EP3328436A4 - Pharmazeutische zusammensetzung mit verbesserter lagerstabilität und verfahren zur herstellung davon - Google Patents
Pharmazeutische zusammensetzung mit verbesserter lagerstabilität und verfahren zur herstellung davon Download PDFInfo
- Publication number
- EP3328436A4 EP3328436A4 EP16830852.6A EP16830852A EP3328436A4 EP 3328436 A4 EP3328436 A4 EP 3328436A4 EP 16830852 A EP16830852 A EP 16830852A EP 3328436 A4 EP3328436 A4 EP 3328436A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- preparing
- pharmaceutical composition
- same
- storage stability
- improved storage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020150106628A KR101787447B1 (ko) | 2015-07-28 | 2015-07-28 | 보관 안정성이 향상된 약학 조성물 및 그의 제조 방법 |
PCT/KR2016/008269 WO2017018819A1 (en) | 2015-07-28 | 2016-07-28 | Pharmaceutical composition with improved storage stability and method for preparing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3328436A1 EP3328436A1 (de) | 2018-06-06 |
EP3328436A4 true EP3328436A4 (de) | 2019-03-20 |
Family
ID=57884931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP16830852.6A Withdrawn EP3328436A4 (de) | 2015-07-28 | 2016-07-28 | Pharmazeutische zusammensetzung mit verbesserter lagerstabilität und verfahren zur herstellung davon |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP3328436A4 (de) |
JP (1) | JP2018521106A (de) |
KR (1) | KR101787447B1 (de) |
CN (1) | CN106659680A (de) |
AU (1) | AU2016299547A1 (de) |
BR (1) | BR112018001719A2 (de) |
CA (1) | CA2993923A1 (de) |
HK (1) | HK1249440A1 (de) |
IL (1) | IL257181A (de) |
MX (1) | MX2018001222A (de) |
RU (1) | RU2018107054A (de) |
WO (1) | WO2017018819A1 (de) |
ZA (1) | ZA201801186B (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20190231689A1 (en) * | 2018-01-29 | 2019-08-01 | Samyang Biopharmaceuticals Corporation | Amphiphilic Block Copolymer Composition With Enhanced Micelle Stability |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001085216A1 (en) * | 2000-05-12 | 2001-11-15 | Samyang Corporation | Method for the preparation of polymeric micelle via phase separation of block copolymer |
US8853351B2 (en) * | 2007-12-31 | 2014-10-07 | Samyang Biopharmaceuticals Corporation | Highly pure amphiphilic copolymer comprising hydrophobic block from alpha-hydroxy acid and process for the preparation thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1448707B1 (de) * | 2001-10-18 | 2007-08-22 | Samyang Corporation | Polymermicellenzusammensetzung mit verbesserter stabilität |
ES2353653T3 (es) | 2007-03-06 | 2011-03-03 | Cell Therapeutics Europe S.R.L. | Método para determinar la cantidad de taxano conjugado en conjugados de ácido poliglutámico-taxano. |
KR101024742B1 (ko) * | 2007-12-31 | 2011-03-24 | 주식회사 삼양사 | 탁산 함유 양친성 블록 공중합체 미셀 조성물 및 그 제조방법 |
EP2201935B1 (de) * | 2008-12-26 | 2020-07-08 | Samyang Biopharmaceuticals Corporation | Polymere Mizellenzusammensetzung, die ein schlecht lösliches Arzneimittel enthält, und zugehöriges Herstellungsverfahren |
-
2015
- 2015-07-28 KR KR1020150106628A patent/KR101787447B1/ko active IP Right Grant
-
2016
- 2016-07-28 MX MX2018001222A patent/MX2018001222A/es unknown
- 2016-07-28 JP JP2018504276A patent/JP2018521106A/ja active Pending
- 2016-07-28 WO PCT/KR2016/008269 patent/WO2017018819A1/en active Application Filing
- 2016-07-28 CN CN201680001944.8A patent/CN106659680A/zh active Pending
- 2016-07-28 BR BR112018001719A patent/BR112018001719A2/pt not_active Application Discontinuation
- 2016-07-28 EP EP16830852.6A patent/EP3328436A4/de not_active Withdrawn
- 2016-07-28 RU RU2018107054A patent/RU2018107054A/ru unknown
- 2016-07-28 CA CA2993923A patent/CA2993923A1/en not_active Abandoned
- 2016-07-28 AU AU2016299547A patent/AU2016299547A1/en not_active Abandoned
-
2018
- 2018-01-28 IL IL257181A patent/IL257181A/en unknown
- 2018-02-21 ZA ZA2018/01186A patent/ZA201801186B/en unknown
- 2018-07-13 HK HK18109125.9A patent/HK1249440A1/zh unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001085216A1 (en) * | 2000-05-12 | 2001-11-15 | Samyang Corporation | Method for the preparation of polymeric micelle via phase separation of block copolymer |
US8853351B2 (en) * | 2007-12-31 | 2014-10-07 | Samyang Biopharmaceuticals Corporation | Highly pure amphiphilic copolymer comprising hydrophobic block from alpha-hydroxy acid and process for the preparation thereof |
Non-Patent Citations (2)
Title |
---|
R.T. LIGGINS ET AL: "Polyether-polyester diblock copolymers for the preparation of paclitaxel loaded polymeric micelle formulations", ADVANCED DRUG DELIVERY REVIEWS, vol. 54, no. 2, 1 February 2002 (2002-02-01), pages 191 - 202, XP055084423, ISSN: 0169-409X, DOI: 10.1016/S0169-409X(02)00016-9 * |
See also references of WO2017018819A1 * |
Also Published As
Publication number | Publication date |
---|---|
RU2018107054A (ru) | 2019-08-28 |
BR112018001719A2 (pt) | 2018-09-18 |
HK1249440A1 (zh) | 2018-11-02 |
ZA201801186B (en) | 2018-12-19 |
EP3328436A1 (de) | 2018-06-06 |
CA2993923A1 (en) | 2017-02-02 |
JP2018521106A (ja) | 2018-08-02 |
IL257181A (en) | 2018-03-29 |
AU2016299547A1 (en) | 2018-02-22 |
MX2018001222A (es) | 2018-04-24 |
KR101787447B1 (ko) | 2017-10-19 |
WO2017018819A1 (en) | 2017-02-02 |
RU2018107054A3 (de) | 2019-08-28 |
KR20170014059A (ko) | 2017-02-08 |
CN106659680A (zh) | 2017-05-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL289099A (en) | Methods for storage of whole blood, and corresponding preparations | |
EP3364951A4 (de) | Nikotinzusammensetzung für e-zigarette und e-zigaretten damit | |
EP3197867A4 (de) | Neuartige 4-methoxypyrrolderivate oder salze davon und pharmazeutische zusammensetzung damit | |
EP3328562A4 (de) | Clean-in-place-verfahren, system und zusammensetzung dafür | |
EP3319710A4 (de) | Zusammensetzung und system zur gasspeicherung | |
EP3130355A4 (de) | Pharmazeutische zusammensetzung mit pregabalin mit verbesserter stabilität und verfahren zur herstellung davon | |
EP3331947A4 (de) | Kieselsäurebasierter biomolekülträger, pharmazeutische zusammensetzung damit, herstellungsverfahren und verwendung davon | |
EP3330379A4 (de) | Aptamer gegen insulinrezeptor und pharmazeutische zusammensetzung damit | |
HRP20200104T8 (hr) | Novi heterociklični spoj, metoda za pripremu istog, i farmaceutska kompozicija koja sadrži isto | |
EP3207149A4 (de) | Pharmazeutische zusammensetzung mit verbesserter stabilität | |
EP3185873A4 (de) | Pharmazeutische zusammensetzung und verfahren | |
EP3328368A4 (de) | Verbindungen und pharmazeutische zusammensetzung im zusammenhang mit dem ubiquitination-proteasom-system | |
EP3384933A4 (de) | Anhydrozucker-alkohol-zusammensetzung mit verbesserter lagerstabilität und anhydrozucker-alkohol-lagerungsverfahren | |
HK1249439A1 (zh) | 具有改善的儲存穩定性的藥物組合物及其製備方法 | |
HK1249442A1 (zh) | 具有改善的儲存穩定性的藥物組合物及其製備方法 | |
EP3349748A4 (de) | Zusammensetzung und verfahren dafür | |
EP3175845A4 (de) | Pharmazeutische zusammensetzung mit funktion zur verhinderung von missbrauch | |
EP3305283A4 (de) | Stabilisierte pharmazeutische zusammensetzung und verfahren zur herstellung davon | |
HK1249440A1 (zh) | 具有改善的儲存穩定性的藥物組合物及其製備方法 | |
EP3230940A4 (de) | Verfahren zur herstellung eines interaktiven digitalen katalogs und computerlesbares speichermedium sowie interaktiver digitaler katalog damit | |
EP3143017A4 (de) | Bicyclische derivate und pharmazeutische zusammensetzung damit | |
EP3175851A4 (de) | Verwendung von butenylphthalid, verwendungsverfahren dafür und verfahren zur zubereitung davon in eine pharmazeutische zusammensetzung | |
HK1249441A1 (zh) | 具有改善的儲存穩定性的藥物組合物及其製備方法 | |
EP3310761A4 (de) | Blutplättchenspeicherverfahren und zusammensetzungen dafür | |
EP3251672A4 (de) | Pharmazeutische zusammensetzung und herstellungsverfahren dafür |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20180228 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1249440 Country of ref document: HK |
|
DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20190218 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 47/32 20060101ALI20190212BHEP Ipc: A61K 47/34 20170101ALI20190212BHEP Ipc: A61K 31/337 20060101ALI20190212BHEP Ipc: A61K 31/122 20060101ALI20190212BHEP Ipc: A61K 47/30 20060101AFI20190212BHEP Ipc: A61K 9/107 20060101ALI20190212BHEP |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20190918 |