-06-24 KR KR1020077001804A patent/KR100919520B1/en active IP Right Grant
- 2005-06-24 PT PT181834201T patent/PT3412590T/en unknown
- 2005-06-24 LT LTEP05756044.3T patent/LT1765513T/en unknown
- 2005-06-24 RU RU2007101567/11A patent/RU2385774C2/en active
- 2005-06-24 WO PCT/IB2005/001791 patent/WO2006000897A1/en active Application Filing
- 2005-06-24 PL PL18183420T patent/PL3412590T3/en unknown
- 2005-06-24 PT PT05756044T patent/PT1765513T/en unknown
- 2005-06-24 MX MXPA06014657A patent/MXPA06014657A/en active IP Right Grant
- 2005-06-24 JP JP2007517521A patent/JP5080972B2/en active Active
- 2005-06-24 PL PL05756044T patent/PL1765513T3/en unknown
-
2006
- 2006-12-14 TN TNP2006000415A patent/TNSN06415A1/en unknown
- 2006-12-19 MA MA29543A patent/MA28671B1/en unknown
-
2007
- 2007-01-09 ZA ZA200700248A patent/ZA200700248B/en unknown
- 2007-01-23 NO NO20070474A patent/NO343517B1/en unknown
- 2007-08-20 HK HK07109019.1A patent/HK1104253A1/en unknown
-
2012
- 2012-05-17 JP JP2012113156A patent/JP5307916B2/en active Active
-
2018
- 2018-10-16 CY CY181101052T patent/CY1120837T1/en unknown
-
2021
- 2021-10-20 CY CY20211100912T patent/CY1124636T1/en unknown
Non-Patent Citations (1)
Title |
---|
None * |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP3412590B1 (en) | Container for packaging a liquid drop dispenser, reversibly deformed by air inlet | |
CA2262135C (en) | Packaging and dispenser presentation for a liquid product | |
EP0721573B1 (en) | Metering device for dispensing constant unit doses | |
FR3036384B1 (en) | DISTRIBUTION CAP | |
EP1572375B1 (en) | Manually-actuated metering pump | |
EP3999245A1 (en) | Device for capping a container of a liquid to pasty product, and refill closed by such a device | |
EP3119529B1 (en) | Liquid-dispensing device comprising a protective cap | |
FR2674747A1 (en) | Device for dispensing drops of small volume, in particular for ophthalmological treatment | |
FR3099037A1 (en) | Cosmetic product dispensing pipette comprising an insert for receiving a ball, associated device and method | |
EP1048590A1 (en) | Valve actuating device and assembly comprising such a device | |
FR2749833A1 (en) | CONTAINER FOR PRODUCT DISTRIBUTION | |
FR3076187A1 (en) | COSMETIC PRODUCT PACKAGING SERVICE CAPSULE AND PACKAGING DEVICE THEREFOR | |
EP2879966B1 (en) | Drop dispensing head | |
EP0960829B1 (en) | Valve and storing and distribution assembly comprising such a valve | |
EP3206968B1 (en) | Device for dispensing a cosmetic product in aerosol form, associated assembly and method | |
EP1789338B1 (en) | Cap for a fluid product dispensing head | |
FR2785878A1 (en) | Seal assembly for fluid distribution head comprises elastic element shaped as cup with hole that is covered by fixed cylinder and deforms under effect of product distribution pressure. | |
FR3103396A1 (en) | Liquid container mouthpiece | |
EP1050480B1 (en) | Diaphragm pump comprising a preferential deformation area on at least a part of its periphery, and container incorporating the same | |
EP3125838A1 (en) | Liquid dispensing device | |
WO2022184883A1 (en) | Packaging device with integrated ventilation system | |
EP1375373B1 (en) | Storage and dispensing device for a product | |
FR2862052A1 (en) | Liquid container and dispenser with micro-filtering membranes has liquid absorbing membrane extending along lengthwise axis of flask neck | |
EP1777168A1 (en) | Packaging and dosing device |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION HAS BEEN PUBLISHED |
|
AC | Divisional application: reference to earlier application |
Ref document number: 1765513 Country of ref document: EP Kind code of ref document: P |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: HR LV YU |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: REQUEST FOR EXAMINATION WAS MADE |
|
17P | Request for examination filed |
Effective date: 20190419 |
|
RBV | Designated contracting states (corrected) |
Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
17Q | First examination report despatched |
Effective date: 20190927 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Ref document number: 602005057279 Country of ref document: DE Free format text: PREVIOUS MAIN CLASS: B65D0047180000 Ipc: B65D0001320000 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: B65D 1/32 20060101AFI20201028BHEP Ipc: B65D 47/18 20060101ALI20201028BHEP |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: GRANT OF PATENT IS INTENDED |
|
INTG | Intention to grant announced |
Effective date: 20210126 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE PATENT HAS BEEN GRANTED |
|
AC | Divisional application: reference to earlier application |
Ref document number: 1765513 Country of ref document: EP Kind code of ref document: P |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D Free format text: NOT ENGLISH |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 1416773 Country of ref document: AT Kind code of ref document: T Effective date: 20210815 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602005057279 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D Free format text: LANGUAGE OF EP DOCUMENT: FRENCH |
|
REG | Reference to a national code |
Ref country code: RO Ref legal event code: EPE |
|
REG | Reference to a national code |
Ref country code: PT Ref legal event code: SC4A Ref document number: 3412590 Country of ref document: PT Date of ref document: 20210929 Kind code of ref document: T Free format text: AVAILABILITY OF NATIONAL TRANSLATION Effective date: 20210923 Ref country code: NL Ref legal event code: FP |
|
REG | Reference to a national code |
Ref country code: DK Ref legal event code: T3 Effective date: 20211004 |
|
REG | Reference to a national code |
Ref country code: FI Ref legal event code: FGE |
|
REG | Reference to a national code |
Ref country code: SE Ref legal event code: TRGR |
|
REG | Reference to a national code |
Ref country code: EE Ref legal event code: FG4A Ref document number: E021365 Country of ref document: EE Effective date: 20210930 |
|
REG | Reference to a national code |
Ref country code: GR Ref legal event code: EP Ref document number: 20210402795 Country of ref document: GR Effective date: 20211111 |
|
REG | Reference to a national code |
Ref country code: SK Ref legal event code: T3 Ref document number: E 38440 Country of ref document: SK |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2891874 Country of ref document: ES Kind code of ref document: T3 Effective date: 20220131 |
|
REG | Reference to a national code |
Ref country code: HU Ref legal event code: AG4A Ref document number: E056784 Country of ref document: HU |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 602005057279 Country of ref document: DE |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed |
Effective date: 20220506 |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: UEP Ref document number: 1416773 Country of ref document: AT Kind code of ref document: T Effective date: 20210804 |
|
P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230512 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: RO Payment date: 20230526 Year of fee payment: 19 Ref country code: PT Payment date: 20230517 Year of fee payment: 19 Ref country code: NL Payment date: 20230627 Year of fee payment: 19 Ref country code: MC Payment date: 20230628 Year of fee payment: 19 Ref country code: LT Payment date: 20230523 Year of fee payment: 19 Ref country code: IE Payment date: 20230627 Year of fee payment: 19 Ref country code: FR Payment date: 20230628 Year of fee payment: 19 Ref country code: EE Payment date: 20230523 Year of fee payment: 19 Ref country code: DK Payment date: 20230531 Year of fee payment: 19 Ref country code: DE Payment date: 20230627 Year of fee payment: 19 Ref country code: CZ Payment date: 20230524 Year of fee payment: 19 Ref country code: BG Payment date: 20230530 Year of fee payment: 19 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: TR Payment date: 20230608 Year of fee payment: 19 Ref country code: SK Payment date: 20230518 Year of fee payment: 19 Ref country code: SI Payment date: 20230522 Year of fee payment: 19 Ref country code: SE Payment date: 20230629 Year of fee payment: 19 Ref country code: PL Payment date: 20230530 Year of fee payment: 19 Ref country code: LU Payment date: 20230627 Year of fee payment: 19 Ref country code: IS Payment date: 20230517 Year of fee payment: 19 Ref country code: HU Payment date: 20230525 Year of fee payment: 19 Ref country code: GR Payment date: 20230524 Year of fee payment: 19 Ref country code: FI Payment date: 20230522 Year of fee payment: 19 Ref country code: AT Payment date: 20230627 Year of fee payment: 19 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20230627 Year of fee payment: 19 Ref country code: GB Payment date: 20230711 Year of fee payment: 19 Ref country code: ES Payment date: 20230727 Year of fee payment: 19 Ref country code: CY Payment date: 20230517 Year of fee payment: 19 Ref country code: CH Payment date: 20230702 Year of fee payment: 19 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: BE Payment date: 20230626 Year of fee payment: 19 |