EP3351236B1 - Octocylenfreies sonnenschutzmittel mit polyglyceryl-10 stearat - Google Patents
Octocylenfreies sonnenschutzmittel mit polyglyceryl-10 stearat Download PDFInfo
- Publication number
- EP3351236B1 EP3351236B1 EP18150549.6A EP18150549A EP3351236B1 EP 3351236 B1 EP3351236 B1 EP 3351236B1 EP 18150549 A EP18150549 A EP 18150549A EP 3351236 B1 EP3351236 B1 EP 3351236B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- preparation
- inci
- polyglyceryl
- use according
- ethylhexyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229940061570 polyglyceryl-10 stearate Drugs 0.000 title claims description 20
- 230000000475 sunscreen effect Effects 0.000 title description 8
- 239000000516 sunscreening agent Substances 0.000 title description 8
- 238000002360 preparation method Methods 0.000 claims description 122
- OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 claims description 87
- -1 fatty acid ester Chemical class 0.000 claims description 39
- FDATWRLUYRHCJE-UHFFFAOYSA-N diethylamino hydroxybenzoyl hexyl benzoate Chemical compound CCCCCCOC(=O)C1=CC=CC=C1C(=O)C1=CC=C(N(CC)CC)C=C1O FDATWRLUYRHCJE-UHFFFAOYSA-N 0.000 claims description 27
- 239000002537 cosmetic Substances 0.000 claims description 25
- FMRHJJZUHUTGKE-UHFFFAOYSA-N Ethylhexyl salicylate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1O FMRHJJZUHUTGKE-UHFFFAOYSA-N 0.000 claims description 23
- 238000000034 method Methods 0.000 claims description 23
- TYYHDKOVFSVWON-UHFFFAOYSA-N 2-butyl-2-methoxy-1,3-diphenylpropane-1,3-dione Chemical compound C=1C=CC=CC=1C(=O)C(OC)(CCCC)C(=O)C1=CC=CC=C1 TYYHDKOVFSVWON-UHFFFAOYSA-N 0.000 claims description 16
- 229960005193 avobenzone Drugs 0.000 claims description 16
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 15
- 229960001630 diethylamino hydroxybenzoyl hexyl benzoate Drugs 0.000 claims description 15
- 239000000194 fatty acid Substances 0.000 claims description 15
- 229930195729 fatty acid Natural products 0.000 claims description 15
- JGUMTYWKIBJSTN-UHFFFAOYSA-N 2-ethylhexyl 4-[[4,6-bis[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 JGUMTYWKIBJSTN-UHFFFAOYSA-N 0.000 claims description 14
- DXGLGDHPHMLXJC-UHFFFAOYSA-N oxybenzone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1 DXGLGDHPHMLXJC-UHFFFAOYSA-N 0.000 claims description 14
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 12
- XVAMCHGMPYWHNL-UHFFFAOYSA-N bemotrizinol Chemical compound OC1=CC(OCC(CC)CCCC)=CC=C1C1=NC(C=2C=CC(OC)=CC=2)=NC(C=2C(=CC(OCC(CC)CCCC)=CC=2)O)=N1 XVAMCHGMPYWHNL-UHFFFAOYSA-N 0.000 claims description 12
- 229940068171 ethyl hexyl salicylate Drugs 0.000 claims description 12
- 239000004753 textile Substances 0.000 claims description 12
- UVCJGUGAGLDPAA-UHFFFAOYSA-N ensulizole Chemical class N1C2=CC(S(=O)(=O)O)=CC=C2N=C1C1=CC=CC=C1 UVCJGUGAGLDPAA-UHFFFAOYSA-N 0.000 claims description 11
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 11
- 239000004904 UV filter Substances 0.000 claims description 10
- FMJSMJQBSVNSBF-UHFFFAOYSA-N octocrylene Chemical group C=1C=CC=CC=1C(=C(C#N)C(=O)OCC(CC)CCCC)C1=CC=CC=C1 FMJSMJQBSVNSBF-UHFFFAOYSA-N 0.000 claims description 8
- 229960000601 octocrylene Drugs 0.000 claims description 8
- 229960001173 oxybenzone Drugs 0.000 claims description 7
- 239000004615 ingredient Substances 0.000 claims description 6
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 5
- 239000007983 Tris buffer Substances 0.000 claims description 5
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 claims description 5
- 239000003995 emulsifying agent Substances 0.000 claims description 5
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 claims description 5
- HEOCBCNFKCOKBX-RELGSGGGSA-N (1s,2e,4r)-4,7,7-trimethyl-2-[(4-methylphenyl)methylidene]bicyclo[2.2.1]heptan-3-one Chemical compound C1=CC(C)=CC=C1\C=C/1C(=O)[C@]2(C)CC[C@H]\1C2(C)C HEOCBCNFKCOKBX-RELGSGGGSA-N 0.000 claims description 4
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 4
- JRJBVWJSTHECJK-PKNBQFBNSA-N 3-Methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one Chemical compound CC(=O)C(\C)=C\C1C(C)=CCCC1(C)C JRJBVWJSTHECJK-PKNBQFBNSA-N 0.000 claims description 4
- ZCTQGTTXIYCGGC-UHFFFAOYSA-N Benzyl salicylate Chemical compound OC1=CC=CC=C1C(=O)OCC1=CC=CC=C1 ZCTQGTTXIYCGGC-UHFFFAOYSA-N 0.000 claims description 4
- DKMROQRQHGEIOW-UHFFFAOYSA-N Diethyl succinate Chemical compound CCOC(=O)CCC(=O)OCC DKMROQRQHGEIOW-UHFFFAOYSA-N 0.000 claims description 4
- GLZPCOQZEFWAFX-UHFFFAOYSA-N Geraniol Chemical compound CC(C)=CCCC(C)=CCO GLZPCOQZEFWAFX-UHFFFAOYSA-N 0.000 claims description 4
- SESFRYSPDFLNCH-UHFFFAOYSA-N benzyl benzoate Chemical compound C=1C=CC=CC=1C(=O)OCC1=CC=CC=C1 SESFRYSPDFLNCH-UHFFFAOYSA-N 0.000 claims description 4
- QMVPMAAFGQKVCJ-UHFFFAOYSA-N citronellol Chemical compound OCCC(C)CCC=C(C)C QMVPMAAFGQKVCJ-UHFFFAOYSA-N 0.000 claims description 4
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims description 4
- CDOSHBSSFJOMGT-UHFFFAOYSA-N linalool Chemical compound CC(C)=CCCC(C)(O)C=C CDOSHBSSFJOMGT-UHFFFAOYSA-N 0.000 claims description 4
- 229960005323 phenoxyethanol Drugs 0.000 claims description 4
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims description 3
- 239000001490 (3R)-3,7-dimethylocta-1,6-dien-3-ol Substances 0.000 claims description 2
- QMVPMAAFGQKVCJ-SNVBAGLBSA-N (R)-(+)-citronellol Natural products OCC[C@H](C)CCC=C(C)C QMVPMAAFGQKVCJ-SNVBAGLBSA-N 0.000 claims description 2
- CDOSHBSSFJOMGT-JTQLQIEISA-N (R)-linalool Natural products CC(C)=CCC[C@@](C)(O)C=C CDOSHBSSFJOMGT-JTQLQIEISA-N 0.000 claims description 2
- 229940015975 1,2-hexanediol Drugs 0.000 claims description 2
- 229940031723 1,2-octanediol Drugs 0.000 claims description 2
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 claims description 2
- QWGRWMMWNDWRQN-UHFFFAOYSA-N 2-methylpropane-1,3-diol Chemical compound OCC(C)CO QWGRWMMWNDWRQN-UHFFFAOYSA-N 0.000 claims description 2
- DCEUMOZSMAUPSP-UHFFFAOYSA-N 3,7-dimethyloct-6-enyl 3-methylbut-2-enoate Chemical compound CC(C)=CCCC(C)CCOC(=O)C=C(C)C DCEUMOZSMAUPSP-UHFFFAOYSA-N 0.000 claims description 2
- ORMHZBNNECIKOH-UHFFFAOYSA-N 4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde Chemical compound CC(C)(O)CCCC1=CCC(C=O)CC1 ORMHZBNNECIKOH-UHFFFAOYSA-N 0.000 claims description 2
- YVSNOTITPICPTB-UHFFFAOYSA-N 4-methyl-2-(2-methylpropyl)oxan-4-ol Chemical compound CC(C)CC1CC(C)(O)CCO1 YVSNOTITPICPTB-UHFFFAOYSA-N 0.000 claims description 2
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 claims description 2
- 239000005770 Eugenol Substances 0.000 claims description 2
- 239000005792 Geraniol Substances 0.000 claims description 2
- GLZPCOQZEFWAFX-YFHOEESVSA-N Geraniol Natural products CC(C)=CCC\C(C)=C/CO GLZPCOQZEFWAFX-YFHOEESVSA-N 0.000 claims description 2
- DUKPKQFHJQGTGU-UHFFFAOYSA-N Hexyl salicylic acid Chemical compound CCCCCCOC(=O)C1=CC=CC=C1O DUKPKQFHJQGTGU-UHFFFAOYSA-N 0.000 claims description 2
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 claims description 2
- SLHPMAOXNSLXEH-ZGVCCVRISA-N [(1r,2s,5r)-5-methyl-2-propan-2-ylcyclohexyl] 5-oxopyrrolidine-2-carboxylate Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)C1NC(=O)CC1 SLHPMAOXNSLXEH-ZGVCCVRISA-N 0.000 claims description 2
- 239000001361 adipic acid Substances 0.000 claims description 2
- 235000011037 adipic acid Nutrition 0.000 claims description 2
- 239000001518 benzyl (E)-3-phenylprop-2-enoate Substances 0.000 claims description 2
- 229960002903 benzyl benzoate Drugs 0.000 claims description 2
- NGHOLYJTSCBCGC-QXMHVHEDSA-N benzyl cinnamate Chemical compound C=1C=CC=CC=1\C=C/C(=O)OCC1=CC=CC=C1 NGHOLYJTSCBCGC-QXMHVHEDSA-N 0.000 claims description 2
- JGQFVRIQXUFPAH-UHFFFAOYSA-N beta-citronellol Natural products OCCC(C)CCCC(C)=C JGQFVRIQXUFPAH-UHFFFAOYSA-N 0.000 claims description 2
- DHNRXBZYEKSXIM-UHFFFAOYSA-N chloromethylisothiazolinone Chemical compound CN1SC(Cl)=CC1=O DHNRXBZYEKSXIM-UHFFFAOYSA-N 0.000 claims description 2
- NGHOLYJTSCBCGC-UHFFFAOYSA-N cis-cinnamic acid benzyl ester Natural products C=1C=CC=CC=1C=CC(=O)OCC1=CC=CC=C1 NGHOLYJTSCBCGC-UHFFFAOYSA-N 0.000 claims description 2
- 235000000484 citronellol Nutrition 0.000 claims description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 2
- YSRSBDQINUMTIF-UHFFFAOYSA-N decane-1,2-diol Chemical compound CCCCCCCCC(O)CO YSRSBDQINUMTIF-UHFFFAOYSA-N 0.000 claims description 2
- WSDISUOETYTPRL-UHFFFAOYSA-N dmdm hydantoin Chemical compound CC1(C)N(CO)C(=O)N(CO)C1=O WSDISUOETYTPRL-UHFFFAOYSA-N 0.000 claims description 2
- 229960002217 eugenol Drugs 0.000 claims description 2
- 229940113087 geraniol Drugs 0.000 claims description 2
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims description 2
- WNLRTRBMVRJNCN-UHFFFAOYSA-N hexanedioic acid Natural products OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 claims description 2
- 229930007744 linalool Natural products 0.000 claims description 2
- JPTOCTSNXXKSSN-UHFFFAOYSA-N methylheptenone Chemical compound CCCC=CC(=O)CC JPTOCTSNXXKSSN-UHFFFAOYSA-N 0.000 claims description 2
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 claims description 2
- AEIJTFQOBWATKX-UHFFFAOYSA-N octane-1,2-diol Chemical compound CCCCCCC(O)CO AEIJTFQOBWATKX-UHFFFAOYSA-N 0.000 claims description 2
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 2
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- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 claims description 2
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- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims description 2
- XMGQYMWWDOXHJM-UHFFFAOYSA-N limonene Chemical compound CC(=C)C1CCC(C)=CC1 XMGQYMWWDOXHJM-UHFFFAOYSA-N 0.000 claims 2
- UWKAYLJWKGQEPM-LBPRGKRZSA-N linalyl acetate Chemical compound CC(C)=CCC[C@](C)(C=C)OC(C)=O UWKAYLJWKGQEPM-LBPRGKRZSA-N 0.000 claims 2
- NCZPCONIKBICGS-UHFFFAOYSA-N 3-(2-ethylhexoxy)propane-1,2-diol Chemical compound CCCCC(CC)COCC(O)CO NCZPCONIKBICGS-UHFFFAOYSA-N 0.000 claims 1
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 claims 1
- YKPUWZUDDOIDPM-SOFGYWHQSA-N capsaicin Chemical compound COC1=CC(CNC(=O)CCCC\C=C\C(C)C)=CC=C1O YKPUWZUDDOIDPM-SOFGYWHQSA-N 0.000 claims 1
- 229940100524 ethylhexylglycerin Drugs 0.000 claims 1
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- AXIUTKTZNZMMSI-UHFFFAOYSA-N octan-3-yl 2-cyano-3,3-diphenylprop-2-enoate Chemical compound C=1C=CC=CC=1C(=C(C#N)C(=O)OC(CC)CCCCC)C1=CC=CC=C1 AXIUTKTZNZMMSI-UHFFFAOYSA-N 0.000 claims 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 11
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 10
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- 229960003080 taurine Drugs 0.000 description 1
- 229960002663 thioctic acid Drugs 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- PJHKBYALYHRYSK-UHFFFAOYSA-N triheptanoin Chemical compound CCCCCCC(=O)OCC(OC(=O)CCCCCC)COC(=O)CCCCCC PJHKBYALYHRYSK-UHFFFAOYSA-N 0.000 description 1
- 229940078561 triheptanoin Drugs 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical class [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4966—Triazines or their condensed derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/415—Aminophenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
Definitions
- UVA and UVB filters are summarized in most industrialized countries in the form of positive lists such as Appendix 7 of the Cosmetics Regulation.
- Cosmetic sunscreens have the problem that a large number of UV filters are not particularly soluble in the preparations.
- the solubility of 4- (tert-butyl) -4'-methoxydibenzoylmethane (INCI butyl methoxydibenzoylmethane) and triazine derivatives is a problem for developers when developing preparations with a high sun protection factor and high UV filter content.
- the liquid UV-B filter octocrylene was used as a UV filter and solvent.
- Octocrylene also serves to photostabilize 4- (tert-butyl) -4'-methoxydibenzoylmethane.
- the object of the present invention to eliminate the disadvantages of the prior art and to develop a sunscreen with a high sun protection factor in which the UV filters (in particular 4- (tert-butyl) -4'-methoxydibenzoylmethane and triazine derivatives, especially 2,4-bis - ⁇ [4- (2-ethylhexyloxy) -2-hydroxy] phenyl ⁇ -6- (4-methoxyphenyl) -1,3,5-triazine (INCI: bis-ethylhexyloxyphenol methoxyphenyl triazines ) and 2,4,6-tris- [anilino- (p-carbo-2'-ethyl-1'-hexyloxy)] - 1,3,5-triazine (INCI: ethylhexyl triazone)) can be stably dissolved without Octocrylene is used as a solvent and stabilizer.
- the UV filters in particular 4- (tert-but
- Cosmetic preparations such as sunscreen preparations which are applied to the skin regularly (intentionally or unintentionally) come into contact with clothing and items of laundry (for example towels) on which they (for example as “abrasion” or because they are “absorbed” by the fiber materials) partly stick. In this way, depending on the type of ingredients, stains and discolouration occur, especially on light textiles.
- UVA and broadband filters such as 4- (tert-butyl) -4'-methoxydibenzoylmethane (INCI butyl methoxydibenzoylmethane), (2 - [- 4- (diethylamino) -2-hydroxybenzoyl] benzoic acid hexyl ester (INCI : Diethylamino hydroxybenzoyl hexyl benzoate) and 2,4-bis - ⁇ [4- (2-ethylhexyloxy) -2-hydroxy] phenyl ⁇ -6- (4-methoxyphenyl) -1,3,5-triazine (INCI : Bis-Ethylhexyloxyphenol Methoxyphenyl Triazin)
- the stains can hardly be removed by washing with conventional detergents and are even intensified during the washing process through interactions with ions in the washing water.
- UV-A filters such as 4- (tert-butyl) -4 ' -methoxydibenzoylmethane (INCI butyl methoxydibenzoylmethane) and (2 - [- 4- (diethylamino) -2-hydroxybenzoyl] benzoic acid hexyl ester (INCI: diethylamino hydroxybenzoyl hexyl benzoate) as well as optionally broadband filters such as bis-ethylhexyloxyphenol methoxyphenyl triazines, which contains more easily which contains Allow preparation to wash out contaminated textiles.
- non-water-soluble UV-A filters such as 4- (tert-butyl) -4 ' -methoxydibenzoylmethane (INCI butyl methoxydibenzoylmethane) and (2 - [- 4- (diethylamino) -2-hydroxybenzoyl] benzoic acid hexyl ester
- the objects are also achieved by a method for increasing the washability of organic, oil-soluble UV-A filters and / or organic, oil-soluble broadband filters made of textiles, which are combined with a cosmetic preparation contains UV-A filters and / or broadband filters, are contaminated, characterized in that polyglyceryl fatty acid ester is added to the cosmetic preparation, and by a Process for reducing the textile stains caused by cosmetic preparations containing UV light protection filters, characterized in that the cosmetic contains polyglyceryl fatty acid ester as an emulsifier.
- the tasks are solved by the use of polyglyceryl fatty acid esters in cosmetic preparations containing UV light protection filters to facilitate the washability of the UV light protection filters from textiles contaminated with the preparations.
- formulations “according to the invention”, “preparation according to the invention” etc. always refer to the preparations, methods and uses according to the invention, i.e. also to preparations in which the uses according to the invention are realized and preparations with which the method according to the invention is carried out.
- polyglyceryl fatty acid ester which is particularly preferred according to the invention is with regard to the methods according to the invention and those according to the invention.
- Use polyglyceryl-10 stearate ICI Polyglyceryl-10 stearate).
- the preparation is a combination of preparation 2,4-bis - ⁇ [4- (2-ethylhexyloxy) -2-hydroxy] phenyl ⁇ -6- (4-methoxyphenyl) -1,3 , 5-triazine (INCI: bis-ethylhexyloxyphenol methoxyphenyl triazine) and 2,4,6-tris [anilino- (p-carbo-2'-ethyl-1'-hexyloxy)] - 1,3,5-triazine ( INCI: Ethylhexyl Triazone) contains.
- Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation contains 2-phenylbenzimidazole-5-sulfonic acid salts and / or 2-ethylhexyl 2-hydroxybenzoate (INCI: ethylhexyl salicylate).
- Preferred embodiments of the present invention are characterized in that the preparation contains 2-phenylbenzimidazole-5-sulfonic acid salts and 2-ethylhexyl 2-hydroxybenzoate (INCI: ethylhexyl salicylate).
- the preparation is based on hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI: diethylamino hydroxybenzoyl hexyl benzoate) in a concentration of 0.05 to 1.5% by weight on the total weight of the preparation.
- the preparation hexyl 2- [4- (diethylamino) -2-hydroxybenzoyl] benzoate (INCI: Diethylamino hydroxybenzoyl hexyl benzoate) in a concentration of 0.05 to 1.0% by weight, based on the total weight of the preparation.
- the preparation contains 4- (tert-butyl) -4'-methoxydibenzoylmethane (INCI butyl methoxydibenzoylmethane) in a concentration of 1.00 to 5.00% by weight, based on the total weight of the preparation.
- the preparation contains 4- (tert-butyl) -4'-methoxydibenzoylmethane (INCI butyl methoxydibenzoylmethane) in a concentration of 1.25 to 4.75% by weight, based on the total weight of the preparation.
- the weight ratio of diethylamino hydroxybenzoyl hexyl benzoate to butyl methoxydibenzoylmethane should be from 0.2: 1 to 1: 5.
- Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation contains polyglyceryl-10 stearate (INCI polyglyceryl-10 stearate) in a concentration of 0.05 to 1.25% by weight, based on the total weight of the preparation.
- polyglyceryl-10 stearate INCI polyglyceryl-10 stearate
- Preferred embodiments of the present invention are characterized in that the preparation contains polyglyceryl-10 stearate (INCI polyglyceryl-10 stearate) in a concentration of 0.5 to 1.00% by weight, based on the total weight of the preparation.
- polyglyceryl-10 stearate INCI polyglyceryl-10 stearate
- the preparation according to the invention contains 2,4-bis - ⁇ [4- (2-ethylhexyloxy) -2-hydroxy] phenyl ⁇ -6- (4-methoxyphenyl) -1,3,5-triazine (INCI: bis- Ethylhexyloxyphenol methoxyphenyl triazine) and no 2,4,6-tris- [anilino- (p-carbo-2'-ethyl-1'-hexyloxy)] - 1,3,5-triazine (INCI: ethylhexyl triazone), so the bis-ethylhexyloxyphenol methoxyphenyl triazine in the preparation in a concentration of 0.05 to 4.00% by weight, based on the total weight of the preparation, advantageously used according to the invention.
- the preparation according to the invention does not contain 2,4-bis - ⁇ [4- (2-ethylhexyloxy) -2-hydroxy] phenyl ⁇ -6- (4-methoxyphenyl) -1,3,5-triazine (INCI: bis -Ethylhexyloxyphenol methoxyphenyl triazine) but 2,4,6-tris- [anilino- (p-carbo-2'-ethyl-1'-hexyloxy)] - 1,3,5-triazine (INCI: ethylhexyl triazone), so the ethylhexyl triazone in the preparation is advantageously used according to the invention in a concentration of 0.1 to 4.5% by weight, based on the total weight of the preparation.
- the preparation according to the invention contains both 2,4-bis - ⁇ [4- (2-ethylhexyloxy) -2-hydroxy] phenyl ⁇ -6- (4-methoxyphenyl) -1,3,5-triazine (INCI: bis -Ethylhexyloxyphenol methoxyphenyl triazine) and 2,4,6-tris- [anilino- (p-carbo-2'-ethyl-1'-hexyloxy)] - 1,3,5-triazine (INCI: ethylhexyl triazone), see above
- the bis-ethylhexyloxyphenol methoxyphenyl triazine in the preparation in a concentration of 0.05 to 4.00% by weight and the ethylhexyl triazone in the preparation in a concentration of 0.1 to 4.5% by weight in each case based on the total weight of the preparation advantageously used according to the invention.
- This combination is particularly preferred
- Embodiments of the present invention which are advantageous according to the invention are characterized in that the total concentration of 2-phenylbenzimidazole-5-sulfonic acid salts and 2-ethylhexyl 2-hydroxybenzoate (INCI: ethylhexyl salicylate) in the preparation is based on 0.05 to 5.00% by weight on the total weight of the preparation.
- the preparation according to the invention contains 2-phenylbenzimidazole-5-sulfonic acid salts and none 2-ethylhexyl 2-hydroxybenzoate (INCI: ethylhexyl salicylate), it is advantageous according to the invention to use this compound in a concentration of 0.1 to 1.5% by weight, based on the total weight of the preparation.
- the preparation according to the invention does not contain 2-phenylbenzimidazole-5-sulfonic acid salts, but instead 2-ethylhexyl 2-hydroxybenzoate (INCI: ethylhexyl salicylate), it is advantageous according to the invention to use this compound in a concentration of 0.05 to 5.00% by weight. , based on the total weight of the preparation.
- the preparation according to the invention contains both 2-phenylbenzimidazole-5-sulfonic acid salts and 2-ethylhexyl 2-hydroxybenzoate (INCI: ethylhexyl salicylate)
- 2-phenylbenzimidazole-5-sulfonic acid salts in a concentration of 0.1 to 3, 00% by weight, based on the total weight of the preparation and the 2-ethylhexyl 2-hydroxybenzoate (INCI: ethylhexyl salicylate) sulfonic acid salts used in a concentration of 0.05 to 5.00% by weight, based on the total weight of the preparation.
- This combination is particularly preferred according to the invention.
- the preparation contains a combination of phenoxyethanol and tocopheryl acetate or tocopherol.
- the preparation contains from 0.1 to 0.9% by weight of phenoxyethanol and from 0.05 to 0.5% by weight of tocopheryl acetate, in each case based on the total weight of the preparation.
- Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation comprises one or more of the perfumes hexyl salicylate, linaylacetate, 2-isobutyl-4-hydroxy-4-methyltetrahydropyran, adipic acid diester, methylheptenone, alpha-isomethylionone, butylphenylmethylpropioal, coumarin, limumarin, hexumarin, hexumarin — linalool, diethyl succinate, hydroxyisohexyl 3-cyclohexenecarboxaldehyde, diethyl succinate, menthyl PCA and citronellylmethyl crotonate, benzyl benzoate, alpha-isomethyl ionone, benzyl alcohol, benzyl cinnamate, benzyl salicylate, citronellol, eugenol, geraniol.
- Embodiments which are advantageous according to the invention are further characterized in that the preparation comprises ethylhexylglycerol, propylene glycol, butylene glycol, 2-methylpropane-1,3-diol, 1,2-pentanediol, 1,2-hexanediol, 1,2-octanediol and / or 1,2 -Decanediol contains.
- the preparation contains no parabens and also no methylisothiazolinone, chloromethylisothiazolinone and DMDM hydantoin, that is to say is free from these ingredients.
- the preparation according to the invention usually represents an oil-in-water emulsion (O / W emulsion). This may contain the ingredients customary for such preparations.
- the preparation according to the invention can advantageously contain humectants.
- humectant moistureturizer
- substances or mixtures of substances which impart to cosmetic preparations the property after the application or distribution on the skin surface, the release of moisture in the horny layer (also called t rans e pidermal w ater l oss (TEWL)) to reduce and / or to positively influence the hydration of the horny layer.
- TEWL t rans e pidermal w ater l oss
- moisturizers in the context of the present invention are, for example, glycerol, lactic acid and / or lactates, in particular sodium lactate, butylene glycol, propylene glycol, biosaccaride Gum-1, glycine soy, ethylhexyloxyglycerol, pyrrolidonecarboxylic acid and urea.
- polymeric moisturizers from the group of water-soluble and / or water-swellable and / or with Using water gellable polysaccharides to use.
- hyaluronic acid chitosan and / or a fucose-rich polysaccharide
- chitosan and / or a fucose-rich polysaccharide which is filed in the Chemical Abstracts under the registration number 178463-23-5 and z. B. is available under the name Fucogel®1000 from the company SOLABIA SA.
- Moisturizers can also be used advantageously as anti-wrinkle ingredients to protect against skin changes, such as those found in z. B. occur in skin aging, are used.
- the cosmetic preparations according to the invention can furthermore advantageously, although not necessarily, contain fillers which, for. B. further improve the sensory and cosmetic properties of the formulations and, for example, cause or intensify a velvety or silky feeling on the skin.
- Advantageous fillers for the purposes of the present invention are starch and starch derivatives (such as tapioca starch, distarch phosphate, aluminum or sodium starch, octenyl succinate and the like), pigments which have neither mainly UV filter nor coloring effects (such as e.g. B. Boron nitride, etc.) and / or Aerosile® (CAS No. 7631-86-9) and / or talc and / or polyethylene, nylon, silica, dimethyl silyate.
- starch and starch derivatives such as tapioca starch, distarch phosphate, aluminum or sodium starch, octenyl succinate and the like
- pigments which have neither mainly UV filter nor coloring effects such as e.
- the preparation according to the invention contains silica dimethyl silylates.
- Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation comprises one or more oils selected from the group of the compounds butylene glycol dicaprylate / dicaprate, phenethyl benzoate, C12-15 alkyl benzoate, dibutyl adipate; Diisopropyl sebacate, dicaprylyl carbonate, di-C12-13 alkyl tartrate, butyl octyl salicylate, diethylhexyl syringylidene malonate, hydragenated castor oil dimerate, triheptanoin, C12-13 alkyl lactate, C16-17 alkyl benzoate, propylheptyl caprylric, tricyllic, triglylic, triglylic, caprylic acid, caprylic -Naphthalates, octyldodecanol, caprylic / capric triglycerides, ethyl
- the preparation contains dibutyl adipate, dicaprylyl carbonate and / or C12-C15 alkyl benzoate.
- the water phase of the preparations according to the invention can advantageously contain customary cosmetic auxiliaries, such as, for example, alcohols, in particular those with a low C number, preferably ethanol and / or isopropanol or polyols with a low C number, and also their ethers, preferably propylene glycol, glycerol, electrolytes, self-tanners and in particular a or more thickeners, which one or which can advantageously be chosen from the Group silicon dioxide, aluminum silicates, polysaccharides or their derivatives, e.g. B.
- customary cosmetic auxiliaries such as, for example, alcohols, in particular those with a low C number, preferably ethanol and / or isopropanol or polyols with a low C number, and also their ethers, preferably propylene glycol, glycerol, electrolytes, self-tanners and in particular a or more thickeners, which one or which can advantageously be chosen from the Group silicon
- hyaluronic acid, xanthan gum, hydroxypropylmethyl cellulose particularly advantageously from the group of polyacrylates, preferably a polyacrylate from the group of so-called carbopoles, for example carbopoles of types 980, 981, 1382, 2984, 5984, each individually or in combination.
- Further advantageous thickeners according to the invention are those with the INCI name Acrylates / C10-30 Alkyl Acrylate Crosspolymer (e.g. Pemulen TR 1, Pemulen TR 2, Carbopol 1328 from NOVEON) and Aristoflex AVC (INCI: Ammonium Acryloyldimethyltaurate / VP Copolymer).
- the preparation contains xanthan gum, crosslinked acrylate / C10-C30 alkyl acrylate polymer and / or vinylpyrrolidone / hexadecene copolymer.
- a glycerol content of at least 5% by weight, based on the total weight of the preparation, is particularly advantageous according to the invention.
- the preparation according to the invention contains ethanol.
- Embodiments of the present invention which are advantageous according to the invention are characterized in that the preparation comprises one or more compounds selected from the group of the compounds alpha-lipoic acid, folic acid, phytoene, D-biotin, coenzyme Q10, alpha-glucosylrutin, carnitine, carnosine, natural and / or synthetic isoflavonoids, flavonoids, creatine, creatinine, taurine, ß-alanine, panthenol, magnolol, honokiol, tocopheryl acetate, dihydroxyacetone; Contains 8-hexadecen-1,16-dicarboxylic acid, glycerylglycose, (2-hydroxyethyl) urea, hyaluronic acid and / or their salts and / or licochalcone A.
- film formers are substances of different compositions which are characterized by the following property: if a film former is dissolved in water or other suitable solvents and the solution is then applied to the skin, it forms a film after the solvent has evaporated , which essentially serves to fix the light filter on the skin and thus increase the water resistance of the product.
- polyvinylpyrrolidone PVP
- Copolymers of polyvinylpyrrolidone for example the PVP hexadecene copolymer and the PVP eicosen copolymer, which are available under the trade names Antaron V216 and Antaron V220 from GAF Chemicals Cooperation, are particularly preferred.
- polystyrene sulfonate which is sold under the trade name Flexan 130 by the National Starch and Chemical Corp. is available, and / or polyisobutene, available from Rewo under the trade name Rewopal PIB1000.
- suitable polymers are, for example, polyacrylamides (Seppigel 305), polyvinyl alcohols, PVP, PVP / VA copolymers, polyglycols, acrylate / octylacralymid copolymer (Dermacryl 79).
- hydrogenated castor oil dimerdilinoleate (CAS 646054-62-8, INCI Hydrogenated Castor Oil Dimer Dilinoleate), which can be purchased from Kokyu Alcohol Kogyo under the name Risocast DA-H or PPG-3 benzyl ether myristate ( CAS 403517-45-3), which can be purchased under the trade name Crodamol STS from Croda Chemicals.
- the resulting initial stains were characterized by colorimetry by measuring the yellowness with the spectro-color colorimeter (Dr. Lange); Color measurement software: spectral-QC, version measurement geometry: d / 8 °, gloss component excluded, light type: D65 (corresponding to medium daylight), calibration standard: LZM 268, measurement aperture: 10mm, sample background: base paper without optical brightener, test climate: 21 ° C ( ⁇ 1 ° C), 41% ( ⁇ 4%) rel. Humidity.
- the change in the b-value from the CIE-Lab color measurement system was used for the evaluation.
- the B axis characterizes the color impression yellow / blue, whereby positive b values stand for an increase in the yellow component. The higher the b-value, the greater the yellow impression.
- test rags were washed separately in the Linitest Plus (Atlas) dyeing and washing fastness device (60 ° C, 1h, 20rpm, Ariel Compact powder detergent, 10 metal balls as an additional charge) and then rinsed (20 ° C, 15min, tap water) ).
- Linitest Plus Align Plus
- the CIE-Lab System or L * a * b * color space is a three-dimensional measuring space in which all perceptible colors are contained.
- the color space is constructed on the basis of counter-color theory.
- One of the most important properties of the L * a * b * color model is its device independence, which means that the colors are defined independently of the way in which they are created and reproduced.
- the corresponding EU directive is DIN EN ISO 11664-4 "Colorimetry - Part 4: CIE 1976 L * a * b * color space”.
- the coordinates of the CIELAB plane are formed from the red / green value a and the yellow / blue value b.
- the brightness axis L is perpendicular to this plane.
- L, a and b are to be written with * in order to stand out against others, e.g. to delineate the "Hunter Lab" system.
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102017200723.0A DE102017200723A1 (de) | 2017-01-18 | 2017-01-18 | Octocrylenfreies Sonnenschutzmittel mit Polyglyceryl-10 Stearat |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP3351236A1 EP3351236A1 (de) | 2018-07-25 |
| EP3351236B1 true EP3351236B1 (de) | 2020-05-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| EP18150549.6A Active EP3351236B1 (de) | 2017-01-18 | 2018-01-08 | Octocylenfreies sonnenschutzmittel mit polyglyceryl-10 stearat |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP3351236B1 (zh) |
| CN (1) | CN108392432A (zh) |
| AU (1) | AU2018200385A1 (zh) |
| BR (1) | BR102018000894A2 (zh) |
| DE (1) | DE102017200723A1 (zh) |
| ES (1) | ES2810928T3 (zh) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102017201235A1 (de) | 2017-01-26 | 2018-07-26 | Beiersdorf Ag | Verwendung von Dimethylaminohydroxybenzoylhexylbenzoat in kosmetischen Sonnenschutzmitteln |
| JP7057066B2 (ja) * | 2017-03-02 | 2022-04-19 | 株式会社 資生堂 | 水中油型乳化日焼け止め化粧料 |
| DE102017204792A1 (de) | 2017-03-22 | 2018-09-27 | Beiersdorf Ag | Sonnenschutzmittel mit Polyglyceryl-10 Stearat und Linalool |
| DE102017204794A1 (de) | 2017-03-22 | 2018-09-27 | Beiersdorf Ag | Sonnenschutzmittel mit Triacontanyl PVP |
| DE102017204793A1 (de) | 2017-03-22 | 2018-09-27 | Beiersdorf Ag | Sonnenschutzmittel mit Polyglyceryl-10 Stearat und Polyclyceryl-2 Caprat |
| DE102017204791A1 (de) | 2017-03-22 | 2018-09-27 | Beiersdorf Ag | Sonnenschutzmittel mit Polyglyceryl-10 Stearat und Citronellol |
| DE102017213219A1 (de) * | 2017-08-01 | 2019-02-07 | Beiersdorf Ag | Sonnenschutzmittel mit geringen Augenreizungspotential |
| CN113573694A (zh) | 2019-03-15 | 2021-10-29 | 巴斯夫欧洲公司 | 具有二乙氨基羟基苯甲酰基苯甲酸己酯和有机颗粒状uv过滤剂的有效防晒组合物 |
| BR112021017072A2 (pt) | 2019-03-15 | 2021-11-09 | Basf Se | Composição de protetor solar ou cuidados diários, e, uso de hexil 2-[4-(dietilamino)-2-hidroxibenzoil]benzoato (inci dietilamino hidroxibenzoil hexil benzoato) e um filtro uv orgânico particulado |
| BR112021017063A2 (pt) | 2019-03-15 | 2021-11-09 | Basf Se | Composição de protetor solar ou cuidado diário, e, uso de uma composição de protetor solar ou cuidado diário |
| KR20210138667A (ko) | 2019-03-15 | 2021-11-19 | 바스프 에스이 | 디에틸아미노 히드록시벤조일 헥실 벤조에이트 및 수용성 uva 필터를 갖는 효율적인 선스크린 조성물 |
| JP7551640B2 (ja) | 2019-03-15 | 2024-09-17 | ベーアーエスエフ・エスエー | ジエチルアミノヒドロキシベンゾイル安息香酸ヘキシル及びブチルメトキシジベンゾイルメタンを含む効果的な日焼け止め組成物 |
| FR3095757B1 (fr) * | 2019-05-10 | 2021-05-21 | Fabre Pierre Dermo Cosmetique | Système photoprotecteur constitué de 4 filtres solaires |
| WO2021102874A1 (en) * | 2019-11-29 | 2021-06-03 | Beiersdorf Daily Chemical (Wuhan) Co., Ltd. | An oil-in-water sunscreen composition |
| DE102020201799A1 (de) * | 2020-02-13 | 2021-08-19 | Beiersdorf Aktiengesellschaft | Polyacrylat-freie kosmetische Zubereitung |
| LU101670B1 (en) * | 2020-03-09 | 2021-09-10 | Soc De Recherche Cosmetique Sarl | Sun protection topical composition |
| CN115279334A (zh) * | 2020-03-13 | 2022-11-01 | 巴斯夫欧洲公司 | 包含香料的抗老化护理组合物 |
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| DE102007024346A1 (de) * | 2007-05-22 | 2008-11-27 | Beiersdorf Ag | Kosmetische Zubereitung mit ionischem UV-A-Filter und 2-(4'-Diethylamino-2'hydoxybenzoyl)-benzoesäurehexylester |
| DE102008021631A1 (de) * | 2008-04-25 | 2009-10-29 | Beiersdorf Ag | Lichtschutzfilterkombination mit 2,4,6-Tris-(biphenyl)-1,3,5-triazin |
| DE102011077037A1 (de) * | 2011-06-07 | 2012-12-13 | Beiersdorf Ag | Kosmetische oder dermatologische Lichtschutzzubereitung mit verbesserter Wasserfestigkeit |
| WO2012168286A2 (en) * | 2011-06-08 | 2012-12-13 | Dsm Ip Assets B.V. | Topical composition |
| DE102011088962A1 (de) | 2011-12-19 | 2013-06-20 | Beiersdorf Ag | Wirkstoffkombinationen aus einer oder mehreren Carbonsäuren, insbesondereHydroxycarbonsäuren, und einer oder mehreren physiologisch unbedenklichen Hydroxamsäure sowie kosmetische oder dermatologische Zubereitungen, solcheWirkstoffkombinationen enthaltend |
| DE102013200819A1 (de) | 2013-01-18 | 2014-07-24 | Beiersdorf Ag | Wirkstoffkombinationen aus Dehydracetsäure und einem oder mehrere Polyolen |
| DE102013213175A1 (de) | 2013-07-04 | 2015-01-08 | Beiersdorf Ag | Sonnenschutzmittel mit hohem Triazingehalt |
| DE102013213170A1 (de) | 2013-07-04 | 2015-01-08 | Beiersdorf Ag | Octocrylenfreies, geruchsstabiles Sonnenschutzmittel |
| DE102013213174A1 (de) * | 2013-07-04 | 2015-01-08 | Beiersdorf Ag | Octocrylenfreies Sonnenschutzmittel |
| DE102014201541A1 (de) * | 2014-01-29 | 2015-07-30 | Beiersdorf Ag | Octocrylenfreies Sonnenschutzmittel mit geringer Klebrigkeit |
| DE102014202956A1 (de) | 2014-02-18 | 2015-08-20 | Beiersdorf Ag | Kosmetische Emulgatorkombination |
| DE102014207602A1 (de) | 2014-04-23 | 2015-10-29 | Beiersdorf Ag | Emulsionsgrundlage für Sonnenschutzmittel |
| DE102014216602A1 (de) | 2014-08-21 | 2016-02-25 | Beiersdorf Ag | Stabile kosmetische Zubereitung |
| DE102015211792A1 (de) | 2015-06-25 | 2016-12-29 | Beiersdorf Ag | Sonnenschutzmittel mit Ausgangsstoff für die Bildung von 4-(tert.-Butyl)-4'-methoxydibenzoylmethan |
| DE102015211790A1 (de) | 2015-06-25 | 2016-12-29 | Beiersdorf Ag | Ethanolisches Sonnenschutzmittel mit Ausgangsstoff für die Bildung von 4-(tert.-Butyl)-4'-methoxydibenzoylmethan |
| DE102015212122A1 (de) | 2015-06-25 | 2016-12-29 | Beiersdorf Ag | Sprühbares Sonnenschutzmittel mit definierter Wachsmischung |
| DE102015211793A1 (de) | 2015-06-25 | 2016-12-29 | Beiersdorf Ag | Alkandiol-haltige Sonnenschutzmittel mit Ausgangsstoff für die Bildung von 4-(tert.-Butyl)-4'-methoxydibenzoylmethan |
-
2017
- 2017-01-18 DE DE102017200723.0A patent/DE102017200723A1/de not_active Withdrawn
-
2018
- 2018-01-08 ES ES18150549T patent/ES2810928T3/es active Active
- 2018-01-08 EP EP18150549.6A patent/EP3351236B1/de active Active
- 2018-01-16 BR BR102018000894A patent/BR102018000894A2/pt not_active Application Discontinuation
- 2018-01-17 AU AU2018200385A patent/AU2018200385A1/en not_active Abandoned
- 2018-01-17 CN CN201810043617.XA patent/CN108392432A/zh active Pending
Non-Patent Citations (1)
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| None * |
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| ES2810928T3 (es) | 2021-03-09 |
| AU2018200385A1 (en) | 2018-08-02 |
| DE102017200723A1 (de) | 2018-07-19 |
| CN108392432A (zh) | 2018-08-14 |
| EP3351236A1 (de) | 2018-07-25 |
| BR102018000894A2 (pt) | 2018-10-30 |
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