EP3387431A4 - Systeme, verfahren und zusammensetzungen zur verbesserung der spezifität von nukleinsäurehybridisierung - Google Patents

Systeme, verfahren und zusammensetzungen zur verbesserung der spezifität von nukleinsäurehybridisierung Download PDF

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Publication number
EP3387431A4
EP3387431A4 EP16874070.2A EP16874070A EP3387431A4 EP 3387431 A4 EP3387431 A4 EP 3387431A4 EP 16874070 A EP16874070 A EP 16874070A EP 3387431 A4 EP3387431 A4 EP 3387431A4
Authority
EP
European Patent Office
Prior art keywords
specificity
enhancing
compositions
systems
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP16874070.2A
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English (en)
French (fr)
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EP3387431A1 (de
Inventor
Michael Okura
Michael D. Okura
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Individual
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Individual
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Application filed by Individual filed Critical Individual
Publication of EP3387431A1 publication Critical patent/EP3387431A1/de
Publication of EP3387431A4 publication Critical patent/EP3387431A4/de
Withdrawn legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6832Enhancement of hybridisation reaction

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
EP16874070.2A 2015-12-11 2016-12-12 Systeme, verfahren und zusammensetzungen zur verbesserung der spezifität von nukleinsäurehybridisierung Withdrawn EP3387431A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562266143P 2015-12-11 2015-12-11
PCT/US2016/066227 WO2017100792A1 (en) 2015-12-11 2016-12-12 Systems, methods and compositions for enhancing the specificity of nucleic acid hybridization

Publications (2)

Publication Number Publication Date
EP3387431A1 EP3387431A1 (de) 2018-10-17
EP3387431A4 true EP3387431A4 (de) 2019-05-01

Family

ID=59013433

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16874070.2A Withdrawn EP3387431A4 (de) 2015-12-11 2016-12-12 Systeme, verfahren und zusammensetzungen zur verbesserung der spezifität von nukleinsäurehybridisierung

Country Status (2)

Country Link
EP (1) EP3387431A4 (de)
WO (1) WO2017100792A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210254167A1 (en) * 2018-06-06 2021-08-19 Ramot At Tel-Aviv University Ltd. Multi-sample array chip for dna modification quantification
CN109116015B (zh) * 2018-09-27 2021-07-09 深圳大学 一种免封闭elisa酶标板的制作方法及使用方法
CN113150680B (zh) * 2019-12-25 2023-11-24 南京金斯瑞生物科技有限公司 一种芯片涂层、其制备方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003006675A2 (en) * 2001-07-11 2003-01-23 Baylor College Of Medicine Methods and devices based upon a novel form of nucleic acid duplex on a surface
WO2012142346A1 (en) * 2011-04-12 2012-10-18 Real-Time Genomics, Llc Method and apparatus for high accuracy genomic analysis platform utilizing hybridization and enhanced dissociation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003006675A2 (en) * 2001-07-11 2003-01-23 Baylor College Of Medicine Methods and devices based upon a novel form of nucleic acid duplex on a surface
WO2012142346A1 (en) * 2011-04-12 2012-10-18 Real-Time Genomics, Llc Method and apparatus for high accuracy genomic analysis platform utilizing hybridization and enhanced dissociation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ARNOLD VAINRUB ET AL: "Surface electrostatic effects in oligonucleotide microarrays: Control and optimization of binding thermodynamics", BIOPOLYMERS, 1 February 2003 (2003-02-01), New York, pages 265 - 270, XP055133705, Retrieved from the Internet <URL:http://onlinelibrary.wiley.com/doi/10.1002/bip.10271/abstract> DOI: 10.1002/bip.10271 *
See also references of WO2017100792A1 *

Also Published As

Publication number Publication date
EP3387431A1 (de) 2018-10-17
WO2017100792A1 (en) 2017-06-15

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