EP3374273A1 - Étiqueteuse pour récipients d'échantillons biologiques et microbiologiques - Google Patents

Étiqueteuse pour récipients d'échantillons biologiques et microbiologiques

Info

Publication number
EP3374273A1
EP3374273A1 EP15820883.5A EP15820883A EP3374273A1 EP 3374273 A1 EP3374273 A1 EP 3374273A1 EP 15820883 A EP15820883 A EP 15820883A EP 3374273 A1 EP3374273 A1 EP 3374273A1
Authority
EP
European Patent Office
Prior art keywords
area
container
containers
labeling machine
labeling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP15820883.5A
Other languages
German (de)
English (en)
Inventor
Fabio Sgarabottolo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
A Menarini Diagnostics Srl
Original Assignee
EOS SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITUB2015A005568A external-priority patent/ITUB20155568A1/it
Priority claimed from ITUB2015A005587A external-priority patent/ITUB20155587A1/it
Priority claimed from ITUB2015A005585A external-priority patent/ITUB20155585A1/it
Application filed by EOS SRL filed Critical EOS SRL
Publication of EP3374273A1 publication Critical patent/EP3374273A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65C—LABELLING OR TAGGING MACHINES, APPARATUS, OR PROCESSES
    • B65C3/00—Labelling other than flat surfaces
    • B65C3/06—Affixing labels to short rigid containers
    • B65C3/08—Affixing labels to short rigid containers to container bodies
    • B65C3/14—Affixing labels to short rigid containers to container bodies the container being positioned for labelling with its centre-line vertical
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00861—Identification of carriers, materials or components in automatic analysers printing and sticking of identifiers

Definitions

  • This patent relates to devices for the control and labeling of biological and microbiological sample containers and in particular relates to a new and improved labeling machine equipped with an enhanced labeling device.
  • This identification is performed by labeling the container or test tube when the sample is taken, where the label or tag applied to the container itself must unambiguously identify the patient and provide any further information if necessary.
  • the identification of the patient is normally performed by the hospital or laboratory personnel when the sample or specimen is taken.
  • the personnel collects and enters the patient data in a database, together with the tests or investigations to be conducted.
  • the personnel prepares and may even give the patient the labels and/or test tubes intended to collect the biological sample.
  • the patient goes to the dedicated area for the collection of the biological sample, where an operator receives the containers with the samples and marks them with the specific labels.
  • the operator In the case of a blood sample, the operator generally also draws the blood, prepares the container, and labels it.
  • the operator must then check that the patient and the sample type are consistent with the information provided by the container label.
  • samples are based only on the type of test tube and the color of the cap of the test tubes or containers in question, where the color of the cap identifies the type of investigation to be carried out and therefore which laboratory or equipment must process the sample.
  • Prior art includes devices and equipment which have the purpose of limiting human error in these procedures, as well as to optimize those procedures to save time.
  • Document US2015/0002867 relates to an apparatus for the identification of the patient and for the marking of their sample containers.
  • Said apparatus is made up of a portable device to process and store the patient's data by associating the patient's personal and biometric data, a device for the identification of the biometric data of the patient in question and for the reading of the portable device itself, a terminal for the operator connected with a server for data exchange, a labeling machine to mark the sample containers which includes a barcode label printer and a device for the physical application of the label on the container.
  • Said label application and identification equipment for sample containers in turn comprises a sensor to detect the presence of the container, a sensor to determine the length of the container, a sensor to determine the color of the container cap, and a sensor to determine the presence of labels already applied on the container.
  • Said apparatus therefore detects the biometric data of the patient, such as fingerprints, the color of the iris, etc., in order to check the identity of the patient, so as to avoid errors in patient identification and protect privacy, as well as to limit the possibility of mistaken associations of samples and patient.
  • biometric data of the patient such as fingerprints, the color of the iris, etc.
  • This procedure intends to reduce the possibility of erroneous labeling of containers, since the labeling is done after performing the sample container length and cap color check.
  • This kind of apparatus does not solve the problem of erroneous labeling of containers the content of which is not consistent with the sample expected, including an insufficient quantity or unsuitable quality to effectively proceed with the subsequent laboratory analysis.
  • Another drawback of these devices of the prior art is that all containers are processed in the same way and in the same time frame, while it is well known that some samples need to be sent for laboratory analysis very quickly, and some samples must be stored in thermally controlled environments to preserve the quality of some substances.
  • the time that elapses between the introduction of a test tube and when it comes out of the machine is rather prolonged because it includes the time required for data transfer from the terminal to the labeling machine, the time needed for the test tube to get from the insertion area to the area where it is checked and where specific controls take place, and the labeling area, which includes the time for the label to be printed and then applied.
  • test tubes are inserted in the labeling machine in a generally horizontal position, and is processed in generally maintaining this position.
  • test tube typically comes out of the labeling machine and is unloaded into a tray from which the operator picks it up to put it in a tray or tube rack to be sent to laboratories for analysis.
  • Standard procedures for the preparation of the test tubes usually require that the operator shake the contents of the test tube, even for a short period of time, to ensure the good quality of the sample.
  • the main object of the present invention is to verify the actual presence of the sample inside the container or test tube.
  • Another object of the present invention is to verify that the amount of the sample inside the container is adequate for the proper execution of the intended analyses.
  • a further object of the present invention is to verify that the quality of the sample inside the container is adequate, for the correct execution of the intended analysis.
  • Yet another object of the present invention is to maintain the sample in the ideal conditions to carry out all subsequent analyses.
  • Another important object is to establish a priority in the container labeling sequence as a function of the type of analysis to be conducted on the samples and the type of sample itself.
  • Still another important object of the present invention is to prevent unsuitable samples from being incorrectly sent to the analysis procedures.
  • a further object is to interact with the operator, to speed up and optimize not only the labeling procedure but also the subsequent treatment and analysis phases of the samples.
  • Yet another object of the present invention is to prevent the accidental spillage of contents from the containers while inside the labeling machine.
  • Still another object is to reduce the consequent demand for servicing interventions on the labeling machine.
  • the new type of improved labeling machine for the labeling of biological and microbiological sample containers, comprising in its main parts a machine body or frame, at least one electronic control unit suitable for the exchange of data relating to the containers with at least one external terminal, at least one input area of at least one container to be labeled, means of transport of that at least one container from the at least one input area to at least one labeling area, with means suitable to apply at least one label and/or other tag on the container itself, as well as means of transport of the at least one container from the at least one labeling area to the at least one unloading area accessible to the operator.
  • Said at least one input area is suitable for the insertion of at least one container in a substantially vertical position, that is, with its cap substantially facing upwards, and where the transport means and pick-up means always keep the container itself in the aforementioned substantially vertical position from the at least one input area to the at least one unloading area.
  • the new labeling machine comprises means for transporting the containers in question from the at least one input area to the at least one exchange area.
  • Said transport means comprise at least one revolving multiple position container holder in turn comprising a plurality of seats able to slide along a substantially horizontal loop, each seat being suitable to contain at least one of the containers in a substantially vertical position, and where the revolving multiple position container holder itself is suited to selectively position each of the seats first in the input area, for the subsequent insertion of the containers, and then to the exchange area, to allow the pickup of the containers, transported to the labeling area.
  • the at least one container is inserted from above into the seat of the revolving multiple position container holder positioned in the input area.
  • the pickup and translation means extract from below the at least one container from the seat of the revolving multiple position container holder positioned in the aforementioned exchange area.
  • the pick-up means translate in sequence one or more containers in a substantially vertical direction between the exchange area and the labeling area.
  • the new labeling machine may also include at least one control area in which one or more sensors, for example able to detect the test tube length, the cap color, etc., check certain characteristics of the test tube prior performing the subsequent labeling.
  • control area and the labeling area are substantially aligned in a vertical direction.
  • the pick-up means take one or more of the containers at a time from the exchange area and translate them in the vertical direction between the exchange area and the control area, and between the control area and the labeling area.
  • the new labeling machine receives the containers in an upright position, and performs all operations on them, that is, the labeling and any required control, until they are unloaded, keeping the containers in that position.
  • the operator can quickly insert the containers in the seats of the revolving multiple position container holder as it moves and presents a free seat for the insertion of a new container at the at least one input area.
  • the new labeling machine also comprises at least one sensor to check the volume of the sample in the container.
  • Said at least one sensor for the volumetric control is installed in said at least one control area, which may coincide with or preferably not coincide with said at least one labeling area.
  • Said at least one control sensor may comprise at least one light source and/or at least one video camera, and is suited to verify the presence of the contents and/or quantify the volume of the contents.
  • the new labeling machine also preferably comprises one or more additional sensors for the recognition of the container type, the sensors comprising: at least one sensor to check the container length and/or at least one sensor to check the container diameter and/or at least one sensor to check the container shape and/or at least one sensor to check the position of the container cap, distinguishing for example between containers with caps positioned laterally from those with caps positioned axially, and/or at least one sensor to check the cap color, and/or at least one sensor to check the cap shape.
  • Said one or more sensors may be installed in said at least one control area.
  • Said sensors in question are also suited to detect the quality of the sample in the container, for example by verifying the levels of serum, hemolysis, lipemia, jaundice, etc.
  • control area is preferably upstream of the labeling area, and therefore the new labeling machine also comprises means of transport of said at least one container from said at least one control area to said at least one labeling area.
  • the presence of the sample and its volume inside the container is checked before the labeling operations.
  • This error may be reported on an interface of the labeling machine or on said external terminal connected to said labeling machine itself.
  • the labeling machine may label the container and then transport it to said at least one output area, in combination with an alarm signaling the lack or insufficient volume of the sample material.
  • the new labeling machine activates the alarm.
  • Said labeling machine may also be designed to accept and carry out the volume check to verify the presence and sufficient volume of the sample inside the containers even on already labeled containers.
  • the new labeling machine may also include at least one additional output area to which said container is transported, with or without the label applied, in the case in which one or more of the aforementioned sensors detect unexpected or abnormal values, for example, in the case it is found that: the sample is lacking, the sample has an insufficient volume, the quality of the sample is inadequate, the container shape and/or container size and/or cap color and/or cap shape is different from what is expected.
  • said transport means pick up the one or more containers from said control area and transport them to said main output area.
  • said output area and/or said additional output area are located substantially external with respect to said machine's body or in any case in a position such that, in case of accidental spillage, no material can enter the machine and damage its components.
  • Said labeling machine is suited to apply labels and/or tags on the containers in said labeling area and preferably comprises at least one main bar code printer for the labels and means for applying said printed labels on said containers, preferably on the side of the containers themselves.
  • Said labeling machine may also be designed to apply RFID or microchip labels.
  • the new labeling machine comprises devices suited to prevent the label from being positioned on the container in a different position than any pre-existing labels, which could cover the entire side of the container and prevent the contents from being viewed.
  • the new labeling machine also comprises at least one sensor to detect any preexisting labels on said container, and means to carry out an axial rotation of said container in order to apply the new label substantially superimposed on any pre-existing label detected.
  • the new labeling machine may also include means to carry out the axial translation of said container and/or said means to apply the label such that the height of the label may also be selected.
  • the labeling machine may also immediately verify the type of container introduced and the specific procedures to be implemented for one or more of them.
  • said container shall be equipped with one or more predetermined characteristics so that, once those characteristics are detected, the new labeling machine labels the container and signals the operator so that the operator will handle the container appropriately such as, for example, putting the container in a thermally controlled environment.
  • the sample material in the case in which the sample material must be subjected to urgent procedures, like for example determining load curves, the sample must be sent to the analytical laboratory within a pre-established time-frame.
  • said container shall be equipped with one or more predetermined characteristics so that once those characteristics are detected, the new labeling machine labels the container and signals the operator so that the operator will handle the container appropriately like for example forwarding the container to the analytical laboratory within the expected time-frame.
  • the new labeling machine may also include at least one additional printer for printing labels to be applied on other types of containers or products generally not suitable to being introduced in the labeling machine, said additional printer being in any case connected to the control unit of the labeling machine itself.
  • the new apparatus for the control and labeling of biological and microbiological sample containers comprises at least one of said aforementioned labeling machines; at least one server to receive and store data, including data relating to the patient, the type of biological samples to be collected, and the type of analysis to be carried out; and at least one external terminal communicating with said at least one server and with said labeling machine.
  • the new apparatus preferably also comprises one or more visual signaling devices and/or audible alarms, installed on said labeling machine and/or on said external terminal and suited to signal when said one or more sensors detect incorrect or unexpected values or other specific conditions.
  • the new apparatus may also be designed so that the preferred sequence in which the containers must be introduced in the labeling machine, that is, before or after loading them with the sample material, is displayed on said external terminal and/or said labeling machine in communication with said server.
  • the new apparatus may further comprise at least one external device to verify and/or store a record of the labels applied or printed by said labeling machine.
  • the new labeling machine may also comprise means to read and/or write the batch code and/or expiration date of the containers, so as to facilitate the tracking of the containers themselves.
  • said output area comprises at least one tray, chute or seat suited for said at least one container coming out of said labeling machine, and where said seat oscillates in order to carry out an initial mixing of the biological sample inside said container.
  • said aforementioned seat comprises a chute in which one or more od said containers are in a generally inclined or substantially horizontal position.
  • said chute is connected to mechanical means able to cause said chute to oscillate at a predetermined angle with respect to the horizontal plane, for example between +10° and -10°.
  • Said oscillating motion may be continuous or activated only when said chute receives one or more containers.
  • said additional output area comprises at least one oscillating seat, chute or tray.
  • Figure 1 is a schematic representation of the new equipment (A) for the labeling of biological and microbiological sample containers, comprising a labeling machine (E), a server (S) to receive and store data including data relating to the patient, to the type of biological samples to be collected, and the type of analyses to be performed, an external terminal (C) communicating with said at least one server (S) and with said labeling machine (E).
  • A labeling machine
  • S server
  • C communicating with said at least one server (S) and with said labeling machine (E).
  • Figure 2 is a front view of the labeling machine (E) where a main output area (6) and an additional output area (7) are visible.
  • Fi gure 3 is a schematic cross section representation of the new labeling machine (E) where some internal components are visible.
  • Figure 4 shows a detail of Figure 3, where the oscillating chute (61) of the main output area (6) is visible.
  • Figure 5 shows a side view of the labeling machine (E) without the machine body (1) where the internal components are visible.
  • This is a new labeling machine (E) for biological and microbiological sample containers comprising a machine body or frame (1), at least one electronic control unit, suitable for the exchange of data relating to containers with at least one external terminal (C), at least one input area (2) of at least one container to be labeled, pick-up and transport means (3, 22) of said at least one container introduced from said input area (2) to said at least one labeling area (5) and transport means (22) of said at least one container from said labeling area (5) to said at least one output area (6, 7) which is in turn accessible to the user or operator.
  • Said at least one labeling area (5) comprises means for applying at least one label and/or other tag on said container in question.
  • Said at least one input area (2) is suited to contain one or more of said containers positioned upright, that is, with their caps facing substantially upwards, and wherein said pick-up and transport means (22, 3) always keep said containers in said vertical position from said input area (2) to said output area (6, 7).
  • Said transport means (22, 3) comprise a revolving multiple position container holder (3) in turn comprising a cylindrical body or drum (32), rotating around its longitudinal axis (3z), in turn oriented in the vertical direction (Z), a plurality of seats (31, 31i) distributed along a coaxial circumference with respect to said drum (32), with each seat (31, 3 li) being suited to contain one of the containers in a substantially vertical position, that is, with the cap facing upwards.
  • Said revolving multiple position container holder (3) by rotating, selectively positions each of said seats (31, 3 li) first at said at least one input area (2), to allow the introduction of containers, and then at said at least one exchange area (21), where one or more of said pick- up and transport means (22) pick up said containers to be transported to said labeling area (5).
  • said at least one container is inserted from above into the seat (3 li) of said revolving multiple position container holder (3) which is positioned in that moment at said input area (2), while in said exchange area (21), said pick-up and transport means (22) remove said at least one container from below the seat of said revolving multiple position container holder (3) which in that moment is positioned in said exchange area (21).
  • Said pickup and transport means (22) comprise for example means (221) to grasp said containers from below, and translate them along a guide (222) oriented in said vertical direction (Z).
  • the new labeling machine also comprises at least one control area (4) with one or more sensors for the detection of the contents and/or of the container, and wherein said pick-up and transport means (22) translate said one or more containers from said pickup area (21) to said control area (4) and from said control area (4) to said labeling area (5) and/or to said output area (6, 7).
  • control area (4) and said labeling area (5) are substantially aligned in the vertical direction (Z), and wherein said transport means (22) translate the containers axially from said control area (4) to said labeling area (5).
  • the new labeling machine (E) comprises at least one volume sensor, suited to verify and/or quantify the volume of the sample contained in the at least one container and/or one or more sensors suited to detect the quality of the sample in said container, by verifying the levels of serum, hemolysis, lipemia, jaundice, etc. and/or one or more sensors for the recognition of the container.
  • the new labeling machine (E) also comprises at least one sensor for the detection of any preexisting labels on said container and means to carry out an axial rotation and/or the axial translation of said container to position it so that the new label is applied substantially superimposed on any pre-existing label detected.
  • the new labeling machine also includes at least one additional output area (7) and where said transport means (22) translate said one or more containers from said control area (4) to said additional output area (7), with or without labeling, in the case in which one or more of said sensors detect incorrect values or different values from those expected or with respect to the specific pre-set conditions.
  • Said main output area (6) and/or said additional output area (7) are positioned substantially external to said machine body (1) or in any case in a position such that, in the case of an accidental spill, the material cannot enter the machine and damage its components.
  • said main output area (6) is for example located on the bottom (11) of the labeling machine and comprises a chute or tray (61) with side walls (62), such that any spillage of material cannot come out of them and soil the inside of the machine.
  • said additional output area (7) comprises a chute (71) inclined downwards and towards the outside protruding laterally from the machine body (1).
  • said containers may also be positioned upside down without risking spills inside the machine.
  • said output area (6) comprises at least one tray, chute (61) or seat in general for said at least one container exiting said labeling machine (E), and wherein said seat or chute (61) oscillates to carry out an initial mixing of the biological sample contained in said container.
  • said containers are in a generally inclined or substantially horizontal position, and wherein said chute (61) is connected to mechanical means (63, 64) suited to provoke the oscillation of said chute (61) at a predetermined angle with respect to the horizontal plane.
  • Said oscillating motion may be continuous or, alternatively, may be activated only when said chute (61) has one or more of said containers in it.
  • said main output area (6) comprises at least one tray or chute (61), preferably with containment side walls (62), positioned for example on the bottom (11) of said machine body (1).
  • said mechanical means comprise a cam (63) with an arm (64) connected to said chute (61), wherein the rotation of said cam (63) causes the oscillation of said chute (61).
  • said chute oscillates around an axis (6x) arranged substantially horizontally or in any case substantially parallel to the bottom of said chute (61).
  • Said axis (6x) is for example oriented parallel to the length of the chute (61), from the inside towards the outside of the machine.
  • said additional output area (7) may also comprise at least one oscillating seat, chute (71) or tray.
  • the new apparatus (A) shown in Figure 1 also includes one or more visual signaling devices and/or audible alarms, installed on said labeling machine (E) and/or on said external terminal (C) and suited to signal when said one or more sensors detect incorrect or unexpected values or other specific pre-set conditions.
  • Said external terminal (C) and/or said labeling machine (E) comprise means to display the sequence of containers to be inserted in said labeling machine (E).

Landscapes

  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Labeling Devices (AREA)

Abstract

L'invention concerne une étiqueteuse (E) pour récipients d'échantillons biologiques et microbiologiques adaptée à l'échange de données relatives aux récipients avec au moins un terminal externe (C), comprenant une zone d'entrée (2) destinée aux récipients à étiqueter, une zone de commande (4) desdits récipients, une zone d'étiquetage (5) dotée d'un moyen permettant d'appliquer au moins une étiquette et/ou un autre marquage sur lesdits récipients, un moyen de transport (3) desdits récipients de ladite zone d'entrée (2) vers ladite zone de commande (4) et/ou vers ladite zone d'étiquetage (5).
EP15820883.5A 2015-11-13 2015-11-16 Étiqueteuse pour récipients d'échantillons biologiques et microbiologiques Withdrawn EP3374273A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
ITUB2015A005568A ITUB20155568A1 (it) 2015-11-13 2015-11-13 Etichettatrice per contenitori di campioni biologici e microbiologici e apparato per l'etichettatura di contenitori di campioni biologici e microbiologici
ITUB2015A005587A ITUB20155587A1 (it) 2015-11-13 2015-11-13 Etichettatrice per contenitori di campioni biologici e microbiologici con scivolo basculante
ITUB2015A005585A ITUB20155585A1 (it) 2015-11-13 2015-11-13 Etichettatrice per contenitori di campioni biologici e microbiologici
PCT/IB2015/058844 WO2017081524A1 (fr) 2015-11-13 2015-11-16 Étiqueteuse pour récipients d'échantillons biologiques et microbiologiques

Publications (1)

Publication Number Publication Date
EP3374273A1 true EP3374273A1 (fr) 2018-09-19

Family

ID=55073067

Family Applications (1)

Application Number Title Priority Date Filing Date
EP15820883.5A Withdrawn EP3374273A1 (fr) 2015-11-13 2015-11-16 Étiqueteuse pour récipients d'échantillons biologiques et microbiologiques

Country Status (2)

Country Link
EP (1) EP3374273A1 (fr)
WO (1) WO2017081524A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12066363B2 (en) * 2018-07-18 2024-08-20 Enrico BICOCCHI System and method for preserving a surgically explanted tissue sample

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP058197A0 (en) * 1997-11-27 1997-12-18 A.I. Scientific Pty Ltd Pathology sample tube distributor
ITRM20050116A1 (it) * 2005-03-15 2006-09-16 Antolini Pietro Macchina per la selezione e l'etichettatura di provette per laboratori d'analisi e simili.
CN102459008B (zh) * 2009-06-05 2014-01-01 科技医疗株式会社 用于试管自动制备设备的贴标机
ITMI20120044A1 (it) 2012-01-17 2013-07-18 Inpeco Ip Ltd Apparato di etichettatura tracciabile di contenitori di prodotti biologici.
WO2014171665A1 (fr) * 2013-04-15 2014-10-23 에너지움 주식회사 Préhenseur de tube à essai, unité d'étiquetage de tube à essai et dispositif de préparation de tube à essai les comportant
KR20140124486A (ko) * 2013-04-17 2014-10-27 주식회사 크레도웨이 시험관용 라벨 자동 부착 장치

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